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This study examines self-rated health (SRH) outcomes among exclusive e-cigarette users versus exclusive traditional cigarette smokers, using data from the Health Survey for England 2019. From an initial sample of 10,299 participants, the study focused on 8204 adults, excluding those aged 0\u201315. Further refinement to exclusive nicotine product users led to 274 e-cigarette users and 1017 cigarette smokers, after excluding dual users, never users, ex-users, non-responders, and users of other tobacco products such as pipes and cigars. SRH was derived from participants\u2019 responses to a question asking how they rated their general health, with five possible options: \u201cvery good\u201d, \u201cgood\u201d, \u201cfair\u201d, \u201cbad\u201d, and \u201cvery bad\u201d. For the purposes of this study, these responses were collapsed into two categories: \u201cGood Health\u201d (combining \u201cvery good\u201d and \u201cgood\u201d) and \u201cPoor Health\u201d (combining \u201cfair\u201d, \u201cbad\u201d, and \u201cvery bad\u201d). Consequently, 834 participants were classified as reporting good health, while 457 reported poor health. Binary logistic regression, adjusted for factors such as age, sex, ethnicity, residence, education, body mass index, alcohol use, age started smoking, physical or mental health conditions, and frequency of GP visits, revealed that exclusive e-cigarette users were significantly more likely to report good health compared to exclusive cigarette smokers, with an odds ratio\u00a0(OR) of 1.59 (95% CI: 1.10 \u2013 2.32, <jats:italic>p<\/jats:italic>\u2009=\u20090.014). As a sensitivity analysis, a generalized ordered logistic regression model was performed using the original five SRH categories. The adjusted model confirmed consistent results, with exclusive e-cigarette users showing higher odds of reporting better health across the full range of SRH outcomes (OR\u2009=\u20091.40, 95% CI: 1.08\u20131.82, <jats:italic>p<\/jats:italic>\u2009=\u20090.011). These findings suggest that exclusive e-cigarette users perceive their health more positively than traditional cigarette smokers, contributing useful insights to the discussions around harm reduction strategies.<\/jats:p>","DOI":"10.1007\/s11739-024-03817-y","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T12:13:28Z","timestamp":1731672808000},"page":"441-452","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Comparing self-rated health among exclusive e-cigarette users and traditional cigarette smokers: an analysis of the Health Survey for England 2019"],"prefix":"10.1007","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2381-0984","authenticated-orcid":false,"given":"Yusuff Adebayo","family":"Adebisi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duaa Abdullah","family":"Bafail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"issue":"4","key":"3817_CR1","doi-asserted-by":"publisher","first-page":"e38073","DOI":"10.7759\/cureus.38073","volume":"15","author":"MP Parmar","year":"2023","unstructured":"Parmar MP, Kaur M, Bhavanam S et al (2023) A systematic review of the effects of smoking on the cardiovascular system and general health. 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KAC receives funding from Global Action to End Smoking (GA), an independent U.S. nonprofit 501(c)(3) grantmaking organization that supports Health & Science Research, Cessation Education, and Agricultural Transformation initiatives. The scholarship and fellowship did not influence the study\u2019s design, preparation, writing, or interpretation of findings. The contents, selection, and presentation of facts, as well as any opinions expressed, are the sole responsibility of the authors and do not reflect the positions of KAC or GA. The research presented in this paper was conducted independently of any external funding sources. Abdullah Bafail declares no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Approval for this analysis was granted by the UK Statistics Authority Data Ethics Team, falling under the National Statistician\u2019s Data Ethics Advisory Committee while East Midlands-Nottingham 2 Research Ethics Committee; 15\/EM\/0254 approved the research ethics. All survey respondents provided verbal informed consent to participate in the Health Survey for England.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Patients and\/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient and public involvement"}},{"value":"This study is based on the analysis of secondary data obtained from the Health Survey for England (HSE) 2019, which consists of anonymized, publicly accessible data. The data were collected by the original researchers in compliance with ethical standards, and informed consent was obtained from all participants by the original data collectors. As this study involved secondary data analysis, no additional ethical approval or informed consent was required by the authors for this research, as it qualifies for exemption from human subject research.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights and Informed consent"}}]}}