{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:13:40Z","timestamp":1793402020260,"version":"4.5.0"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T00:00:00Z","timestamp":1560902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T00:00:00Z","timestamp":1560902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470816,61431013"],"award-info":[{"award-number":["81470816,61431013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81730016"],"award-info":[{"award-number":["81730016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Natural Science Foundation of Shaanxi Province","award":["2018JM3007"],"award-info":[{"award-number":["2018JM3007"]}]},{"name":"National Clinical Research Center for Digestive Diseases, Xi'an, China","award":["2015BAI13B07"],"award-info":[{"award-number":["2015BAI13B07"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Imaging and Behavior"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s11682-019-00133-4","type":"journal-article","created":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T12:05:35Z","timestamp":1560945935000},"page":"1899-1907","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Cortical morphometry alterations in brain regions involved in emotional, motor-control and self-referential processing in patients with functional constipation"],"prefix":"10.1007","volume":"14","author":[{"given":"Chunxin","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junwang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenchao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhida","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen M.","family":"von Deneen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijun","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangbin","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongzhan","family":"Nie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,6,19]]},"reference":[{"issue":"4","key":"133_CR1","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/0016-5085(94)90753-6","volume":"106","author":"A Aggarwal","year":"1994","unstructured":"Aggarwal, A., Cutts, T. F., Abell, T. L., Cardoso, S., Familoni, B., Bremer, J., et al. (1994). Predominant symptoms in irritable bowel syndrome correlate with specific autonomic nervous system abnormalities. Gastroenterology, 106(4), 945\u2013950.","journal-title":"Gastroenterology"},{"issue":"5","key":"133_CR2","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1053\/j.gastro.2012.07.104","volume":"143","author":"E Aizawa","year":"2012","unstructured":"Aizawa, E., Sato, Y., Kochiyama, T., Saito, N., Izumiyama, M., Morishita, J., et al. (2012). Altered cognitive function of prefrontal cortex during error feedback in patients with irritable bowel syndrome, based on FMRI and dynamic causal modeling. Gastroenterology, 143(5), 1188\u20131198.","journal-title":"Gastroenterology"},{"issue":"1","key":"133_CR3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1055\/s-0032-1301753","volume":"25","author":"AM Alame","year":"2012","unstructured":"Alame, A. M., & Bahna, H. (2012). Evaluation of constipation. Clinics in Colon and Rectal Surgery, 25(1), 5\u201311.","journal-title":"Clinics in Colon and Rectal Surgery"},{"issue":"4","key":"133_CR4","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ejpain.2004.11.001","volume":"9","author":"AV Apkarian","year":"2005","unstructured":"Apkarian, A. V., Bushnell, M. C., Treede, R. D., & Zubieta, J. K. (2005). Human brain mechanisms of pain perception and regulation in health and disease. European Journal of Pain, 9(4), 463\u2013484.","journal-title":"European Journal of Pain"},{"issue":"5","key":"133_CR5","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1097\/j.pain.0000000000000479","volume":"157","author":"CH Bao","year":"2016","unstructured":"Bao, C. H., Liu, P., Liu, H. R., Wu, L. Y., Jin, X. M., Wang, S. Y., et al. (2016). Differences in regional homogeneity