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FR reports receiving research grants from Ethicon and Medtronic; receiving consulting fees from Novo Nordisk, Ethicon, Eli Lilly, Kaiser, Astra Zeneca and Medtronic; and serving on scientific advisory boards for GI Dynamics and Keyron. GM reports grants and personal fees from Novo Nordisk and Fractyl and personal fees from Johnson & Johnson, outside the submitted work. ACR reports research activity is supported by Centers for Disease Control and Prevention (CDC), the National Heart, Lung, Blood Institute\/National Institutes of Health (NHLBI\/NIH), University of Michigan\/ the National Institute on Aging (NIA)\/NIH, Viiv Healthcare, Prisma Health Seed Grant program, the Duke Endowment and the Blue Cross Blue Shield South Carolina Foundation. All other authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"The study was supported by an investigator-initiated grant from Johnson & Johnson (Ethicon). 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