{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:52:01Z","timestamp":1791190321694,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this pulse\u2010chase study, rainbow trout fed a diet containing deuterated (D<jats:sub>5<\/jats:sub>) (17,17,18,18,18)\u201018\u22363n\u22123 ethyl ester accumulated D<jats:sub>5<\/jats:sub>\u201022\u22366n\u22123 in pyloric ceca to a greater extent than in liver 2 d post\u2010dose. The ratio of newly synthesized D<jats:sub>5<\/jats:sub>\u201022\u22366n\u22123 in ceca to that in liver 2 d after feeding D<jats:sub>5<\/jats:sub>\u201018\u22363n\u22123 was 4.7\u00b11.2 when expressed as per mg tissue and 5.2\u00b12.4 when expressed as per mg protein. The amount of D<jats:sub>5<\/jats:sub>\u201022\u22366n\u22123 in ceca then declined whereas that in liver and blood increased, with the ratio of ceca to liver falling to 1.7 and 1.4, respectively, by day 5 and approaching unity by day 9. A crude cecal mucosa fraction contained 123\u00b150 ng D<jats:sub>5<\/jats:sub>\u201022\u22366n\u22123\/mg protein\/mg D<jats:sub>5<\/jats:sub>\u201018\u22363n\u22123 eaten 2 d after feeding the tracer, compared with 35\u00b121 ng D<jats:sub>5<\/jats:sub>\u201022\u22366n\u22123\/mg protein\/mg D<jats:sub>5<\/jats:sub>\u201018\u22363n\u22123 eaten in liver. Three days later the amount in cecal mucosa had fallen by one\u2010third and that in liver had increased threefold. Most of the D<jats:sub>5<\/jats:sub>\u201018\u22363n\u22123 was catabolized very rapidly. The ratio of D<jats:sub>5<\/jats:sub>\u201018\u22363n\u22123 to 21\u22364n\u22126 (a relatively inert FA marker) in the diet was 4.0, but this fell to 0.30 in ceca and <jats:italic>ca.<\/jats:italic> 0.8 in liver, blood, and whole carcass one day after feeding. These results indicate that ceca are active in the synthesis of 22\u22366n\u22123 and the oxidation of 18\u22363n\u22123.<\/jats:p>","DOI":"10.1007\/s11745-003-1029-5","type":"journal-article","created":{"date-parts":[[2006,11,13]],"date-time":"2006-11-13T19:46:24Z","timestamp":1163447184000},"page":"39-44","source":"Crossref","is-referenced-by-count":54,"title":["Pyloric ceca are significant sites of newly synthesized 22\u22366n\u22123 in rainbow trout (<i>Oncorhynchus mykiss<\/i>)"],"prefix":"10.1002","volume":"38","author":[{"given":"M. V.","family":"Bell","sequence":"first","affiliation":[{"name":"Institute of Aquaculture University of Stirling Stirling FK9 4LA Scotland, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. R.","family":"Dick","sequence":"additional","affiliation":[{"name":"Institute of Aquaculture University of Stirling Stirling FK9 4LA Scotland, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. E. A.","family":"Porter","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences University of Stirling Stirling FK9 4LA Scotland, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,1]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7827(82)90015-7"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7827(87)90002-6"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00212a040"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)54882-1"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(95)00211-1"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-001-0807-4"},{"key":"e_1_2_2_8_1","first-page":"153","volume-title":"Fish Nutrition","author":"Sargent J.R.","year":"1989"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-001-0826-1"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-997-0078-0"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(95)02052-7"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)64849-5"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)41393-8"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/1439672"},{"key":"e_1_2_2_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(85)90057-2"},{"key":"e_1_2_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(81)90135-6"},{"key":"e_1_2_2_18_1","first-page":"G65","article-title":"Pyloric Ceca of Fish: A \u201cNew\u201d Absorptive Organ","volume":"252","author":"Buddington R.K.","year":"1987","journal-title":"Am. 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