between patients with Crohn's disease with and without abdominal pain revealed by resting-state functional magnetic resonance imaging. Pain, 157(5), 1037\u20131044.","journal-title":"Pain"},{"issue":"5","key":"133_CR6","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1053\/j.gastro.2009.12.043","volume":"138","author":"U Blankstein","year":"2010","unstructured":"Blankstein, U., Chen, J., Diamant, N. E., & Davis, K. D. (2010). Altered brain structure in irritable bowel syndrome: Potential contributions of pre-existing and disease-driven factors. Gastroenterology, 138(5), 1783\u20131789.","journal-title":"Gastroenterology"},{"issue":"6","key":"133_CR7","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1097\/00000441-192812000-00006","volume":"176","author":"H Bockus","year":"1928","unstructured":"Bockus, H., Bank, J., & Wilkinson, S. (1928). Neurogenic mucous colitis. American Journal of the Medical Sciences, 176(6), 813\u2013829.","journal-title":"American Journal of the Medical Sciences"},{"issue":"5","key":"133_CR8","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.jpeds.2008.11.029","volume":"154","author":"ME Bongers","year":"2009","unstructured":"Bongers, M. E., van Dijk, M., Benninga, M. A., & Grootenhuis, M. A. (2009). Health related quality of life in children with constipation-associated fecal incontinence. Journal of Pediatrics, 154(5), 749\u2013753.","journal-title":"Journal of Pediatrics"},{"issue":"5","key":"133_CR9","first-page":"E337","volume":"13","author":"A Buvanendran","year":"2010","unstructured":"Buvanendran, A., Ali, A., Stoub, T. R., Kroin, J. S., & Tuman, K. J. (2010). Brain activity associated with chronic cancer pain. Pain Physician, 13(5), E337\u2013E342.","journal-title":"Pain Physician"},{"issue":"Pt 3","key":"133_CR10","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/brain\/awl004","volume":"129","author":"AE Cavanna","year":"2006","unstructured":"Cavanna, A. E., & Trimble, M. R. (2006). The precuneus: A review of its functional anatomy and behavioural correlates. Brain, 129(Pt 3), 564\u2013583.","journal-title":"Brain"},{"issue":"8","key":"133_CR11","volume":"12","author":"CS Chua","year":"2017","unstructured":"Chua, C. S., Bai, C. H., Shiao, C. Y., Hsu, C. Y., Cheng, C. W., Yang, K. C., et al. (2017). Negative correlation of cortical thickness with the severity and duration of abdominal pain in Asian women with irritable bowel syndrome. PLoS One, 12(8), e0183960.","journal-title":"PLoS One"},{"issue":"2","key":"133_CR12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1006\/nimg.1998.0395","volume":"9","author":"AM Dale","year":"1999","unstructured":"Dale, A. M., Fischl, B., & Sereno, M. I. (1999). Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage, 9(2), 179\u2013194.","journal-title":"Neuroimage"},{"key":"133_CR13","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s12876-015-0366-3","volume":"15","author":"R De Giorgio","year":"2015","unstructured":"De Giorgio, R., Ruggeri, E., Stanghellini, V., Eusebi, L. H., Bazzoli, F., & Chiarioni, G. (2015). Chronic constipation in the elderly: A primer for the gastroenterologist. BMC Gastroenterology, 15, 130.","journal-title":"BMC Gastroenterology"},{"issue":"3","key":"133_CR14","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/nmo.12785","volume":"28","author":"BY De Winter","year":"2016","unstructured":"De Winter, B. Y., Deiteren, A., & De Man, J. G. (2016). Novel nervous system mechanisms in visceral pain. Neurogastroenterology and Motility, 28(3), 309\u2013315.","journal-title":"Neurogastroenterology and Motility"},{"key":"133_CR15","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1053\/j.gastro.2016.02.032","volume":"150","author":"DA Drossman","year":"2016","unstructured":"Drossman, D. A. (2016). Functional gastrointestinal disorders: History, pathophysiology, clinical features and Rome IV. Gastroenterology., 150, 1262\u20131279.e2.","journal-title":"Gastroenterology."