{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T16:21:42Z","timestamp":1774714902617,"version":"3.50.1"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T00:00:00Z","timestamp":1587081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T00:00:00Z","timestamp":1587081600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"the Natural Scientific Foundation of China","award":["81322020 and 81230032"],"award-info":[{"award-number":["81322020 and 81230032"]}]},{"name":"the Natural Scientific Foundation of China","award":["81801686"],"award-info":[{"award-number":["81801686"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Imaging and Behavior"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s11682-019-00223-3","type":"journal-article","created":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T15:04:03Z","timestamp":1587135843000},"page":"2731-2744","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Gut dysbiosis-influence on amygdala-based functional activity in patients with end stage renal disease: a preliminary study"],"prefix":"10.1007","volume":"14","author":[{"given":"Li Juan","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhui","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhihong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Bing","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin Yuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Fei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang Ming","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dehua","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6664-7224","authenticated-orcid":false,"given":"Long Jiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,4,17]]},"reference":[{"key":"223_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fphar.2017.00370","volume":"8","author":"S Adesso","year":"2017","unstructured":"Adesso, S., Magnus, T., Cuzzocrea, S., Campolo, M., Rissiek, B., Paciello, O., Autore, G., Pinto, A., & Cooper, D. (2017). Indoxyl sulfate affects glial function increasing oxidative stress and neuroinflammation in chronic kidney disease: interaction between astrocytes and microglia. Frontiers in Pharmacology, 8, 1\u201313. https:\/\/doi.org\/10.3389\/fphar.2017.00370.","journal-title":"Frontiers in Pharmacology"},{"key":"223_CR2","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1681\/ASN.2015111285","volume":"28","author":"K Andersen","year":"2017","unstructured":"Andersen, K., Kesper, M. S., Marschner, J. A., Konrad, L., Ryu, M., Kumar, V. S., Kulkarni, O. P., Mulay, S. R., Romoli, S., Demleitner, J., Schiller, P., Dietrich, A., M\u00fcller, S., Gross, O., Ruscheweyh, H.-J., Huson, D. H., Stecher, B., & Anders, H.-J. (2017). Intestinal dysbiosis, barrier dysfunction, and bacterial translocation account for CKD\u2013related systemic inflammation. Journal of the American Society of Nephrology, 28, 76\u201383. https:\/\/doi.org\/10.1681\/ASN.2015111285.","journal-title":"Journal of the American Society of Nephrology"},{"key":"223_CR3","doi-asserted-by":"publisher","unstructured":"J. Ashburner, (2010). VBM Tutorial. https:\/\/doi.org\/10.1007\/BF01908075.","DOI":"10.1007\/BF01908075"},{"key":"223_CR4","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1097\/JGP.0b013e318211069a","volume":"19","author":"J Burke","year":"2011","unstructured":"Burke, J., McQuoid, D. R., Payne, M. E., Steffens, D. C., Krishnan, R. R., & Taylor, W. D. (2011). Amygdala volume in late-life depression: Relationship with age of onset. The American Journal of Geriatric Psychiatry, 19, 771\u2013776. https:\/\/doi.org\/10.1097\/JGP.0b013e318211069a.","journal-title":"The American Journal of Geriatric