{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T17:34:21Z","timestamp":1782322461646,"version":"3.54.5"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ir J Med Sci"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s11845-022-03230-4","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T05:03:07Z","timestamp":1669006987000},"page":"2331-2335","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["What is the role of breast MRI in the management of women with pathologic nipple discharge and normal conventional imaging?"],"prefix":"10.1007","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7169-5933","authenticated-orcid":false,"given":"Aydan","family":"Avdan Aslan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6349-3998","authenticated-orcid":false,"given":"Serap","family":"G\u00fcltekin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"3230_CR1","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1111\/j.1754-9485.2011.02294.x","volume":"55","author":"JH Seow","year":"2011","unstructured":"Seow JH, Metcalf C, Wylie E (2011) Nipple discharge in a screening programme: imaging findings with pathological correlation. J Med Imaging Radiat Oncol 55:577\u2013586. https:\/\/doi.org\/10.1111\/j.1754-9485.2011.02294.x","journal-title":"J Med Imaging Radiat Oncol"},{"key":"3230_CR2","doi-asserted-by":"publisher","first-page":"203","DOI":"10.2214\/AJR.14.13354","volume":"205","author":"M Bahl","year":"2015","unstructured":"Bahl M, Baker JA, Greenup RA et al (2015) Diagnostic value of ultrasound in female patients with nipple discharge. AJR Am J Roentgenol 205:203\u2013208. https:\/\/doi.org\/10.2214\/AJR.14.13354","journal-title":"AJR Am J Roentgenol"},{"key":"3230_CR3","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.amjsurg.2009.06.021","volume":"200","author":"M Morrogh","year":"2010","unstructured":"Morrogh M, Park A, Elkin EB et al (2010) Lessons learned from 416 cases of nipple discharge of the breast. Am J Surg 200:73\u201380. https:\/\/doi.org\/10.1016\/j.amjsurg.2009.06.021","journal-title":"Am J Surg"},{"key":"3230_CR4","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1016\/j.amjsurg.2005.06.032","volume":"190","author":"LJ Adepoju","year":"2005","unstructured":"Adepoju LJ, Chun J, El-Tamer M et al (2005) The value of clinical characteristics and breast-imaging studies in predicting a histopathologic diagnosis of cancer or high-risk lesion in patients with spontaneous nipple discharge. Am J Surg 190:644\u2013646. https:\/\/doi.org\/10.1016\/j.amjsurg.2005.06.032","journal-title":"Am J Surg"},{"key":"3230_CR5","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1177\/000313480607200205","volume":"72","author":"HI Vargas","year":"2006","unstructured":"Vargas HI, Vargas MP, Eldrageely K et al (2006) Outcomes of clinical and surgical assessment of women with pathological nipple discharge. Am Surg 72:124\u2013128","journal-title":"Am Surg"},{"key":"3230_CR6","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1007\/s11547-007-0146-4","volume":"112","author":"L Ballesio","year":"2007","unstructured":"Ballesio L, Maggi C, Savelli S et al (2007) Adjunctive diagnostic value of ultrasonography evaluation in patients with suspected ductal breast disease. Radiol Med 112:354\u2013365. https:\/\/doi.org\/10.1007\/s11547-007-0146-4","journal-title":"Radiol Med"},{"key":"3230_CR7","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1002\/dc.1098","volume":"25","author":"DK Das","year":"2001","unstructured":"Das DK, Al-Ayadhy B, Ajrawi MT et al (2001) Cytodiagnosis of nipple discharge: a study of 602 samples from 484 cases. Diagn Cytopathol 25:25\u201337. https:\/\/doi.org\/10.1002\/dc.1098","journal-title":"Diagn Cytopathol"},{"key":"3230_CR8","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/j.diii.2015.07.004","volume":"96","author":"N Lippa","year":"2015","unstructured":"Lippa N, Hurtevent-Labrot G, Ferron S et al (2015) Nipple discharge: the role of imaging. Diagn Interv Imaging 96:1017\u20131032. https:\/\/doi.org\/10.1016\/j.diii.2015.07.004","journal-title":"Diagn Interv Imaging"},{"key":"3230_CR9","doi-asserted-by":"publisher","first-page":"465","DOI":"10.2214\/AJR.16.16682","volume":"209","author":"N Berger","year":"2017","unstructured":"Berger N, Luparia A, Di Leo G et al (2017) Diagnostic performance of MRI versus galactography in women with pathologic nipple discharge: a systematic review and meta-analysis. AJR Am J Roentgenol 209:465\u2013471. https:\/\/doi.org\/10.2214\/AJR.16.16682","journal-title":"AJR Am J Roentgenol"},{"key":"3230_CR10","doi-asserted-by":"publisher","first-page":"7783","DOI":"10.1007\/s00330-021-07790-4","volume":"31","author":"M Boisserie-Lacroix","year":"2021","unstructured":"Boisserie-Lacroix M, Doutriaux-Dumoulin I, Chopier J et al (2021) Diagnostic accuracy of breast MRI for patients