{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:21:32Z","timestamp":1789147292630,"version":"build-2803163510"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["52227814"],"award-info":[{"award-number":["52227814"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82202099"],"award-info":[{"award-number":["82202099"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100009331","name":"Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support","doi-asserted-by":"publisher","award":["ZYLX201824"],"award-info":[{"award-number":["ZYLX201824"]}],"id":[{"id":"10.13039\/501100009331","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beijing Municipal Administration of Hospital\u2019s Mission Plan","award":["SML20150101"],"award-info":[{"award-number":["SML20150101"]}]},{"name":"Beijing Scholar 2015","award":["Zhenchang Wang"],"award-info":[{"award-number":["Zhenchang Wang"]}]},{"DOI":"10.13039\/501100019398","name":"Beijing Friendship Hospital, Capital Medical University","doi-asserted-by":"publisher","award":["seed project YYZZ202129"],"award-info":[{"award-number":["seed project YYZZ202129"]}],"id":[{"id":"10.13039\/501100019398","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Training Fund for Open Projects at Clinical Institutes and Departments of Capital Medical University","award":["CCMU2022ZKYXY011"],"award-info":[{"award-number":["CCMU2022ZKYXY011"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Imaging and Behavior"],"DOI":"10.1007\/s11682-026-01161-7","type":"journal-article","created":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T02:12:37Z","timestamp":1778292757000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Neurovascular decoupling is associated with altered glymphatic function as assessed by the DTI-ALPS index in patients on dialysis"],"prefix":"10.1007","volume":"20","author":[{"given":"Wenbo","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenghan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiantian","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weikang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Chang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,9]]},"reference":[{"issue":"6","key":"1161_CR40","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1681\/ASN.0000000000000105","volume":"34","author":"UC Anazodo","year":"2023","unstructured":"Anazodo, U. C., Wong, D. Y., Theberge, J., et al. (2023). Hemodialysis-related acute brain injury demonstrated by application of intradialytic magnetic resonance imaging and spectroscopy. Journal of the American Society of Nephrology\u202f: JASN, 34(6), 1090\u20131104. https:\/\/doi.org\/10.1681\/ASN.0000000000000105","journal-title":"Journal of the American Society of Nephrology : JASN"},{"issue":"1","key":"1161_CR20","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.neuroimage.2007.07.007","volume":"38","author":"J Ashburner","year":"2007","unstructured":"Ashburner, J. (2007). A fast diffeomorphic image registration algorithm. NeuroImage, 38(1), 95\u2013113. https:\/\/doi.org\/10.1016\/j.neuroimage.2007.07.007","journal-title":"NeuroImage"},{"issue":"7321","key":"1161_CR24","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/nature09613","volume":"468","author":"D Attwell","year":"2010","unstructured":"Attwell, D., Buchan, A. M., Charpak, S., Lauritzen, M., Macvicar, B. A., & Newman, E. A. (2010). Glial and neuronal control of brain blood flow. Nature, 468(7321), 232\u201343. https:\/\/doi.org\/10.1038\/nature09613","journal-title":"Nature"},{"key":"1161_CR7","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.976340","volume":"14","author":"A Canna","year":"2022","unstructured":"Canna, A., Esposito, F., Tedeschi, G., et al. (2022). Neurovascular coupling in patients with type 2 diabetes mellitus. Frontiers in Aging Neuroscience, 14, Article 976340. https:\/\/doi.org\/10.3389\/fnagi.2022.976340","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"10","key":"1161_CR4","doi-asserted-by":"publisher","first-page":"3691","DOI":"10.1111\/jan.15746","volume":"79","author":"T Cao","year":"2023","unstructured":"Cao, T., An, R., Wang, Y., Lei, J., Liang, J., & Wan, Q. (2023). Risk factors and prevalence of cognitive impairment in maintenance haemodialysis patients: A systematic review and meta-analysis