Psychiatry"},{"key":"223_CR5","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1016\/j.neubiorev.2013.07.001","volume":"37","author":"M Catani","year":"2013","unstructured":"Catani, M., Dell\u2019Acqua, F., & Thiebaut de Schotten, M. (2013). A revised limbic system model for memory, emotion and behaviour. Neuroscience and Biobehavioral Reviews, 37, 1724\u20131737. https:\/\/doi.org\/10.1016\/j.neubiorev.2013.07.001.","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"223_CR6","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1002\/gps.4686","volume":"33","author":"RA Charlton","year":"2018","unstructured":"Charlton, R. A., Lamar, M., Zhang, A., Ren, X., Ajilore, O., Pandey, G. N., & Kumar, A. (2018). Associations between pro-inflammatory cytokines, learning, and memory in late-life depression and healthy aging. International Journal of Geriatric Psychiatry, 33, 104\u2013112. https:\/\/doi.org\/10.1002\/gps.4686.","journal-title":"International Journal of Geriatric Psychiatry"},{"key":"223_CR7","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.1007\/s12035-016-9811-8","volume":"54","author":"HJ Chen","year":"2016","unstructured":"Chen, H. J., Wang, Y. F., Qi, R., & Schoepf, U. J. (2016). Altered amygdala resting-state functional connectivity in maintenance hemodialysis end-stage renal disease patients with depressive mood. Molecular Neurobiology, 54, 2223\u20132233. https:\/\/doi.org\/10.1007\/s12035-016-9811-8.","journal-title":"Molecular Neurobiology"},{"key":"223_CR8","doi-asserted-by":"publisher","first-page":"109","DOI":"10.2215\/CJN.00420117","volume":"13","author":"HJ Chen","year":"2018","unstructured":"Chen, H. J., Wen, J., Qi, R., Zhong, J., Schoepf, U. J., Varga-Szemes, A., Lesslie, V. W., Kong, X., Wang, Y. F., Xu, Q., Zhang, Z., Li, X., Lu, G. M., & Zhang, L. J. (2018). Re-establishing brain networks in patients with ESRD after successful kidney transplantation. Clinical Journal of the American Society of Nephrology, 13, 109\u2013117. https:\/\/doi.org\/10.2215\/CJN.00420117.","journal-title":"Clinical Journal of the American Society of Nephrology"},{"key":"223_CR9","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s40168-016-0195-9","volume":"4","author":"J Crespo-Salgado","year":"2016","unstructured":"Crespo-Salgado, J., Vehaskari, V. M., Stewart, T., Ferris, M., Zhang, Q., Wang, G., Blanchard, E. E., Taylor, C. M., Kallash, M., Greenbaum, L. A., & Aviles, D. H. (2016). Intestinal microbiota in pediatric patients with end stage renal disease: A Midwest pediatric nephrology consortium study. Microbiome., 4, 50. https:\/\/doi.org\/10.1186\/s40168-016-0195-9.","journal-title":"Microbiome."},{"key":"223_CR10","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1001\/jamapsychiatry.2014.1087","volume":"71","author":"KR Cullen","year":"2014","unstructured":"Cullen, K. R., Westlund, M. K., Klimes-dougan, B., Mueller, B. A., Houri, A., Eberly, L. E., & Lim, K. O. (2014). Abnormal amygdala resting-state functional connectivity in adolescent depression. JAMA Psychiatry, 71, 1138\u20131147. https:\/\/doi.org\/10.1001\/jamapsychiatry.2014.1087.","journal-title":"JAMA Psychiatry"},{"key":"223_CR11","doi-asserted-by":"publisher","unstructured":"Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008). From inflammation to sickness and depression: when the immune system subjugates the brain. Nature Reviews Neuroscience, 9, 46\u201356. https:\/\/doi.org\/10.1038\/nrn2297.","DOI":"10.1038\/nrn2297"},{"key":"223_CR12","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/j.cyto.2012.12.005","volume":"61","author":"RA de Paus","year":"2013","unstructured":"de Paus, R. A., van Wengen, A., Schmidt, I., Visser, M., Verdegaal, E. M. E., van Dissel, J. T., & van de Vosse, E. (2013). Inhibition of the type I immune responses of human monocytes by IFN-\u03b1 and IFN-\u03b2. Cytokine., 61, 645\u2013655. https:\/\/doi.org\/10.1016\/j.cyto.2012.12.005.","journal-title":"Cytokine."