{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:04:24Z","timestamp":1783728264338,"version":"3.55.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Parasit."],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Malaria remains a major public health issue in the world despite a decline in the disease burden. However, though symptomatic malaria is diagnosed and treated, asymptomatic infections remain poorly known and support transmission. This study assessed the prevalence of symptomatic and asymptomatic\n                      <jats:italic>Plasmodium<\/jats:italic>\n                      spp. infections in three areas in Gabon to monitor and evaluate the impact of malaria.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      A cross-sectional study was conducted in three areas of Gabon. Febrile and afebrile children aged 6 months to 15 years were included in this study. Malaria prevalence was determined by microscopy of and using rapid diagnostic test (RDT).\n                      <jats:italic>Plasmodium<\/jats:italic>\n                      spp. species were identified by PCR according to the Snounou method. The data were recorded in Excel, and the statistical analyses were performed using the software R version R 64\u2009\u00d7\u20093.5.0. A total of 2381(333 asymptomatic and 107 symptomatic) children were included. The overall prevalence of malaria was 40% (952\/2381), with the majority (77% symptomatic and 98% asymptomatic) of infections caused by\n                      <jats:italic>Plasmodium falciparum<\/jats:italic>\n                      . A high prevalence of malaria was found in infected children in rural and semi-rural areas. In these two areas, a higher prevalence of\n                      <jats:italic>Plasmodium malariae<\/jats:italic>\n                      was observed in asymptomatic. Furthermore, mixed infections were more prevalent in asymptomatic children than in symptomatic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This study showed that the prevalence of\n                      <jats:italic>Plasmodium<\/jats:italic>\n                      spp. infection varied according to the regions. The main species was\n                      <jats:italic>Plasmodium falciparum<\/jats:italic>\n                      , but in asymptomatic children the prevalence of\n                      <jats:italic>Plasmodium malariae<\/jats:italic>\n                      was high in rural areas. To help fight malaria more effectively asymptomatic infections should be taken into account and treated.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11686-023-00783-x","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T05:02:58Z","timestamp":1704776578000},"page":"471-482","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Malaria Prevalence in Asymptomatic and Symptomatic Children Living in Rural, Semi-Urban and Urban Areas in Eastern Gabon"],"prefix":"10.1007","volume":"69","author":[{"given":"Lady Charl\u00e8ne","family":"Kouna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine Lydie","family":"Oyegue-Liabagui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique Fatima","family":"Voumbo-Matoumona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9417-1358","authenticated-orcid":false,"given":"Jean Bernard","family":"Lekana-Douki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"783_CR1","unstructured":"World health organisation (2020) World malaria report 2019. https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2019. 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Verbal consent was also obtained from all included children who were able to express themselves.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}