{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T10:51:55Z","timestamp":1775645515826,"version":"3.50.1"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["113-2314-B-016 -051 -MY3"],"award-info":[{"award-number":["113-2314-B-016 -051 -MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intern Emerg Med"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1007\/s11739-025-04200-1","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T16:39:25Z","timestamp":1762879165000},"page":"599-603","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent severe hypercalcemia in a nasopharyngeal carcinoma survivor"],"prefix":"10.1007","volume":"21","author":[{"given":"Liang-Hsi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Juei","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8014-6311","authenticated-orcid":false,"given":"Shun-Neng","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"issue":"4","key":"4200_CR1","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1056\/NEJMcp042806","volume":"352","author":"AF Stewart","year":"2005","unstructured":"Stewart AF (2005) Clinical practice Hypercalcemia associated with cancer. The New England J Med 352(4):373\u2013379. https:\/\/doi.org\/10.1056\/NEJMcp042806","journal-title":"The New England J Med"},{"issue":"4","key":"4200_CR2","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1053\/j.ajkd.2008.11.015","volume":"53","author":"S Hanada","year":"2009","unstructured":"Hanada S, Iwamoto M, Kobayashi N, Ando R, Sasaki S (2009) Calcium-alkali syndrome due to vitamin D administration and magnesium oxide administration. Am J Kidney Dis 53(4):711\u2013714. https:\/\/doi.org\/10.1053\/j.ajkd.2008.11.015","journal-title":"Am J Kidney Dis"},{"issue":"Supplement_1","key":"4200_CR3","doi-asserted-by":"publisher","first-page":"A154","DOI":"10.1210\/jendso\/bvab048.312","volume":"5","author":"J Turner","year":"2021","unstructured":"Turner J, Haider A, Barghouthi N, Symczyk O (2021) Pth-independent hypercalcemia in undiagnosed adrenal insufficiency. J Endocr Soc 5(Supplement_1):A154\u2013A155. https:\/\/doi.org\/10.1210\/jendso\/bvab048.312","journal-title":"J Endocr Soc"},{"issue":"12","key":"4200_CR4","doi-asserted-by":"publisher","first-page":"4880","DOI":"10.3390\/nu5124880","volume":"5","author":"AM Patel","year":"2013","unstructured":"Patel AM, Adeseun GA, Goldfarb S (2013) Calcium-alkali syndrome in the modern era. Nutrients 5(12):4880\u20134893. https:\/\/doi.org\/10.3390\/nu5124880","journal-title":"Nutrients"},{"issue":"7","key":"4200_CR5","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1055\/s-0035-1549963","volume":"123","author":"SH Ipekci","year":"2015","unstructured":"Ipekci SH, Cakir M, Kiyici A, Koc O, Artac M (2015) Radiotherapy-induced hypopituitarism in nasopharyngeal carcinoma: the tip of an iceberg,. Exp Clin Endocrinol Diabetes 123(7):411\u2013418. https:\/\/doi.org\/10.1055\/s-0035-1549963","journal-title":"Exp Clin Endocrinol Diabetes"}],"container-title":["Internal and Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-025-04200-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11739-025-04200-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11739-025-04200-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T10:01:16Z","timestamp":1775642476000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11739-025-04200-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,11]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["4200"],"URL":"https:\/\/doi.org\/10.1007\/s11739-025-04200-1","relation":{},"ISSN":["1828-0447","1970-9366"],"issn-type":[{"value":"1828-0447","type":"print"},{"value":"1970-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,11]]},"assertion":[{"value":"8 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors, Liang-Hsi Chen, Yu-Juei Hsu, and Shun-Neng Hsu, declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was conducted in accordance with the ethical standards of the Institutional Review Board of Tri-Service General Hospital (IRB No.: A202515123).\u00a0Written informed consent was obtained from the patient for participation in this case report and for publication of the clinical details and accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and patient consent"}},{"value":"During the preparation of this work, the author utilized ChatGPT-4 to review grammar and spelling. After utilizing this tool\/service, the authors reviewed and edited the content as needed and assumed full responsibility for the publication's content.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declaration of generative AI technologies in the writing process"}}]}}