{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T16:27:34Z","timestamp":1780676854092,"version":"3.54.1"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,7,30]],"date-time":"2018-07-30T00:00:00Z","timestamp":1532908800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ir J Med Sci"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1007\/s11845-018-1864-4","type":"journal-article","created":{"date-parts":[[2018,7,30]],"date-time":"2018-07-30T04:27:40Z","timestamp":1532924860000},"page":"415-424","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prognostic analysis and liver metastases relevant factors after gastric and hepatic surgical treatment in gastric cancer patients with metachronous liver metastases: a population-based study"],"prefix":"10.1007","volume":"188","author":[{"given":"Yibin","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulian","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,30]]},"reference":[{"key":"1864_CR1","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1093\/carcin\/bgp263","volume":"31","author":"MJ Thun","year":"2010","unstructured":"Thun MJ, DeLancey JO, Center MM, Center MM, Jemal A, Ward EM (2010) The global burden of cancer: priorities for prevention. Carcinogenesis 31:100\u2013110","journal-title":"Carcinogenesis"},{"key":"1864_CR2","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3322\/caac.20107","volume":"61","author":"A Jemal","year":"2011","unstructured":"Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69\u201390","journal-title":"CA Cancer J Clin"},{"key":"1864_CR3","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1001\/jama.1991.03460100089030","volume":"265","author":"WJ Blot","year":"1991","unstructured":"Blot WJ, Devesa SS, Kneller RW, Fraumeni JF Jr (1991) Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 265:1287\u20131289","journal-title":"JAMA"},{"key":"1864_CR4","doi-asserted-by":"publisher","first-page":"2137","DOI":"10.1200\/JCO.2005.05.2308","volume":"24","author":"F Kamangar","year":"2006","unstructured":"Kamangar F, Dores GM, Anderson WF (2006) Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 24:2137\u20132150","journal-title":"J Clin Oncol"},{"key":"1864_CR5","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1097\/01.sla.0000143245.28656.15","volume":"240","author":"M D\u2019Angelica","year":"2004","unstructured":"D\u2019Angelica M, Gonen M, Brennan MF, Turnbull AD, Bains M, Karpeh MS (2004) Patterns of initial recurrence in completely resected gastric adenocarcinoma. Ann Surg 240:808\u2013816","journal-title":"Ann Surg"},{"key":"1864_CR6","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1002\/jso.20739","volume":"95","author":"Y Sakamoto","year":"2007","unstructured":"Sakamoto Y, Sano T, Shimada K, Esaki M, Saka M, Fukagawa T et al (2007) Favorable indications for hepatectomy in patients with liver metastasis from gastric cancer. J Surg Oncol 95:534\u2013539","journal-title":"J Surg Oncol"},{"key":"1864_CR7","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.ejso.2008.12.017","volume":"35","author":"GA Tiberio","year":"2009","unstructured":"Tiberio GA, Coniglio A, Marchet A, Marrelli D, Giacopuzzi S, Baiocchi L et al (2009) Metachronous hepatic metastases from gastric carcinoma: a multicentric survey. Eur J Surg Oncol 35:486\u2013491","journal-title":"Eur J Surg Oncol"},{"key":"1864_CR8","first-page":"E241","volume":"52","author":"M Slupski","year":"2009","unstructured":"Slupski M, Wlodarczyk Z, Jasinski M, Masztalerz M, Tujakowski J (2009) Outcomes of simultaneous and delayed resections of synchronous colorectal liver metastases. Can J Surg 52:E241\u2013E244","journal-title":"Can J Surg"},{"key":"1864_CR9","first-page":"1062","volume":"49","author":"A Saiura","year":"2002","unstructured":"Saiura A, Umekita N, Inoue S, Maeshiro T, Miyamoto S, Matsui Y et al (2002) Clinicopathological features and outcome of hepatic resection for liver metastasis from gastric cancer. Hepato-Gastroenterology 49:1062\u20131065","journal-title":"Hepato-Gastroenterology"},{"key":"1864_CR10","first-page":"1309","volume":"28","author":"C