},{"key":"223_CR13","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.nlm.2014.08.008","volume":"115","author":"EJ Donzis","year":"2014","unstructured":"Donzis, E. J., & Tronson, N. C. (2014). Modulation of learning and memory by cytokines: Signaling mechanisms and long term consequences. Neurobiology of Learning and Memory, 115, 68\u201377. https:\/\/doi.org\/10.1016\/j.nlm.2014.08.008.","journal-title":"Neurobiology of Learning and Memory"},{"key":"223_CR14","doi-asserted-by":"publisher","unstructured":"Escolano, C., Navarro-Gil, M., Garcia-Campayo, J., Congedo, M., De Ridder, D., & Minguez, J. (2014). A controlled study on the cognitive effect of alpha neurofeedback training in patients with major depressive disorder. Frontiers in Behavioral Neuroscience, 8. https:\/\/doi.org\/10.3389\/fnbeh.2014.00296.","DOI":"10.3389\/fnbeh.2014.00296"},{"key":"223_CR15","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.ynstr.2017.03.001","volume":"7","author":"JA Foster","year":"2017","unstructured":"Foster, J. A., Rinaman, L., & Cryan, J. F. (2017). Neurobiology of stress stress & the gut-brain axis: Regulation by the microbiome. Neurobiology of Stress, 7, 124\u2013136. https:\/\/doi.org\/10.1016\/j.ynstr.2017.03.001.","journal-title":"Neurobiology of Stress"},{"key":"223_CR16","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1111\/mmi.14058","volume":"109","author":"T Franke","year":"2018","unstructured":"Franke, T., & Deppenmeier, U. (2018). Physiology and central carbon metabolism of the gut bacterium Prevotella copri. Molecular Microbiology, 109, 528\u2013540. https:\/\/doi.org\/10.1111\/mmi.14058.","journal-title":"Molecular Microbiology"},{"key":"223_CR17","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/s11894-017-0546-0","volume":"19","author":"M Garg","year":"2017","unstructured":"Garg, M., & Ooi, C. Y. (2017). The enigmatic gut in cystic fibrosis: Linking inflammation, dysbiosis, and the increased risk of malignancy. Current Gastroenterology Reports, 19, 6. https:\/\/doi.org\/10.1007\/s11894-017-0546-0.","journal-title":"Current Gastroenterology Reports"},{"key":"223_CR18","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.bbi.2015.07.007","volume":"50","author":"E Glennon","year":"2015","unstructured":"Glennon, E., Kaunzner, U. W., Gagnidze, K., McEwen, B. S., & Bulloch, K. (2015). Pituitary dendritic cells communicate immune pathogenic signals. Brain, Behavior, and Immunity, 50, 232\u2013240. https:\/\/doi.org\/10.1016\/j.bbi.2015.07.007.","journal-title":"Brain, Behavior, and Immunity"},{"key":"223_CR19","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1001\/jama.2010.619","volume":"303","author":"SS Hedayati","year":"2010","unstructured":"Hedayati, S. S., Minhajuddin, A. T., Afshar, M., Toto, R. D., Trivedi, M. H., & Rush, A. J. (2010). Association between major depressive episodes in patients with chronic kidney disease and initiation of dialysis, hospitalization, or death. JAMA., 303, 1946\u20131953. https:\/\/doi.org\/10.1001\/jama.2010.619.","journal-title":"JAMA."},{"key":"223_CR20","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1038\/ki.2011.358","volume":"81","author":"SS Hedayati","year":"2012","unstructured":"Hedayati, S. S., Yalamanchili, V., & Finkelstein, F. O. (2012). A practical approach to the treatment of depression in patients with chronic kidney disease and end-stage renal disease. Kidney International, 81, 247\u2013255. https:\/\/doi.org\/10.1038\/ki.2011.358.","journal-title":"Kidney International"},{"key":"223_CR21","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.bbi.2015.06.022","volume":"50","author":"JM Heisler","year":"2015","unstructured":"Heisler, J. M., & O\u2019Connor, J. C. (2015). Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory. Brain, Behavior, and Immunity, 50, 115\u2013124. https:\/\/doi.org\/10.1016\/j.bbi.2015.06.022.","journal-title":"Brain, Behavior, and Immunity"},{"key":"223_CR22","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1038\/nrgastro.2014.66","volume":"11","author":"C Hill","year":"2014","unstructured":"Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D. J., Pot, B., Morelli, L., Canani, R. B., Flint, H. J., Salminen, S., Calder, P. C., & Sanders, M. E. (2014). Expert consensus document: The international scientific association for probiotics and prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews Gastroenterology & Hepatology, 11, 506\u2013114. https:\/\/doi.org\/10.1038\/nrgastro.2014.66.","journal-title":"Nature Reviews Gastroenterology & Hepatology"},{"key":"223_CR23","doi-asserted-by":"publisher","first-page":"553","DOI":"10.3233\/JAD-2009-1163","volume":"18","author":"RA Honea","year":"2009","unstructured":"Honea, R. A., Vidoni, E., Harsha, A., & Burns, J. M. (2009). Impact of APOE on the healthy aging brain: A voxel-based MRI and DTI study. Journal of Alzheimer\u2019s Disease, 18, 553\u2013564. https:\/\/doi.org\/10.3233\/JAD-2009-1163.","journal-title":"Journal of Alzheimer\u2019s Disease"},{"key":"223_CR24","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.5694\/mjao12.10597","volume":"199","author":"MJ Hopwood","year":"2013","unstructured":"Hopwood, M. J. (2013). Depression and physical illness. The Medical Journal of Australia, 199, S9\u2013S12. https:\/\/doi.org\/10.5694\/mjao12.10597.","journal-title":"The Medical Journal of Australia"},{"key":"223_CR25","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1038\/nature14188","volume":"517","author":"PH Janak","year":"2015","unstructured":"Janak, P. H., & Tye, K. M. (2015). From circuits to behaviour in the amygdala. Nature, 517, 284\u2013292. https:\/\/doi.org\/10.1038\/nature14188.","journal-title":"Nature"},{"key":"223_CR26","doi-asserted-by":"publisher","unstructured":"Janik, R., Thomason, L. A. M., Stanisz, A. M., Forsythe, P., Bienenstock, J., & Stanisz, G. J. (2016). Magnetic resonance spectroscopy reveals oral Lactobacillus promotion of increases in brain GABA, N-acetyl aspartate and glutamate. Neuroimage, 125, 988\u2013995. https:\/\/doi.org\/10.1016\/j.neuroimage.2015.11.018.","DOI":"10.1016\/j.neuroimage.2015.11.018"},{"key":"223_CR27","doi-asserted-by":"publisher","unstructured":"Jiang, S., Xie, S., Lv, D., Zhang, Y., Deng, J., Zeng, L., & Chen, Y. (2016). A reduction in the butyrate producing species Roseburia spp. and Faecalibacterium prausnitzii is associated with chronic kidney disease progression. Antonie Van Leeuwenhoek, 109, 1389\u20131396. https:\/\/doi.org\/10.1007\/s10482-016-0737-y.","DOI":"10.1007\/s10482-016-0737-y"},{"key":"223_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-02989-2","volume":"7","author":"S Jiang","year":"2017","unstructured":"Jiang, S., Xie, S., Lv, D., Wang, P., He, H., Zhang, T., Lin, Q., Zhou, H., Jiang, J., Nie, J., Hou, F., & Chen, Y. (2017a). Alteration of the gut microbiota in Chinese population with chronic kidney disease. Scientific Reports, 7, 1\u201310. https:\/\/doi.org\/10.1038\/s41598-017-02989-2.","journal-title":"Scientific Reports"},{"key":"223_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3233\/JAD-161141","volume":"58","author":"C Jiang","year":"2017","unstructured":"Jiang, C., Li, G., Huang, P., Liu, Z., & Zhao, B. (2017b). The