of observational studies. J Adv Nurs Oct, 79(10), 3691\u20133706. https:\/\/doi.org\/10.1111\/jan.15746","journal-title":"J Adv Nurs Oct"},{"issue":"10225","key":"1161_CR1","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","volume":"395","author":"Collaboration GBDCKD","year":"2020","unstructured":"Collaboration GBDCKD. (2020). Global, regional, and national burden of chronic kidney disease, 1990\u20132017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 395(10225), 709\u2013733. https:\/\/doi.org\/10.1016\/S0140-6736(20)30045-3","journal-title":"Lancet"},{"issue":"10","key":"1161_CR47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0205276","volume":"13","author":"AK Diem","year":"2018","unstructured":"Diem, A. K., Carare, R. O., Weller, R. O., & Bressloff, N. W. (2018). A control mechanism for intra-mural peri-arterial drainage via astrocytes: How neuronal activity could improve waste clearance from the brain. PLoS One, 13(10), Article e0205276. https:\/\/doi.org\/10.1371\/journal.pone.0205276","journal-title":"PLoS One"},{"issue":"5","key":"1161_CR3","doi-asserted-by":"publisher","first-page":"e307","DOI":"10.1016\/S2214-109X(16)00071-1","volume":"4","author":"B Ene-Iordache","year":"2016","unstructured":"Ene-Iordache, B., Perico, N., Bikbov, B., et al. (2016). Chronic kidney disease and cardiovascular risk in six regions of the world (ISN-KDDC): A cross-sectional study. Lancet Glob Health May, 4(5), e307\u2013e319. https:\/\/doi.org\/10.1016\/S2214-109X(16)00071-1","journal-title":"Lancet Glob Health May"},{"key":"1161_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2023.106462","volume":"187","author":"Q Faucher","year":"2023","unstructured":"Faucher, Q., van der Made, T. K., De Lange, E., & Masereeuw, R. (2023). Blood-brain barrier perturbations by uremic toxins: Key contributors in chronic kidney disease-induced neurological disorders? European Journal of Pharmaceutical Sciences, 187, Article 106462. https:\/\/doi.org\/10.1016\/j.ejps.2023.106462","journal-title":"European Journal of Pharmaceutical Sciences"},{"issue":"1","key":"1161_CR31","doi-asserted-by":"publisher","first-page":"167","DOI":"10.12669\/pjms.38.1.4281","volume":"38","author":"EM Fazl","year":"2022","unstructured":"Fazl, E. M., Ahmad, S., Elahi, I., & Anees, M. (2022). Comparison between different methods of calculating Kt\/V as the marker of adequacy of dialysis. Pak J Med Sci Jan-Feb, 38(1), 167\u2013171. https:\/\/doi.org\/10.12669\/pjms.38.1.4281","journal-title":"Pak J Med Sci Jan-Feb"},{"issue":"3","key":"1161_CR19","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/mrm.1910350312","volume":"35","author":"KJ Friston","year":"1996","unstructured":"Friston, K. J., Williams, S., Howard, R., Frackowiak, R. S., & Turner, R. (1996). Movement-related effects in fMRI time-series. Magnetic Resonance in Medicine, 35(3), 346\u201355. https:\/\/doi.org\/10.1002\/mrm.1910350312","journal-title":"Magnetic Resonance in Medicine"},{"issue":"6465","key":"1161_CR46","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1126\/science.aax5440","volume":"366","author":"NE Fultz","year":"2019","unstructured":"Fultz, N. E., Bonmassar, G., Setsompop, K., et al. (2019). Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep. Science, 366(6465), 628\u2013631. https:\/\/doi.org\/10.1126\/science.aax5440","journal-title":"Science"},{"key":"1161_CR16","doi-asserted-by":"publisher","first-page":"976089","DOI":"10.3389\/fneur.2022.976089","volume":"13","author":"CM Heo","year":"2022","unstructured":"Heo, C. M., Lee, D. A., Park, K. M., et al. (2022). Glymphatic system dysfunction in patients with early chronic kidney disease. Frontiers In Neurology, 13, 976089. https:\/\/doi.org\/10.3389\/fneur.2022.976089","journal-title":"Frontiers In Neurology"},{"key":"1161_CR35","doi-asserted-by":"publisher","first-page":"809438","DOI":"10.3389\/fneur.2021.809438","volume":"12","author":"CM Heo","year":"2021","unstructured":"Heo, C. M., Lee, W. H., Park, B. S., et al. (2021). Glymphatic Dysfunction in Patients With End-Stage Renal Disease. Frontiers In Neurology, 12, 809438. https:\/\/doi.org\/10.3389\/fneur.2021.809438","journal-title":"Frontiers In Neurology"},{"issue":"4","key":"1161_CR43","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1002\/ana.26729","volume":"94","author":"P