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Integrity of research and reporting: The manuscript has not been submitted to more than one journal for simultaneous consideration. The manuscript has not been published previously (partly or in full). A single study is not split up into several parts to increase the quantity of submissions and submitted to various journals or to one journal over time (e.g., \u201csalami-publishing\u201d). No data have been fabricated or manipulated (including images) to support conclusions. No data, text, or theories by others are presented as if they were the author\u2019s own (\u201cplagiarism\u201d). Consent to submit has been received explicitly from all co-authors, as well as from the responsible authorities\u2014tacitly or explicitly\u2014at the institute\/organization where the work has been carried out, before the work is submitted. Authors whose names appear on the submission have contributed sufficiently to the scientific work, and therefore, share collective responsibility and accountability for the results. Upon request authors are prepared to send relevant documentation or data to verify the validity of the results. This could be in the form of raw data, samples, records, etc. All procedures followed were in accordance with the ethical standards of the Institutional Ethical Committee and with the Helsinki Declaration of 1975, as revised in 2000. Informed consent was obtained from all patients for being included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}