{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T22:44:54Z","timestamp":1759099494967},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2008,6,17]],"date-time":"2008-06-17T00:00:00Z","timestamp":1213660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1007\/s11739-008-0163-x","type":"journal-article","created":{"date-parts":[[2008,6,16]],"date-time":"2008-06-16T17:52:31Z","timestamp":1213638751000},"page":"331-337","source":"Crossref","is-referenced-by-count":8,"title":["Prognostic value of brain natriuretic peptide and enhanced ventilatory response to exercise in patients with chronic heart failure"],"prefix":"10.1007","volume":"3","author":[{"given":"Angela Beatrice","family":"Scardovi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata","family":"De Maria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Celestini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Coletta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Aspromonte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Perna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Parolini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Ricci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,6,17]]},"reference":[{"key":"163_CR1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1053\/euhj.2000.2388","volume":"22","author":"Working Group on Cardiac Rehabilitation Exercise Physiology Working Group on Heart Failure of European Society of Cardiology","year":"2001","unstructured":"Working Group on Cardiac Rehabilitation Exercise Physiology Working Group on Heart Failure of European Society of Cardiology (2001) Recommendations for exercise testing in chronic heart failure patients. Eur Heart J 22:37\u201345","journal-title":"Eur Heart J"},{"key":"163_CR2","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.1161\/CIRCULATIONAHA.107.686576","volume":"115","author":"R Arena","year":"2007","unstructured":"Arena R, Myers J, Abella J et al (2007) Development of a ventilatory classification system in patients with heart failure. Circulation 115:2410\u20132417","journal-title":"Circulation"},{"key":"163_CR3","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1053\/euhj.2001.2783","volume":"22","author":"WJ Remme","year":"2001","unstructured":"Remme WJ, Swedberg K (2001) Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J 22:1527\u20131560","journal-title":"Eur Heart J"},{"key":"163_CR4","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0735-1097(98)00002-3","volume":"3","author":"C Opasich","year":"1998","unstructured":"Opasich C, Pinna GD, Bobbio M et al (1998) Peak exercise oxygen consumption in chronic heart failure: toward efficient use in the individual patient. J Am Coll Cardiol 3:766\u2013775","journal-title":"J Am Coll Cardiol"},{"key":"163_CR5","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0002-9149(97)00062-3","volume":"79","author":"W Kao","year":"1997","unstructured":"Kao W, Winkel EM, Johnson MR et al (1997) Role of maximal oxygen consumption in establishment of heart transplant candidacy for heart failure patients with intermediate exercise tolerance. Am J Cardiol 79:1124\u20131127","journal-title":"Am J Cardiol"},{"key":"163_CR6","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1067\/mhj.2002.120772","volume":"143","author":"U Corra","year":"2002","unstructured":"Corra U, Mezzani A, Bosimini E et al (2002) Ventilatory response to exercise improves risk stratification in patients with chronic heart failure and intermediate functional capacity. Am Heart J 143:418\u2013426","journal-title":"Am Heart J"},{"key":"163_CR7","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1161\/01.CIR.103.7.967","volume":"103","author":"P Ponikowski","year":"2001","unstructured":"Ponikowski P, Francis DP, Piepoli MF et al (2001) Enhanced ventilatory response to exercise in patients with chronic heart failure and preserved exercise tolerance. Marker of abnormal cardiorespiratory reflex control and predictor of poor prognosis. Circulation 103:967\u2013972","journal-title":"Circulation"},{"key":"163_CR8","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.cardfail.2007.03.004","volume":"13","author":"R Arena","year":"2007","unstructured":"Arena R, Myers J, Hsu L et al (2007) The minute ventilation\/carbon dioxide production slope is prognostically superior to the oxygen uptake efficiency slope. J Card Fail 13:462\u2013469","journal-title":"J Card Fail"},{"key":"163_CR9","first-page":"230","volume":"19","author":"V Thohan","year":"2004","unstructured":"Thohan V (2004) Prognostic implications of echocardiography in advanced heart failure. Curr Opin Cardiol 19:230\u2013249","journal-title":"Curr Opin Cardiol"},{"key":"163_CR10","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.jacc.2004.12.064","volume":"45","author":"C