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The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC).  The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria.<\/jats:p>","DOI":"10.1007\/s11739-020-02601-y","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T06:02:16Z","timestamp":1608789736000},"page":"309-312","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["COVID-19 coagulopathy: is it disseminated intravascular coagulation?"],"prefix":"10.1007","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2212-5299","authenticated-orcid":false,"given":"Marcel","family":"Levi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Iba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,12,24]]},"reference":[{"key":"2601_CR1","doi-asserted-by":"publisher","first-page":"2000607","DOI":"10.1183\/13993003.00607-2020","volume":"55","author":"RJ Mason","year":"2020","unstructured":"Mason RJ (2020) Pathogenesis of COVID-19 from a cell biology perspective. 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