},{"issue":"1","key":"133_CR16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1515\/sjpain-2017-0153","volume":"18","author":"H Edebol-Carlman","year":"2018","unstructured":"Edebol-Carlman, H., Schrooten, M., Ljotsson, B., Boersma, K., Linton, S., & Brummer, R. J. (2018). Cognitive behavioral therapy for irritable bowel syndrome: The effects on state and trait anxiety and the autonomic nervous system during induced rectal distensions - an uncontrolled trial. Scandinavian Journal of Pain, 18(1), 81\u201391.","journal-title":"Scandinavian Journal of Pain"},{"issue":"20","key":"133_CR17","doi-asserted-by":"crossref","first-page":"11050","DOI":"10.1073\/pnas.200033797","volume":"97","author":"B Fischl","year":"2000","unstructured":"Fischl, B., & Dale, A. M. (2000). Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proceedings of the National Academy of Sciences of the United States of America, 97(20), 11050\u201311055.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"9","key":"133_CR18","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/nimg.1998.0396","volume":"2","author":"B Fischl","year":"1999","unstructured":"Fischl, B., Sereno, M., & Dale, A. M. (1999). Cortical surface-based anlaysis. II: Inflation, flattening, and a surface-based coordinate system. Neuroimage, 2(9), 195\u2013207.","journal-title":"Neuroimage"},{"issue":"Suppl 1","key":"133_CR19","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1016\/j.neuroimage.2004.07.016","volume":"23","author":"B Fischl","year":"2004","unstructured":"Fischl, B., Salat, D. H., van der Kouwe, A. J., Makris, N., Segonne, F., Quinn, B. T., et al. (2004). Sequence-independent segmentation of magnetic resonance images. Neuroimage, 23(Suppl 1), S69\u2013S84.","journal-title":"Neuroimage"},{"issue":"Suppl 3","key":"133_CR20","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1440-1746.2011.06631.x","volume":"26","author":"S Fukudo","year":"2011","unstructured":"Fukudo, S., & Kanazawa, M. (2011). Gene, environment, and brain-gut interactions in irritable bowel syndrome. Journal of Gastroenterology and Hepatology, 26(Suppl 3), 110\u2013115.","journal-title":"Journal of Gastroenterology and Hepatology"},{"issue":"31","key":"133_CR21","doi-asserted-by":"crossref","first-page":"10686","DOI":"10.1523\/JNEUROSCI.0727-12.2012","volume":"32","author":"S Gluth","year":"2012","unstructured":"Gluth, S., Rieskamp, J., & Buchel, C. (2012). Deciding when to decide: Time-variant sequential sampling models explain the emergence of value-based decisions in the human brain. Journal of Neuroscience, 32(31), 10686\u201310698.","journal-title":"Journal of Neuroscience"},{"issue":"3","key":"133_CR22","doi-asserted-by":"crossref","first-page":"415","DOI":"10.5056\/jnm16148","volume":"23","author":"A Guleria","year":"2017","unstructured":"Guleria, A., Karyampudi, A., Singh, R., Khetrapal, C. L., Verma, A., Ghoshal, U. C., et al. (2017). Mapping of brain activations to rectal balloon distension stimuli in male patients with irritable bowel syndrome using functional magnetic resonance imaging. Journal of Neurogastroenterology and Motility, 23(3), 415\u2013427.","journal-title":"Journal of Neurogastroenterology and Motility"},{"issue":"3","key":"133_CR23","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1007\/s00429-015-0996-9","volume":"221","author":"A Gupta","year":"2016","unstructured":"Gupta, A., Labus, J., Kilpatrick, L. A., Bonyadi, M., Ashe-McNalley, C., Heendeniya, N., et al. (2016). Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain Structure & Function, 221(3), 1667\u20131679.","journal-title":"Brain Structure & Function"},{"issue":"2","key":"133_CR24","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/hbm.21440","volume":"34","author":"X Hao","year":"2013","unstructured":"Hao, X., Xu, D., Bansal, R., Dong, Z., Liu, J., Wang, Z., et al. (2013). Multimodal magnetic resonance imaging: The coordinated use of multiple, mutually informative probes to understand brain structure and function. Human Brain Mapping, 34(2), 253\u2013271.","journal-title":"Human Brain Mapping"},{"issue":"1","key":"133_CR25","volume":"9","author":"JY Hong","year":"2014","unstructured":"Hong, J. Y., Labus, J. S., Jiang, Z., Ashe-Mcnalley, C., Dinov, I., Gupta, A., et al. (2014). Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. PLoS One, 9(1), e84564.","journal-title":"PLoS One"},{"issue":"1","key":"133_CR26","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/nmo.12710","volume":"28","author":"JY Hong","year":"2016","unstructured":"Hong, J. Y., Naliboff, B., Labus, J. S., Gupta, A., Kilpatrick, L. A., Ashe-McNalley, C., et al. (2016). Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and Motility, 28(1), 127\u2013138.","journal-title":"Neurogastroenterology and Motility"},{"issue":"9","key":"133_CR27","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1111\/nmo.12622","volume":"27","author":"CS Hubbard","year":"2015","unstructured":"Hubbard, C. S., Hong, J., Jiang, Z., Ebrat, B., Suyenobu, B., Smith, S., et al. (2015). Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and Motility, 27(9), 1282\u20131294.","journal-title":"Neurogastroenterology and Motility"},{"issue":"5","key":"133_CR28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0156545","volume":"11","author":"CS Hubbard","year":"2016","unstructured":"Hubbard, C. S., Becerra, L., Heinz, N., Ludwick, A., Rasooly, T., Wu, R., et al. (2016). Abdominal pain, the adolescent and altered brain structure and function. PLoS One, 11(5), e0156545.","journal-title":"PLoS One"},{"issue":"5","key":"133_CR29","volume":"31","author":"Q Jin","year":"2019","unstructured":"Jin, Q., Duan, S., Li, G., Sun, L., Hu, Y., Hu, C., et al. (2019). Sex-related differences in resting-state brain activity and connectivity in the orbital frontal cortex and insula in patients with functional constipation. Neurogastroenterology and Motility, 31(5), e13566.","journal-title":"Neurogastroenterology and Motility"},{"issue":"2","key":"133_CR30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1365-2982.2005.00730.x","volume":"18","author":"MP Jones","year":"2006","unstructured":"Jones, M. P., Dilley, J. B., Drossman, D., & Crowell, M. D. (2006). Brain-gut connections in functional GI disorders: Anatomic and physiologic relationships. Neurogastroenterology and Motility, 18(2), 91\u2013103.","journal-title":"Neurogastroenterology and Motility"},{"issue":"8","key":"133_CR31","doi-asserted-by":"crossref","first-page":"G687","DOI":"10.1152\/ajpgi.00385.2012","volume":"304","author":"M Kano","year":"2013","unstructured":"Kano, M., Farmer, A. D., Aziz, Q., Giampietro, V. P., Brammer, M. J., Williams, S. C., et al. (2013). Sex differences in brain response to anticipated and experienced visceral pain in healthy subjects. American Journal of Physiology Gastrointestinal and Liver Physiology, 304(8), G687\u2013G699.","journal-title":"American Journal of Physiology Gastrointestinal and Liver Physiology"},{"issue":"2","key":"133_CR32","doi-asserted-by":"crossref","first-page":"G141","DOI":"10.1152\/ajpgi.00060.2012","volume":"303","author":"D Keszthelyi","year":"2012","unstructured":"Keszthelyi, D., Troost, F. J., & Masclee, A. A. (2012). Irritable bowel syndrome: Methods, mechanisms, and pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome. American Journal of Physiology Gastrointestinal and Liver Physiology, 303(2), G141\u2013G154.","journal-title":"American Journal of Physiology Gastrointestinal and Liver Physiology"},{"issue":"5","key":"133_CR33","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s40272-015-0142-4","volume":"17","author":"IJ Koppen","year":"2015","unstructured":"Koppen, I. J., Lammers, L. A., Benninga, M. A., & Tabbers, M. M. (2015). Management of Functional Constipation in children: Therapy in practice. Paediatric Drugs, 17(5), 349\u2013360.","journal-title":"Paediatric Drugs"},{"issue":"36","key":"133_CR34","doi-asserted-by":"crossref","first-page":"12950","DOI":"10.1073\/pnas.0408576102","volume":"102","author":"T Koyama","year":"2005","unstructured":"Koyama, T., McHaffie, J. G., Laurienti, P. J., & Coghill, R. C. (2005). The subjective experience of pain: Where expectations become reality. Proceedings of the National Academy of Sciences of the United States of America, 102(36), 12950\u201312955.