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We retrospectively analyzed patients with stageI-IIIA NSCLC who underwent RATS or VATS at a hospital between 8 May 2020 and 31 December 2021. Analysis of leukocytes (including neutrophils and lymphocytes) and albumin on postoperative days (PODs) 1 and 3 in patients with NSCLC treated with RATS or VATS after propensity score matching (PSM). In total, 1824 patients (565 RATS and 1259 VATS) were investigated. The two MIS groups differed significantly with regard to operative time (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), chronic lung disease (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), the type of pulmonary resection (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), the excision site of lobectomy (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.004), and histology of the tumor (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.028). After PSM, leukocyte and neutrophil levels in the RATS group were lower than those in the VATS group on PODs 1 and 3, with those on POD 3 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) being particularly notable. While lymphocyte levels in the RATS group were significantly lower than those in the VATS group only at POD 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.016). There was no difference in albumin levels between the RATS and VATS groups on PODs 1 and 3. The surgical stress response and tissue trauma was less severe in NSCLC patients who underwent RATS than in those who underwent VATS, especially reflected in the neutrophils of leukocytes.\n                  <\/jats:p>","DOI":"10.1007\/s11701-024-01939-1","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T09:02:03Z","timestamp":1713344523000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Postoperative leukocyte counts as a surrogate for surgical stress response in matched robot- and video-assisted thoracoscopic surgery cohorts of patients: A preliminary report"],"prefix":"10.1007","volume":"18","author":[{"given":"Sidi","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huichao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelian","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaling","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"1939_CR1","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkaa031","author":"V Raman","year":"2020","unstructured":"Raman V, Christopher JK, Jawitz OK et al (2020) Robot- vs video-assisted thoracoscopic lobectomy for early lung cancer. 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Approval was granted by our hospital ethics committee (Xiangya Hospital of Central South University). The approval number is 202207390, the approval date July 12, 2022.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}],"article-number":"176"}}