{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:53:51Z","timestamp":1787169231846,"version":"build-2736575974"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T00:00:00Z","timestamp":1514937600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"DOI":"10.1007\/s11739-017-1778-6","type":"journal-article","created":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T11:07:54Z","timestamp":1514977674000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Sarcoidosis: a review for the internist"],"prefix":"10.1007","author":[{"given":"Elena","family":"Bargagli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Prasse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,1,3]]},"reference":[{"key":"1778_CR1","first-page":"149","volume":"16","author":"GW Hunninghake","year":"1999","unstructured":"Hunninghake GW, Costabel U, Ando M et al (1999) ATS\/ERS\/WASOG statement on sarcoidosis. American Thoracic Society\/European Respiratory Society\/World Association of Sarcoidosis and other granulomatous disorders. Sarcoidosis Vasc Diffuse Lung Dis 16:149\u2013173","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"1778_CR2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1165\/rcmb.2002-0164PS","volume":"27","author":"DR Moller","year":"2002","unstructured":"Moller DR, Chen ES (2002) Genetic basis of remitting sarcoidosis: triumph of the trimolecular complex? Am J Respir Cell Mol Biol 27:391\u2013395","journal-title":"Am J Respir Cell Mol Biol"},{"key":"1778_CR3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1183\/09031936.96.09010047","volume":"9","author":"C Prior","year":"1996","unstructured":"Prior C, Knight RA, Herold M (1996) Pulmonary sarcoidosis: patterns of cytokine release in vitro. Eur Respir J 9:47\u201353","journal-title":"Eur Respir J"},{"key":"1778_CR4","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.ccm.2015.08.012","volume":"36","author":"V Kouranos","year":"2015","unstructured":"Kouranos V, Jacob J, Wells AU (2015) Severe sarcoidosis. Clin Chest Med 36:715\u2013726","journal-title":"Clin Chest Med"},{"issue":"2","key":"1778_CR5","doi-asserted-by":"publisher","first-page":"1602419","DOI":"10.1183\/13993003.02419-2016","volume":"50","author":"B Duchemann","year":"2017","unstructured":"Duchemann B, Annesi-Maesano I, Jacobe de Naurois C, Sanyal S, Brillet PY, Brauner M, Kambouchner M, Huynh S, Naccache JM, Borie R, Piquet J, Mekinian A, Virally J, Uzunhan Y, Cadranel J, Crestani B, Fain O, Lhote F, Dhote R, Saidenberg-Kermanac\u2019h N, Rosental PA, Valeyre D, Nunes H (2017) Prevalence and incidence of interstitial lung diseases in a multi-ethnic county of Greater Paris. Eur Respir J 50(2):1602419. https:\/\/doi.org\/10.1183\/13993003.02419-2016","journal-title":"Eur Respir J"},{"key":"1778_CR6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1164\/rccm.200905-0696OC","volume":"181","author":"ES Chen","year":"2010","unstructured":"Chen ES, Song Z, Willett MH, Heine S, Yung RC, Liu MC, Groshong SD, Zhang Y, Tuder RM, Moller DR (2010) Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2. Am J Respir Crit Care Med 181:360\u2013373","journal-title":"Am J Respir Crit Care Med"},{"key":"1778_CR7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1378\/chest.84.5.522","volume":"84","author":"J Lieberman","year":"1983","unstructured":"Lieberman J, Schleissner LA, Nosal A, Sastre A, Mishkin FS (1983) Clinical correlations of serum angiotensin-converting enzyme (ACE) in sarcoidosis. A longitudinal study of serum ACE, 67gallium scans, chest roentgenograms, and pulmonary function. Chest 84:522\u2013528","journal-title":"Chest"},{"key":"1778_CR8","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.ccm.2008.03.004","volume":"29","author":"E Bargagli","year":"2008","unstructured":"Bargagli E, Mazzi A, Rottoli P (2008) Markers of inflammation in sarcoidosis: blood, urine, BAL, sputum, and exhaled gas. Clin Chest Med 29:445\u2013458","journal-title":"Clin Chest Med"},{"key":"1778_CR9","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jprot.2015.08.012","volume":"128","author":"C