{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:22:21Z","timestamp":1740147741305,"version":"3.37.3"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1007\/s11739-024-03657-w","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T17:01:37Z","timestamp":1717174897000},"page":"1637-1644","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Risk of early clinical deterioration and 30-day mortality in pulmonary embolism intermediate\u2013high-risk patients with patent foramen ovale"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4559-1292","authenticated-orcid":false,"given":"Marco","family":"Zuin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Rigatelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Bilato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amedeo","family":"Bongarzoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Zonzin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Casazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loris","family":"Roncon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,31]]},"reference":[{"key":"3657_CR1","doi-asserted-by":"publisher","first-page":"15086","DOI":"10.1038\/nrdp.2015.86","volume":"2","author":"S Homma","year":"2016","unstructured":"Homma S, Mess\u00e9 SR, Rundek T, Sun YP, Franke J, Davidson K, Sievert H, Sacco RL, Di Tullio MR (2016) Patent foramen ovale. Nat Rev Dis Primers 2:15086","journal-title":"Nat Rev Dis Primers"},{"key":"3657_CR2","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1093\/eurheartj\/ehaa1070","volume":"42","author":"C Pristipino","year":"2021","unstructured":"Pristipino C, Germonpr\u00e9 P, Toni D, Sievert H, Meier B, D\u2019Ascenzo F, Berti S, Onorato EM, Bedogni F, Mas JL, Scacciatella P, Hildick-Smith D, Gaita F, Kyrle PA, Thomson J, Derumeaux G, Sibbing D, Chessa M, Hornung M, Zamorano J, Dudek D (2021) European position paper on the management of patients with patent foramen ovale. Part II - Decompression sickness, migraine, arterial deoxygenation syndromes and select high-risk clinical conditions. Eur Heart J 42:1545\u20131553","journal-title":"Eur Heart J"},{"key":"3657_CR3","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1161\/01.CIR.97.19.1946","volume":"97","author":"S Konstantinides","year":"1998","unstructured":"Konstantinides S, Geibel A, Kasper W, Olschewski M, Bl\u00fcmel L, Just H (1998) Patent foramen ovale is an important predictor of adverse outcome in patients with major pulmonary embolism. Circulation 97:1946\u20131951","journal-title":"Circulation"},{"key":"3657_CR4","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.thromres.2021.03.005","volume":"202","author":"K Lacut","year":"2021","unstructured":"Lacut K, Le Moigne E, Couturaud F, Font C, V\u00e1zquez FJ, Ca\u00f1as I, D\u00edaz-Peromingo JA, Gil-D\u00edaz A, Bucherini E, Monreal M, RIETE investigators, (2021) Outcomes in patients with acute pulmonary embolism and patent foramen ovale: Findings from the RIETE registry. Thromb Res 202:59\u201366","journal-title":"Thromb Res"},{"key":"3657_CR5","doi-asserted-by":"publisher","first-page":"756","DOI":"10.7326\/M18-3485","volume":"170","author":"E Le Moigne","year":"2019","unstructured":"Le Moigne E, Timsit S, Ben Salem D, Didier R, Jobic Y, Paleiron N, Le Mao R, Joseph T, Hoffmann C, Dion A, Rousset J, Le Gal G, Lacut K, Leroyer C, Mottier D, Couturaud F (2019) Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism: A Prospective Cohort Study. Ann Intern Med 170:756\u2013763","journal-title":"Ann Intern Med"},{"key":"3657_CR6","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1093\/eurheartj\/ehz405","volume":"41","author":"Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jim\u00e9nez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, N\u00ed \u00c1inle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL; ESC Scientific Document Group","year":"2020","unstructured":"Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jim\u00e9nez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, N\u00ed \u00c1inle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL; ESC Scientific Document Group (2020) 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 41:543\u2013603","journal-title":"Eur Heart J"},{"key":"3657_CR7","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1016\/j.jacc.2020.05.028","volume":"76","author":"G Piazza","year":"2020","unstructured":"Piazza G (2020) Advanced Management of Intermediate- and High-Risk Pulmonary Embolism: JACC Focus Seminar. J Am Coll Cardiol 76:2117\u20132127","journal-title":"J Am Coll Cardiol"},{"key":"3657_CR8","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/j.thromres.2012.08.292","volume":"130","author":"F Casazza","year":"2012","unstructured":"Casazza F, Becattini C, Bongarzoni A, Cuccia C, Roncon L, Favretto G, Zonzin P, Pignataro L, Agnelli G (2012) Clinical features and short term outcomes of patients with acute pulmonary embolism. The Italian Pulmonary Embolism Registry (IPER). Thromb Res 130:847\u2013852","journal-title":"Thromb Res"},{"key":"3657_CR9","first-page":"2276","volume":"9","author":"A Torbicki","year":"2008","unstructured":"Torbicki A, Perrier A, Konstantinides S, Agnelli G, Gali\u00e8 N, Pruszczyk P et al (2008) Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 9:2276\u20132315","journal-title":"Eur Heart J"},{"key":"3657_CR10","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.ijcard.2019.11.102","volume":"302","author":"A Quezada","year":"2020","unstructured":"Quezada A, Jim\u00e9nez D, Bikdeli B, Moores L, Porres-Aguilar M, Aramberri M, Lima J, Ballaz A, Yusen RD, Monreal M, RIETE investigators, (2020) Systolic blood pressure and mortality in acute symptomatic pulmonary embolism. Int J Cardiol 302:157\u2013163","journal-title":"Int J Cardiol"},{"key":"3657_CR11","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.thromres.2022.07.003","volume":"217","author":"M Zuin","year":"2022","unstructured":"Zuin M, Rigatelli G, Bilato C, Bongarzoni A, Casazza F, Zonzin P, Roncon L (2022) Prognostic role of serial electrocardiographic changes in patients with acute pulmonary embolism. Data from the Italian Pulmonary Embolism Registry. Thromb Res 217:15\u201321","journal-title":"Thromb Res"},{"key":"3657_CR12","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.jcmg.2010.01.007","volume":"3","author":"BS Rana","year":"2010","unstructured":"Rana BS, Thomas MR, Calvert PA, Monaghan MJ, Hildick-Smith D (2010) Echocardiographic evaluation of patent foramen ovale prior to device closure. JACC Cardiovasc Imaging 3:749\u2013760","journal-title":"JACC Cardiovasc Imaging"},{"key":"3657_CR13","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1007\/s10554-019-01666-x","volume":"35","author":"G Rigatelli","year":"2019","unstructured":"Rigatelli G, Zuin M, Adami A, Aggio S, Lanza D, d\u2019Elia K, Braggion G, Russo M, Mazza A, Roncon L (2019) Left atrial enlargement as a maker of significant high-risk patent foramen ovale. Int J Cardiovasc Imaging 35:2049\u20132056","journal-title":"Int J Cardiovasc Imaging"},{"key":"3657_CR14","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1378\/chest.12-2938","volume":"144","author":"C Becattini","year":"2013","unstructured":"Becattini C, Casazza F, Forgione C, Porro F, Fadin BM, Stucchi A, Lignani A, Conte L, Imperadore F, Bongarzoni A, Agnelli G (2013) Acute pulmonary embolism: external validation of an integrated risk stratification model. Chest 144:1539\u20131545","journal-title":"Chest"},{"key":"3657_CR15","first-page":"1224","volume":"134","author":"C Becattini","year":"2014","unstructured":"Becattini C, Casazza F, Forgione C, Porro F, Fadin BM, Stucchi A, Lignani A, Conte L, Imperadore F, Bongarzoni A, Agnelli G (2014) Echocardiographic evolution of pulmonary artery pressure after acute pulmonary embolism. Results from IPER registry Thromb Res 134:1224\u20131228","journal-title":"Results from IPER registry Thromb Res"},{"key":"3657_CR16","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1378\/chest.14-0100","volume":"146","author":"D Doyen","year":"2014","unstructured":"Doyen D, Castellani M, Moceri P, Chiche O, Lazdunski R, Bertora D, Cerboni P, Chaussade C, Ferrari E (2014) Patent foramen ovale and stroke in intermediate-risk pulmonary embolism. Chest 146:967\u2013973","journal-title":"Chest"},{"key":"3657_CR17","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/S0025-6196(12)60336-X","volume":"59","author":"PT Hagen","year":"1984","unstructured":"Hagen PT, Scholz DG, Edwards WD (1984) Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clin Proc 59:17\u201320","journal-title":"Mayo Clin Proc"},{"key":"3657_CR18","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1161\/CIRCULATIONAHA.104.524371","volume":"112","author":"S Homma","year":"2005","unstructured":"Homma S, Sacco RL (2005) Patent foramen ovale and stroke. Circulation 112:1063\u20131072","journal-title":"Circulation"},{"key":"3657_CR19","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/S0828-282X(08)70591-9","volume":"24","author":"N Gomperts","year":"2008","unstructured":"Gomperts N, Fowler R, Horlick E, McLaughlin P (2008) A broken heart: right-to-left shunt in the setting of normal cardiac pressures. Can J Cardiol 24:227\u2013229","journal-title":"Can J Cardiol"},{"key":"3657_CR20","doi-asserted-by":"publisher","first-page":"336","DOI":"10.3389\/fneur.2020.00336","volume":"11","author":"A Zietz","year":"2020","unstructured":"Zietz A, Sutter R, De Marchis GM (2020) Deep Vein Thrombosis and Pulmonary Embolism Among Patients With a Cryptogenic Stroke Linked to Patent Foramen Ovale-A Review of the Literature. Front Neurol 11:336","journal-title":"Front