gut microbiota and Alzheimer\u2019s disease. Journal of Alzheimer\u2019s Disease, 58, 1\u201315. https:\/\/doi.org\/10.3233\/JAD-161141.","journal-title":"Journal of Alzheimer\u2019s Disease"},{"key":"223_CR30","doi-asserted-by":"publisher","unstructured":"Kim, Y. K., Amidfar, M., & Won, E. (2019). A review on inflammatory cytokine-induced alterations of the brain as potential neural biomarkers in posttraumatic stress disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 91, 103\u2013112. https:\/\/doi.org\/10.1016\/j.pnpbp.2018.06.008.","DOI":"10.1016\/j.pnpbp.2018.06.008"},{"key":"223_CR31","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1053\/j.ajkd.2004.08.044","volume":"45","author":"M Kurella","year":"2005","unstructured":"Kurella, M., Yaffe, K., Shlipak, M. G., Wenger, N. K., & Chertow, G. M. (2005). Chronic kidney disease and cognitive impairment in menopausal women. American Journal of Kidney Diseases, 45, 66\u201376. https:\/\/doi.org\/10.1053\/j.ajkd.2004.08.044.","journal-title":"American Journal of Kidney Diseases"},{"key":"223_CR32","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/nrgastro.2016.4","volume":"13","author":"RE Ley","year":"2016","unstructured":"Ley, R. E. (2016). Gut microbiota in 2015: Prevotella in the gut: Choose carefully. Nature Reviews. Gastroenterology & Hepatology, 13, 69\u201370. https:\/\/doi.org\/10.1038\/nrgastro.2016.4.","journal-title":"Nature Reviews. Gastroenterology & Hepatology"},{"key":"223_CR33","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1007\/s11011-018-0254-y","volume":"33","author":"A Li","year":"2018","unstructured":"Li, A., Mu, J., Huang, M., Zhang, Z., Liu, J., & Zhang, M. (2018). Altered amygdala-related structural covariance and resting-state functional connectivity in end-stage renal disease patients. Metabolic Brain Disease, 33, 1471\u20131481. https:\/\/doi.org\/10.1007\/s11011-018-0254-y.","journal-title":"Metabolic Brain Disease"},{"key":"223_CR34","doi-asserted-by":"publisher","first-page":"30673","DOI":"10.1038\/srep30673","volume":"6","author":"Z Ling","year":"2016","unstructured":"Ling, Z., Jin, C., Xie, T., Cheng, Y., Li, L., & Wu, N. (2016). Alterations in the fecal microbiota of patients with HIV-1 infection: An observational study in a Chinese population. Scientific Reports, 6, 30673. https:\/\/doi.org\/10.1038\/srep30673.","journal-title":"Scientific Reports"},{"key":"223_CR35","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1016\/S1053-8119(03)00169-1","volume":"19","author":"JA Maldjian","year":"2003","unstructured":"Maldjian, J. A., Laurienti, P. J., Kraft, R. A., & Burdette, J. H. (2003). An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage, 19, 1233\u20131239. https:\/\/doi.org\/10.1016\/S1053-8119(03)00169-1.","journal-title":"Neuroimage"},{"key":"223_CR36","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1097\/WNN.0000000000000142","volume":"30","author":"A Ma\u0144kowska","year":"2017","unstructured":"Ma\u0144kowska, A., Heilman, K. M., Williamson, J. B., Biedunkiewicz, B., D\u0229bska-\u015alizie\u0144, A., & Harciarek, M. (2017). Leftward bias of visual attention in patients with end-stage renal disease receiving dialysis: A neglected phenomenon. Cognitive and Behavioral Neurology, 30, 176\u2013181. https:\/\/doi.org\/10.1097\/WNN.0000000000000142.","journal-title":"Cognitive and Behavioral Neurology"},{"key":"223_CR37","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1016\/j.sbspro.2011.10.353","volume":"30","author":"A Marvi","year":"2011","unstructured":"Marvi, A., Bayazi, M. H., Rahmani, M., & Deloei, A. K. (2011). Studying the effect of cognitive behavioral group training on depression in hemodialysis patients. Procedia \u2013 Social and Behavioral Sciences, 30, 1831\u20131836. https:\/\/doi.org\/10.1016\/j.sbspro.2011.10.353.","journal-title":"Procedia \u2013 Social and Behavioral Sciences"},{"key":"223_CR38","doi-asserted-by":"publisher","first-page":"133","DOI":"10.2215\/CJN.04610510","volume":"6","author":"CW McIntyre","year":"2011","unstructured":"McIntyre, C. W., Harrison, L. E. A., Eldehni, M. T., Jefferies, H. J., Szeto, C.