{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:44:24Z","timestamp":1767141864196,"version":"build-2238731810"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T00:00:00Z","timestamp":1456963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"None","award":["None"],"award-info":[{"award-number":["None"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1007\/s11739-016-1415-9","type":"journal-article","created":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T05:20:19Z","timestamp":1456982419000},"page":"803-807","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Vitamin D deficiency in patients with either rheumatic diseases or inflammatory bowel diseases on biologic therapy"],"prefix":"10.1007","volume":"11","author":[{"given":"Vincenzo","family":"Bruzzese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Zullo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Piacchianti Diamanti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Ridola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Lorenzetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Marrese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Palma","family":"Scolieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"De Francesco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Migliore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Lagan\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,3,3]]},"reference":[{"key":"1415_CR1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s11926-008-0020-y","volume":"10","author":"N Khazai","year":"2008","unstructured":"Khazai N, Judd SE, Tangpricha V (2008) Calcium and vitamin D: skeletal and extraskeletal health. Curr Rheumatol Rep 10:110\u2013117","journal-title":"Curr Rheumatol Rep"},{"key":"1415_CR2","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1210\/jc.2011-0385","volume":"96","author":"MF Holick","year":"2011","unstructured":"Holick MF, Binkley NC, Bischoff-Ferrari HA et al (2011) Evaluation, treatment, and prevention of vitamin d deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 96:1911\u20131930","journal-title":"J Clin Endocrinol Metab"},{"key":"1415_CR3","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.autrev.2011.08.003","volume":"11","author":"M Cutolo","year":"2011","unstructured":"Cutolo M, Pizzorni C, Sulli A (2011) Vitamin D endocrine system involvement in autoimmune rheumatic diseases. Autoimm Rev 11:84\u201387","journal-title":"Autoimm Rev"},{"key":"1415_CR4","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/s12016-012-8342-y","volume":"45","author":"N Agmon-Levin","year":"2013","unstructured":"Agmon-Levin N, Ramit Maoz ET, Shoenfeld SY (2013) Vitamin D in systemic and organ-specific autoimmune diseases. Clinic Rev Allerg Immunol 45:256\u2013266","journal-title":"Clinic Rev Allerg Immunol"},{"key":"1415_CR5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/BOR.0b013e328336ec24","volume":"22","author":"M Cutolo","year":"2010","unstructured":"Cutolo M (2010) Hormone therapy in rheumatic diseases. Curr Opin Rheumatol 22:257\u2013263","journal-title":"Curr Opin Rheumatol"},{"key":"1415_CR6","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1136\/ard.2008.093476","volume":"68","author":"M Cutolo","year":"2009","unstructured":"Cutolo M, Otsa K, Paolino S et al (2009) Vitamin D involvement in rheumatoid arthritis and systemic lupus erythaematosus. Ann Rheum Dis 68:446\u2013447","journal-title":"Ann Rheum Dis"},{"key":"1415_CR7","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1111\/j.1572-0241.2007.01753.x","volume":"103","author":"WD Leslie","year":"2008","unstructured":"Leslie WD, Miller N, Rogala L, Bernstein CN (2008) Vitamin D status and bone density in recently diagnosed inflammatory bowel disease: the Manitoba IBD Cohort Study. Am J Gastroenterol 103:1451\u20131459","journal-title":"Am J Gastroenterol"},{"key":"1415_CR8","doi-asserted-by":"publisher","first-page":"470805","DOI":"10.1155\/2015\/470805","volume":"2015","author":"M