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This study is an update of the 2021 systematic review on weight loss after MBS expressed in %TWL, now including results of one anastomosis gastric bypass (OAGB), Roux-en-Y gastric bypass (RYGB), and sleeve gastrectomy (SG). A total of 4,541 records were screened, and 49 studies were included, comprising both cohort and registry-based data. Descriptive pooled estimates suggested that OAGB was associated with the highest nadir %TWL within the first two years, whereas nadir %TWL appeared comparable between RYGB and SG. During longer-term follow-up, OAGB appeared to maintain a higher pooled mean %TWL than RYGB and SG. These findings should be interpreted cautiously given the heterogeneity of included studies and the limited availability of long-term data. They should be balanced against long-term complications and need for revisional surgery, which were beyond the scope of the present review. Standardized reporting and high-quality studies with extended follow-up using %TWL as the primary outcome are needed to improve comparability and interpretation of long-term weight loss after bariatric surgery.<\/jats:p>","DOI":"10.1007\/s11695-026-08766-3","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T14:16:02Z","timestamp":1781273762000},"page":"3932-3946","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["What is Weight Loss after Bariatric Surgery Expressed in Percentage Total Weight Loss (%TWL)? 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