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This scoping review examined (1) associations between SB and health outcomes and (2) intervention studies to reduce SB among childhood and AYA cancer patients and survivors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A search of five databases (PubMed, Embase, Web of Science, CINAHL, SportDiscus) was finalized in May 2025. Studies were included if\u2009\u2265\u200950% of participants were\u2009\u2264\u200939\u00a0years old and treated for cancer, and SB was measured via device or self-report. Observational studies had to report associations of SB with health outcomes; intervention studies had to report results for SB-related aims. Risk of bias and quality assessments were performed using established tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-four studies (16 observational, 8 interventional) met criteria. Observational studies identified associations between SB and adverse cardiometabolic, bone, and patient-reported outcomes; none assessed mortality. All interventions primarily targeted physical activity, not SB reduction; three showed modest, short-term SB decreases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early evidence suggests SB is associated with multiple adverse health outcomes in youth treated for cancer, while current interventions without an SB-specific focus have minimal impact. Key research gaps include the absence of longitudinal data, standardized SB measurement, and randomized controlled trials testing SB-focused strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for Cancer Survivors<\/jats:title>\n                    <jats:p>Reducing SB may help mitigate health risks in childhood and AYA cancer survivors. More robust epidemiologic evidence and targeted interventions are needed to address this modifiable behavior.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11764-025-01908-z","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T09:24:22Z","timestamp":1762853062000},"page":"2685-2709","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Sedentary behavior in children, adolescents, and young adults treated for cancer: A scoping review of health outcomes and interventions"],"prefix":"10.1007","volume":"20","author":[{"given":"Brittany J.","family":"Ivory","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer E.","family":"Dinalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina S.","family":"Kadan-Lottick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina M.","family":"Dieli-Conwright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etan","family":"Orgel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten K.","family":"Ness","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Freyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britni R.","family":"Belcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"1908_CR1","unstructured":"National Cancer Institute. 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