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After an overnight fast and a standardised breakfast, participants performed AEX or CON, and both conditions were followed by an identical lunch administered as a mixed-meal tolerance test (MMTT). Continuous glucose monitoring (CGM) assessed glucose levels for 24-h post-intervention, during which participants consumed standardised meals.\n                      <jats:bold>CGM data were available for analysis in 11 participants.<\/jats:bold>\n                      The primary outcome was time spent with glucose &lt;3.0 mmol\/L during the 24-h post-intervention. Secondary outcomes included other CGM-derived glucose metrics and plasma glucose and insulin responses during the 3-h MMTT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Only one isolated hypoglycaemic event (&lt;3.0 mmol\/L) occurred, precluding statistical analysis of the primary outcome. Mean 24-h glucose (AEX: 6.4 (1.0); CON: 6.5 (0.9) mmol\/L; p = 0.57) and time &lt;3.9 mmol\/L (AEX 0 (0.0, 0.5); CON 0 (0.0, 0.5) %; p = 0.68) did not differ between conditions. AEX reduced glucose coefficient of variation (p &lt; 0.01). During the MMTT, nadir, peak, and AUC\n                      <jats:sub>0-180<\/jats:sub>\n                      glucose, as well as pre-MMTT insulin concentrations, were higher following AEX (all p &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A pre-lunch 30-min bout of AEX did not increase the 24-h risk of hypoglycaemia post-MBS but elevated post-MMTT glucose levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11695-026-08712-3","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:54:53Z","timestamp":1777643693000},"page":"3058-3070","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Acute Aerobic Exercise On the Time Spent in Hypoglycaemia After Bariatric Surgery (The BariEX Study)"],"prefix":"10.1007","volume":"36","author":[{"given":"Israel","family":"Podesta-Donoso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitris","family":"Papamargaritis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Henson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislava","family":"Katsarova-Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aikaterina","family":"Tziannou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Waller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex V","family":"Rowlands","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bowrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwaseun","family":"Anyiam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iskandar","family":"Idris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Stensel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjali","family":"Zalin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Yates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Choudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie J","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louisa Y","family":"Herring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"issue":"3","key":"8712_CR1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/joim.12012","volume":"273","author":"L Sj\u00f6str\u00f6m","year":"2013","unstructured":"Sj\u00f6str\u00f6m L. 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The study was registered in the ISRCTN registry (ISRCTN 17674908). All study procedures were carried out in accordance with good clinical practice guidelines and the Declaration of Helsinki (1964).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"All participants provided written informed consent prior to being enrolled onto the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"I. Podesta, J. Henson, S. Katsarova-Harrison, A. Tziannou, H. Waller, A. V. Rowlands, D. Bowery, O Anyiam, D. J. Stensel, D. R. Webb, A. Zalin, and L. Y. Herring declare no competing financial interests. D. Papamargaritis has received honoraria for acting as a speaker for Novo Nordisk, Eli Lilly, Boehringer Ingelheim, and Johnson & Johnson. He has received consultancy fees from Regeneron. He has also received research funding from Novo Nordisk, the Novo Nordisk UK Research Foundation, the Academy of Medical Sciences\/Diabetes UK, Health Education East Midlands, and the National Institute for Health and Care Research (NIHR). I. Idris has received honoraria\/funding for acting as a speaker and researcher for Novo Nordisk, Eli Lilly, Boehringer Ingelheim, Sanofi, Abbott, and Johnson & Johnson. T. Yates has received investigator-initiated funding from AstraZeneca, contracted research funding from the Reinsurance Group of America and has acted as a consultant for Regeneron. Professor Choudhary has served as a consultant for Cambridge Mechatronics Ltd, as well as an advisory board member and speaker for Medtronic, Novo Nordisk, Sanofi, Lilly, Abbott, Insulet, AstraZeneca, Dexcom, Glooko, and Roche. Advisory board member for Ypsomed, Embecta, Tandem and Vertex. He has received research support from Medtronic, Abbott, Novo Nordisk, Dexcom and Insulet. Professor Davies has acted as a consultant\/advisor and speaker for Eli Lilly, Novo Nordisk and Sanofi, has attended advisory boards for AbbVie, Amgen, AstraZeneca, Biomea Fusion, Carmot\/Roche, Daewoong Pharmaceutical, Sanofi, Zealand Pharma, Regeneron, GSK and EktaH and as a speaker for AstraZeneca, Boehringer Ingelheim and Zuellig Pharma. She has received grants from AstraZeneca, Boehringer Ingelheim and Novo Nordisk.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}