Landi","year":"2015","unstructured":"Landi C, Bargagli E, Carleo A et al (2015) A functional proteomics approach to the comprehension of sarcoidosis. J Proteom 128:375\u2013387","journal-title":"J Proteom"},{"key":"1778_CR10","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.rmed.2010.12.010","volume":"105","author":"E Bargagli","year":"2011","unstructured":"Bargagli E, Magi B, Olivieri C et al (2011) Analysis of serum amyloid A in sarcoidosis patients. Respir Med 105:775\u2013778","journal-title":"Respir Med"},{"key":"1778_CR11","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/eci.12610","volume":"46","author":"J Ivani\u0161evi\u0107","year":"2016","unstructured":"Ivani\u0161evi\u0107 J, Kotur-Stevuljevi\u0107 J, Stefanovi\u0107 A et al (2016) Association of serum amyloid A and oxidative stress with paraoxonase 1 in sarcoidosis patients. Eur J Clin Investig 46:418\u2013424","journal-title":"Eur J Clin Investig"},{"issue":"3","key":"1778_CR12","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1164\/rccm.200705-742OC","volume":"177","author":"A Prasse","year":"2008","unstructured":"Prasse A, Katic C, Germann M, Buchwald A, Zissel G, M\u00fcller-Quernheim J (2008) Phenotyping sarcoidosis from a pulmonary perspective. Am J Respir Crit Care Med 177(3):330\u2013336","journal-title":"Am J Respir Crit Care Med"},{"key":"1778_CR13","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1136\/bmj.2.5261.1165","volume":"4","author":"JG Scadding","year":"1961","unstructured":"Scadding JG (1961) Prognosis of intrathoracic sarcoidosis in England. BMJ 4:1165\u20131172","journal-title":"BMJ"},{"issue":"5","key":"1778_CR14","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s11739-017-1683-z","volume":"12","author":"B Chaigne","year":"2017","unstructured":"Chaigne B, Guillevin L (2017) Vasculitis for the internist: focus on ANCA-associated vasculitis. Intern Emerg Med 12(5):577\u2013585","journal-title":"Intern Emerg Med"},{"key":"1778_CR15","doi-asserted-by":"crossref","unstructured":"Elia F, Apr\u00e0 F, Crupi V (2017) Understanding and improving decisions in clinical medicine (II): making sense of reasoning in practice. Intern Emerg Med (in press)","DOI":"10.1007\/s11739-017-1740-7"},{"key":"1778_CR16","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1164\/rccm.200807-1082OC","volume":"179","author":"J Grunewald","year":"2009","unstructured":"Grunewald J, Eklund A (2009) Lofgren\u2019s syndrome: human leukocyte antigen strongly influences the disease course. Am J Respir Crit Care Med 179:307\u2013312","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"1778_CR17","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ccm.2015.08.003","volume":"36","author":"P Govender","year":"2015","unstructured":"Govender P, Berman JS (2015) The diagnosis of sarcoidosis. Clin Chest Med 36(4):585\u2013602","journal-title":"Clin Chest Med"},{"issue":"1","key":"1778_CR18","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.annder.2016.01.001","volume":"143","author":"V Descamps","year":"2016","unstructured":"Descamps V, Bouscarat F (2016) Cutaneous manifestations of sarcoidosis. Ann Dermatol Venereol 143(1):39\u201350","journal-title":"Ann Dermatol Venereol"},{"issue":"3","key":"1778_CR19","first-page":"209","volume":"33","author":"P Kingah","year":"2016","unstructured":"Kingah P, Alam M, Chugh K, Kamholz J, Samavati L (2016) Role of pulmonary evaluation in diagnosis of neurosarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 33(3):209\u2013215","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"issue":"4","key":"1778_CR20","first-page":"331","volume":"33","author":"MJ McDonnell","year":"2016","unstructured":"McDonnell MJ, Saleem MI, Wall D, Gilmartin JJ, Rutherford RM, O\u2019Regan A (2016) Predictive value of C-reactive protein and clinically relevant baseline variables in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 