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After 24\u00a0h, the following treatment protocol was applied to the groups for five days: G-1: Albendazole (ABZ) (100\u00a0mg\/kg), G-2: Leaf Extract (10\u00a0mg\/mL)\u2009+\u2009ABZ (100\u00a0mg\/kg), G-3: Leaf Extract (40\u00a0mg\/mL)\u2009+\u2009ABZ (100\u00a0mg\/kg), G-4: Rhizome Extract\u2009+\u2009ABZ (100\u00a0mg\/kg), G-5: Leaf Extract (10\u00a0mg\/mL), G-6: Leaf Extract (40\u00a0mg\/mL), G-7: Rhizome extract, G-8: Negative control. The necropsy was performed on the 45th day of experimental infection.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The rhizome extract significantly reduced the effectiveness of ABZ compared to leaf extracts. The number of larvae in rhizome extract-treated mice (G7) was similar to ABZ-treated mice (G1) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The larval number in mice administered leaf extract (10\u00a0mg\/mL and 40\u00a0mg\/mL) was slightly decreased. But no significant difference was detected in the larval number depending on the dose of leaf extracts (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The administration of the leaf and rhizome extracts did not contribute to the effectiveness of ABZ. Also the effect of ABZ on the larvae number obtained from the tissues was reduced by the rhizome extract. The larvae number in the group in which rhizome extract was given alone was almost close to the group in which ABZ was administered. The results provide insight for further research on the antiparasitic properties of <jats:italic>A. rupicola<\/jats:italic> Boiss <jats:italic>rupicola<\/jats:italic> rhizome extract.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s11686-024-00970-4","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T13:55:54Z","timestamp":1737726954000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Arum rupicola Boiss rupicola Extracts on Visceral Larva Migrans in Mice"],"prefix":"10.1007","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6207-9664","authenticated-orcid":false,"given":"Gozde Nur","family":"Akkus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4225-4071","authenticated-orcid":false,"given":"Tugrul","family":"Atalay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6078-460X","authenticated-orcid":false,"given":"Sinem","family":"Akdeniz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6403-737X","authenticated-orcid":false,"given":"Husamettin","family":"Ekici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3429-7223","authenticated-orcid":false,"given":"Dincer","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0738-1518","authenticated-orcid":false,"given":"I. 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