{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:32:48Z","timestamp":1772119968331,"version":"3.50.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:00:00Z","timestamp":1712966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:00:00Z","timestamp":1712966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Robotic Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Prostate cancer patients often have other health conditions and take anticoagulants. It was believed that surgery under anticoagulants could worsen surgical results. This study aims to explore the safety of robot-assisted prostatectomy in anticoagulated patients, without any exclusion criteria. The study included 500 patients who underwent RARP by a single surgeon between April 2019 and August 2022. Patients were divided into two groups: Group 1, consisting of 376 men (75.2%), did not receive any anticoagulation, while Group 2, with 124 patients (24.8%), received different forms of anticoagulation. Then, the anticoagulation group was divided into 4 subgroups according to their definite anticoagulation: the aspirin 15.6%, new oral anticoagulants (NOAC) 5.4%, Vitamin K antagonist (VKA) 2%, and dual-antiplatelet therapy (DAPT) 1.8% subgroup. Postoperative complications and readmission rates were compared between the two study groups and subgroups. Patients in the combined group 2 were older and they also carried more comorbidities compared to men in group 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.03,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.001).The study groups had similar oncological results, with 40.4% of patients having locally advanced cancers. Catheter days were longer in the anticoagulation group (4.5 vs 4\u00a0days,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.001). No significant differences were observed between study groups for overall, minor, and major complications (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.160, 0.100, and 0.915, respectively). In addition, readmissions were low (5.6%) and similar between the study groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.635). Under cautious management, RARP under diverse anticoagulation regimes is safe and has comparable results to men with no medications. Further prospective studies must be conducted to confirm our findings.\n                  <\/jats:p>","DOI":"10.1007\/s11701-024-01933-7","type":"journal-article","created":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T08:01:53Z","timestamp":1712995313000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["On the relationship between various anticoagulants and robot-assisted radical prostatectomy: a single-surgeon serial analysis"],"prefix":"10.1007","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1989-2187","authenticated-orcid":false,"given":"Mahmoud","family":"Farzat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2909-0797","authenticated-orcid":false,"given":"Florian M.","family":"Wagenlehner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,13]]},"reference":[{"issue":"3","key":"1933_CR1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209\u2013249","journal-title":"CA Cancer J Clin"},{"issue":"8","key":"1933_CR2","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/s11886-023-01909-3","volume":"25","author":"CT Ng","year":"2023","unstructured":"Ng CT, Bonilla HMG, Bryce AH, Singh P, Herrmann J (2023) Approaches to prevent and manage cardiovascular disease in patients receiving therapy for prostate cancer. Curr Cardiol Rep 25(8):889\u2013899","journal-title":"Curr Cardiol Rep"},{"key":"1933_CR3","doi-asserted-by":"publisher","first-page":"2976811","DOI":"10.1155\/2022\/2976811","volume":"2022","author":"P Davey","year":"2022","unstructured":"Davey P, Alexandrou K (2022) Assessment and mitigation of cardiovascular risk for prostate cancer patients: a review of the evidence. Int J Clin Pract 2022:2976811","journal-title":"Int J Clin Pract"},{"issue":"6","key":"1933_CR4","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1016\/j.urology.2008.06.057","volume":"72","author":"LS Krane","year":"2008","unstructured":"Krane LS, Laungani R, Satyanarayana R, Kaul S, Bhandari M, Peabody JO et al (2008) Robotic-assisted radical prostatectomy in patients receiving chronic anticoagulation therapy: role of perioperative bridging. Urology 72(6):1351\u20131355","journal-title":"Urology"},{"issue":"6","key":"1933_CR5","first-page":"2085","volume":"26","author":"YJ Ning","year":"2022","unstructured":"Ning YJ, Wan ZX, Meng J, Wang XP (2022) A systemic review and meta-analysis of the effects of perioperative anticoagulant and antiplatelet therapy on bleeding complications in robot-assisted prostatectomy. Eur Rev Med Pharmacol Sci 26(6):2085\u20132097","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"3","key":"1933_CR6","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1111\/bju.12504","volume":"114","author":"SR Leyh-Bannurah","year":"2014","unstructured":"Leyh-Bannurah SR, Hansen J, Isbarn H, Steuber T, Tennstedt P, Michl U et al (2014) Open and robot-assisted radical retropubic prostatectomy in men receiving ongoing low-dose aspirin medication: revisiting an old paradigm? BJU Int 114(3):396\u2013403","journal-title":"BJU Int"},{"issue":"4","key":"1933_CR7","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1007\/s11701-021-01308-2","volume":"16","author":"S Sforza","year":"2022","unstructured":"Sforza S, Grosso AA, Di Maida F, Viola L, Tuccio A, Mari A et al (2022) A comparative study of anticoagulant\/antiplatelet therapy among men undergoing robot-assisted radical prostatectomy: a prospective single institution study. 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J Robot Surg 15(4):661\u2013670","journal-title":"J Robot Surg"},{"issue":"9","key":"1933_CR12","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1089\/end.2018.0390","volume":"32","author":"AS Tamhankar","year":"2018","unstructured":"Tamhankar AS, Patil SR, Ahluwalia P, Gautam G (2018) Does continuation of low-dose aspirin during robot-assisted radical prostatectomy compromise surgical outcomes? J Endourol 32(9):852\u2013858","journal-title":"J Endourol"}],"container-title":["Journal of Robotic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11701-024-01933-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11701-024-01933-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11701-024-01933-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T19:04:54Z","timestamp":1735067094000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11701-024-01933-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,13]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1933"],"URL":"https:\/\/doi.org\/10.1007\/s11701-024-01933-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3909416\/v1","asserted-by":"object"}]},"ISSN":["1863-2491"],"issn-type":[{"value":"1863-2491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,13]]},"assertion":[{"value":"29 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All data generated or analyzed during this study are included in this article. Further inquiries can be directed to the corresponding author.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"174"}}