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"2","key":"133_CR35","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.neuroimage.2006.12.032","volume":"35","author":"JP Kuhtz-Buschbeck","year":"2007","unstructured":"Kuhtz-Buschbeck, J. P., van der Horst, C., Wolff, S., Filippow, N., Nabavi, A., Jansen, O., et al. (2007). Activation of the supplementary motor area (SMA) during voluntary pelvic floor muscle contractions--an fMRI study. Neuroimage, 35(2), 449\u2013457.","journal-title":"Neuroimage"},{"issue":"8","key":"133_CR36","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1212\/01.wnl.0000180971.95473.cc","volume":"65","author":"CL Kwan","year":"2005","unstructured":"Kwan, C. L., Diamant, N. E., Pope, G., Mikula, K., Mikulis, D. J., & Davis, K. D. (2005). Abnormal forebrain activity in functional bowel disorder patients with chronic pain. Neurology, 65(8), 1268\u20131277.","journal-title":"Neurology"},{"issue":"10","key":"133_CR37","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1016\/j.pain.2013.06.024","volume":"154","author":"JS Labus","year":"2013","unstructured":"Labus, J. S., Gupta, A., Coveleskie, K., Tillisch, K., Kilpatrick, L., Jarcho, J., et al. (2013). Sex differences in emotion-related cognitive processes in irritable bowel syndrome and healthy control subjects. Pain, 154(10), 2088\u20132099.","journal-title":"Pain"},{"key":"133_CR38","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2147\/PHMT.S110940","volume":"8","author":"EI Levy","year":"2017","unstructured":"Levy, E. I., Lemmens, R., Vandenplas, Y., & Devreker, T. (2017). Functional constipation in children: Challenges and solutions. Pediatric Health, Medicine and Therapeutics, 8, 19\u201327.","journal-title":"Pediatric Health, Medicine and Therapeutics"},{"key":"133_CR39","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.brainres.2014.12.040","volume":"1599","author":"CH Liu","year":"2015","unstructured":"Liu, C. H., Ma, X., Song, L. P., Tang, L. R., Jing, B., Zhang, Y., et al. (2015). Alteration of spontaneous neuronal activity within the salience network in partially remitted depression. Brain Research, 1599, 93\u2013102.","journal-title":"Brain Research"},{"issue":"1","key":"133_CR40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/nmo.12695","volume":"28","author":"X Liu","year":"2016","unstructured":"Liu, X., Silverman, A., Kern, M., Ward, B. D., Li, S. J., Shaker, R., et al. (2016). Excessive coupling of the salience network with intrinsic neurocognitive brain networks during rectal distension in adolescents with irritable bowel syndrome: A preliminary report. Neurogastroenterology and Motility, 28(1), 43\u201353.","journal-title":"Neurogastroenterology and Motility"},{"key":"133_CR41","doi-asserted-by":"crossref","unstructured":"Liu, L., Ji, G., Li, G., Hu, Y., Jin, Q., Hu, C., et al. (2019). Structural changes in brain regions involved in executive-control and self-referential processing after sleeve gastrectomy in obese patients. Brain Imaging and Behavior, 13(3), 830\u2013840.","DOI":"10.1007\/s11682-018-9904-2"},{"issue":"4","key":"133_CR42","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/cne.903110403","volume":"311","author":"G Luppino","year":"1991","unstructured":"Luppino, G., Matelli, M., Camarda, R. M., Gallese, V., & Rizzolatti, G. (1991). Multiple representations of body movements in mesial area 6 and the adjacent cingulate cortex: An intracortical