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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the <i>Helsinki Declaration<\/i> of 1975, as revised in 2000. Informed consent was obtained from all patients for being included in the study. All institutional and national guidelines for the care and use of laboratory animals were followed.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethics guidelines"}}]}}