33(4):331\u2013340","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"1778_CR21","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ccm.2008.03.009","volume":"29","author":"MA Judson","year":"2008","unstructured":"Judson MA (2008) The diagnosis of sarcoidosis. Clin Chest Med 29:415\u2013427","journal-title":"Clin Chest Med"},{"issue":"5","key":"1778_CR22","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1097\/MCP.0000000000000400","volume":"23","author":"RP Baughman","year":"2017","unstructured":"Baughman RP, Papanikolaou I (2017) Current concepts regarding calcium metabolism and bone health in sarcoidosis. Curr Opin Pulm Med 23(5):476\u2013481","journal-title":"Curr Opin Pulm Med"},{"issue":"7","key":"1778_CR23","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s11739-017-1719-4","volume":"12","author":"S Minisola","year":"2017","unstructured":"Minisola S, Cipriani C, Occhiuto M, Pepe J (2017) New anabolic therapies for osteoporosis. Intern Emerg Med 12(7):915\u2013921","journal-title":"Intern Emerg Med"},{"issue":"6","key":"1778_CR24","first-page":"587","volume":"28","author":"H Kefella","year":"2017","unstructured":"Kefella H, Luther D, Hainline C (2017) Ophthalmic and neuro-ophthalmic manifestations of sarcoidosis. Curr Opin Pulm Med 28(6):587\u2013594","journal-title":"Curr Opin Pulm Med"},{"issue":"5","key":"1778_CR25","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/MCP.0000000000000409","volume":"23","author":"SJ Yang","year":"2017","unstructured":"Yang SJ, Salek S, Rosenbaum JT (2017) Ocular sarcoidosis: new diagnostic modalities and treatment. Curr Opin Pulm Med 23(5):458\u2013467","journal-title":"Curr Opin Pulm Med"},{"issue":"11","key":"1778_CR26","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.revmed.2016.05.008","volume":"37","author":"C Velter","year":"2016","unstructured":"Velter C, Lipsker D (2016) Cutaneous panniculitis. Rev Med Intern 37(11):743\u2013750","journal-title":"Rev Med Intern"},{"issue":"1","key":"1778_CR27","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000468536","volume":"233","author":"N Kluger","year":"2017","unstructured":"Kluger N (2017) Cutaneous complications related to tattoos: 31 cases from Finland. Dermatology 233(1):100\u2013109","journal-title":"Dermatology"},{"issue":"1","key":"1778_CR28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/BOR.0000000000000345","volume":"29","author":"I Tugal-Tutkun","year":"2017","unstructured":"Tugal-Tutkun I (2017) Systemic vasculitis and the eye. Curr Opin Rheumatol 29(1):24\u201332","journal-title":"Curr Opin Rheumatol"},{"issue":"5","key":"1778_CR29","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ophtha.2015.01.003","volume":"122","author":"AD Birnbaum","year":"2015","unstructured":"Birnbaum AD, French DD, Mirsaeidi M, Wehrli S (2015) Sarcoidosis in the national veteran population: association of ocular inflammation and mortality. Ophthalmology 122(5):934\u2013938","journal-title":"Ophthalmology"},{"issue":"11","key":"1778_CR30","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1007\/s00296-009-1315-7","volume":"31","author":"E Bargagli","year":"2011","unstructured":"Bargagli E, Olivieri C, Penza F, Bertelli P, Gonnelli S, Volterrani L, Rottoli P (2011) Rare localizations of bone sarcoidosis: two case reports and review of the literature. Rheumatol Int 31(11):1503\u20131506","journal-title":"Rheumatol Int"},{"issue":"3","key":"1778_CR31","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.path.2017.04.012","volume":"10","author":"JM Carter","year":"2017","unstructured":"Carter JM, Howe BM, Inwards CY (2017) Conditions simulating primary bone neoplasms. Surg Pathol Clin 10(3):731\u2013748","journal-title":"Surg Pathol Clin"},{"issue":"2","key":"1778_CR32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.rmed.2005.04.018","volume":"100","author":"P Rottoli","year":"2006","unstructured":"Rottoli P, Bargagli E, Chidichimo C, Nuti D, Cintorino M, Ginanneschi C, Caruso G (2006) Sarcoidosis with upper respiratory tract involvement. Respir Med 100(2):253\u2013257","journal-title":"Respir