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This review focuses on the recent research and development of agents against ZIKV infection by repurposing clinical drugs. Their characteristics, targets, and potential use in anti-ZIKV therapy are presented. This review provides an update and some successful strategies in the search for anti-ZIKV agents are given.<\/jats:p>","DOI":"10.1007\/s11684-021-0834-9","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T14:02:49Z","timestamp":1609164169000},"page":"404-415","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Repurposing clinical drugs is a promising strategy to discover drugs against Zika virus infection"],"prefix":"10.1007","volume":"15","author":[{"given":"Weibao","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxing","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiandong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,12,28]]},"reference":[{"issue":"3","key":"834_CR1","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1128\/CMR.00072-15","volume":"29","author":"D Musso","year":"2016","unstructured":"Musso D, Gubler DJ. 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