{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T20:50:13Z","timestamp":1784580613519,"version":"3.55.0"},"reference-count":20,"publisher":"Jaypee Brothers Medical Publishing","issue":"2","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"South African Orthopaedic Association","award":["2014"],"award-info":[{"award-number":["2014"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,8,31]]},"DOI":"10.1007\/s11751-016-0259-1","type":"journal-article","created":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T10:57:25Z","timestamp":1467370645000},"page":"135-142","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The outcome of treatment of chronic osteomyelitis according to an integrated approach"],"prefix":"10.5005","volume":"11","author":[{"given":"Leonard C.","family":"Marais","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Aldous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theo L. B.","family":"Le Roux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2914","published-online":{"date-parts":[[2016,7,1]]},"reference":[{"key":"ref=1","doi-asserted-by":"crossref","unstructured":"1. Galanakos SP, Papadakis SA, Kateros K, Papakostas I, Macheras G (2009) Biofilm and orthopaedic practice: the world of microbes in a world of implants. Orthop Trauma 23(3):175-179","DOI":"10.1016\/j.mporth.2009.02.002"},{"key":"ref=2","doi-asserted-by":"crossref","unstructured":"2. Boyce BF, Xing L, Schwarz EM (2011) The role of the immune system and bone cells in acute and chronic osteomyelitis. In: Lorenzo J, Choi Y, Horowitz M, Takayanagi H (eds) Osteoimmunology: interactions of the immune and skeletal systems, 1st edn. Academic Press, Waltham, pp 369-390","DOI":"10.1016\/B978-0-12-375670-1.10013-5"},{"key":"ref=3","doi-asserted-by":"crossref","unstructured":"3. Walter G, Kemmerer M, Kappler C, Hoffmann R (2012) Treatment algorithms for chronic osteomyelitis. Dtsch Arztebl Int 109(14):257-264","DOI":"10.3238\/arztebl.2012.0257"},{"key":"ref=4","unstructured":"4. Marais LC, Ferreira N, Aldous C, Le Roux TLB (2014) Classification of chronic osteomyeltis. S Afr J Orthop 13(1):22-28"},{"key":"ref=5","doi-asserted-by":"crossref","unstructured":"5. Roa N, Ziran BH, Lipsky BA (2011) Treating osteomyelitis: antibiotics and surgery. Plast Reconstr Surg 127(Suppl):177S- 187S","DOI":"10.1097\/PRS.0b013e3182001f0f"},{"key":"ref=6","doi-asserted-by":"crossref","unstructured":"6. Roman\u00f2 CL, Roman\u00f2 D, Logoluso N, Drago L (2011) Bone and joint infections in adults: a comprehensive classification proposal. Eur Orthop Traumatol 1:207-217","DOI":"10.1007\/s12570-011-0056-8"},{"key":"ref=7","doi-asserted-by":"crossref","unstructured":"7. Cierny G, Mader JT, Penninck JJ (2003) A clinical staging system for adult osteomyelitis. Clin Orthop Relat Res 414:7-24","DOI":"10.1097\/01.blo.0000088564.81746.62"},{"key":"ref=8","doi-asserted-by":"crossref","unstructured":"8. Lazzarini L, Lipsky BA, Mader JT (2005) Antibiotic treatment of osteomyelitis: what have we learned from 30 years of clinical trials? Int J Infect Dis 9:127-138","DOI":"10.1016\/j.ijid.2004.09.009"},{"key":"ref=9","doi-asserted-by":"crossref","unstructured":"9. McNally M, Nagarajah K (2010) Osteomyelitis. Orthop Trauma 24(6):416-429","DOI":"10.1016\/j.mporth.2010.09.004"},{"key":"ref=10","doi-asserted-by":"crossref","unstructured":"10. Cierny G (2011) Surgical treatment of osteomyelitis. Plast Reconstr Surg 127(Suppl 