{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:57:00Z","timestamp":1780617420120,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T00:00:00Z","timestamp":1695081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T00:00:00Z","timestamp":1695081600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100014993","name":"the Foundation of Healthcare Project of Military Logistics","doi-asserted-by":"publisher","award":["17BJZ46"],"award-info":[{"award-number":["17BJZ46"]}],"id":[{"id":"10.13039\/501100014993","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009580","name":"General Hospital of People\u2019s Liberation Army","doi-asserted-by":"publisher","award":["2017FC-TSYS-2020"],"award-info":[{"award-number":["2017FC-TSYS-2020"]}],"id":[{"id":"10.13039\/501100009580","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017964","name":"Tianjin Municipal Health Commission","doi-asserted-by":"publisher","award":["TJWJ2023MS069"],"award-info":[{"award-number":["TJWJ2023MS069"]}],"id":[{"id":"10.13039\/100017964","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ir J Med Sci"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s11845-023-03527-y","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T06:02:13Z","timestamp":1695103333000},"page":"699-703","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparison of jejunal aspirate culture and methane and hydrogen breath test in the diagnosis of small intestinal bacterial overgrowth"],"prefix":"10.1007","volume":"193","author":[{"given":"Shuai","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,9,19]]},"reference":[{"key":"3527_CR1","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1053\/j.gastro.2022.04.002","volume":"163","author":"D Bushyhead","year":"2022","unstructured":"Bushyhead D, Quigley EMM (2022) Small intestinal bacterial overgrowth\u2014pathophysiology and its implications for definition and management. Gastroenterology 163:593\u2013607. https:\/\/doi.org\/10.1053\/j.gastro.2022.04.002","journal-title":"Gastroenterology"},{"key":"3527_CR2","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1111\/jgh.15892","volume":"37","author":"X Sun","year":"2022","unstructured":"Sun X, Wang F, Liu J et al (2022) Risk factors for small-intestinal mucosal breaks beyond aspirin. J Gastroenterol Hepatol 37:1596\u20131602. https:\/\/doi.org\/10.1111\/jgh.15892","journal-title":"J Gastroenterol Hepatol"},{"key":"3527_CR3","doi-asserted-by":"publisher","first-page":"2978","DOI":"10.3748\/wjg.v16.i24.2978","volume":"16","author":"J Bures","year":"2010","unstructured":"Bures J, Cyrany J, Kohoutova D et al (2010) Small intestinal bacterial overgrowth syndrome. World J Gastroenterol 16:2978\u20132990. https:\/\/doi.org\/10.3748\/wjg.v16.i24.2978","journal-title":"World J Gastroenterol"},{"key":"3527_CR4","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1007\/s10620-007-0065-1","volume":"53","author":"R Khoshini","year":"2008","unstructured":"Khoshini R, Dai SC, Lezcano S et al (2008) A systematic review of diagnostic tests for small intestinal bacterial overgrowth. Dig Dis Sci 53:1443\u20131454. https:\/\/doi.org\/10.1007\/s10620-007-0065-1","journal-title":"Dig Dis Sci"},{"key":"3527_CR5","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1111\/apt.12456","volume":"38","author":"E Grace","year":"2013","unstructured":"Grace E, Shaw C, Whelan K et al (2013) Review article: small intestinal bacterial overgrowth\u2013prevalence, clinical features, current and developing diagnostic tests, and treatment. Aliment Pharmacol Ther 38:674\u2013688. https:\/\/doi.org\/10.1111\/apt.12456","journal-title":"Aliment Pharmacol Ther"},{"issue":"Suppl 1","key":"3527_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-2036.2009.03951.x","volume":"29","author":"A Gasbarrini","year":"2009","unstructured":"Gasbarrini A, Corazza GR, Gasbarrini G et al (2009) Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference. Aliment Pharmacol Ther 29(Suppl 1):1\u201349. https:\/\/doi.org\/10.1111\/j.1365-2036.2009.03951.x","journal-title":"Aliment Pharmacol Ther"},{"key":"3527_CR7","first-page":"6","volume":"25","author":"UC Ghoshal","year":"2006","unstructured":"Ghoshal