Ardesia","year":"2015","unstructured":"Ardesia M, Ferlazzo G, Fries W (2015) Vitamin D and inflammatory bowel disease. BioMed Res Int 2015:470805. doi: 10.1155\/2015\/470805","journal-title":"BioMed Res Int"},{"key":"1415_CR9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jsbmb.2005.06.002","volume":"97","author":"E Etten van","year":"2005","unstructured":"van Etten E, Mathieu C (2005) Immunoregulation by 1-25-dihydroxivitamin D3: basic concepts. J Steroid Biochem Mol Biol 97:93\u2013101","journal-title":"J Steroid Biochem Mol Biol"},{"key":"1415_CR10","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/art.25043","volume":"62","author":"EM Colin","year":"2010","unstructured":"Colin EM, Asmawidjaja PS, van Hamburg JP et al (2010) 1-25-dihydroxivitamin D3 modulatesTh17 polarization and interleukin-22 expression by memory T cell from patients with early rheumatoid arthritis. Arthritis Rheum 62:132\u2013142","journal-title":"Arthritis Rheum"},{"key":"1415_CR11","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.4049\/jimmunol.179.3.1634","volume":"179","author":"S Chen","year":"2007","unstructured":"Chen S, Sims GP, Chen XX et al (2007) Modulatory effects of 1-25-dihydroxivitamin D3 on human B cell differentiation. J Immunol 179:1634\u20131647","journal-title":"J Immunol"},{"key":"1415_CR12","first-page":"148","volume":"21","author":"M Cutolo","year":"2003","unstructured":"Cutolo M (2003) Solar light effect on onset\/relapses and circannual\/circadian syptomatology in rheumatoid arthritis. Clin Exp Rheumatol 21:148\u2013150","journal-title":"Clin Exp Rheumatol"},{"key":"1415_CR13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3899\/jrheum.100516","volume":"38","author":"GS Kerr","year":"2011","unstructured":"Kerr GS, Sabahi I, Richards JS et al (2011) Prevalence of vitamin D insufficiency\/deficiency in rheumatoid arthritis and association with disease severity and activity. J Rheumatol 38:53\u201359","journal-title":"J Rheumatol"},{"key":"1415_CR14","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/0961203311422094","volume":"21","author":"CC Mok","year":"2012","unstructured":"Mok CC, Birbingham DJ, Ho LY et al (2012) Vitamin D deficiency as marker of disease activity and damage in systemic lupus erythematosus: a comparison with anti\u2013ds DNA and anti C1q. Lupus 21:36\u201342","journal-title":"Lupus"},{"key":"1415_CR15","first-page":"34","volume":"68","author":"V Hassan","year":"2013","unstructured":"Hassan V, Hassan S, Seyed-Javad P et al (2013) Association between serum 25(OH) Vitamin D concentration and Inflammatory bowel Diseases (IBDs) activity. Med J Malaysia 68:34\u201338","journal-title":"Med J Malaysia"},{"key":"1415_CR16","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/ecco-jcc\/jju004","volume":"9","author":"T Hlavaty","year":"2015","unstructured":"Hlavaty T, Krajcovicova A, Payer J (2015) Vitamin D therapy in inflammatory bowel diseases: who, in what form, and how much? J Crohns Colitis 9:198\u2013209","journal-title":"J Crohns Colitis"},{"key":"1415_CR17","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.autrev.2009.12.001","volume":"9","author":"C Selmi","year":"2010","unstructured":"Selmi C, Tsuneyama K (2010) Nutrition, geoepidemiology, and autoimmunity. Autoimmun Rev 9:267\u2013270","journal-title":"Autoimmun Rev"},{"key":"1415_CR18","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1007\/s10620-015-3710-0","volume":"60","author":"M O\u2019Sullivan","year":"2015","unstructured":"O\u2019Sullivan M (2015) Does vitamin D protect the gut mucosal barrier? Mechanistic insights from experimental colitis. Dig Dis Sci 60:1871\u20131872","journal-title":"Dig Dis Sci"},{"key":"1415_CR19","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/2050640615572176","volume":"3","author":"T Raftery","year":"2015","unstructured":"Raftery T, Martineau AR, Greiller CL et al (2015) Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn\u2019s disease: results from a randomised double-blind placebo-controlled study. United Eur Gastroenterol