{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T22:15:59Z","timestamp":1773440159678,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,6,16]],"date-time":"2015-06-16T00:00:00Z","timestamp":1434412800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s11739-015-1263-z","type":"journal-article","created":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T09:08:44Z","timestamp":1434359324000},"page":"19-30","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Contrast-enhanced ultrasonography to diagnose complicated acute cholecystitis"],"prefix":"10.1007","volume":"11","author":[{"given":"Elisabetta","family":"Sagrini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Pecorelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Pettinari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Cucchetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Stefanini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Bolondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Piscaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,6,16]]},"reference":[{"key":"1263_CR1","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/S0039-6060(99)70122-4","volume":"126","author":"LT Merriam","year":"1999","unstructured":"Merriam LT, Kanaan SA, Dawes LG et al (1999) Gangrenous cholecystitis: analysis of risk factors and experience with laparoscopic cholecystectomy. Surgery 126:680\u2013685","journal-title":"Surgery"},{"key":"1263_CR2","doi-asserted-by":"crossref","first-page":"E30","DOI":"10.1177\/000313481207800120","volume":"78","author":"BK Jain","year":"2012","unstructured":"Jain BK, Prasad D, Mohanty D, Garg PK, Diwaker P, Agarwal V (2012) Gallbladder perforation: a great masquerader. Am Surg 78:E30\u2013E32","journal-title":"Am Surg"},{"key":"1263_CR3","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1007\/s00464-012-2206-7","volume":"26","author":"B Navez","year":"2012","unstructured":"Navez B, Ungureanu F, Michiels M et al (2012) Surgical management of acute cholecystitis: results of a 2-year prospective multicenter survey in Belgium. Surg Endosc 26:2436\u20132445","journal-title":"Surg Endosc"},{"key":"1263_CR4","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s00261-010-9612-x","volume":"36","author":"CH Wu","year":"2011","unstructured":"Wu CH, Chen CC, Wang CJ et al (2011) Discrimination of gangrenous from uncomplicated acute cholecystitis: accuracy of CT findings. Abdom Imaging 36:174\u2013178","journal-title":"Abdom Imaging"},{"key":"1263_CR5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2214\/ajr.178.2.1780275","volume":"178","author":"GL Bennett","year":"2002","unstructured":"Bennett GL, Rusinek H, Lisi V et al (2002) CT findings in acute gangrenous cholecystitis. AJR Am J Roentgenol 178:275\u2013281","journal-title":"AJR Am J Roentgenol"},{"key":"1263_CR6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1055\/s-0031-1281676","volume":"33","author":"F Piscaglia","year":"2011","unstructured":"Piscaglia F, Nolsoe C, Dietrich CF et al (2011) The EFSUMB guidelines and recommendations on the clinical practice of contrast enhanced ultrasound (CEUS): update 2011 on non-hepatic applications. Ultraschall Med 33:33\u201359","journal-title":"Ultraschall Med"},{"key":"1263_CR7","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/j.ajem.2013.04.034","volume":"31","author":"S Tang","year":"2013","unstructured":"Tang S, Wang Y (2013) Contrast-enhanced ultrasonography to diagnose gallbladder perforation. Am J Emerg Med 31:1240\u20131243","journal-title":"Am J Emerg Med"},{"key":"1263_CR8","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1007\/s00534-012-0548-0","volume":"19","author":"M Yokoe","year":"2012","unstructured":"Yokoe M, Takada T, Strasberg SM et al (2012) New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo guidelines. J Hepatobiliaty Pancreat Sci 19:578\u2013585","journal-title":"J Hepatobiliaty Pancreat Sci"},{"key":"1263_CR9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ultrasmedbio.2012.09.002","volume":"39","author":"M Claudon","year":"2013","unstructured":"Claudon M, Dietrich CF, Choi BI et al (2013) Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) in the liver\u2014update 2012: a WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultrasound Med Biol 39:187\u2013210","journal-title":"Ultrasound Med