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The current study\u2019s goal was to assess the effectiveness of the ethanolic extract of <i>Z. officinale<\/i> in treating mice that had been infected with the RH <i>T. gondii<\/i> strain experimentally. Findings in the present study - as demonstrated by prolonged survival rate, reduced parasite burden, improved <i>T.gondii<\/i> associated liver injury and histopathological alterations - supported the strong therapeutic potential of ginger in the treatment of toxoplasmosis. We hypothesize that the antioxidant capacity of ginger is the underlying mechanism of its anti-<i>Toxoplasma<\/i> effect in the current study. Thus, our results suggested ginger can be considered a safe chemotherapeutic agent in the treatment of toxoplasmosis. Further studies are needed to determine the effective component in ginger which can be used as a pharmaceutical target in treatment of toxoplasmosis.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of Novelty"}},{"value":"This study was conducted after approval from the Ethics Committee of the Faculty of Medicine, Alexandria University, Egypt (<b>code: 0306090<\/b>). All animal experiments were conducted in accordance with the Declaration of Helsinki guidelines.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institutional Review Board Statement"}},{"value":"The authors have no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}