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This study examines the relationship between various adiposity measures\u2014body mass index (BMI), waist circumference, waist-to-hip ratio (WHR), percentage body fat (BF), and fat mass index (FMI)\u2014and QoL in Black BC survivors participating in the Women\u2019s Circle of Health Follow-Up Study, a New Jersey-based population cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed data from 785 women aged 20\u201375, diagnosed with BC between 2012 and 2019. Participants completed interviews approximately 10\u00a0months (visit 1) and 24\u00a0months (visit 2) post-diagnosis. Adiposity measures were recorded at visit 1, while QoL was evaluated at visit 2 using the Functional Assessment of Cancer Therapy\u2013Breast (FACT-B) overall score and subscales (physical, emotional, functional, social well-being, and BC-specific subscale). Multivariable robust Poisson regression models were used to estimate risk ratios for the association between adiposity and QoL, dichotomized as low\/high based on sample medians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      High levels of general and central obesity were prevalent (58% and 75%, respectively). Women with BMI\u2009\u2265\u200940\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      had a 54% higher risk of lower overall QoL compared to those with BMI 18.5\u201324.9 (RR, 1.54; 95% CI, 1.19\u20132.00). Elevated risk of low QoL was also observed for higher quartiles of waist circumference, BF, and FMI, primarily in physical well-being and BC-specific subscales.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher adiposity is significantly associated with lower QoL among Black BC survivors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for Cancer Survivors<\/jats:title>\n                    <jats:p>Maintaining a healthy weight may support long-term QoL in Black BC survivors.\u00a0<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11764-025-01829-x","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T03:57:31Z","timestamp":1754452651000},"page":"916-930","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prospective associations of adiposity with health-related quality of life during breast cancer survivorship among Black women"],"prefix":"10.1007","volume":"20","author":[{"given":"Carola T.","family":"S\u00e1nchez-D\u00edaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur","family":"Zeinomar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hari S.","family":"Iyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marley","family":"Perlstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen S.","family":"Pawlish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitaw","family":"Demissie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Chen","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa V.","family":"Bandera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"key":"1829_CR1","first-page":"17","volume":"73","author":"RL Siegel","year":"2023","unstructured":"Siegel RL, Miller KD, Wagle NS, et al. 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