{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:49:10Z","timestamp":1761155350174},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,2,25]],"date-time":"2010-02-25T00:00:00Z","timestamp":1267056000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1007\/s11739-010-0356-y","type":"journal-article","created":{"date-parts":[[2010,2,24]],"date-time":"2010-02-24T15:37:50Z","timestamp":1267025870000},"page":"127-134","source":"Crossref","is-referenced-by-count":10,"title":["Carotid intima-media thickness and bone turnover: the role of C-terminal telopeptide of type I collagen"],"prefix":"10.1007","volume":"5","author":[{"given":"Christian","family":"Leli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonella","family":"Pasqualini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Vaudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Gaggioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Maria","family":"Scarponi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elmo","family":"Mannarino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,2,25]]},"reference":[{"key":"356_CR1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1007\/s00198-007-0539-1","volume":"19","author":"M Naves","year":"2008","unstructured":"Naves M, Rodr\u00edguez-Garc\u00eda M, D\u00edaz-L\u00f3pez JB et al (2008) Progression of vascular calcifications associated with greater bone loss and increased bone fractures. Osteoporos Int 19:1161\u20131166","journal-title":"Osteoporos Int"},{"key":"356_CR2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1359\/jbmr.070903","volume":"23","author":"P Szulc","year":"2008","unstructured":"Szulc P, Kiel DP, Delmas PD (2008) Calcifications in the abdominal aorta predict fractures in men: MINOS study. J Bone Miner Res 23:95\u2013102","journal-title":"J Bone Miner Res"},{"key":"356_CR3","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/ncpcardio1163","volume":"5","author":"E Groot de","year":"2008","unstructured":"de Groot E, van Leuven SI, Duivenvoorden R et al (2008) Measurement of carotid intima-media thickness to assess progression and regression of atherosclerosis. Nat Clin Pract Cardiovasc Med 5:280\u2013288","journal-title":"Nat Clin Pract Cardiovasc Med"},{"key":"356_CR4","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1291\/hypres.31.1191","volume":"31","author":"H Sumino","year":"2008","unstructured":"Sumino H, Ichikawa S, Kasama S et al (2008) Relationship between carotid atherosclerosis and lumbar spine bone mineral density in postmenopausal women. Hypertens Res 31:1191\u20131197","journal-title":"Hypertens Res"},{"key":"356_CR5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ijcard.2007.09.002","volume":"131","author":"GO Tekin","year":"2008","unstructured":"Tekin GO, Kekilli E, Yagmur J et al (2008) Evaluation of cardiovascular risk factors and bone mineral density in post menopausal women undergoing coronary angiography. Int J Cardiol 131:66\u201369","journal-title":"Int J Cardiol"},{"key":"356_CR6","doi-asserted-by":"crossref","first-page":"146","DOI":"10.5414\/CNP63146","volume":"63","author":"CM Shanahan","year":"2005","unstructured":"Shanahan CM (2005) Mechanisms of vascular calcification in renal disease. Clin Nephrol 63:146\u2013157","journal-title":"Clin Nephrol"},{"key":"356_CR7","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1093\/ije\/31.4.737","volume":"31","author":"LL Demer","year":"2002","unstructured":"Demer LL (2002) Vascular calcification and osteoporosis: inflammatory responses to oxidized lipids. Int J Epidemiol 31:737\u2013741","journal-title":"Int J Epidemiol"},{"key":"356_CR8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/MCO.0b013e3282f2f4dd","volume":"11","author":"ED Michos","year":"2008","unstructured":"Michos ED, Melamed ML (2008) Vitamin D and cardiovascular disease risk. Curr Opin Clin Nutr Metab Care 11:7\u201312","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"356_CR9","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00198-006-0282-z","volume":"18","author":"LC Hofbauer","year":"2007","unstructured":"Hofbauer LC, Brueck CC, Shanahan CM et al (2007) Vascular calcification and osteoporosis-from clinical observation towards molecular understanding. Osteoporos Int 18:251\u2013259","journal-title":"Osteoporos Int"},{"key":"356_CR10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF03256280","volume":"12","author":"P Garnero","year":"2008","unstructured":"Garnero P (2008) Biomarkers for osteoporosis management: utility in diagnosis, fracture risk prediction and therapy monitoring. Mol Diagn Ther 12:157\u2013170","journal-title":"Mol Diagn Ther"},{"key":"356_CR11","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00774-003-0460-4","volume":"22","author":"R Okabe","year":"2004","unstructured":"Okabe R, Inaba M, Nakatsuka K et al (2004) Significance of serum CrossLaps as a predictor of changes in bone mineral density during estrogen replacement therapy; comparison with serum carboxyterminal telopeptide of type I collagen and urinary deoxypyridinoline. J Bone Miner Metab 22:127\u2013131","journal-title":"J Bone Miner Metab"},{"key":"356_CR12","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1002\/jbmr.5650111021","volume":"11","author":"P Garnero","year":"1996","unstructured":"Garnero P, Hausherr E, Chapuy MC et al (1996) Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study. J Bone Miner Res 11:1531\u20131538","journal-title":"J Bone Miner Res"},{"key":"356_CR13","first-page":"S1","volume":"12","author":"JP Brown","year":"2002","unstructured":"Brown JP, Josse RG (2002) Scientific Advisory Council of the Osteoporosis Society of Canada. 