He","year":"2023","unstructured":"He, P., Shi, L., Li, Y., et al. (2023). The association of the glymphatic function with Parkinson\u2019s disease symptoms: Neuroimaging evidence from longitudinal and cross-sectional studies. Annals of Neurology, 94(4), 672\u2013683. https:\/\/doi.org\/10.1002\/ana.26729","journal-title":"Annals of Neurology"},{"issue":"6","key":"1161_CR18","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1038\/s41593-023-01327-2","volume":"26","author":"S Holstein-Ronsbo","year":"2023","unstructured":"Holstein-Ronsbo, S., Gan, Y., Giannetto, M. J., et al. (2023). Glymphatic influx and clearance are accelerated by neurovascular coupling. Nat Neurosci Jun, 26(6), 1042\u20131053. https:\/\/doi.org\/10.1038\/s41593-023-01327-2","journal-title":"Nat Neurosci Jun"},{"issue":"1","key":"1161_CR41","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1002\/ana.26516","volume":"93","author":"JL Hsu","year":"2023","unstructured":"Hsu, J. L., Wei, Y. C., Toh, C. H., et al. (2023). Magnetic resonance images implicate that glymphatic alterations mediate cognitive dysfunction in Alzheimer disease. Annals of Neurology, 93(1), 164\u2013174. https:\/\/doi.org\/10.1002\/ana.26516","journal-title":"Annals of Neurology"},{"issue":"147","key":"1161_CR12","doi-asserted-by":"publisher","first-page":"147ra111","DOI":"10.1126\/scitranslmed.3003748","volume":"15","author":"JJ Iliff","year":"2012","unstructured":"Iliff, J. J., Wang, M., Liao, Y., et al. (2012). A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Sci Transl Med Aug, 15(147), 147ra111. https:\/\/doi.org\/10.1126\/scitranslmed.3003748","journal-title":"Sci Transl Med Aug"},{"key":"1161_CR10","doi-asserted-by":"publisher","first-page":"e8989","DOI":"10.7717\/peerj.8989","volume":"8","author":"M Jin","year":"2020","unstructured":"Jin, M., Wang, L., Wang, H., et al. (2020). Disturbed neurovascular coupling in hemodialysis patients. PeerJ, 8, e8989. https:\/\/doi.org\/10.7717\/peerj.8989","journal-title":"PeerJ"},{"issue":"12","key":"1161_CR28","doi-asserted-by":"publisher","first-page":"2071","DOI":"10.1681\/ASN.2013030314","volume":"24","author":"M Lambie","year":"2013","unstructured":"Lambie, M., Chess, J., Donovan, K. L., et al. (2013). Independent effects of systemic and peritoneal inflammation on peritoneal dialysis survival. Journal of the American Society of Nephrology, 24(12), 2071\u201380. https:\/\/doi.org\/10.1681\/ASN.2013030314","journal-title":"Journal of the American Society of Nephrology"},{"issue":"2","key":"1161_CR17","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2023.2265665","volume":"45","author":"YJ Lee","year":"2023","unstructured":"Lee, Y. J., Park, K. M., Heo, C. M., et al. (2023). Changes in the glymphatic system before and after dialysis initiation in patients with end-stage kidney disease. Renal Failure, 45(2), Article 2265665. https:\/\/doi.org\/10.1080\/0886022X.2023.2265665","journal-title":"Renal Failure"},{"issue":"5","key":"1161_CR22","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1073\/pnas.1214900110","volume":"29","author":"X Liang","year":"2013","unstructured":"Liang, X., Zou, Q., He, Y., & Yang, Y. (2013). Coupling of functional connectivity and regional cerebral blood flow reveals a physiological basis for network hubs of the human brain. Proc Natl Acad Sci U S A Jan, 29(5), 1929\u20131934. https:\/\/doi.org\/10.1073\/pnas.1214900110","journal-title":"Proc Natl Acad Sci U S A Jan"},{"key":"1161_CR48","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00869","volume":"13","author":"C Li","year":"2019","unstructured":"Li, C., Wu, X., Liu, S., Zhao, Y., Zhu, J., & Liu, K. (2019). Roles of neuropeptide Y in neurodegenerative and neuroimmune diseases. Frontiers in Neuroscience, 13, Article 869. https:\/\/doi.org\/10.3389\/fnins.2019.00869","journal-title":"Frontiers in Neuroscience"},{"issue":"3","key":"1161_CR11","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1002\/hbm.26122","volume":"15","author":"P Li","year":"2023","unstructured":"Li, P., Ma, S., Ma, X., et al. (2023). Reversal of neurovascular decoupling and cognitive impairment in patients with end-stage renal disease during a hemodialysis session: Evidence from a comprehensive fMRI analysis. Hum Brain Mapp Feb, 15(3), 