Bruch","year":"2005","unstructured":"Bruch C, Gotzmann M, Stypmann J et al (2005) Electrocardiography and Doppler echocardiography for risk stratification in patients with chronic heart failure. Incremental prognostic value of QRS duration and a restrictive mitral filling pattern. J Am Coll Cardiol 45:1072\u20131075","journal-title":"J Am Coll Cardiol"},{"key":"163_CR11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ijcard.2006.11.080","volume":"122","author":"GA Whalley","year":"2007","unstructured":"Whalley GA, Gamble GD, Dini FL et al (2007) Individual patient meta-analyses of restrictive diastolic filling pattern and mortality in patients post acute myocardial infarction and in patients with chronic heart failure. Int J Cardiol 122:207\u2013215","journal-title":"Int J Cardiol"},{"key":"163_CR12","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1111\/j.1527-5299.2004.03271.x","volume":"10","author":"MA Silver","year":"2004","unstructured":"Silver MA, Maisel A, Yancy CW et al (2004) BNP Consensus panel 2004: a clinical approach for the diagnostic, prognostic, screening, treatment monitoring, and therapeutic roles of natriuretic peptides in cardiovascular diseases. Congest Heart Fail 10:S1\u2013S30","journal-title":"Congest Heart Fail"},{"key":"163_CR13","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1378\/chest.120.6.2047","volume":"120","author":"L Cabanes","year":"2001","unstructured":"Cabanes L, Richaud-Thiriez B, Fulla YS et al (2001) Brain natriuretic peptide blood levels in the differential diagnosis of dyspnea. Chest 120:2047\u20132050","journal-title":"Chest"},{"key":"163_CR14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1056\/NEJMoa020233","volume":"347","author":"AS Maisel","year":"2002","unstructured":"Maisel AS, Krishnaswamy P, Nowak RM et al (2002) Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med 347:161\u2013167","journal-title":"N Engl J Med"},{"key":"163_CR15","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0002-8703(03)00365-X","volume":"146","author":"R Isnard","year":"2003","unstructured":"Isnard R, Pousset F, Chafirovskaia O et al (2003) Combination of B-type natriuretic peptide and peak oxygen consumption improves risk stratification in outpatients with chronic heart failure. Am Heart J 146:729\u2013735","journal-title":"Am Heart J"},{"key":"163_CR16","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.jacc.2003.11.059","volume":"43","author":"P Groote de","year":"2004","unstructured":"de Groote P, Dagorn JI, Soudan B et al (2004) B-type natriuretic peptide and peak exercise oxygen consumption provide independent information for risk stratification in patients with stable congestive heart failure. J Am Coll Cardiol 43:1584\u20131589","journal-title":"J Am Coll Cardiol"},{"key":"163_CR17","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/j.amjcard.2006.12.050","volume":"99","author":"DA Pascual-Figal","year":"2007","unstructured":"Pascual-Figal DA, Penafiel P, de la Morena G et al (2007) Relation of B-type natriuretic peptide levels before and after exercise and functional capacity in patients with idiopathic dilated cardiomyopathy. Am J Cardiol 99:1279\u20131283","journal-title":"Am J Cardiol"},{"key":"163_CR18","first-page":"73","volume-title":"Principles of exercise testing and interpretation","author":"K Wasserman","year":"1986","unstructured":"Wasserman K, Hansen JE, Sue DY et al (1986) Principles of exercise testing and interpretation. Lea & Febiger, Philadelphia, pp 73\u201375"},{"key":"163_CR19","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1093\/oxfordjournals.eurheartj.a059837","volume":"12","author":"A Cohen-Solal","year":"1991","unstructured":"Cohen-Solal A, Zannad F, Kayanakis JG et al (1991) Multicentre study of the determination of peak oxygen uptake and ventilatory threshold during bicycle in chronic heart failure. Eur Heart J 12:1055\u20131063","journal-title":"Eur Heart J"},{"key":"163_CR20","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/S0002-8703(03)00100-5","volume":"145","author":"A Mezzani","year":"2003","unstructured":"Mezzani A, Corra U, Bosimini E et al (2003) Contribution of peak respiratory exchange ratio to peak VO2 prognostic reliability in patients with chronic heart failure and severely reduced exercise capacity. Am Heart J 145:1102\u20131107","journal-title":"Am Heart J"},{"key":"163_CR21","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0894-7317(89)80013-6","volume":"2","author":"NB Schiller","year":"1989","unstructured":"Schiller NB, Shah PM, Crawford M et al (1989) Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of echocardiography committee on standards, subcommittee on quantitation of two-dimensional