Med"},{"issue":"6","key":"1778_CR33","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1586\/ers.11.66","volume":"5","author":"AS Morgenthau","year":"2011","unstructured":"Morgenthau AS, Teirstein AS (2011) Sarcoidosis of the upper and lower airways. Expert Rev Respir Med 5(6):823\u2013833","journal-title":"Expert Rev Respir Med"},{"issue":"12","key":"1778_CR34","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/j.rmed.2015.10.002","volume":"109","author":"A Agrawal","year":"2015","unstructured":"Agrawal A, Sahni S, Iftikhar A, Talwar A (2015) Pulmonary manifestations of renal cell carcinoma. Respir Med 109(12):1505\u20131508","journal-title":"Respir Med"},{"key":"1778_CR35","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1378\/chest.07-2784","volume":"133","author":"D Mehta","year":"2008","unstructured":"Mehta D, Lubitz SA, Frankel Z, Wisnivesky JP, Einstein AJ, Goldman M, Machac J, Teirstein A (2008) Cardiac involvement in patients with sarcoidosis: diagnostic and prognostic value of outpatient testing. Chest 133:1426\u20131435","journal-title":"Chest"},{"key":"1778_CR36","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1378\/chest.128.1.30","volume":"128","author":"JP Smedema","year":"2005","unstructured":"Smedema JP, Snoep G, van Kroonenburgh MP, van Geuns RJ, Dassen WR, Gorgels AP, Crijns HJ (2005) Cardiac involvement in patients with pulmonary sarcoidosis assessed at two university medical centers in the Netherlands. Chest 128:30\u201335","journal-title":"Chest"},{"issue":"4","key":"1778_CR37","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1055\/s-0037-1604165","volume":"38","author":"DA Culver","year":"2017","unstructured":"Culver DA, Ribeiro Neto ML, Moss BP, Willis MA (2017) Neurosarcoidosis. Semin Respir Crit Care Med 38(4):499\u2013513","journal-title":"Semin Respir Crit Care Med"},{"issue":"18","key":"1778_CR38","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.2169\/internalmedicine.8217-16","volume":"56","author":"Y Ogawa","year":"2017","unstructured":"Ogawa Y, Saraya T, Fujiwara M, Takizawa H (2017) Massive neurosarcoidosis. Intern Med 56(18):2537\u20132538","journal-title":"Intern Med"},{"issue":"2","key":"1778_CR39","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s00415-014-7482-9","volume":"262","author":"R Hebel","year":"2015","unstructured":"Hebel R, Dubaniewicz-Wybieralska M, Dubaniewicz A (2015) Overview of neurosarcoidosis: recent advances. J Neurol 262(2):258\u2013267","journal-title":"J Neurol"},{"issue":"115","key":"1778_CR40","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/B978-0-444-52902-2.00027-8","volume":"013","author":"G Said","year":"2013","unstructured":"Said G (2013) Sarcoidosis of the peripheral nervous system. Handb Clin Neurol 013(115):485\u2013495","journal-title":"Handb Clin Neurol"},{"key":"1778_CR41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2147\/CEG.S136803","volume":"10","author":"DG Levitt","year":"2017","unstructured":"Levitt DG, Levitt MD (2017) Protein losing enteropathy: comprehensive review of the mechanistic association with clinical and subclinical disease states. Clin Exp Gastroenterol 10:147\u2013168","journal-title":"Clin Exp Gastroenterol"},{"issue":"5","key":"1778_CR42","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.hrtlng.2017.05.009","volume":"46","author":"BA Cunha","year":"2017","unstructured":"Cunha BA, Sivarajah T, Jimada I (2017) Sarcoidosis with fever and a splenic infarct due to CMV or lymphoma? Heart Lung 46(5):394\u2013396","journal-title":"Heart Lung"},{"issue":"6","key":"1778_CR43","doi-asserted-by":"crossref","first-page":"e0178936","DOI":"10.1371\/journal.pone.0178936","volume":"12","author":"L Baratto","year":"2017","unstructured":"Baratto L, Park SY, Hatami N, Davidzon G, Srinivas S, Gambhir SS, Iagaru A (2017) 18F-FDG silicon photomultiplier PET\/CT: a pilot study comparing semi-quantitative measurements with standard PET\/CT. PLoS One 12(6):e0178936","journal-title":"PLoS