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None of the above charities or funding bodies had any influence on the conduct of this study, or had any influence on the decision to submit the final manuscript for publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the institutional audit board of Beaumont Hospital, Dublin, Ireland.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}