Kunisaki","year":"2008","unstructured":"Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Fujii S et al (2008) Impact of palliative gastrectomy in patients with incurable advanced gastric cancer. Anticancer Res 28:1309\u20131315","journal-title":"Anticancer Res"},{"key":"1864_CR11","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1093\/annonc\/mdn026","volume":"19","author":"SH Cheon","year":"2008","unstructured":"Cheon SH, Rha SY, Jeung HC, Im CK, Kim SH, Kim HR et al (2008) Survival benefit of combined curative resection of the stomach (D2 resection) and liver in gastric cancer patients with liver metastases. Ann Oncol 19:1146\u2013I 153","journal-title":"Ann Oncol"},{"key":"1864_CR12","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1067\/msy.2003.147","volume":"133","author":"Y Sakamoto","year":"2003","unstructured":"Sakamoto Y, Ohyama S, Yamamoto J, Yamaka K, Seki M, Ohta K et al (2003) Surgical resection of liver metastases of gastric cancer: an analysis of a 17-year experience with 22 patients. Surgery 133:507\u2013511","journal-title":"Surgery"},{"issue":"Suppl 3","key":"1864_CR13","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1634\/theoncologist.10-90003-49","volume":"10","author":"JA Ajani","year":"2005","unstructured":"Ajani JA (2005) Evolving chemotherapy for advanced gastric cancer. Oncologist 10(Suppl 3):49\u201358","journal-title":"Oncologist"},{"key":"1864_CR14","doi-asserted-by":"publisher","first-page":"135","DOI":"10.5230\/jgc.2011.11.3.135","volume":"11","author":"A Shin","year":"2011","unstructured":"Shin A, Kim J, Park S (2011) Gastric cancer epidemiology in Korea. J Gastric Cancer 11:135\u2013140","journal-title":"J Gastric Cancer"},{"key":"1864_CR15","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1007\/s11605-009-1095-0","volume":"14","author":"C Li","year":"2010","unstructured":"Li C, Yan M, Chen J, Xiang M, Zhu ZG, Yin HR et al (2010) Survival benefit of non-curative gastrectomy for gastric cancer patients with synchronous distant metastasis. J Gastrointest Surg 14:282\u2013288","journal-title":"J Gastrointest Surg"},{"key":"1864_CR16","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/S1091-255X(01)00075-0","volume":"6","author":"J Zacherl","year":"2002","unstructured":"Zacherl J, Zacherl M, Scheuba C, Steininger R, Wenzl E, M\u00fchlbacher F et al (2002) Analysis of hepatic resection of metastasis originating from gastric adenocarcinoma. J Gastrointest Surg 6:682\u2013689","journal-title":"J Gastrointest Surg"},{"key":"1864_CR17","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1097\/SLA.0000000000001542","volume":"263","author":"SR Markar","year":"2016","unstructured":"Markar SR, Mikhail S, Malietzis G, Athanasiou T, Mariette C, Sasako M et al (2016) Influence of surgical resection of hepatic metastases from gastric adenocarcinoma on long-term survival: systematic review and pooled analysis. Ann Surg 263:1092\u20131101","journal-title":"Ann Surg"},{"key":"1864_CR18","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1007\/s12072-009-9161-y","volume":"4","author":"H Tsujimoto","year":"2010","unstructured":"Tsujimoto H, Ichikura T, Ono S, Suqasawa H, Hiraki S, Sakamoto N et al (2010) Outcomes for patients following hepatic resection of metastatic tumors from gastric cancer. Hepatol Int 4:406\u2013413","journal-title":"Hepatol Int"},{"key":"1864_CR19","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.jamcollsurg.2003.08.013","volume":"198","author":"D Marrelli","year":"2004","unstructured":"Marrelli D, Roviello F, De Stefano A, Fotia G, Giliberto C, Garosi L et al (2004) Risk factors for liver metastases after curative surgical procedures for gastric cancer: a prospective study of 208 patients treated with surgical resection. J Am Coll Surg 198:51\u201358","journal-title":"J Am Coll Surg"},{"key":"1864_CR20","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1007\/s00423-012-0959-z","volume":"397","author":"N Takemura","year":"2012","unstructured":"Takemura N, Saiura A, Koga R, Arita J, Yoshioka R, Ono Y et al (2012) Long-term outcomes after surgical resection for gastric cancer liver