J 3:294\u2013302","journal-title":"United Eur Gastroenterol J"},{"key":"1415_CR20","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3899\/jrheum.100516","volume":"38","author":"GS Kerr","year":"2011","unstructured":"Kerr GS, Sabahi I, Richards JS et al (2011) Prevalence of vitamin D insufficiency\/deficiency in rheumatoid arthritis and association with disease severity and activity. J Rheumatol 38:53\u201359","journal-title":"J Rheumatol"},{"key":"1415_CR21","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1136\/ard.2010.137265","volume":"70","author":"P Welsh","year":"2011","unstructured":"Welsh P, Peters MJ, McInnes IB et al (2011) Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNF alpha blockade: results from a prospective cohort study. Ann Rheum Dis 70:1165\u20131167","journal-title":"Ann Rheum Dis"},{"key":"1415_CR22","first-page":"31","volume":"6","author":"E Hasan","year":"2012","unstructured":"Hasan E, Olusi S, Al-Awadhi A et al (2012) Effects of rituximab treatment on the serum concentrations of vitamin D and interleukin 2,6,7 and 10 in patients with rheumatoid arthritis. Biologics 6:31\u201335","journal-title":"Biologics"},{"key":"1415_CR23","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/annrheumdis-2013-203419","volume":"73","author":"JS Smolen","year":"2014","unstructured":"Smolen JS, Braun J, Dougados M et al (2014) Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthrtitis, to target: recommendation of an international task force. Ann Rheum Dis 73:6\u201316","journal-title":"Ann Rheum Dis"},{"key":"1415_CR24","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1177\/2050640615590302","volume":"3","author":"J C\u00f4t\u00e9-Daigneault","year":"2015","unstructured":"C\u00f4t\u00e9-Daigneault J, Bouin M, Lahaie R et al (2015) Biologics in inflammatory bowel disease: what are the data? United European Gastroenterol J 3:419\u2013428","journal-title":"United European Gastroenterol J"},{"key":"1415_CR25","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/0148607113504002","volume":"38","author":"ZA Zator","year":"2014","unstructured":"Zator ZA, Cantu SM, Konijeti GG et al (2014) Pretreatment 25-hydroxyvitamin D levels and durability of anti-tumor necrosis factor-\u03b1 therapy in inflammatory bowel diseases. JPEN J Parenter Enter Nutr 38:385\u2013391","journal-title":"JPEN J Parenter Enter Nutr"},{"key":"1415_CR26","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1365-2036.2010.04355.x","volume":"32","author":"SP J\u00f8rgensen","year":"2010","unstructured":"J\u00f8rgensen SP, Agnholt J, Glerup H et al (2010) Clinical trial: vitamin D3 treatment in Crohn\u2019s disease\u2014a randomized double-blind placebo-controlled study. Aliment Pharmacol Ther 32:377\u2013383","journal-title":"Aliment Pharmacol Ther"},{"key":"1415_CR27","doi-asserted-by":"crossref","first-page":"7142","DOI":"10.3748\/wjg.v21.i23.7142","volume":"21","author":"GD Barboza de","year":"2015","unstructured":"de Barboza GD, Guizzardi S, de Talamoni NT (2015) Molecular aspects of intestinal calcium absorption. World J Gastroenterol 21:7142\u20137154","journal-title":"World J Gastroenterol"}],"updated-by":[{"DOI":"10.1007\/s11739-016-1464-0","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,5,19]],"date-time":"2016-05-19T00:00:00Z","timestamp":1463616000000}}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-016-1415-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11739-016-1415-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-016-1415-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T02:08:22Z","timestamp":1567649302000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11739-016-1415-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,3]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["1415"],"URL":"https:\/\/doi.org\/10.1007\/s11739-016-1415-9","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"value":"1828-0447","type":"print"},{"value":"1970-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,3]]}}}