{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:55:07Z","timestamp":1790258107714,"version":"4.1.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["OBES SURG"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1007\/s11695-015-1633-7","type":"journal-article","created":{"date-parts":[[2015,2,28]],"date-time":"2015-02-28T21:46:06Z","timestamp":1425159966000},"page":"1802-1809","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Expedited Biliopancreatic Juice Flow to the Distal Gut Benefits the Diabetes Control After Duodenal-Jejunal Bypass"],"prefix":"10.1007","volume":"25","author":[{"given":"Haifeng","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxiao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaozhuang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanyuan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,3,1]]},"reference":[{"issue":"1","key":"1633_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.sla.0000102989.54824.fc","volume":"239","author":"F Rubino","year":"2004","unstructured":"Rubino F, Marescaux J. Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg. 2004;239(1):1\u201311.","journal-title":"Ann Surg"},{"issue":"4","key":"1633_CR2","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.2337\/db12-0681","volume":"62","author":"J Jiao","year":"2013","unstructured":"Jiao J, Bae EJ, Bandyopadhyay G, et al. Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in Zucker fa\/fa rats. Diabetes. 2013;62(4):1074\u201383.","journal-title":"Diabetes"},{"issue":"1","key":"1633_CR3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/SLA.0b013e3182890311","volume":"258","author":"CF Jurowich","year":"2013","unstructured":"Jurowich CF, Rikkala PR, Thalheimer A, et al. Duodenal-jejunal bypass improves glycemia and decreases SGLT1-mediated glucose absorption in rats with streptozotocin-induced type 2 diabetes. Ann Surg. 2013;258(1):89\u201397.","journal-title":"Ann Surg"},{"issue":"5","key":"1633_CR4","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1097\/01.sla.0000224726.61448.1b","volume":"244","author":"F Rubino","year":"2006","unstructured":"Rubino F, Forgione A, Cummings DE, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006;244(5):741\u20139.","journal-title":"Ann Surg"},{"issue":"10","key":"1633_CR5","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1007\/s11605-009-0912-9","volume":"13","author":"TL Kindel","year":"2009","unstructured":"Kindel TL, Yoder SM, Seeley RJ, et al. Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. J Gastrointest Surg. 2009;13(10):1762\u201372.","journal-title":"J Gastrointest Surg"},{"issue":"9","key":"1633_CR6","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1038\/oby.2009.102","volume":"17","author":"ME Patti","year":"2009","unstructured":"Patti ME, Houten SM, Bianco AC, et al. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring). 2009;17(9):1671\u20137.","journal-title":"Obesity (Silver Spring)"},{"issue":"2","key":"1633_CR7","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1242\/dmm.010421","volume":"6","author":"BP Cummings","year":"2013","unstructured":"Cummings BP, Bettaieb A, Graham JL, et al. Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats. Dis Model Mech. 2013;6(2):443\u201356.","journal-title":"Dis Model Mech"},{"issue":"12","key":"1633_CR8","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1007\/s11695-014-1308-9","volume":"24","author":"H Han","year":"2014","unstructured":"Han H, Hu C, Wang L, et al. Duodenal-jejunal bypass surgery suppresses hepatic de novo lipogenesis and alleviates liver fat accumulation in a diabetic rat model. Obes Surg. 2014;24(12):2152\u201360.","journal-title":"Obes Surg"},{"issue":"7","key":"1633_CR9","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1038\/sj.emboj.7601049","volume":"25","author":"SM Houten","year":"2006","unstructured":"Houten SM, Watanabe M, Auwerx J. Endocrine functions of bile acids. EMBO J. 2006;25(7):1419\u201325.","journal-title":"EMBO J"},{"issue":"4","key":"1633_CR10","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1172\/JCI25604","volume":"116","author":"K Ma","year":"2006","unstructured":"Ma K, Saha PK, Chan L, et al. Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest. 2006;116(4):1102\u20139.","journal-title":"J Clin Invest"},{"issue":"10","key":"1633_CR11","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1172\/JCI21025","volume":"113","author":"M Watanabe","year":"2004","unstructured":"Watanabe M, Houten SM, Wang L, et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest. 2004;113(10):1408\u201318.","journal-title":"J Clin Invest"},{"issue":"3","key":"1633_CR12","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.cmet.2009.08.001","volume":"10","author":"C Thomas","year":"2009","unstructured":"Thomas C, Gioiello A, Noriega L, et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009;10(3):167\u201377.","journal-title":"Cell Metab"},{"issue":"4","key":"1633_CR13","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/01.sla.0000089851.41115.1b","volume":"238","author":"PR Schauer","year":"2003","unstructured":"Schauer PR, Burguera B, Ikramuddin S, et al. Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg. 2003;238(4):467\u201384. discussion 84\u20135.","journal-title":"Ann Surg"},{"issue":"6","key":"1633_CR14","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1097\/SLA.0b013e318172504d","volume":"247","author":"TT Wang","year":"2008","unstructured":"Wang TT, Hu SY, Gao HD, et al. Ileal transposition controls diabetes as well as modified duodenal jejunal bypass with better lipid lowering in a nonobese rat model of type II diabetes by increasing GLP-1. Ann Surg. 2008;247(6):968\u201375.","journal-title":"Ann Surg"},{"issue":"3","key":"1633_CR15","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.amjmed.2008.09.041","volume":"122","author":"H Buchwald","year":"2009","unstructured":"Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med. 2009;122(3):248\u201356. 3.","journal-title":"Am J Med"},{"issue":"4","key":"1633_CR16","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1365-2362.1992.tb01464.x","volume":"22","author":"R Eissele","year":"1992","unstructured":"Eissele R, Goke R, Willemer S, et al. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Investig. 1992;22(4):283\u201391.","journal-title":"Eur J Clin Investig"},{"issue":"4","key":"1633_CR17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.phrs.2005.05.004","volume":"52","author":"K Srinivasan","year":"2005","unstructured":"Srinivasan K, Viswanad B, Asrat L, et al. Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol Res. 2005;52(4):313\u201320.","journal-title":"Pharmacol Res"},{"issue":"5","key":"1633_CR18","first-page":"912","volume":"125","author":"SZ Liu","year":"2012","unstructured":"Liu SZ, Sun D, Zhang GY, et al. A high-fat diet reverses improvement in glucose tolerance induced by duodenal-jejunal bypass in type 2 diabetic rats. Chin Med J. 2012;125(5):912\u20139.","journal-title":"Chin Med J"},{"issue":"6","key":"1633_CR19","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1097\/SLA.0b013e31826c3866","volume":"256","author":"S Liu","year":"2012","unstructured":"Liu S, Zhang G, Wang L, et al. The entire small intestine mediates the changes in glucose homeostasis after intestinal surgery in Goto-Kakizaki rats. Ann Surg. 2012;256(6):1049\u201358.","journal-title":"Ann Surg"},{"issue":"14","key":"1633_CR20","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1001\/jama.292.14.1724","volume":"292","author":"H Buchwald","year":"2004","unstructured":"Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724\u201337.","journal-title":"JAMA"},{"issue":"3","key":"1633_CR21","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/00000658-199509000-00011","volume":"222","author":"WJ Pories","year":"1995","unstructured":"Pories WJ, Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg. 1995;222(3):339\u201350. discussion 50\u20132.","journal-title":"Ann Surg"},{"issue":"6","key":"1633_CR22","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1210\/en.2009-0367","volume":"150","author":"JP Thaler","year":"2009","unstructured":"Thaler JP, Cummings DE. Minireview: hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery. Endocrinology. 2009;150(6):2518\u201325.","journal-title":"Endocrinology"},{"issue":"11","key":"1633_CR23","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1007\/s00125-009-1511-8","volume":"52","author":"FK Knop","year":"2009","unstructured":"Knop FK. Resolution of type 2 diabetes following gastric bypass surgery: involvement of gut-derived glucagon and glucagonotropic signalling? Diabetologia. 2009;52(11):2270\u20136.","journal-title":"Diabetologia"},{"issue":"3","key":"1633_CR24","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s11695-013-1103-z","volume":"24","author":"SY Zhang","year":"2014","unstructured":"Zhang SY, Sun XJ, Zheng JB, et al. Preserve common limb in duodenal-jejunal bypass surgery benefits rats with type 2-like diabetes. Obes Surg. 2014;24(3):405\u201311.","journal-title":"Obes Surg"},{"issue":"6","key":"1633_CR25","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1053\/j.gastro.2007.03.054","volume":"132","author":"LL Baggio","year":"2007","unstructured":"Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology. 2007;132(6):2131\u201357.","journal-title":"Gastroenterology"},{"issue":"1","key":"1633_CR26","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1172\/JCI30076","volume":"117","author":"DJ Drucker","year":"2007","unstructured":"Drucker DJ. The role of gut hormones in glucose homeostasis. J Clin Invest. 2007;117(1):24\u201332.","journal-title":"J Clin Invest"},{"key":"1633_CR27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1196\/annals.1317.006","volume":"1070","author":"PL Brubaker","year":"2006","unstructured":"Brubaker PL. The glucagon-like peptides: pleiotropic regulators of nutrient homeostasis. Ann N Y Acad Sci. 2006;1070:10\u201326.","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"1633_CR28","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1111\/j.1476-5381.2011.01561.x","volume":"165","author":"HE Parker","year":"2012","unstructured":"Parker HE, Wallis K, le Roux CW, et al. Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br J Pharmacol. 2012;165(2):414\u201323.","journal-title":"Br J Pharmacol"},{"issue":"4","key":"1633_CR29","doi-asserted-by":"crossref","first-page":"E718","DOI":"10.1210\/jc.2012-3961","volume":"98","author":"T Wu","year":"2013","unstructured":"Wu T, Bound MJ, Standfield SD, et al. Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans. J Clin Endocrinol Metab. 2013;98(4):E718\u201322.","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"1633_CR30","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1210\/en.2012-2069","volume":"154","author":"R Kohli","year":"2013","unstructured":"Kohli R, Setchell KD, Kirby M, et al. A surgical model in male obese rats uncovers protective effects of bile acids post-bariatric surgery. Endocrinology. 2013;154(7):2341\u201351.","journal-title":"Endocrinology"},{"issue":"8","key":"1633_CR31","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1210\/en.2011-2145","volume":"153","author":"DJ Pournaras","year":"2012","unstructured":"Pournaras DJ, Glicksman C, Vincent RP, et al. The role of bile after Roux-en-Y gastric bypass in promoting weight loss and improving glycaemic control. Endocrinology. 2012;153(8):3613\u20139.","journal-title":"Endocrinology"},{"issue":"3","key":"1633_CR32","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.2337\/db13-0856","volume":"63","author":"S Salinari","year":"2014","unstructured":"Salinari S, le Roux CW, Bertuzzi A, et al. Duodenal-jejunal bypass and jejunectomy improve insulin sensitivity in Goto-Kakizaki diabetic rats without changes in incretins or insulin secretion. Diabetes. 2014;63(3):1069\u201378.","journal-title":"Diabetes"},{"issue":"5","key":"1633_CR33","doi-asserted-by":"crossref","first-page":"E923","DOI":"10.1152\/ajpendo.00422.2010","volume":"300","author":"M Speck","year":"2011","unstructured":"Speck M, Cho YM, Asadi A, et al. Duodenal-jejunal bypass protects GK rats from {beta}-cell loss and aggravation of hyperglycemia and increases enteroendocrine cells coexpressing GIP and GLP-1. Am J Physiol Endocrinol Metab. 2011;300(5):E923\u201332.","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"12","key":"1633_CR34","doi-asserted-by":"crossref","first-page":"E660","DOI":"10.1002\/oby.20522","volume":"21","author":"RE Steinert","year":"2013","unstructured":"Steinert RE, Peterli R, Keller S, et al. Bile acids and gut peptide secretion after bariatric surgery: a 1-year prospective randomized pilot trial. Obesity (Silver Spring). 2013;21(12):E660\u20138.","journal-title":"Obesity (Silver Spring)"},{"issue":"3","key":"1633_CR35","doi-asserted-by":"crossref","first-page":"G652","DOI":"10.1152\/ajpgi.00221.2010","volume":"299","author":"R Kohli","year":"2010","unstructured":"Kohli R, Kirby M, Setchell KD, et al. Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol. 2010;299(3):G652\u201360.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"7075","key":"1633_CR36","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/nature04330","volume":"439","author":"M Watanabe","year":"2006","unstructured":"Watanabe M, Houten SM, Mataki C, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006;439(7075):484\u20139.","journal-title":"Nature"},{"issue":"4","key":"1633_CR37","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nm.3525","volume":"20","author":"F Kuipers","year":"2014","unstructured":"Kuipers F, Groen AK. FXR: the key to benefits in bariatric surgery? Nat Med. 2014;20(4):337\u20138.","journal-title":"Nat Med"},{"issue":"4","key":"1633_CR38","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1172\/JCI110668","volume":"70","author":"B Angelin","year":"1982","unstructured":"Angelin B, Bjorkhem I, Einarsson K, et al. Hepatic uptake of bile acids in man. Fasting and postprandial concentrations of individual bile acids in portal venous and systemic blood serum. J Clin Investig. 1982;70(4):724\u201331.","journal-title":"J Clin Investig"},{"issue":"10","key":"1633_CR39","doi-asserted-by":"crossref","first-page":"3384","DOI":"10.2337\/db13-0299","volume":"62","author":"A Mencarelli","year":"2013","unstructured":"Mencarelli A, Renga B, D\u2019Amore C, et al. Dissociation of intestinal and hepatic activities of FXR and LXR\u03b1 supports metabolic effects of terminal ileum interposition in rodents. Diabetes. 2013;62(10):3384\u201393.","journal-title":"Diabetes"}],"container-title":["Obesity Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11695-015-1633-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11695-015-1633-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11695-015-1633-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T02:43:30Z","timestamp":1651373010000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11695-015-1633-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,1]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["1633"],"URL":"https:\/\/doi.org\/10.1007\/s11695-015-1633-7","relation":{},"ISSN":["0960-8923","1708-0428"],"issn-type":[{"value":"0960-8923","type":"print"},{"value":"1708-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,1]]}}}