with suspicious nipple discharge and negative mammography and ultrasound: a prospective study. Eur Radiol 31:7783\u20137791. https:\/\/doi.org\/10.1007\/s00330-021-07790-4","journal-title":"Eur Radiol"},{"key":"3230_CR11","doi-asserted-by":"publisher","first-page":"3187","DOI":"10.1245\/s10434-011-1962-2","volume":"18","author":"CS Fisher","year":"2011","unstructured":"Fisher CS, Margenthaler JA (2011) A look into the ductoscope: its role in pathologic nipple discharge. Ann Surg Oncol 18:3187\u20133191. https:\/\/doi.org\/10.1245\/s10434-011-1962-2","journal-title":"Ann Surg Oncol"},{"key":"3230_CR12","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1007\/s10549-019-05321-w","volume":"178","author":"K Zacharioudakis","year":"2019","unstructured":"Zacharioudakis K, Kontoulis T, Vella JX et al (2019) Can we see what is invisible? The role of MRI in the evaluation and management of patients with pathological nipple discharge. Breast Cancer Res Treat 178:115\u2013120. https:\/\/doi.org\/10.1007\/s10549-019-05321-w","journal-title":"Breast Cancer Res Treat"},{"key":"3230_CR13","doi-asserted-by":"publisher","first-page":"1639","DOI":"10.1002\/bjs.9950","volume":"102","author":"L Waaijer","year":"2015","unstructured":"Waaijer L, van Diest PJ, Verkooijen HM et al (2015) Interventional ductoscopy in patients with pathological nipple discharge. Br J Surg 102:1639\u20131648. https:\/\/doi.org\/10.1002\/bjs.9950","journal-title":"Br J Surg"},{"key":"3230_CR14","doi-asserted-by":"publisher","first-page":"e334","DOI":"10.1016\/j.clbc.2019.12.008","volume":"20","author":"MD Filipe","year":"2020","unstructured":"Filipe MD, Waaijer L, van der Pol C et al (2020) Interventional ductoscopy as an alternative for major duct excision or microdochectomy in women suffering pathologic nipple discharge: a single-center experience. Clin Breast Cancer 20:e334\u2013e343. https:\/\/doi.org\/10.1016\/j.clbc.2019.12.008","journal-title":"Clin Breast Cancer"},{"key":"3230_CR15","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s10549-021-06094-x","volume":"186","author":"MD Filipe","year":"2021","unstructured":"Filipe MD, Patuleia SIS, Vriens MR et al (2021) Meta-analysis and cost-effectiveness of ductoscopy, duct excision surgery and MRI for the diagnosis and treatment of patients with pathological nipple discharge. Breast Cancer Res Treat 186:285\u2013293. https:\/\/doi.org\/10.1007\/s10549-021-06094-x","journal-title":"Breast Cancer Res Treat"},{"issue":"Suppl 3","key":"3230_CR16","doi-asserted-by":"publisher","first-page":"S435","DOI":"10.1245\/s10434-015-4792-9","volume":"22","author":"M Bahl","year":"2015","unstructured":"Bahl M, Baker JA, Greenup RA et al (2015) Evaluation of pathologic nipple discharge: what is the added diagnostic value of MRI? Ann Surg Oncol 22(Suppl 3):S435-441. https:\/\/doi.org\/10.1245\/s10434-015-4792-9","journal-title":"Ann Surg Oncol"},{"key":"3230_CR17","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1007\/s00330-014-3521-2","volume":"25","author":"N Lubina","year":"2015","unstructured":"Lubina N, Schedelbeck U, Roth A et al (2015) 3.0 Tesla breast magnetic resonance imaging in patients with nipple discharge when mammography and ultrasound fail. Eur Radiol 25:1285\u20131293. https:\/\/doi.org\/10.1007\/s00330-014-3521-2","journal-title":"Eur Radiol"},{"key":"3230_CR18","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s11547-008-0245-x","volume":"113","author":"L Ballesio","year":"2008","unstructured":"Ballesio L, Maggi C, Savelli S et al (2008) Role of breast magnetic resonance imaging (MRI) in patients with unilateral nipple discharge: preliminary study. Radiol Med 113:249\u2013264. https:\/\/doi.org\/10.1007\/s11547-008-0245-x","journal-title":"Radiol Med"}],"container-title":["Irish Journal of Medical Science (1971 -)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-022-03230-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11845-022-03230-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-022-03230-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T01:06:12Z","timestamp":1695776772000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11845-022-03230-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,21]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["3230"],"URL":"https:\/\/doi.org\/10.1007\/s11845-022-03230-4","relation":{},"ISSN":["0021-1265","1863-4362"],"issn-type":[{"value":"0021-1265","type":"print"},{"value":"1863-4362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,21]]},"assertion":[{"value":"3 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 November 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This retrospective study was approved by the institutional review board, and the requirement of written informed consent was waived.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}