{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T17:20:25Z","timestamp":1765041625486,"version":"3.46.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Gen Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Reinterventions after congenital heart disease surgery include not only reoperations but also medical catheter interventions, and the details of these treatment realities are often unclear. This study aimed to elucidate the medical and surgical reinterventions and associated medical costs after the tetralogy of Fallot (TOF) repair using Japanese health insurance claims data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We analyzed reinterventions and medical costs from insurance claims data of patients who underwent TOF repair between 2005 and 2021. Of 174 patients who underwent TOF repair, 23 (13.2%) received a total of 34 reinterventions. These included 23 percutaneous catheter interventions and 11 reoperations. The 5-year reintervention-free rate was 87.5% overall, 94.9% for surgeries with right ventricular outflow tract reconstruction (N\u2009=\u2009130), and 65.6% for surgeries with peripheral pulmonary artery plasty (N\u2009=\u200944). The median (interquartile range) medical cost for patients without reintervention was \u00a55.33 million (4.62\u20137.14 million) and the cost for the patients with reintervention was \u00a5 10.59 million (7.73\u201313.97 million).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Using Japanese insurance claims data, we analyzed the reoperation and catheter intervention after the TOF repair. The reintervention-free rate after TOF repair differed significantly by surgical procedure with a tendency for poorer postoperative prognosis, particularly in cases involving the peripheral pulmonary artery plasty. These analysis results may contribute to predicting outcomes after TOF repair for healthcare professionals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11748-025-02174-7","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T04:09:27Z","timestamp":1750651767000},"page":"902-910","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Reinterventions and medical costs after tetralogy of Fallot repair: a retrospective cohort study using health insurance claims in Japan"],"prefix":"10.1007","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1673-6891","authenticated-orcid":false,"given":"Yasutaka","family":"Hirata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shintaro","family":"Nemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusei","family":"Hamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasumi","family":"Nishiwaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,23]]},"reference":[{"key":"2174_CR1","doi-asserted-by":"publisher","first-page":"e035166","DOI":"10.1161\/JAHA.124.035166","volume":"13","author":"KL Brown","year":"2024","unstructured":"Brown KL, et al. Evaluating long-term outcomes of children undergoing surgical treatment for congenital heart disease for national audit in England and wales. J Am Heart Assoc. 2024;13:e035166.","journal-title":"J Am Heart Assoc"},{"key":"2174_CR2","doi-asserted-by":"publisher","DOI":"10.1007\/s40746-024-00303-7","author":"AC Demianczyk","year":"2024","unstructured":"Demianczyk AC, et al. Optimizing quality of life in children with complex congenital heart disease. Curr Treat Options Pediatr. 2024. https:\/\/doi.org\/10.1007\/s40746-024-00303-7.","journal-title":"Curr Treat Options Pediatr"},{"key":"2174_CR3","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1253\/circj.CJ-22-0134","volume":"86","author":"H Ohuchi","year":"2022","unstructured":"Ohuchi H, et al. JCS 2022 guideline on management and re-interventional therapy in patients with congenital heart disease long-term after initial repair. Circ J. 2022;86:1591\u2013690.","journal-title":"Circ J"},{"key":"2174_CR4","doi-asserted-by":"publisher","first-page":"2855","DOI":"10.1253\/circj.CJ-12-0208","volume":"76","author":"A Miyazaki","year":"2012","unstructured":"Miyazaki A, et al. Efficacy of hemodynamic-based management of tachyarrhythmia after repair of tetralogy of Fallot. Circ J. 2012;76:2855\u201362.","journal-title":"Circ J"},{"key":"2174_CR5","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1177\/0218492320981501","volume":"29","author":"Y Hirata","year":"2021","unstructured":"Hirata Y, et al. Status of cardiovascular surgery in Japan: a report based on the Japan cardiovascular surgery database 2017\u20132018. 1. congenital heart surgery. Asian Cardiovasc Thorac Ann. 2021;29:289\u201393.","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"2174_CR6","doi-asserted-by":"publisher","first-page":"2434","DOI":"10.1016\/j.jacc.2018.03.491","volume":"71","author":"LG Spector","year":"2018","unstructured":"Spector LG, et al. Trends in long-term mortality after congenital heart surgery. J Am Coll Cardiol. 2018;71:2434\u201346.","journal-title":"J Am Coll Cardiol"},{"key":"2174_CR7","doi-asserted-by":"publisher","first-page":"233","DOI":"10.31662\/jmaj.2022-0184","volume":"6","author":"M Suto","year":"2023","unstructured":"Suto M, et al. Studies of health insurance claims data in Japan: a scoping review. JMA J. 2023;6:233\u201345.","journal-title":"JMA J"},{"key":"2174_CR8","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1248\/yakushi.21-00178-3","volume":"142","author":"Y Takekuma","year":"2022","unstructured":"Takekuma Y, Imai S, Sugawara M. Clinical research using the large health insurance claims database. Yakugaku Zasshi. 2022;142:331\u20136.","journal-title":"Yakugaku Zasshi"},{"key":"2174_CR9","first-page":"91","volume":"39","author":"S Nemoto","year":"2023","unstructured":"Nemoto S, et al. National survey by the Japanese society of pediatric cardiology and cardiac surgery for an overview of re-interventions after surgical reconstruction of the right ventricular outflow tract and\/or pulmonary artery and an estimation of their medical cost. Nihon Shoni Junkanki Gakkai Zasshi. 2023;39:91\u20138.","journal-title":"Nihon Shoni Junkanki Gakkai Zasshi"},{"key":"2174_CR10","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1002\/jgf2.422","volume":"22","author":"K Nagai","year":"2021","unstructured":"Nagai K, et al. Data resource profile: JMDC claims database sourced from health insurance societies. J Gen Fam Med. 2021;22:118\u201327.","journal-title":"J Gen Fam Med"}],"container-title":["General Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11748-025-02174-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11748-025-02174-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11748-025-02174-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T10:41:11Z","timestamp":1765017671000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11748-025-02174-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,23]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["2174"],"URL":"https:\/\/doi.org\/10.1007\/s11748-025-02174-7","relation":{},"ISSN":["1863-6705","1863-6713"],"issn-type":[{"type":"print","value":"1863-6705"},{"type":"electronic","value":"1863-6713"}],"subject":[],"published":{"date-parts":[[2025,6,23]]},"assertion":[{"value":"9 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Yusei Hamada, Yasumi Nishiwaki, and Kosuke Kikuchi are employees of Teijin Limited. Akihiro Nakajima is an employee of Teijin Pharma Limited. Shintaro Nemoto reports a consulting relationship with Teijin Ltd. The other author declares no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}