echocardiograms. J Am Soc Echocardiogr 2:358\u2013367","journal-title":"J Am Soc Echocardiogr"},{"key":"163_CR22","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1067\/mhj.2002.121264","volume":"143","author":"S Baldasseroni","year":"2002","unstructured":"Baldasseroni S, Opasich C, Gorini M et al (2002) Left bundle branch block is associated with increased 1-year sudden and total mortality rate in 5517 outpatients with congestive heart failure: a report from the Italian network on congestive heart failure. Am Heart J 143:398\u2013405","journal-title":"Am Heart J"},{"key":"163_CR23","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1093\/eurheartj\/ehm262","volume":"28","author":"F Tabrizi","year":"2007","unstructured":"Tabrizi F, Englund A, Rosenqvist M et al (2007) Influence of left bundle branch block on long-term mortality in a population with heart failure. Eur Heart J 28:2449\u20132455","journal-title":"Eur Heart J"},{"key":"163_CR24","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1016\/j.jacc.2003.10.065","volume":"43","author":"AM Duncan","year":"2004","unstructured":"Duncan AM, Darrel PF, Derek GG et al (2004) Limitation of exercise tolerance in chronic heart failure: distinct effects of left bundle\u2014branch block and coronary artery disease. J Am Coll Cardiol 43:1524\u20131531","journal-title":"J Am Coll Cardiol"},{"key":"163_CR25","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1067\/mhj.2001.113215","volume":"141","author":"AS Maisel","year":"2001","unstructured":"Maisel AS, Koon J, Krishnaswamy P et al (2001) Utility of B-natriuretic peptide as a rapid, point-of-care test for screening patients undergoing echocardiography to determine left ventricular dysfunction. Am Heart J 141:367\u2013374","journal-title":"Am Heart J"},{"key":"163_CR26","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.ahj.2003.10.026","volume":"147","author":"U Corr\u00e0","year":"2004","unstructured":"Corr\u00e0 U, Mezzani A, Bosimini E et al (2004) Limited predictive value of cardiopulomonary exercise indices in patients with moderate chronic heart failure treated with carvedilol. Am Heart J 147:553\u2013560","journal-title":"Am Heart J"},{"key":"163_CR27","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1067\/mhj.2001.115796","volume":"142","author":"M Cicoira","year":"2001","unstructured":"Cicoira M, Davos CH, Florea V et al (2001) Chronic heart failure in the very elderly: clinical status, survival, and prognostic factors in 188 patients more than 70\u00a0years old. Am Heart J 142:174\u2013180","journal-title":"Am Heart J"},{"key":"163_CR28","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1136\/heart.83.2.147","volume":"83","author":"LC Davies","year":"2000","unstructured":"Davies LC, Francis DP, Piepoli M et al (2000) Chronic heart failure in the elderly: value of cardiopulmonary exercise testing in risk stratification. Heart 83:147\u2013151","journal-title":"Heart"},{"key":"163_CR29","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1136\/heart.88.3.239","volume":"88","author":"M Mejhert","year":"2002","unstructured":"Mejhert M, Linder-Klingsell E, Edner M et al (2002) Ventilatory variables are strong prognostic markers in elderly patients with heart failure. Heart 88:239\u2013243","journal-title":"Heart"},{"key":"163_CR30","first-page":"343","volume":"5","author":"AB Scardovi","year":"2004","unstructured":"Scardovi AB (2004) Clinical applications of brain natriuretic peptide testing. Ital Heart J 5:343\u2013356","journal-title":"Ital Heart J"},{"key":"163_CR31","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0735-1097(00)01157-8","volume":"37","author":"V Cheng","year":"2001","unstructured":"Cheng V, Kazanagra R, Garcia A et al (2001) A rapid bedside test for B-type peptide predicts treatment outcomes in patients admitted for decompensated heart failure: a pilot study. J Am Coll Cardiol 37:386\u2013391","journal-title":"J Am Coll Cardiol"},{"key":"163_CR32","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S0735-1097(02)02032-6","volume":"40","author":"S Kruger","year":"2002","unstructured":"Kruger S, Graf J, Kunz D et al (2002) Brain natriuretic peptide levels predict functional capacity in patients with chronic heart failure. J Am Coll Cardiol 40:718\u2013722","journal-title":"J Am Coll Cardiol"},{"key":"163_CR33","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.euje.2005.12.009","volume":"8","author":"AB Scardovi","year":"2007","unstructured":"Scardovi AB, Coletta C, Aspromonte N et al (2007) Brain natriuretic peptide plasma level is a reliable indicator of advanced diastolic dysfunction in patients with chronic heart failure. Eur J Echocardiogr 8:30\u201336","journal-title":"Eur J