989\u20131001. https:\/\/doi.org\/10.1002\/hbm.26122","journal-title":"Hum Brain Mapp Feb"},{"issue":"10","key":"1161_CR9","doi-asserted-by":"publisher","first-page":"2593","DOI":"10.1177\/0271678X211007960","volume":"41","author":"P Li","year":"2021","unstructured":"Li, P., Mu, J., Ma, X., et al. (2021). Neurovascular coupling dysfunction in end-stage renal disease patients related to cognitive impairment. Journal of Cerebral Blood Flow & Metabolism, 41(10), 2593\u20132606. https:\/\/doi.org\/10.1177\/0271678X211007960","journal-title":"Journal of Cerebral Blood Flow & Metabolism"},{"issue":"6","key":"1161_CR42","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1002\/ana.26911","volume":"95","author":"M Margoni","year":"2024","unstructured":"Margoni, M., Pagani, E., Meani, A., et al. (2024). Cognitive Impairment Is Related to Glymphatic System Dysfunction in Pediatric Multiple Sclerosis. Ann Neurol Jun, 95(6), 1080\u20131092. https:\/\/doi.org\/10.1002\/ana.26911","journal-title":"Ann Neurol Jun"},{"issue":"11","key":"1161_CR32","doi-asserted-by":"publisher","first-page":"3469","DOI":"10.1681\/ASN.2015091035","volume":"27","author":"TW Meyer","year":"2016","unstructured":"Meyer, T. W., Sirich, T. L., Fong, K. D., et al. (2016). Kt\/Vurea and nonurea small solute levels in the Hemodialysis Study. Journal of the American Society of Nephrology, 27(11), 3469\u20133478. https:\/\/doi.org\/10.1681\/ASN.2015091035","journal-title":"Journal of the American Society of Nephrology"},{"issue":"4","key":"1161_CR23","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1111\/apha.12250","volume":"210","author":"V Muoio","year":"2014","unstructured":"Muoio, V., Persson, P. B., & Sendeski, M. M. (2014). The neurovascular unit - Concept review. Acta Physiologica (Oxford, England), 210(4), 790\u20138. https:\/\/doi.org\/10.1111\/apha.12250","journal-title":"Acta Physiologica (Oxford, England)"},{"key":"1161_CR30","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.neuint.2019.03.011","volume":"126","author":"M Naveed","year":"2019","unstructured":"Naveed, M., Zhou, Q. G., & Han, F. (2019). Cerebrovascular inflammation: A critical trigger for neurovascular injury? Neurochem Int Jun, 126, 165\u2013177. https:\/\/doi.org\/10.1016\/j.neuint.2019.03.011","journal-title":"Neurochem Int Jun"},{"key":"1161_CR26","doi-asserted-by":"publisher","unstructured":"Owens, C. D., Pinto, C. B., Mukli, P., et al. (2024). Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment. Alzheimers Dement Jul, 3. https:\/\/doi.org\/10.1002\/alz.14072","DOI":"10.1002\/alz.14072"},{"issue":"1","key":"1161_CR29","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1053\/j.ajkd.2019.09.016","volume":"76","author":"J Perl","year":"2020","unstructured":"Perl, J., Fuller, D. S., Bieber, B. A., et al. (2020). Peritoneal dialysis-related infection rates and outcomes: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS). American Journal of Kidney Diseases, 76(1), 42\u201353. https:\/\/doi.org\/10.1053\/j.ajkd.2019.09.016","journal-title":"American Journal of Kidney Diseases"},{"issue":"4","key":"1161_CR6","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1177\/0271678X15617954","volume":"36","author":"AA Phillips","year":"2016","unstructured":"Phillips, A. A., Chan, F. H., Zheng, M. M., Krassioukov, A. V., & Ainslie, P. N. (2016). Neurovascular coupling in humans: Physiology, methodological advances and clinical implications. J Cereb Blood Flow Metab Apr, 36(4), 647\u2013664. https:\/\/doi.org\/10.1177\/0271678X15617954","journal-title":"J Cereb Blood Flow Metab Apr"},{"key":"1161_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22126196","author":"A Pieniazek","year":"2021","unstructured":"Pieniazek, A., Bernasinska-Slomczewska, J., & Gwozdzinski, L. (2021). Uremic toxins and their relation with oxidative stress induced in patients with CKD. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms22126196","journal-title":"International Journal of Molecular Sciences"},{"issue":"11","key":"1161_CR45","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1016\/S1474-4422(18)30318-1","volume":"17","author":"MK Rasmussen","year":"2018","unstructured":"Rasmussen, M. K., Mestre, H., & Nedergaard, M. (2018). The glymphatic pathway in neurological disorders. The Lancet. Neurology, 17(11), 1016\u20131024. https:\/\/doi.org\/10.1016\/S1474-4422(18)30318-1","journal-title":"The Lancet. Neurology"},{"key":"1161_CR14","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232112928","author":"A Scott-Massey","year":"2022","unstructured":"Scott-Massey, A., Boag, M. K., Magnier, A., Bispo, D., Khoo, T. K., & Pountney, D. L. (2022). Glymphatic system dysfunction and sleep disturbance may contribute to the pathogenesis and progression of Parkinson\u2019s Disease. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms232112928","journal-title":"International Journal of Molecular Sciences"},{"issue":"1","key":"1161_CR25","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12868-018-0465-5","volume":"17","author":"O Shabir","year":"2018","unstructured":"Shabir, O., Berwick, J., & Francis, S. E. (2018). Neurovascular dysfunction in vascular dementia, Alzheimer\u2019s and atherosclerosis. BMC Neurosci Oct, 17(1), 62. https:\/\/doi.org\/10.1186\/s12868-018-0465-5","journal-title":"BMC Neurosci Oct"},{"issue":"9","key":"1161_CR8","doi-asserted-by":"publisher","first-page":"1719","DOI":"10.1177\/0271678X221098503","volume":"42","author":"S Shang","year":"2022","unstructured":"Shang, S., Ye, J., Wu, J., et al. (2022). Early disturbance of dynamic synchronization and neurovascular coupling in cognitively normal Parkinson\u2019s disease. J Cereb Blood Flow Metab Sep, 42(9), 1719\u20131731. https:\/\/doi.org\/10.1177\/0271678X221098503","journal-title":"J Cereb Blood Flow Metab Sep"},{"issue":"4","key":"1161_CR15","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1007\/s11604-017-0617-z","volume":"35","author":"T Taoka","year":"2017","unstructured":"Taoka, T., Masutani, Y., Kawai, H., et al. (2017). Evaluation of glymphatic system activity with the diffusion MR technique: Diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer\u2019s disease cases. Japanese Journal of Radiology, 35(4), 172\u2013178. https:\/\/doi.org\/10.1007\/s11604-017-0617-z","journal-title":"Japanese Journal of Radiology"},{"issue":"1","key":"1161_CR34","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1002\/jmri.26892","volume":"51","author":"T Taoka","year":"2020","unstructured":"Taoka, T., & Naganawa, S. (2020). Glymphatic imaging using MRI. J Magn Reson Imaging Jan, 51(1), 11\u201324. https:\/\/doi.org\/10.1002\/jmri.26892","journal-title":"J Magn Reson Imaging Jan"},{"issue":"11","key":"1161_CR33","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1080\/14737159.2021.1987216","volume":"21","author":"M Torreggiani","year":"2021","unstructured":"Torreggiani, M., Fois, A., Njandjo, L., et al. (2021). Toward an individualized determination of dialysis adequacy: A narrative review with special emphasis on incremental hemodialysis. Expert Review of Molecular Diagnostics, 21(11), 1119\u20131137. https:\/\/doi.org\/10.1080\/14737159.2021.1987216","journal-title":"Expert Review of Molecular Diagnostics"},{"issue":"2","key":"1161_CR27","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1177\/089686080802800209","volume":"28","author":"F Verbeke","year":"2008","unstructured":"Verbeke, F., Van Biesen, W., Pletinck, A., Van Bortel, L. M., & Vanholder, R. (2008). Acute central hemodynamic effects of a volume exchange in peritoneal dialysis. Peritoneal Dialysis International\u202f: Journal of the International Society for Peritoneal Dialysis, 28(2), 142\u20138.","journal-title":"Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis"},{"issue":"2","key":"1161_CR49","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1159\/000489145","volume":"43","author":"D Viggiano","year":"2018","unstructured":"Viggiano, D., Gigliotti, G., Vallone, G., Giammarino, A., Nigro, M., & Capasso, G. (2018). Urate-lowering agents in asymptomatic hyperuricemia: Role of urine sediment analysis and musculoskeletal ultrasound. Kidney & Blood Pressure Research, 43(2), 606\u2013615. https:\/\/doi.org\/10.1159\/000489145","journal-title":"Kidney & Blood Pressure Research"},{"issue":"8","key":"1161_CR44","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/s41581-020-0266-9","volume":"16","author":"D Viggiano","year":"2020","unstructured":"Viggiano, D., Wagner, C. A., Martino, G., et al. (2020). Mechanisms of cognitive dysfunction in CKD. Nature Reviews. Nephrology, 