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. CMAJ 12:S1\u2013S34","journal-title":"CMAJ"},{"key":"356_CR14","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1097\/00004872-200310000-00001","volume":"21","author":"R Cifkova","year":"2003","unstructured":"Cifkova R, Erdine S, Fagard R et al (2003) ESH\/ESC Hypertension Guidelines Committee. Practice guidelines for primary care physicians: 2003 ESH\/ESC hypertension guidelines. J Hypertens 21:1779\u20131786","journal-title":"J Hypertens"},{"key":"356_CR15","doi-asserted-by":"crossref","unstructured":"American Diabetes Association (2008) Diagnosis and classification of diabetes mellitus. Diabetes Care 31:S55\u2013S60","DOI":"10.2337\/dc08-S055"},{"key":"356_CR16","unstructured":"Adult Treatment Panel III (2002) Final report. Circulation 106:3143\u20133421"},{"key":"356_CR17","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/MED.0b013e328317ca6c","volume":"15","author":"BW Hollis","year":"2008","unstructured":"Hollis BW (2008) Assessment of vitamin D status and definition of a normal circulating range of 25-hydroxyvitamin D. Curr Opin Endocrinol Diabetes Obes 15:489\u2013494","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"356_CR18","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1161\/CIRCULATIONAHA.106.628875","volume":"115","author":"MW Lorenz","year":"2007","unstructured":"Lorenz MW, Markus HS, Bots ML et al (2007) Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 115:459\u2013467","journal-title":"Circulation"},{"key":"356_CR19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00198-008-0633-z","volume":"20","author":"J Tamaki","year":"2009","unstructured":"Tamaki J, Iki M, Hirano Y et al (2009) Low bone mass is associated with carotid atherosclerosis in postmenopausal women: the Japanese population-based osteoporosis (JPOS) cohort study. Osteoporos Int 20:53\u201360","journal-title":"Osteoporos Int"},{"key":"356_CR20","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1447-0756.2008.00868.x","volume":"35","author":"LK Trento","year":"2009","unstructured":"Trento LK, Pietropolli A, Ticconi C et al (2009) Role of type I collagen C telopeptide, bone-specific alkaline phosphatase and osteocalcin in the assessment of bone status in postmenopausal women. J Obstet Gynaecol Res 35:152\u2013159","journal-title":"J Obstet Gynaecol Res"},{"key":"356_CR21","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.maturitas.2008.05.003","volume":"60","author":"HJ Choi","year":"2008","unstructured":"Choi HJ, Im JA, Kim SH (2008) Changes in bone markers after once-weekly low-dose alendronate in postmenopausal women with moderate bone loss. Maturitas 60:170\u2013176","journal-title":"Maturitas"},{"key":"356_CR22","doi-asserted-by":"crossref","unstructured":"Binkley N, Silverman SL, Simonelli C et al (2009) Monthly ibandronate suppresses serum CTX-I within 3\u00a0days and maintains a monthly fluctuating pattern of suppression. Osteoporos Int (Jan 15)","DOI":"10.1007\/s00198-008-0827-4"},{"key":"356_CR23","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.metabol.2007.10.005","volume":"57","author":"D Siepi","year":"2008","unstructured":"Siepi D, Marchesi S, Vaudo G et al (2008) Preclinical vascular damage in white postmenopausal women: the relevance of osteoprotegerin. Metabolism 57:321\u2013325","journal-title":"Metabolism"},{"key":"356_CR24","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1179\/016164104225014157","volume":"26","author":"B Erdogan","year":"2004","unstructured":"Erdogan B, Aslan E, Bagis T et al (2004) Intima-media thickness of the carotid arteries is related to serum osteoprotegerin levels in healthy postmenopausal women. Neurol Res 26:658\u2013661","journal-title":"Neurol Res"},{"key":"356_CR25","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.1002\/art.11327","volume":"48","author":"M Nagata-Sakurai","year":"2003","unstructured":"Nagata-Sakurai M, Inaba M, Goto H et al (2003) Inflammation and bone resorption as independent factors of accelerated arterial wall thickening in patients with rheumatoid arthritis. Arthritis Rheum 48:3061\u20133067","journal-title":"Arthritis Rheum"},{"key":"356_CR26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1161\/01.RES.0000026421.61398.F2","volume":"91","author":"A Shioi","year":"2002","unstructured":"Shioi A, Katagi M, Okuno Y et al (2002) Induction of bone-type alkaline phosphatase in human vascular smooth muscle cells: roles of tumor necrosis factor-alpha and oncostatin M derived from macrophages. Circ Res 91:9\u201316","journal-title":"Circ Res"},{"key":"356_CR27","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1161\/hq1201.100229","volume":"21","author":"CR Dhore","year":"2001","unstructured":"Dhore CR, Cleutjens JP, Lutgens E et al (2001) Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 21:1998\u20132003","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"356_CR28","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1172\/JCI116391","volume":"91","author":"K