Biol"},{"key":"1263_CR10","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4329\/wjr.v1.i1.37","volume":"1","author":"HX Xu","year":"2009","unstructured":"Xu HX (2009) Contrast-enhanced ultrasound in the biliary system: potential uses and indications. World J Radiol 1:37\u201344","journal-title":"World J Radiol"},{"key":"1263_CR11","doi-asserted-by":"crossref","first-page":"7832","DOI":"10.3748\/wjg.v12.i48.7832","volume":"12","author":"H Derici","year":"2006","unstructured":"Derici H, Kara C, Bozdag AD, Nazli O, Tansug T, Akca E (2006) Diagnosis and treatment of gallbladder perforation. World J Gastroenterol 12:7832\u20137836","journal-title":"World J Gastroenterol"},{"key":"1263_CR12","first-page":"1275","volume":"48","author":"A Bedirli","year":"2001","unstructured":"Bedirli A, Sakrak O, Sozuer EM, Kerek M, Guler I (2001) Factors effecting the complications in the natural history of acute cholecystitis. Hepatogastroenterology 48:1275\u20131278","journal-title":"Hepatogastroenterology"},{"key":"1263_CR13","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0002-9610(01)00702-4","volume":"182","author":"M Schafer","year":"2001","unstructured":"Schafer M, Krahenbuhl L, Buchler MW (2001) Predictive factors for the type of surgery in acute cholecystitis. Am J Surg 182:291\u2013297","journal-title":"Am J Surg"},{"key":"1263_CR14","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1007\/s00464-013-2921-8","volume":"27","author":"G Borzellino","year":"2013","unstructured":"Borzellino G, Steccanella F, Mantovani W, Genna M (2013) Predictive factors for the diagnosis of severe acute cholecystitis in an emergency setting. Surg Endosc 27:3388\u20133395","journal-title":"Surg Endosc"},{"key":"1263_CR15","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1097\/01.mcg.0000135898.68155.88","volume":"38","author":"S Contini","year":"2004","unstructured":"Contini S, Corradi D, Busi N, Alessandri L, Pezzarossa A, Scarpignato C (2004) Can gangrenous cholecystitis be prevented?: a plea against a \u201cwait and see\u201d attitude. J Clin Gastroenterol 38:710\u2013716","journal-title":"J Clin Gastroenterol"},{"key":"1263_CR16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2214\/ajr.152.2.289","volume":"152","author":"JF Simeone","year":"1989","unstructured":"Simeone JF, Brink JA, Mueller PR et al (1989) The sonographic diagnosis of acute gangrenous cholecystitis: importance of the Murphy sign. AJR Am J Roentgenol 152:289\u2013290","journal-title":"AJR Am J Roentgenol"},{"key":"1263_CR17","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1046\/j.1440-1622.2000.01851.x","volume":"70","author":"DR Hunt","year":"2000","unstructured":"Hunt DR, Chu FC (2000) Gangrenous cholecystitis in the laparoscopic era. Aust N Z J Surg 70:428\u2013430","journal-title":"Aust N Z J Surg"},{"key":"1263_CR18","doi-asserted-by":"crossref","first-page":"603","DOI":"10.7863\/jum.1991.10.11.603","volume":"10","author":"SA Teefey","year":"1991","unstructured":"Teefey SA, Baron RL, Radke HM, Bigler SA (1991) Gangrenous cholecystitis: new observations on sonography. J Ultrasound Med 10:603\u2013606","journal-title":"J Ultrasound Med"},{"key":"1263_CR19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1148\/radiology.134.1.7350604","volume":"134","author":"RA Kane","year":"1980","unstructured":"Kane RA (1980) Ultrasonographic diagnosis of gangrenous cholecystitis and empyema of the gallbladder. Radiology 134:191\u2013194","journal-title":"Radiology"},{"key":"1263_CR20","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1148\/radiology.148.1.6856839","volume":"148","author":"RB Jeffrey","year":"1983","unstructured":"Jeffrey RB, Laing FC, Wong W, Callen PW (1983) Gangrenous cholecystitis: diagnosis by ultrasound. Radiology 148:219\u2013221","journal-title":"Radiology"},{"key":"1263_CR21","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/jcu.1870160512","volume":"16","author":"WK Chau","year":"1988","unstructured":"Chau WK, Na AT, Feng TT, Li YB (1988) Ultrasound diagnosis of perforation of the gallbladder: real-time application and the demonstration of a new sonographic sign. J Clin Ultrasound 16:358\u2013360","journal-title":"J Clin Ultrasound"},{"key":"1263_CR22","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jcu.10071","volume":"30","author":"BP Sood","year":"2002","unstructured":"Sood BP, Kalra N, Gupta S et al (2002) Role of sonography in the diagnosis of