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Men were randomly assigned to the lifestyle modification group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200930, received low-calorie diet and moderate-intensity treadmill walking programs) or waitlist group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200930). The following outcomes were assessed as follows: body mass index, psoriasis severity (assessed via psoriasis area and severity index), ED (assessed by the five-item internal index of erectile function), and components of MeTS (waist circumference, blood pressure, serum high-density lipoprotein, serum triglycerides, and serum fasting blood glucose).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Trends of significant improvements in all outcomes were documented in favor of the lifestyle modification group. All outcomes of the waitlist group did not show the same reported significant improvements of the lifestyle modification group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A 12-week lifestyle modification program as a tool for weight loss in obese men with CPP is a good therapeutic method to improve psoriasis severity and psoriasis-associated ED and MeTS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11845-023-03412-8","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T14:06:29Z","timestamp":1685541989000},"page":"523-529","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Erectile dysfunction and metabolic syndrome components in obese men with psoriasis: response to a 12-week randomized controlled lifestyle modification program (exercise with diet restriction)"],"prefix":"10.1007","volume":"193","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1447-8817","authenticated-orcid":false,"given":"Ali Mohamed Ali","family":"Ismail","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina E.","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"issue":"4","key":"3412_CR1","first-page":"581","volume":"18","author":"T Tasliyurt","year":"2014","unstructured":"Tasliyurt T, Bilir Y, Sahin S et al (2014) Erectile dysfunction in patients with psoriasis: potential impact of the metabolic syndrome. 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This single-blinded lifestyle-modification approach in CPP men with MeTS and ED received local institutional approval (P.T.REC\/012\/004117).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All CPP men with MeTS and ED consented.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"This is not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}}]}}