16(8), 452\u2013469. https:\/\/doi.org\/10.1038\/s41581-020-0266-9","journal-title":"Nature Reviews. Nephrology"},{"issue":"10075","key":"1161_CR2","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1016\/S0140-6736(16)32064-5","volume":"389","author":"AC Webster","year":"2017","unstructured":"Webster, A. C., Nagler, E. V., Morton, R. L., & Masson, P. (2017). Chronic kidney disease. Lancet, 389(10075), 1238\u20131252. https:\/\/doi.org\/10.1016\/S0140-6736(16)32064-5","journal-title":"Lancet"},{"key":"1161_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2024.120524","volume":"288","author":"L Xie","year":"2024","unstructured":"Xie, L., Zhang, Y., Hong, H., et al. (2024). Higher intracranial arterial pulsatility is associated with presumed imaging markers of the glymphatic system: An explorative study. NeuroImage, 288, Article 120524. https:\/\/doi.org\/10.1016\/j.neuroimage.2024.120524","journal-title":"NeuroImage"},{"issue":"25","key":"1161_CR50","doi-asserted-by":"publisher","first-page":"10306","DOI":"10.1073\/pnas.1222895110","volume":"110","author":"G Yang","year":"2013","unstructured":"Yang, G., Parkhurst, C. N., Hayes, S., & Gan, W. B. (2013). Peripheral elevation of TNF-\u03b1 leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America, 110(25), 10306\u201311. https:\/\/doi.org\/10.1073\/pnas.1222895110","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"1161_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0304762","volume":"19","author":"J Zhang","year":"2024","unstructured":"Zhang, J., Wu, L., Wang, P., et al. (2024). Prevalence of cognitive impairment and its predictors among chronic kidney disease patients: A systematic review and meta-analysis. PLoS One, 19(6), Article e0304762. https:\/\/doi.org\/10.1371\/journal.pone.0304762","journal-title":"PLoS One"},{"issue":"1","key":"1161_CR37","doi-asserted-by":"publisher","first-page":"115","DOI":"10.14336\/AD.2023.0516","volume":"15","author":"H Zhao","year":"2024","unstructured":"Zhao, H., Sun, M., Zhang, Y., et al. (2024). Connecting the dots: The cerebral lymphatic system as a bridge between the central nervous system and peripheral system in health and disease. Aging and Disease, 15(1), 115\u2013152. https:\/\/doi.org\/10.14336\/AD.2023.0516","journal-title":"Aging and Disease"},{"key":"1161_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1222857","volume":"17","author":"J Zhong","year":"2023","unstructured":"Zhong, J., Zhang, X., Xu, H., et al. (2023). Unlocking the enigma: Unraveling multiple cognitive dysfunction linked to glymphatic impairment in early Alzheimer\u2019s disease. Frontiers in Neuroscience, 17, Article 1222857. https:\/\/doi.org\/10.3389\/fnins.2023.1222857","journal-title":"Frontiers in Neuroscience"},{"issue":"1","key":"1161_CR21","doi-asserted-by":"publisher","first-page":"e25293","DOI":"10.1002\/jnr.25293","volume":"102","author":"Q Zhou","year":"2024","unstructured":"Zhou, Q., Zhang, C., Du, J., et al. (2024). Altered neurovascular coupling in migraine without aura. J Neurosci Res Jan, 102(1), e25293. https:\/\/doi.org\/10.1002\/jnr.25293","journal-title":"J Neurosci Res Jan"}],"container-title":["Brain Imaging and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11682-026-01161-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11682-026-01161-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11682-026-01161-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T07:18:16Z","timestamp":1784531896000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11682-026-01161-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,9]]},"references-count":50,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["1161"],"URL":"https:\/\/doi.org\/10.1007\/s11682-026-01161-7","relation":{},"ISSN":["1931-7565"],"issn-type":[{"value":"1931-7565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,9]]},"assertion":[{"value":"15 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethical approval was granted by the Ethics Committee of Beijing Friendship Hospital, Capital Medical University (approval number: 2022-P2-363-0). The study adhered to the principles outlined in the Declaration of Helsinki. Written informed consent was obtained from all participants before enrollment.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"93"}}