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In a single oral dose study in which rats maintained on rodent pellets deficient in \u03c9\u20103 fatty acids were intubated with 0.35 g LSO in lipoid, the amount of ALA present in lymph was increased reaching a maximum concentration of 16.23 mg\/ml at 2.5 h. The amount of ALA present in lymph was increased to a maximum level of 10.95 mg\/ml at 4 h in rats given LSO as a microemulsion in whey protein. When LSO was given without emulsification, the amount of ALA present in lymph was found to reach a maximum level of 7.08 mg\/ml at 6 h. A similar result was observed when weaning rats were intubated with 0.15 g of LSO per day for a period of 60 days. Higher levels of ALA by 41 and 103 % were observed in lymph lipids of rats given microemulsions of LSO in whey protein and in lipoid respectively as compared to rats given LSO without pre\u2010emulsification. Very little conversion of ALA to EPA and DHA was observed in lymph lipids but higher amounts of EPA + DHA was observed in liver and serum of rats given LSO in microemulsion form. This study indicated that ALA concentration in lymph lipids was increased when LSO was given in microemulsion form in lipoid and further conversion to EPA and DHA was facilitated in liver and serum.<\/jats:p>","DOI":"10.1007\/s11745-013-3873-4","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T13:28:45Z","timestamp":1386941325000},"page":"225-233","source":"Crossref","is-referenced-by-count":23,"title":["Lymphatic Transport of \u03b1\u2010Linolenic Acid and Its Conversion to Long Chain n\u20103 Fatty Acids in Rats Fed Microemulsions of Linseed Oil"],"prefix":"10.1002","volume":"49","author":[{"given":"D.","family":"Sugasini","sequence":"first","affiliation":[{"name":"Department of Lipid Science and Traditional Foods CSIR\u2010Central Food Technological Research Institute Mysore 570 020 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. C.","family":"Devaraj","sequence":"additional","affiliation":[{"name":"Department of Drug Metabolism and Pharmacokinetics Jubilant Biosys Bangalore 560 022 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mullangi","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Department of Drug Metabolism and Pharmacokinetics Jubilant Biosys Bangalore 560 022 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. R.","family":"Lokesh","sequence":"additional","affiliation":[{"name":"Department of Lipid Science and Traditional Foods CSIR\u2010Central Food Technological Research Institute Mysore 570 020 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.45.030183.003251"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2008.12.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cocis.2009.11.006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607108314758"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90899.2008"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-012-3731-9"},{"key":"e_1_2_9_8_1","first-page":"1349","article-title":"Techniques for the collection of lymph from the liver, small intestine or thoracic duct of rat","volume":"33","author":"Bollman JL","year":"1948","journal-title":"J Lab Clin Med"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02534914"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-999-0342-3"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1139\/y59-099"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)40190-7"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(80)90269-9"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-013-1736-1"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-6-4"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-003-1341-0"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejlt.200500337"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejlt.201000450"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-010-3427-y"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2012.07.056"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1987.sp003059"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152209788009832"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/61.1.56"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2009.01.001"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/67.1.97"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13228-012-0025-x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451000454X"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.60654"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)41168-X"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2370293"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(88)90256-1"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-010-3464-6"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02664762"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-000-537-7"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)37146-7"}],"container-title":["Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aocs.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s11745-013-3873-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:37:22Z","timestamp":1760960242000},"score":1,"resource":{"primary":{"URL":"https:\/\/aocs.onlinelibrary.wiley.com\/doi\/10.1007\/s11745-013-3873-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,14]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1007\/s11745-013-3873-4"],"URL":"https:\/\/doi.org\/10.1007\/s11745-013-3873-4","archive":["Portico"],"relation":{},"ISSN":["0024-4201","1558-9307"],"issn-type":[{"value":"0024-4201","type":"print"},{"value":"1558-9307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,14]]}}}