One"},{"issue":"1","key":"1778_CR44","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s12016-015-8478-7","volume":"49","author":"M Silva","year":"2015","unstructured":"Silva M, Nunes H, Valeyre D, Sverzellati N (2015) Imaging of sarcoidosis. Clin Rev Allergy Immunol 49(1):45\u201353","journal-title":"Clin Rev Allergy Immunol"},{"key":"1778_CR45","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.2147\/TCRM.S74476","volume":"12","author":"K Al-Kofahi","year":"2016","unstructured":"Al-Kofahi K, Korsten P, Ascoli C, Virupannavar S, Mirsaeidi M, Chang I, Qaqish N, Saketkoo LA, Baughman RP, Sweiss NJ (2016) Management of extrapulmonary sarcoidosis: challenges and solutions. Ther Clin Risk Manag 12:1623\u20131634","journal-title":"Ther Clin Risk Manag"},{"issue":"8","key":"1778_CR46","doi-asserted-by":"crossref","first-page":"e0154716","DOI":"10.1371\/journal.pone.0154716","volume":"11","author":"C Fang","year":"2016","unstructured":"Fang C, Huang H, Xu Z (2016) Immunological evidence for the role of mycobacteria in sarcoidosis: a meta-analysis. PLoS One 11(8):e0154716","journal-title":"PLoS One"},{"issue":"5","key":"1778_CR47","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1159\/000479745","volume":"94","author":"CC Tyan","year":"2017","unstructured":"Tyan CC, Machuca T, Czarnecka K, Ko HM, da Cunha Santos G, Boerner SL, Pierre A, Cypel M, Waddell T, Darling G, de Perrot M, Keshavjee S, Geddie W, Yasufuku K (2017) Performance of endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of isolated mediastinal and hilar lymphadenopathy. Respiration 94(5):457\u2013464","journal-title":"Respiration"},{"issue":"1","key":"1778_CR48","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/00325481.2017.1251818","volume":"129","author":"V Ramachandraiah","year":"2017","unstructured":"Ramachandraiah V, Aronow W, Chandy D (2017) Pulmonary sarcoidosis: an update. Postgrad Med 129(1):149\u2013158","journal-title":"Postgrad Med"},{"issue":"4","key":"1778_CR49","first-page":"285","volume":"60","author":"L Presotto","year":"2016","unstructured":"Presotto L, Busnardo E, Gianolli L, Bettinardi V (2016) An update on technical and methodological aspects for cardiac PET applications. Q J Nucl Med Mol Imaging 60(4):285\u2013307","journal-title":"Q J Nucl Med Mol Imaging"},{"issue":"4","key":"1778_CR50","first-page":"334","volume":"15","author":"E Mortaz","year":"2016","unstructured":"Mortaz E, Rezayat F, Amani D, Kiani A, Garssen J, Adcock IM, Velayati A (2016) The roles of T helper 1, T helper 17 and regulatory T cells in the pathogenesis of sarcoidosis. Iran J Allergy Asthma Immunol 15(4):334\u2013339","journal-title":"Iran J Allergy Asthma Immunol"},{"issue":"1","key":"1778_CR51","first-page":"12","volume":"14","author":"E Mortaz","year":"2015","unstructured":"Mortaz E, Gudarzi H, Tabarsi P, Adcock IM, Masjedi MR, Jamaati HR, Garssen J, Velayati AA, Redegeld FA (2015) Flow cytometry applications in the study of immunological lung disorders. Iran J Allergy Asthma Immunol 14(1):12\u201318","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"1778_CR52","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s10875-012-9754-4","volume":"33","author":"E Bargagli","year":"2013","unstructured":"Bargagli E, Bennett D, Maggiorelli C et al (2013) Human chitotriosidase: a sensitive biomarker of sarcoidosis. J Clin Immunol 33:264\u2013270","journal-title":"J Clin Immunol"}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-017-1778-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11739-017-1778-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-017-1778-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T11:08:30Z","timestamp":1514977710000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11739-017-1778-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,3]]},"references-count":52,"alternative-id":["1778"],"URL":"https:\/\/doi.org\/10.1007\/s11739-017-1778-6","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"value":"1828-0447","type":"print"},{"value":"1970-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,3]]}}}