Bostr\u00f6m","year":"1993","unstructured":"Bostr\u00f6m K, Watson KE, Horn S et al (1993) Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest 91:1800\u20131809","journal-title":"J Clin Invest"},{"key":"356_CR29","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1172\/JCI117246","volume":"93","author":"CM Shanahan","year":"1994","unstructured":"Shanahan CM, Cary NR, Metcalfe JC et al (1994) High expression of genes for calcification-regulating proteins in human atherosclerotic plaques. J Clin Invest 93:2393\u20132402","journal-title":"J Clin Invest"},{"key":"356_CR30","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1365-2141.1999.01491.x","volume":"106","author":"HM Massey","year":"1999","unstructured":"Massey HM, Flanagan AM (1999) Human osteoclasts derive from CD14- positive monocytes. Br J Haematol 106:167\u2013170","journal-title":"Br J Haematol"},{"key":"356_CR31","doi-asserted-by":"crossref","first-page":"7260","DOI":"10.1073\/pnas.87.18.7260","volume":"87","author":"N Udagawa","year":"1990","unstructured":"Udagawa N, Takahashi N, Akatsu T et al (1990) Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc Natl Acad Sci USA 87:7260\u20137264","journal-title":"Proc Natl Acad Sci USA"},{"key":"356_CR32","doi-asserted-by":"crossref","unstructured":"Busti C, Falcinelli E, Momi S et al (2009) Matrix metalloproteinases and peripheral arterial disease. Intern Emerg Med (Sep 24)","DOI":"10.1007\/s11739-009-0308-6"},{"key":"356_CR33","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00198-005-0017-6","volume":"17","author":"XH Luo","year":"2006","unstructured":"Luo XH, Guo LJ, Shan PF et al (2006) Relationship of circulating MMP-2, MMP-1, and TIMP-1 levels with bone biochemical markers and bone mineral density in postmenopausal Chinese women. Osteoporos Int 17:521\u2013526","journal-title":"Osteoporos Int"},{"key":"356_CR34","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00198-003-1550-9","volume":"15","author":"P Pennisi","year":"2004","unstructured":"Pennisi P, Signorelli SS, Riccobene S et al (2004) Low bone density and abnormal bone turnover in patients with atherosclerosis of peripheral vessels. Osteoporos Int 15:389\u2013395","journal-title":"Osteoporos Int"},{"key":"356_CR35","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.cca.2008.03.020","volume":"393","author":"M Herrmann","year":"2008","unstructured":"Herrmann M, Seibel MJ (2008) The amino- and carboxyterminal cross-linked telopeptides of collagen type I, NTX-I and CTX-I: a comparative review. Clin Chim Acta 393:57\u201375","journal-title":"Clin Chim Acta"},{"key":"356_CR36","doi-asserted-by":"crossref","unstructured":"Linnebur SA, Vondracek SF, van de Griend JP et al (2007) Prevalence of vitamin D insufficiency in elderly ambulatory outpatients in Denver, Colorado. Am J Geriatr Pharmacother 5:1\u20138","DOI":"10.1016\/j.amjopharm.2007.03.005"},{"key":"356_CR37","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1161\/01.CIR.96.6.1755","volume":"96","author":"KE Watson","year":"1997","unstructured":"Watson KE, Abrolat ML, Malone LL et al (1997) Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation 96:1755\u20131760","journal-title":"Circulation"},{"key":"356_CR38","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1093\/ije\/19.3.559","volume":"19","author":"R Scragg","year":"1990","unstructured":"Scragg R, Jackson R, Holdaway IM et al (1990) Myocardial infarction is inversely associated with plasma 25-hydroxyvitamin D3 levels: a community-based study. Int J Epidemiol 19:559\u2013563","journal-title":"Int J Epidemiol"},{"key":"356_CR39","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1161\/01.STR.0000195184.24297.c1","volume":"37","author":"KE Poole","year":"2006","unstructured":"Poole KE, Loveridge N, Barker PJ et al (2006) Reduced vitamin D in acute stroke. Stroke 37:243\u2013245","journal-title":"Stroke"},{"key":"356_CR40","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1007\/s001980070002","volume":"6","author":"PD Delmas","year":"2000","unstructured":"Delmas PD, Eastell R, Garnero P et al (2000) The use of biochemical markers of bone turnover in osteoporosis. Osteoporos Int 6:S2\u2013S17","journal-title":"Osteoporos Int"},{"key":"356_CR41","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1093\/jn\/137.4.930","volume":"137","author":"AZ Budek","year":"2007","unstructured":"Budek AZ, Hoppe C, Michaelsen KF et al (2007) Associations of total, dairy, and meat protein with markers for bone turnover in healthy, prepubertal boys. J Nutr 137:930\u2013934","journal-title":"J Nutr"}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-010-0356-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11739-010-0356-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-010-0356-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T21:21:33Z","timestamp":1559424093000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11739-010-0356-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,25]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["356"],"URL":"https:\/\/doi.org\/10.1007\/s11739-010-0356-y","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"value":"1828-0447","type":"print"},{"value":"1970-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,25]]}}}