1):S190-S204","DOI":"10.1097\/PRS.0b013e3182025070"},{"key":"ref=11","doi-asserted-by":"crossref","unstructured":"11. Lazzarini L, Mader JT, Calhoun JH (2004) Osteomyelitisin Long Bones. J Bone Jt Surg Am 86(10):2305-2318","DOI":"10.2106\/00004623-200410000-00028"},{"key":"ref=12","doi-asserted-by":"crossref","unstructured":"12. Beaton DE, Wright JG, Katz JN, the Upper Extremity Collaborative Group (2005) Development of the QuickDASH: comparison of three item-reduction approaches. J Bone Jt Surg Am 87(5):1038-1046","DOI":"10.2106\/JBJS.D.02060"},{"key":"ref=13","doi-asserted-by":"crossref","unstructured":"13. Johanson NA, Liang MH, Daltroy L, Rudicel S, Richmond J (2004) American academy of orthopaedic surgeons lower limb outcomes assessment instruments. Reliability, validity, and sensitivity to change. J Bone Jt Surg Am 86(5):902-909","DOI":"10.2106\/00004623-200405000-00003"},{"key":"ref=14","doi-asserted-by":"crossref","unstructured":"14. Cierny G, DiPasquale D (2002) Periprosthetic total joint infections. Staging, treatment, and outcomes. Clin Orthop Relat Res 403:23-28","DOI":"10.1097\/00003086-200210000-00005"},{"key":"ref=15","unstructured":"15. Lautenbach E (1975) Chronic Osteomyelitis: irrigation and suction after surgery. J Bone Jt Surg Br 57(2):259"},{"key":"ref=16","doi-asserted-by":"crossref","unstructured":"16. Hashmi MA, Norman P, Saleh M (2004) The management of chronic osteomyelitis using the Lautenbach method. J Bone Jt Surg Br 86:269-275","DOI":"10.1302\/0301-620X.86B2.14011"},{"key":"ref=17","doi-asserted-by":"crossref","unstructured":"17. Hall BB, Fitzgerald RH, Rosenblatt JE (1984) Anaerobic osteomyelitis. J Bone Jt Surg Am 65:30-35","DOI":"10.2106\/00004623-198365010-00005"},{"key":"ref=18","doi-asserted-by":"crossref","unstructured":"18. Conterno L, Turchi MD (2013) Antibiotics for treating chronic osteomyelitis in adults. Cochrane Database Syst Rev. doi:10.1002\/14651858.CD004439.pub3","DOI":"10.1002\/14651858.CD004439.pub3"},{"key":"ref=19","doi-asserted-by":"crossref","unstructured":"19. Marais LC, Ferreira N, Sartorius B, Aldous C, Le Roux TLB (2015) A modified staging system for chronic osteomyelitis. J Orthop 12:184-192. doi:10.1016\/j.jor.2015.05.017","DOI":"10.1016\/j.jor.2015.05.017"},{"key":"ref=20","doi-asserted-by":"crossref","unstructured":"20. Sheehy SH, Atkins BA, Bejon P, Byren I, Wyllie D, Athanasou NA et al (2010) The microbiology of chronic osteomyelitis: prevalence of resistance to common empirical anti-microbial regimens. J Infect 60:338-343","DOI":"10.1016\/j.jinf.2010.03.006"}],"container-title":["Strategies in Trauma and Limb Reconstruction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11751-016-0259-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11751-016-0259-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.stlrjournal.com\/doi\/pdf\/10.1007\/s11751-016-0259-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T18:28:52Z","timestamp":1622744932000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.stlrjournal.com\/doi\/10.1007\/s11751-016-0259-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,1]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016]]}},"alternative-id":["10.1007\/s11751-016-0259-1"],"URL":"https:\/\/doi.org\/10.1007\/s11751-016-0259-1","relation":{},"ISSN":["1828-8936","1828-8928"],"issn-type":[{"value":"1828-8936","type":"print"},{"value":"1828-8928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,1]]}}}