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Javier Loricera had consultation fees\/participation in company-sponsored speaker\u2019s bureau from Roche, Gal\u00e1pagos, Novartis, UCB Pharma, MSD, Celgene, Astra Zeneca, and Gr\u00fcnenthal. He received support for attending meetings and\/or travel from Janssen, Abbvie, Roche, Novartis, MSD, UCB Pharma, Celgene, Lilly, Pfizer, and Gal\u00e1pagos. Santos Casta\u00f1eda has received research support from MSD and Pfizer and had consultation fees\/participation in the company-sponsored speaker\u2019s bureau from BMS, Eli-Lilly, MSD, Roche, and UCB. S. Casta\u00f1eda is also assistant professor of the c\u00e1tedra EPID-Future, funded by UAM-Roche, Universidad Aut\u00f3noma de Madrid (UAM), Spain. Ricardo Blanco received grants\/research support from AbbVie, MSD, and Roche. He also received consultation fees\/participation in a company-sponsored speaker\u2019s bureau from AbbVie, Pfizer, Roche, Bristol-Myers, Janssen, Lilly, UCB, and MSD. The following authors did not declare financial disclosure: Carmen Secada-G\u00f3mez, Adri\u00e1n Mart\u00edn, Fernando L\u00f3pez Guti\u00e9rrez, Luc\u00eda Garc\u00eda-Alcalde, Mar\u00eda N\u00fa\u00f1ez-Sayar, Ander Ucelay-Aristi, Isabel Mart\u00ednez Rodr\u00edguez.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Local Clinical Research Ethics Committee (ethical approval code: 2023.013) and was carried out following the protocol and the standard procedures that ensure compliance with Declaration of Helsinki and Good Clinical Practice standards. Animals were not involved in this research. 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