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Hospitalizations for relevant medical conditions were identified through national hospital admission data. Survivors and controls were followed through December 2021. Hospitalization incidence rate ratios (IRRs) and cumulative incidences were calculated, with IRRs stratified by tumour type and therapy (chemotherapy, radiotherapy).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AYA cancer survivors had a significantly increased IRR of hospitalization for any medical condition (adjusted IRR 1.73; 95% CI 1.64 to 1.82), as well as for most individual conditions. The cumulative incidence of hospitalization for any medical condition was 25.4% at 25\u00a0years post-index, with most individual conditions below 5%. Most tumour subgroups had significantly increased IRRs compared to controls, with the highest IRRs observed for Hodgkin lymphoma and leukaemia. In general, elevated IRRs were more pronounced among survivors who received chemotherapy or radiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>AYA cancer survivors have an increased risk of hospitalization for most medical conditions compared to AYAs without a cancer history, though absolute long-term risk is low. As hospital admissions reflect only part of the clinical and societal burden, the findings may underestimate the total impact of late effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for Cancer Survivors<\/jats:title>\n                    <jats:p>AYA cancer survivors may benefit from long-term, risk-based survivorship care focused on early detection and management of late effects, especially after chemotherapy and radiotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11764-026-01996-5","type":"journal-article","created":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T08:02:49Z","timestamp":1772870569000},"page":"1649-1660","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hospitalization for medical conditions in adolescent and young adult cancer survivors: a nationwide cohort study using the Netherlands Cancer Registry"],"prefix":"10.1007","volume":"20","author":[{"given":"Annemiek S.","family":"Lieffering","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal R. 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