-C., John, S. G., Sigrist, M. K., Burton, J. O., Hothi, D., Korsheed, S., Owen, P. J., Lai, K.-B., & Li, P. K. T. (2011). Circulating endotoxemia: A novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease. Clinical Journal of the American Society of Nephrology, 6, 133\u2013141. https:\/\/doi.org\/10.2215\/CJN.04610510.","journal-title":"Clinical Journal of the American Society of Nephrology"},{"key":"223_CR39","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.1007\/s00467-015-3159-6","volume":"30","author":"JM Moreira","year":"2015","unstructured":"Moreira, J. M., Bouissou Morais Soares, C. M., Teixeira, A. L., Sim\u00f5es E Silva, A. C., & Kummer, A. M. (2015). Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease. Pediatric Nephrology, 30, 2153\u20132162. https:\/\/doi.org\/10.1007\/s00467-015-3159-6.","journal-title":"Pediatric Nephrology"},{"key":"223_CR40","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1007\/s11682-017-9782-z","volume":"12","author":"J Mu","year":"2018","unstructured":"Mu, J., Chen, T., Liu, Q., Ding, D., Ma, X., Li, P., Li, A., Huang, M., Zhang, Z., Liu, J., & Zhang, M. (2018). Abnormal interaction between cognitive control network and affective network in patients with end-stage renal disease. Brain Imaging and Behavior, 12, 1099\u20131111. https:\/\/doi.org\/10.1007\/s11682-017-9782-z.","journal-title":"Brain Imaging and Behavior"},{"key":"223_CR41","doi-asserted-by":"publisher","first-page":"268","DOI":"10.3389\/fnhum.2013.00268","volume":"7","author":"VI M\u00fcller","year":"2013","unstructured":"M\u00fcller, V. I., Cieslik, E. C., Laird, A. R., Fox, P. T., & Eickhoff, S. B. (2013). Dysregulated left inferior parietal activity in schizophrenia and depression: Functional connectivity and characterization. Frontiers in Human Neuroscience, 7, 268. https:\/\/doi.org\/10.3389\/fnhum.2013.00268.","journal-title":"Frontiers in Human Neuroscience"},{"key":"223_CR42","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.neuroscience.2018.08.017","volume":"390","author":"S Munshi","year":"2018","unstructured":"Munshi, S., & Rosenkranz, J. A. (2018). Effects of peripheral immune challenge on in vivo firing of Basolateral amygdala neurons in adult male rats. Neuroscience, 390, 174\u2013186. https:\/\/doi.org\/10.1016\/j.neuroscience.2018.08.017.","journal-title":"Neuroscience"},{"key":"223_CR43","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1038\/sj.mp.4002148","volume":"14","author":"JC O\u2019Connor","year":"2009","unstructured":"O\u2019Connor, J. C., Lawson, M. A., Andr\u00e9, C., Moreau, M., Lestage, J., Castanon, N., Kelley, K. W., & Dantzer, R. (2009). Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. Molecular Psychiatry, 14, 511\u2013522. https:\/\/doi.org\/10.1038\/sj.mp.4002148.","journal-title":"Molecular Psychiatry"},{"key":"223_CR44","doi-asserted-by":"publisher","unstructured":"Palmer, S., Vecchio, M., Craig, J. C., Tonelli, M., Johnson, D. W., Nicolucci, A., Pellegrini, F., Saglimbene, V., Logroscino, G., Fishbane, S., & Strippoli, G. F. M. (2013). Prevalence of depression in chronic kidney disease: Systematic review and meta-analysis of observational studies. Kidney International, 