{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:41:32Z","timestamp":1791171692876,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Staphylococcus aureus<\/jats:italic> causes a variety of human infections including toxic shock syndrome, osteomyelitis, and mastitis. Mastitis is a common disease in the dairy cow, and<jats:italic>S. aureus<\/jats:italic> has been found to be a major infectious organism causing mastitis. The objectives of this research were to determine which FA and esterified forms of FA were inhibitory to growth of<jats:italic>S. aureus<\/jats:italic> bacteria. FA as well as their mono\u2010, di\u2010, and triacylglycerol forms were tested for their ability to inhibit a human toxic shock syndrome clinical isolate (MN8) and two<jats:italic>S. aureus<\/jats:italic> clinical bovine mastitis isolates (305 and Novel). The seven most potent inhibitors across all strains tested by minimum inhibitory concentration analysis included lauric acid, glycerol monolaurate, capric acid, myristic acid, linoleic acid,<jats:italic>cis<\/jats:italic>\u20109,<jats:italic>trans<\/jats:italic>\u201011 conjugated linoleic acid, and<jats:italic>trans<\/jats:italic>\u201010,<jats:italic>cis<\/jats:italic>\u201012 conjugated linoleic acid. Some of these lipids were chosen for 48\u2010h growth curve analysis with a bovine mastitis<jats:italic>S. aureus<\/jats:italic> isolate (Novel) at doses of 0, 20, 50, and 100 \u03bcg\/mL except myristic acid, which was tested at 0, 50, 100, and 200 \u03bcg\/mL. The saturated FA (lauric, capric, myristic) and glycerol monolaurate behaved similarly and reduced overall growth. In contrast, the polyunsaturated FA (linoleic and<jats:italic>cis<\/jats:italic>\u20109,<jats:italic>trans<\/jats:italic>\u201011 conjugated linoleic acid) delayed the time to initiation of exponential growth in a dose\u2010dependent fashion. The results suggest that lipids may be important in the control of<jats:italic>S. aureus<\/jats:italic> during an infection.<\/jats:p>","DOI":"10.1007\/s11745-006-5048-z","type":"journal-article","created":{"date-parts":[[2007,2,5]],"date-time":"2007-02-05T04:00:07Z","timestamp":1170648007000},"page":"951-961","source":"Crossref","is-referenced-by-count":63,"title":["Fatty acids and monoacylglycerols inhibit growth of<i>Staphylococcus aureus<\/i>"],"prefix":"10.1002","volume":"41","author":[{"given":"J. A.","family":"Kelsey","sequence":"first","affiliation":[{"name":"Department of Animal and Veterinary Science University of Idaho 307 Ag Biotech Bldg. Moscow ID 83844\u20102330"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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