Echocardiogr"},{"key":"163_CR34","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.jacc.2003.08.046","volume":"43","author":"RW Troughton","year":"2004","unstructured":"Troughton RW, Prior DL, Pereira JJ et al (2004) Plasma B-type natriuretic peptide levels in systolic heart failure. J Am Coll Cardiol 43:416\u2013422","journal-title":"J Am Coll Cardiol"},{"key":"163_CR35","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1161\/01.CIR.101.24.2803","volume":"101","author":"FX Kleber","year":"2000","unstructured":"Kleber FX, Vietzke G, Wernecke KD et al (2000) Impairment of ventilatory efficiency in heart failure. Prognostic impact. Circulation 101:2803\u20132809","journal-title":"Circulation"},{"key":"163_CR36","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ahj.2003.07.014","volume":"147","author":"R Arena","year":"2004","unstructured":"Arena R, Myers J, Aslam SS et al (2004) Peak VO2 and VE\/VCO2 slope in patients with heart failure: a prognostic comparison. Am Heart J 147:354\u2013360","journal-title":"Am Heart J"},{"key":"163_CR37","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1161\/01.CIR.93.5.940","volume":"93","author":"M Piepoli","year":"1996","unstructured":"Piepoli M, Clark AL, Volterrani M et al (1996) Contribution of muscle afferents to the hemodynamic, autonomic and ventilatory responses to exercise in patients with chronic heart failure. Circulation 93:940\u2013952","journal-title":"Circulation"},{"key":"163_CR38","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1161\/01.CIR.100.3.262","volume":"100","author":"K Narkiewicz","year":"1999","unstructured":"Narkiewicz K, Pesek CA, van de Borne PJ et al (1999) Enhanced sympathetic and ventilatory responses to central chemoreflex activation in heart failure. Circulation 100:262\u2013267","journal-title":"Circulation"},{"key":"163_CR39","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1161\/01.CIR.96.8.2586","volume":"96","author":"P Ponikowski","year":"1997","unstructured":"Ponikowski P, Chua TP, Piepoli M et al (1997) Augmented peripheral chemosensitivity as a potential input to baroreflex impairment and autonomic imbalance in chronic heart failure. Circulation 96:2586\u20132594","journal-title":"Circulation"},{"key":"163_CR40","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/0002-9149(92)90202-A","volume":"70","author":"M Metra","year":"1992","unstructured":"Metra M, Dei Cas L, Panina G et al (1992) Exercise hyperventilation chronic congestive heart failure and its relation to functional capacity and hemodynamics. Am J Cardiol 70:622\u2013628","journal-title":"Am J Cardiol"},{"key":"163_CR41","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S0002-8703(98)70121-8","volume":"136","author":"I Reindl","year":"1998","unstructured":"Reindl I, Wernecke KD, Opitz C et al (1998) Impaired ventilatory efficiency in chronic heart failure: possible role of pulmonary vasoconstriction. Am Heart J 136:778\u201385","journal-title":"Am Heart J"},{"key":"163_CR42","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0735-1097(00)01211-0","volume":"37","author":"A Hansen","year":"2001","unstructured":"Hansen A, Haass M, Zugck C et al (2001) Prognostic value of Doppler echocardiographic mitral inflow patterns: implications for risk stratification in patients with chronic congestive heart failure. J Am Coll Cardiol 37:1049\u20131055","journal-title":"J Am Coll Cardiol"},{"key":"163_CR43","first-page":"430","volume":"72","author":"C Haug","year":"1994","unstructured":"Haug C, Metzele A, Steffgen J et al (1994) Increased brain natriuretic peptide and atrial natriuretic peptide plasma concentrations in dialysis-dependent chronic renal failure and in patients with elevated left ventricular filling pressure. J Clin Invest 72:430\u2013434","journal-title":"J Clin Invest"},{"key":"163_CR44","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.ejheart.2004.01.008","volume":"6","author":"P Bettencourt","year":"2004","unstructured":"Bettencourt P (2004) NT-pro BNP and BNP: biomarkers for heart failure management. Eur J Heart Fail 6:359\u2013363","journal-title":"Eur J Heart Fail"}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-008-0163-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11739-008-0163-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-008-0163-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T21:21:29Z","timestamp":1559424089000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11739-008-0163-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,17]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["163"],"URL":"https:\/\/doi.org\/10.1007\/s11739-008-0163-x","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"value":"1828-0447","type":"print"},{"value":"1970-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,17]]}}}