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The standard compound, PC 16\u22360\/18\u22362\u2010OOH (synthetic PCOOH), as well as PCOOH from egg yolk, was used. Comparison of the PCOOH concentration in each participant's plasma as determined by use of a Finepak SIL NH<jats:sub>2<\/jats:sub> column with 2\u2010propanol\/methanol\/water as the mobile phase (system A, the conventional method) gave a higher concentration than did an LC\u201018\u2010DB column with methanol containing 0.01% triethylamine (system B). The mean PCOOH concentration for the 43 healthy volunteers was 55.1\u00b130.4 pmol\/mL (mean\u00b1SD) for system A and 16.3\u00b19.9 pmol\/mL for system B. Moreover, the main peak of the plasma extract appeared at a different time from that of synthetic PCOOH or egg yolk PCOOH in system A, whereas in system B plasma sample retention time practically corresponded to that of standard PCOOH. These findings confirm that the PCOOH plasma concentration is not so high as previously reported.<\/jats:p>","DOI":"10.1007\/s11745-004-1311-6","type":"journal-article","created":{"date-parts":[[2006,11,13]],"date-time":"2006-11-13T19:51:16Z","timestamp":1163447476000},"page":"891-896","source":"Crossref","is-referenced-by-count":14,"title":["Phosphatidylcholine hydroperoxide levels in human plasma are lower than previously reported"],"prefix":"10.1002","volume":"39","author":[{"given":"Junko","family":"Adachi","sequence":"first","affiliation":[{"name":"Department of Legal Medicine Kobe University Graduate School of Medicine 7 Kusunoki\u2010cho, Chuo\u2010ku Kobe 650\u20100017 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine Kobe University Graduate School of Medicine 7 Kusunoki\u2010cho, Chuo\u2010ku Kobe 650\u20100017 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rika","family":"Funae","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine Kobe University Graduate School of Medicine 7 Kusunoki\u2010cho, Chuo\u2010ku Kobe 650\u20100017 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Nagasaki","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine Kobe University Graduate School of Medicine 7 Kusunoki\u2010cho, Chuo\u2010ku Kobe 650\u20100017 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaeki","family":"Naito","sequence":"additional","affiliation":[{"name":"Kobe Pharmaceutical University Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine Kobe University Graduate School of Medicine 7 Kusunoki\u2010cho, Chuo\u2010ku Kobe 650\u20100017 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"97","article-title":"Long\u2010Term Ethanol Administration Enhances Age\u2010Dependent Modulation of Redox State in Different Brain Regions in the Rat: Protection by Acetyl Carnitine","volume":"24","author":"Calabrese V.","year":"2002","journal-title":"Int. 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