1\u201313. https:\/\/doi.org\/10.1038\/ki.2013.77.","DOI":"10.1038\/ki.2013.77"},{"key":"223_CR45","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s11255-017-1689-5","volume":"50","author":"W Pan","year":"2017","unstructured":"Pan, W., & Kang, Y. (2017). Gut microbiota and chronic kidney disease: Implications for novel mechanistic insights and therapeutic strategies. International Urology and Nephrology, 50, 289\u2013299. https:\/\/doi.org\/10.1007\/s11255-017-1689-5.","journal-title":"International Urology and Nephrology"},{"key":"223_CR46","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1681\/ASN.2013080905","volume":"25","author":"A Ramezani","year":"2014","unstructured":"Ramezani, A., & Raj, D. S. (2014). The gut microbiome, kidney disease, and targeted interventions. Journal of the American Society of Nephrology, 25, 657\u2013670. https:\/\/doi.org\/10.1681\/ASN.2013080905.","journal-title":"Journal of the American Society of Nephrology"},{"key":"223_CR47","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1038\/s41581-018-0018-2","volume":"14","author":"EM Richards","year":"2018","unstructured":"Richards, E. M., & Pepine, C. J. (2018). The gut microbiota and the brain\u2013gut\u2013kidney axis in hypertension and chronic kidney disease. Nature Reviews. Nephrology, 14, 442\u2013456. https:\/\/doi.org\/10.1038\/s41581-018-0018-2.","journal-title":"Nature Reviews. Nephrology"},{"key":"223_CR48","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.cortex.2013.12.005","volume":"62","author":"ET Rolls","year":"2015","unstructured":"Rolls, E. T. (2015). Limbic systems for emotion and for memory, but no single limbic system. Cortex., 62, 119\u2013157. https:\/\/doi.org\/10.1016\/j.cortex.2013.12.005.","journal-title":"Cortex."},{"key":"223_CR49","doi-asserted-by":"publisher","unstructured":"Schachter, J., Martel, J., Lin, C., Chang, C., Wu, T., Lu, C., Ko, Y., Lai, H., Ojcius, D. M., & Young, J. D. (2017). Effects of obesity on depression: A role for inflammation and the gut microbiota. Brain, Behavior, and Immunity. https:\/\/doi.org\/10.1016\/j.bbi.2017.08.026.","DOI":"10.1016\/j.bbi.2017.08.026"},{"key":"223_CR50","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.01202","volume":"2","author":"JU Scher","year":"2013","unstructured":"Scher, J. U., Sczesnak, A., Longman, R. S., Segata, N., Ubeda, C., Bielski, C., Rostron, T., Cerundolo, V., Pamer, E. G., Abramson, S. B., Huttenhower, C., & Littman, D. R. (2013). Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife, 2, e01202. https:\/\/doi.org\/10.7554\/eLife.01202.","journal-title":"Elife"},{"key":"223_CR51","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1093\/occmed\/kqv043","volume":"65","author":"R Sharp","year":"2015","unstructured":"Sharp, R. (2015). The hamilton rating scale for depression. Occupational Medicine (Chicago), 65, 340. https:\/\/doi.org\/10.1093\/occmed\/kqv043.","journal-title":"Occupational Medicine (Chicago)"},{"key":"223_CR52","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1007\/s12640-016-9691-8","volume":"31","author":"LC Souza","year":"2017","unstructured":"Souza, L. C., Jesse, C. R., de Gomes, M. G., Viana, C. E., Mattos, E., Silva, N. C., & Boeira, S. P. (2017). Intracerebroventricular administration of streptozotocin as an experimental approach to depression: Evidence for the involvement of proinflammatory cytokines and indoleamine-2,3-dioxygenase. Neurotoxicity Research, 31, 464\u2013477. https:\/\/doi.org\/10.1007\/s12640-016-9691-8.","journal-title":"Neurotoxicity Research"},{"key":"223_CR53","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1136\/gutjnl-2017-314759","volume":"67","author":"BR Stevens","year":"2018","unstructured":"Stevens, B. R., Goel, R., Seungbum, K., Richards, E. M., Holbert, R. C., Pepine, C. J., & Raizada, M. K. (2018). Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression. Gut, 67, 1555\u20131557. https:\/\/doi.org\/10.1136\/gutjnl-2017-314759.","journal-title":"Gut"},{"key":"223_CR54","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.bbi.2015.07.009","volume":"50","author":"RM Stilling","year":"2015","unstructured":"Stilling, R. M., Ryan, F. J., Hoban, A. E., Shanahan, F., Clarke, G., Claesson, M. J., Dinan, T. G., & Cryan, J. F. (2015). Microbes & neurodevelopment - absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala. Brain, Behavior, and Immunity, 50, 209\u2013220. https:\/\/doi.org\/10.1016\/j.bbi.2015.07.009.","journal-title":"Brain, Behavior, and Immunity"},{"key":"223_CR55","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.jneuroim.2007.05.003","volume":"188","author":"K Strle","year":"2007","unstructured":"Strle, K., McCusker, R. H., Tran, L., King, A., Johnson, R. W., Freund, G. G., Dantzer, R., & Kelley, K. W. (2007). Novel activity of an anti-inflammatory cytokine: IL-10 prevents TNF\u03b1-induced resistance to IGF-I in myoblasts. Journal of Neuroimmunology, 188, 48\u201355. https:\/\/doi.org\/10.1016\/j.jneuroim.2007.05.003.","journal-title":"Journal of Neuroimmunology"},{"key":"223_CR56","doi-asserted-by":"publisher","unstructured":"Ventura, J., Subotnik, K. L., Ered, A., Gretchen-Doorly, D., Hellemann, G. S., Vaskinn, A., & Nuechterlein, K. H. (2014). The relationship of attitudinal beliefs to negative symptoms, neurocognition, and daily functioning in recent-onset schizophrenia. Schizophrenia Bulletin. https:\/\/doi.org\/10.1093\/schbul\/sbu002.","DOI":"10.1093\/schbul\/sbu002"},{"key":"223_CR57","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s12021-016-9299-4","volume":"14","author":"CG Yan","year":"2016","unstructured":"Yan, C. G., Di Wang, X., Zuo, X. N., & Zang, Y. F. (2016). DPABI: Data Processing & Analysis for (resting-state) brain imaging. Neuroinformatics, 14, 339\u2013351. https:\/\/doi.org\/10.1007\/s12021-016-9299-4.","journal-title":"Neuroinformatics"},{"key":"223_CR58","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.jad.2017.11.026","volume":"227","author":"H Zheng","year":"2018","unstructured":"Zheng, H., Li, F., Bo, Q., Li, X., Yao, L., Yao, Z., Wang, C., & Wu, X. (2018). The dynamic characteristics of the anterior cingulate cortex in resting-state fMRI of patients with depression. Journal of Affective Disorders, 227, 391\u2013397. https:\/\/doi.org\/10.1016\/j.jad.2017.11.026.","journal-title":"Journal of Affective Disorders"}],"container-title":["Brain Imaging and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11682-019-00223-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11682-019-00223-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11682-019-00223-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T00:28:31Z","timestamp":1618619311000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11682-019-00223-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,17]]},"references-count":58,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["223"],"URL":"https:\/\/doi.org\/10.1007\/s11682-019-00223-3","relation":{},"ISSN":["1931-7557","1931-7565"],"issn-type":[{"value":"1931-7557","type":"print"},{"value":"1931-7565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,17]]},"assertion":[{"value":"17 April 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All procedures followed the tenets of the Declaration of Helsinki and were approved by the Ethics Committee of Jinling Hospital, Medical School of Nanjing University with written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}