metastasis: an analysis of 64 macroscopically complete resections. Langenbeck's Arch Surg 397:951\u2013957","journal-title":"Langenbeck's Arch Surg"},{"key":"1864_CR21","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1007\/PL00011738","volume":"4","author":"K Kumagai","year":"2001","unstructured":"Kumagai K, Tanaka T, Yamagata K, Yokoyama N, Shimizu K (2001) Liver metastasis in gastric cancer with particular reference to lymphatic advancement. Gastric Cancer 4:150\u2013155","journal-title":"Gastric Cancer"},{"key":"1864_CR22","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1002\/jso.2930360405","volume":"36","author":"S Koga","year":"1987","unstructured":"Koga S, Takebayashi M, Kaibara N, Nishidoi H, Kimura O, Kawasumi H et al (1987) Pathological characteristics of gastric cancer that develop hematogenous recurrence, with special reference to the site of recurrence. J Surg Oncol 36:239\u2013242","journal-title":"J Surg Oncol"},{"key":"1864_CR23","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1002\/bjs.1800790320","volume":"79","author":"Y Maehara","year":"1992","unstructured":"Maehara Y, Orita H, Okuyama T, Moriguchi S, Tsujitani S, Korenaga D et al (1992) Predictors of lymph node metastasis in early gastric cancer. Br J Surg 79:245\u2013247","journal-title":"Br J Surg"},{"key":"1864_CR24","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S0039-6060(99)70265-5","volume":"125","author":"H Saito","year":"1999","unstructured":"Saito H, Tsujitani S, Kondo A, Ikeguchi M, Maeta M, Kaibara N (1999) Expression of vascular endothelial growth factor correlates with hematogenous recurrence in gastric carcinoma. Surgery 125:195\u2013201","journal-title":"Surgery"},{"key":"1864_CR25","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1007\/BF02573892","volume":"9","author":"WJ Hyung","year":"2002","unstructured":"Hyung WJ, Lee JH, Choi SH, Min JS, Noh SH (2002) Prognostic impact of lymphatic and\/or blood vessel invasion in patients with node-negative advanced gastric cancer. Ann Surg Oncol 9:562\u2013567","journal-title":"Ann Surg Oncol"},{"key":"1864_CR26","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1097\/01.sla.0000194087.96582.3e","volume":"243","author":"BJ Dicken","year":"2006","unstructured":"Dicken BJ, Graham K, Hamilton SM, Andrews S, Lai R, Listgarten J (2006) Lymphovascular invasion is associated with poor survival in gastric cancer: an application of gene-expression and tissue array techniques. Ann Surg 243:64\u201373","journal-title":"Ann Surg"},{"key":"1864_CR27","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1097\/00000658-200201000-00011","volume":"235","author":"K Okano","year":"2002","unstructured":"Okano K, Maeba T, Ishimura K, Karasawa Y, Goda F, Wakabayashi H et al (2002) Hepatic resection for metastatic tumors from gastric cancer. Ann Surg 235:86\u201391","journal-title":"Ann Surg"},{"key":"1864_CR28","first-page":"1527","volume":"51","author":"CM Kwok","year":"2004","unstructured":"Kwok CM, Wu CW, Lo SS, Shen KH, Hsieh MC, Lui WY (2004) Survival of gastric cancer with concomitant liver metastases. Hepato-Gastroenterology 51:1527\u20131530","journal-title":"Hepato-Gastroenterology"},{"key":"1864_CR29","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1002\/jso.20328","volume":"95","author":"S Lim","year":"2007","unstructured":"Lim S, Muhs BE, Marcus SG, Newman E, Berman RS, Hiotis SP (2007) Results following resection for stage IV gastric cancer; are better outcomes observed in selected patient subgroups? J Surg Oncol 95:118\u2013122","journal-title":"J Surg Oncol"},{"key":"1864_CR30","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s00423-008-0311-9","volume":"394","author":"K Ueda","year":"2009","unstructured":"Ueda K, Iwahashi M, Nakamori M, Nakamura M, Naka T, Ishida K et al (2009) Analysis of the prognostic factors and evaluation of surgical treatment for synchronous liver metastases from gastric cancer. Langenbeck's Arch Surg 394:647\u2013653","journal-title":"Langenbeck's Arch Surg"},{"key":"1864_CR31","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s00423-008-0398-z","volume":"394","author":"H