microstimulation study in the macaque monkey. Journal of Comparative Neurology, 311(4), 463\u2013482.","journal-title":"Journal of Comparative Neurology"},{"issue":"6","key":"133_CR43","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1053\/j.gastro.2006.10.026","volume":"131","author":"EA Mayer","year":"2006","unstructured":"Mayer, E. A., Naliboff, B. D., & Craig, A. D. (2006). Neuroimaging of the brain-gut axis: From basic understanding to treatment of functional GI disorders. Gastroenterology, 131(6), 1925\u20131942.","journal-title":"Gastroenterology"},{"issue":"10","key":"133_CR44","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/nrgastro.2015.121","volume":"12","author":"EA Mayer","year":"2015","unstructured":"Mayer, E. A., Labus, J. S., Tillisch, K., Cole, S. W., & Baldi, P. (2015). Towards a systems view of IBS. Nature Reviews Gastroenterology & Hepatology, 12(10), 592\u2013605.","journal-title":"Nature Reviews Gastroenterology & Hepatology"},{"issue":"8","key":"133_CR45","doi-asserted-by":"crossref","first-page":"CR493","DOI":"10.12659\/MSM.883269","volume":"18","author":"M Mazur","year":"2012","unstructured":"Mazur, M., Furgala, A., Jablonski, K., Mach, T., & Thor, P. (2012). Autonomic nervous system activity in constipation-predominant irritable bowel syndrome patients. Medical Science Monitor, 18(8), CR493\u2013CR499.","journal-title":"Medical Science Monitor"},{"issue":"2","key":"133_CR46","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ejpain.2009.04.011","volume":"14","author":"X Moisset","year":"2010","unstructured":"Moisset, X., Bouhassira, D., Denis, D., Dominique, G., Benoit, C., & Sabate, J. M. (2010). Anatomical connections between brain areas activated during rectal distension in healthy volunteers: A visceral pain network. European Journal of Pain, 14(2), 142\u2013148.","journal-title":"European Journal of Pain"},{"issue":"1","key":"133_CR47","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bpg.2010.12.010","volume":"25","author":"SM Mugie","year":"2011","unstructured":"Mugie, S. M., Benninga, M. A., & Di Lorenzo, C. (2011). Epidemiology of constipation in children and adults: A systematic review. Best Practice & Research in Clinical Gastroenterology, 25(1), 3\u201318.","journal-title":"Best Practice & Research in Clinical Gastroenterology"},{"key":"133_CR48","first-page":"460","volume":"10","author":"VA Nair","year":"2016","unstructured":"Nair, V. A., Beniwal-Patel, P., Mbah, I., Young, B. M., Prabhakaran, V., & Saha, S. (2016). Structural imaging changes and behavioral correlates in patients with Crohn's disease in remission. Frontiers in Human Neuroscience, 10, 460.","journal-title":"Frontiers in Human Neuroscience"},{"issue":"3","key":"133_CR49","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.pneurobio.2008.09.001","volume":"86","author":"ET Rolls","year":"2008","unstructured":"Rolls, E. T., & Grabenhorst, F. (2008). The orbitofrontal cortex and beyond: From affect to decision-making. Progress in Neurobiology, 86(3), 216\u2013244.","journal-title":"Progress in Neurobiology"},{"key":"133_CR50","doi-asserted-by":"crossref","unstructured":"Rubio, A., Van Oudenhove, L., Pellissier, S., Ly, H. G., Dupont, P., de Micheaux, H. L., et al. (2015). Uncertainty in anticipation of uncomfortable rectal distension is modulated by the autonomic nervous system \u2014 A fMRI study in healthy volunteers. Neuroimage, 107, 10\u201322.","DOI":"10.1016\/j.neuroimage.2014.11.043"},{"issue":"1","key":"133_CR51","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1053\/j.gastro.2010.03.049","volume":"139","author":"DA Seminowicz","year":"2010","unstructured":"Seminowicz, D. A., Labus, J. S., Bueller, J. A., Tillisch, K., Naliboff, B. D., Bushnell, M. C., et al. (2010). Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology, 139(1), 48\u201357.e2.","journal-title":"Gastroenterology"},{"issue":"3","key":"133_CR52","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.neuroimage.2007.03.022","volume":"36","author":"JL Stein","year":"2007","unstructured":"Stein, J. L., Wiedholz, L. M., Bassett, D. S., Weinberger, D. R., Zink, C. F., Mattay, V. S., et al. (2007). A validated network of effective amygdala connectivity. Neuroimage, 36(3), 736\u2013745.","journal-title":"Neuroimage"},{"issue":"1","key":"133_CR53","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1053\/j.gastro.2010.07.053","volume":"140","author":"K Tillisch","year":"2011","unstructured":"Tillisch, K., Mayer, E. A., & Labus, J. S. (2011). Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology, 140(1), 91\u2013100.","journal-title":"Gastroenterology"},{"issue":"1","key":"133_CR54","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/bja\/aen102","volume":"101","author":"I Tracey","year":"2008","unstructured":"Tracey, I. (2008). Imaging pain. British Journal of Anaesthesia, 101(1), 32\u201339.","journal-title":"British Journal of Anaesthesia"},{"issue":"7","key":"133_CR55","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/nrn1704","volume":"6","author":"BA Vogt","year":"2005","unstructured":"Vogt, B. A. (2005). Pain and emotion interactions in subregions of the cingulate gyrus. Nature Reviews Neuroscience, 6(7), 533\u2013544.","journal-title":"Nature Reviews Neuroscience"},{"issue":"1","key":"133_CR56","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s12876-017-0673-y","volume":"17","author":"D Wang","year":"2017","unstructured":"Wang, D., Zhang, X., Zhang, X., Huang, Z., & Song, Y. (2017). Magnetic resonance imaging analysis of brain function in patients with irritable bowel syndrome. BMC Gastroenterology, 17(1), 148.","journal-title":"BMC Gastroenterology"},{"issue":"1","key":"133_CR57","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s12883-018-1119-z","volume":"18","author":"Y Yang","year":"2018","unstructured":"Yang, Y., Wang, H., Zhou, W., Qian, T., Sun, W., & Zhao, G. (2018). Electroclinical characteristics of seizures arising from the precuneus based on stereoelectroencephalography (SEEG). BMC Neurology, 18(1), 110.","journal-title":"BMC Neurology"},{"issue":"1","key":"133_CR58","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuroimage.2004.08.027","volume":"24","author":"H Zhang","year":"2005","unstructured":"Zhang, H., Reitz, A., Kollias, S., Summers, P., Curt, A., & Schurch, B. (2005). An fMRI study of the role of suprapontine brain structures in the voluntary voiding control induced by pelvic floor contraction. Neuroimage, 24(1), 174\u2013180.","journal-title":"Neuroimage"},{"key":"133_CR59","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.neulet.2016.08.042","volume":"632","author":"Q Zhu","year":"2016","unstructured":"Zhu, Q., Cai, W., Zheng, J., Li, G., Meng, Q., Liu, Q., et al. (2016). Distinct resting-state brain activity in patients with functional constipation. Neuroscience Letters, 632, 141\u2013146.","journal-title":"Neuroscience Letters"}],"container-title":["Brain Imaging and Behavior"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11682-019-00133-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11682-019-00133-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11682-019-00133-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T08:10:38Z","timestamp":1603095038000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11682-019-00133-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,19]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["133"],"URL":"https:\/\/doi.org\/10.1007\/s11682-019-00133-4","relation":{},"ISSN":["1931-7557","1931-7565"],"issn-type":[{"value":"1931-7557","type":"print"},{"value":"1931-7565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,19]]},"assertion":[{"value":"19 June 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Informed consent was obtained from all patients included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}