Neurol"},{"key":"3657_CR21","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.amjcard.2023.07.095","volume":"208","author":"R Feroze","year":"2023","unstructured":"Feroze R, Khawaja T, Arora S, Tashtish N, Castro-Dominguez Y, Hammad T, Osman MN, Gupta A, Schilz R, Shishehbor MH, Li J (2023) Prognostic Value of Pulmonary Artery Oxygen Saturation in Pulmonary Embolism Requiring Endovascular Intervention. Am J Cardiol 208:13\u201315","journal-title":"Am J Cardiol"},{"key":"3657_CR22","doi-asserted-by":"publisher","first-page":"35","DOI":"10.4103\/0974-2069.64372","volume":"3","author":"Z Amin","year":"2010","unstructured":"Amin Z (2010) Patent foramen ovale closure. Ann Pediatr Cardiol 3:35\u201339","journal-title":"Ann Pediatr Cardiol"},{"key":"3657_CR23","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1186\/s12890-019-1005-5","volume":"19","author":"Y Wang","year":"2019","unstructured":"Wang Y, Yang H, Qiao L, Tan Z, Jin J, Yang J, Zhang L, Fang BM, Xu X (2019) The predictive value of PaO2\/FIO2 and additional parameters for in-hospital mortality in patients with acute pulmonary embolism: an 8-year prospective observational single-center cohort study. BMC Pulm Med 19:242","journal-title":"BMC Pulm Med"},{"key":"3657_CR24","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1177\/0218492317746252","volume":"26","author":"M Subramanian","year":"2018","unstructured":"Subramanian M, Ramadurai S, Arthur P, Gopalan S (2018) Hypoxia as an independent predictor of adverse outcomes in pulmonary embolism. Asian Cardiovasc Thorac Ann 26:38\u201343","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"3657_CR25","doi-asserted-by":"publisher","first-page":"2726","DOI":"10.1161\/01.CIR.0000097829.89204.0C","volume":"108","author":"SZ Goldhaber","year":"2003","unstructured":"Goldhaber SZ, Elliott CG (2003) Acute pulmonary embolism: part I: epidemiology, pathophysiology, and diagnosis. Circulation 108:2726\u20132729","journal-title":"Circulation"},{"key":"3657_CR26","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.4187\/respcare.06797","volume":"64","author":"L Domaradzki","year":"2019","unstructured":"Domaradzki L, Ghahramani M, Rogers R, Ruzieh M, Wilson R, Van de Louw A (2019) SpO2 \/FIO2 on presentation as a predictor for early hemodynamic deterioration in intermediate risk acute pulmonary embolism. Respir Care 64:1279\u20131285","journal-title":"Respir Care"},{"key":"3657_CR27","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.jcct.2017.11.009","volume":"12","author":"M Zhang","year":"2018","unstructured":"Zhang M, Tan S, Patel V, Zalta BA, Shmukler A, Levsky JM, Jain VR, Shaban NM, Haramati LB (2018) Patent foramen ovale in patients with pulmonary embolism: A prognostic factor on CT pulmonary angiography? J Cardiovasc Comput Tomogr 12:271\u2013274","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"3657_CR28","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.thromres.2021.04.022","volume":"203","author":"G Rigatelli","year":"2021","unstructured":"Rigatelli G, Zuin M (2021) Not all patent foramen ovales are alike! Thromb Res 203:81","journal-title":"Thromb Res"},{"key":"3657_CR29","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1017\/S1047951109990631","volume":"20","author":"G Rigatelli","year":"2010","unstructured":"Rigatelli G, Dell\u2019Avvocata F, Ronco F, Giordan M, Cardaioli P (2010) Patent oval foramen transcatheter closure: results of a strategy based on tailoring the device to the specific patient\u2019s anatomy. Cardiol Young 20:144\u2013149","journal-title":"Cardiol Young"}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-024-03657-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11739-024-03657-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-024-03657-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T12:17:45Z","timestamp":1726489065000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11739-024-03657-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,31]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["3657"],"URL":"https:\/\/doi.org\/10.1007\/s11739-024-03657-w","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"type":"print","value":"1828-0447"},{"type":"electronic","value":"1970-9366"}],"subject":[],"published":{"date-parts":[[2024,5,31]]},"assertion":[{"value":"7 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None of the authors has conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The protocol of the study was approved by the institutional review boards both at the coordinating center (San Carlo Borromeo Hospital Ethical Committee; approval number 364; April 12, 2006) and in every recruiting hospital.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All participants provided informed consent prior to their participation.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}