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Analyzed comorbidities included chronic obstructive lung disease (COPD), hypertension, coronary artery disease (CAD), peripheral artery disease, myocardial infarction history, diabetes mellitus, renal insufficiency and other malignancies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Most patients (78.9%) had comorbidities, most commonly hypertension (34.1%) followed by COPD (26.4%) and other malignancies (19%). The overall complication rate was 38.6% (26.4% pulmonary; 14.8% cardiac; and 3.0% gastrointestinal). Hypertension (odds ratio (OR)\u2009=\u20091.492\n                      <jats:italic>, p<\/jats:italic>\n                      \u2009=\u20090.031) was associated with more cardiac complications. Heavy smoking (OR\u2009=\u20091.008,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) and low body mass index (BMI) (OR\u2009=\u20090.932\n                      <jats:italic>, p<\/jats:italic>\n                      \u2009&lt;\u20090.001) affected the pulmonary complication rate significantly. None of the included comorbidities affected the overall complication rate or the survival negatively. However, the patient characteristics of advanced age (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), low BMI (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008), and low FEV1 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008) affected the overall complication rate as well as survival (each\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Advanced age, low BMI, and low FEV1 were predictive of greater complication risk and shorter long-term survival in patients who underwent NSCLC resection. Cardiac complications were associated with hypertension and CAD, whereas pulmonary complications were associated with a high pack year count.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11748-021-01710-5","type":"journal-article","created":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T02:28:59Z","timestamp":1632364139000},"page":"248-256","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Impact of preoperative comorbidities on postoperative complication rate and outcome in surgically resected non-small cell lung cancer patients"],"prefix":"10.1007","volume":"70","author":[{"given":"Martina","family":"Benker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Necati","family":"Citak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Neuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Opitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilhan","family":"Inci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,23]]},"reference":[{"key":"1710_CR1","unstructured":"Krebsliga, Krebs in der Schweiz: wichtige Zahlen, 2012\u20132016. 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