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We compared two cognitive rehabilitation programs to a control group in cancer survivors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Study population were adult cancer survivors with cognitive symptoms 6\u201360\u00a0months after adjuvant chemotherapy. Participants randomised to: Attention Process Training (APT), Compensatory Strategy Training (CST), or control group. Active interventions comprised 6\u2013week, 2\u2013h\/week small group sessions. Assessments: pre- and post-intervention, 6- and 12-months later. Primary outcome was change in cognitive symptoms (FACT-COG-PCI subscale) between baseline and post-intervention. Secondary endpoints included objective neuropsychological performance, Functional Impact Assessment (FIA), patient-reported outcome measures, and associations. Analyses were on an intention-to-treat basis. Analysis of covariance mixed models were used for continuous outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty-five participants were randomised (APT <jats:italic>n<\/jats:italic>\u2009=\u200921; CST <jats:italic>n<\/jats:italic>\u2009=\u200924; controls <jats:italic>n<\/jats:italic>\u2009=\u200920): 94% breast cancer, median age 54. Median time since chemotherapy 20.7\u00a0months. FACT-COG-PCI, clinical neuropsychological <jats:italic>T<\/jats:italic>-scores, and FIA improved in all groups over time, but no significant differences between arms. On mean neuropsychological <jats:italic>T<\/jats:italic>-scores 19\/65 (29%) were impaired at baseline; post-intervention impairment controls 31.3%, CST 16.7%, APT 20.0%. On FIA at baseline, nine were impaired; this decreased to three post-intervention (one\/group). FACT-COG-PCI was weakly associated with neuropsychological tests (rho\u2009=\u20090.24, <jats:italic>p<\/jats:italic>\u2009=\u20090.051) at baseline, and had no association with FIA. Neuropsychological total mean <jats:italic>T<\/jats:italic>-score was moderately positively associated with FIA (rho\u2009=\u20090.37, <jats:italic>p<\/jats:italic>\u2009=\u20090.003).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>There were no significant differences between intervention groups and controls using linear mixed models adjusted for baseline scores.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Implications for Cancer Survivors<\/jats:title>\n                <jats:p>Cognitive symptoms and neuropsychological test scores improve over time.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11764-022-01261-5","type":"journal-article","created":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T01:02:23Z","timestamp":1665795743000},"page":"1583-1595","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["A randomised controlled trial evaluating two cognitive rehabilitation approaches for cancer survivors with perceived cognitive impairment"],"prefix":"10.1007","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5739-5790","authenticated-orcid":false,"given":"Janette L.","family":"Vardy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory R.","family":"Pond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie L.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrinne","family":"Renton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Dixon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haryana M.","family":"Dhillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,15]]},"reference":[{"key":"1261_CR1","doi-asserted-by":"crossref","unstructured":"Boykoff N, Moieni M, Subramanian SK. 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