Saito","year":"2009","unstructured":"Saito H, Yamada Y, Tsujitani S, Ikequchi M (2009) Clinicopathologic characteristics of gastric cancer patients who underwent noncurative gastrectomy with long-term survival. Langenbeck's Arch Surg 394:99\u2013103","journal-title":"Langenbeck's Arch Surg"},{"key":"1864_CR32","first-page":"1238","volume":"55","author":"Z Morise","year":"2008","unstructured":"Morise Z, Sugioka A, Hoshimoto S, Kato T, Ikeda M, Uyama I et al (2008) The role of hepatectomy for patients with liver metastases of gastric cancer. Hepato-Gastroenterology 55:1238\u20131241","journal-title":"Hepato-Gastroenterology"},{"key":"1864_CR33","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1097\/01.mog.0000179833.28158.b7","volume":"21","author":"T Leong","year":"2005","unstructured":"Leong T (2005) Chemotherapy and radiotherapy in the management of gastric cancer. Curr Opin Gastroenterol 21:673\u2013678","journal-title":"Curr Opin Gastroenterol"},{"key":"1864_CR34","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1111\/j.1445-2197.2006.03649.x","volume":"76","author":"I Samarasam","year":"2006","unstructured":"Samarasam I, Chandran BS, Sitaram V, Perakath B, Nair A, Mathew G (2006) Palliative gastrectomy in advanced gastric cancer: is it worthwhile? ANZ J Surg 76:60\u201363","journal-title":"ANZ J Surg"},{"key":"1864_CR35","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1093\/jjco\/hym113","volume":"37","author":"R Koga","year":"2007","unstructured":"Koga R, Yamamoto J, Ohyama S, Saiura A, Seki M, Seto Y et al (2007) Liver resection for metastatic gastric cancer: experience with 42 patients including eight long-term survivors. Jpn J Clin Oncol 37:836\u2013842","journal-title":"Jpn J Clin Oncol"},{"key":"1864_CR36","first-page":"2379","volume":"28","author":"H Miyagaki","year":"2008","unstructured":"Miyagaki H, Fujitani K, Tsujinaka T, Hirao M, Yasui M, Kashiwazaki M et al (2008) The significance of gastrectomy in advanced gastric cancer patients with non-curative factors. Anticancer Res 28:2379\u20132384","journal-title":"Anticancer Res"},{"key":"1864_CR37","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1007\/s00268-009-0034-2","volume":"33","author":"SE Hwang","year":"2009","unstructured":"Hwang SE, Yang DH, Kim CY (2009) Prognostic factors for survival in patients with hepatic recurrence after curative resection of gastric cancer. World J Surg 33:1468\u20131472","journal-title":"World J Surg"},{"key":"1864_CR38","first-page":"367","volume":"105","author":"T Hirasawa","year":"2008","unstructured":"Hirasawa T, Asahara S, Fujisaki S, Kuraoka K, Takano K, Kamei A et al (2008) Transcatheter arterial chemoembolization (TACE) using degradable starch microspheres (DSM) for metastatic liver tumors in patients with gastric cancer. Nippon Shokakibyo Gakkai Zasshi 105:367\u2013372","journal-title":"Nippon Shokakibyo Gakkai Zasshi"}],"container-title":["Irish Journal of Medical Science (1971 -)"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-018-1864-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11845-018-1864-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-018-1864-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T14:45:25Z","timestamp":1568040325000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11845-018-1864-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,30]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["1864"],"URL":"https:\/\/doi.org\/10.1007\/s11845-018-1864-4","relation":{},"ISSN":["0021-1265","1863-4362"],"issn-type":[{"value":"0021-1265","type":"print"},{"value":"1863-4362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,30]]},"assertion":[{"value":"20 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was reviewed and approved by the ethical committee of the Second Affiliated Hospital, School of Medicine, Zhejiang University. All patients were followed up by phone call or SMS and explained clearly that data collected will be intended for publication. All methods were performed in accordance with the relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}