gallbladder perforation. J Clin Ultrasound 30:270\u2013274","journal-title":"J Clin Ultrasound"},{"key":"1263_CR23","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.ultrasmedbio.2006.05.031","volume":"32","author":"F Piscaglia","year":"2006","unstructured":"Piscaglia F, Bolondi L (2006) The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations. Ultrasound Med Biol 32:1369\u20131375","journal-title":"Ultrasound Med Biol"},{"key":"1263_CR24","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00261-005-0393-6","volume":"31","author":"Y Kumagai","year":"2006","unstructured":"Kumagai Y, Kotanagi H, Ishida H et al (2006) Gallbladder adenoma: report of a case with emphasis on contrast-enhanced US findings. Abdom Imaging 31:449\u2013452","journal-title":"Abdom Imaging"},{"issue":"3","key":"1263_CR25","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3233\/CH-121651","volume":"55","author":"SG Zheng","year":"2013","unstructured":"Zheng SG, Xu HX, Liu LN et al (2013) Contrast-enhanced ultrasound versus conventional ultrasound in the diagnosis of polypoid lesion of gallbladder: a multi-center study of dynamic microvascularization. Clin Hemorheol Microcirc 55(3):359\u2013374","journal-title":"Clin Hemorheol Microcirc"},{"issue":"4","key":"1263_CR26","first-page":"326","volume":"14","author":"Z Sparchez","year":"2012","unstructured":"Sparchez Z, Radu P (2012) Role of CEUS in the diagnosis of gallbladder disease. Med Ultrason 14(4):326\u2013330","journal-title":"Med Ultrason"},{"issue":"1","key":"1263_CR27","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00330-009-1538-8","volume":"20","author":"XH Xie","year":"2010","unstructured":"Xie XH, Xu HX, Xie XY et al (2010) Differential diagnosis between benign and malignant gallbladder diseases with real-time contrast-enhanced ultrasound. Eur Radiol 20(1):239\u2013248","journal-title":"Eur Radiol"},{"issue":"10","key":"1263_CR28","doi-asserted-by":"crossref","first-page":"e48371","DOI":"10.1371\/journal.pone.0048371","volume":"7","author":"LN Liu","year":"2012","unstructured":"Liu LN, Xu HX, Lu MD et al (2012) Contrast-enhanced ultrasound in the diagnosis of gallbladder diseases: a multi-center experience. PLoS One 7(10):e48371","journal-title":"PLoS One"},{"key":"1263_CR29","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.ultrasmedbio.2006.09.003","volume":"33","author":"T Inoue","year":"2007","unstructured":"Inoue T, Kitano M, Kudo M et al (2007) Diagnosis of gallbladder diseases by contrast-anhanced phase-inversion harmonic ultrasonography. Ultrasound Med Biol 33:353\u2013361","journal-title":"Ultrasound Med Biol"},{"key":"1263_CR30","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ejrad.2006.09.006","volume":"61","author":"B Adamietz","year":"2007","unstructured":"Adamietz B, Wenkel E, Uder M et al (2007) Contrast enhanced sonography of the gallbladder: a tool in the diagnosis of cholecystitis? Eur J Radiol 61:262\u2013266","journal-title":"Eur J Radiol"},{"issue":"516","key":"1263_CR31","first-page":"e515","volume":"30","author":"PM Zechner","year":"2012","unstructured":"Zechner PM, Rienmuller S, Dorr K, Genger C, Wurzer H (2012) Contrast-enhanced ultrasound detects gallbladder perforation in a patient with acute abdominal pain. Am J Emerg Med 30(516):e515\u2013e516","journal-title":"Am J Emerg Med"},{"key":"1263_CR32","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s10396-011-0316-9","volume":"38","author":"YTT Yashima","year":"2011","unstructured":"Yashima YTT, Nakahara S, Ishida K, Nakata R, Isayama H, Koike K (2011) Contrast-enhanced ultrasonographic image of gangrenous gallbladder. J Med Ultrason 38:239\u2013241","journal-title":"J Med Ultrason"}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-015-1263-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11739-015-1263-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-015-1263-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T12:24:12Z","timestamp":1599135852000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11739-015-1263-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,16]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["1263"],"URL":"https:\/\/doi.org\/10.1007\/s11739-015-1263-z","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"value":"1828-0447","type":"print"},{"value":"1970-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,16]]}}}