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This trial was approved by the Chinese Ethics Committee of Registering Clinical Trials and the clinical trial registration number was ChiCTR-TRC-13004223 (Date of registration: September 29, 2013) and the approved number of ethic committee was ChiECRCT-2013034 (Date of approved by ethic committee: December 2, 2013). Informed consent was obtained from all patients in this article.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethics guidelines"}}]}}