UC, Ghoshal U, Das K et al (2006) Utility of hydrogen breath tests in diagnosis of small intestinal bacterial overgrowth in malabsorption syndrome and its relationship with oro-cecal transit time. Indian J Gastroenterol 25:6\u201310","journal-title":"Indian J Gastroenterol"},{"key":"3527_CR8","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1038\/ajg.2017.46","volume":"112","author":"A Rezaie","year":"2017","unstructured":"Rezaie A, Buresi M, Lembo A et al (2017) Hydrogen and methane-based breath testing in gastrointestinal disorders: the North American Consensus. Am J Gastroenterol 112:775\u2013784. https:\/\/doi.org\/10.1038\/ajg.2017.46","journal-title":"Am J Gastroenterol"},{"key":"3527_CR9","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1080\/17474124.2023.2207008","volume":"17","author":"UC Ghoshal","year":"2023","unstructured":"Ghoshal UC, Ghoshal U, Shah A et al (2023) Evaluation of small intestinal bacterial overgrowth. Expert Rev Gastroenterol Hepatol 17:461\u2013467. https:\/\/doi.org\/10.1080\/17474124.2023.2207008","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"3527_CR10","doi-asserted-by":"publisher","first-page":"16","DOI":"10.5056\/jnm19113","volume":"26","author":"G Losurdo","year":"2020","unstructured":"Losurdo G, Leandro G, Ierardi E et al (2020) Breath tests for the non-invasive diagnosis of small intestinal bacterial overgrowth: a systematic review with meta-analysis. J Neurogastroenterol Motil 26:16\u201328. https:\/\/doi.org\/10.5056\/jnm19113","journal-title":"J Neurogastroenterol Motil"},{"key":"3527_CR11","doi-asserted-by":"publisher","first-page":"165","DOI":"10.14309\/ajg.0000000000000501","volume":"115","author":"M Pimentel","year":"2020","unstructured":"Pimentel M, Saad RJ, Long MD et al (2020) ACG clinical guideline: small intestinal bacterial overgrowth. Am J Gastroenterol 115:165\u2013178. https:\/\/doi.org\/10.14309\/ajg.0000000000000501","journal-title":"Am J Gastroenterol"},{"key":"3527_CR12","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1111\/nmo.12516","volume":"27","author":"A Erdogan","year":"2015","unstructured":"Erdogan A, Rao SS, Gulley D et al (2015) Small intestinal bacterial overgrowth: duodenal aspiration vs glucose breath test. Neurogastroenterol Motil 27:481\u2013489. https:\/\/doi.org\/10.1111\/nmo.12516","journal-title":"Neurogastroenterol Motil"},{"key":"3527_CR13","doi-asserted-by":"publisher","first-page":"253","DOI":"10.3109\/00365529208999959","volume":"27","author":"PK Bardhan","year":"1992","unstructured":"Bardhan PK, Gyr K, Beglinger C et al (1992) Diagnosis of bacterial overgrowth after culturing proximal small-bowel aspirate obtained during routine upper gastrointestinal endoscopy. Scand J Gastroenterol 27:253\u2013256. https:\/\/doi.org\/10.3109\/00365529208999959","journal-title":"Scand J Gastroenterol"},{"key":"3527_CR14","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1136\/gut.2006.108712","volume":"56","author":"I Posserud","year":"2007","unstructured":"Posserud I, Stotzer PO, Bjornsson ES et al (2007) Small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Gut 56:802\u2013808. https:\/\/doi.org\/10.1136\/gut.2006.108712","journal-title":"Gut"},{"key":"3527_CR15","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/ueg2.12133","volume":"10","author":"HF Hammer","year":"2022","unstructured":"Hammer HF, Fox MR, Keller J et al (2022) European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus. United European Gastroenterol J 10:15\u201340. https:\/\/doi.org\/10.1002\/ueg2.12133","journal-title":"United European Gastroenterol J"},{"key":"3527_CR16","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1111\/j.1365-2036.2005.02690.x","volume":"22","author":"A Lupascu","year":"2005","unstructured":"Lupascu A, Gabrielli M, Lauritano EC et al (2005) Hydrogen glucose breath test to detect small intestinal bacterial overgrowth: a prevalence case-control study in irritable bowel syndrome. Aliment Pharmacol Ther 22:1157\u20131160. https:\/\/doi.org\/10.1111\/j.1365-2036.2005.02690.x","journal-title":"Aliment Pharmacol Ther"},{"key":"3527_CR17","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1159\/000336174","volume":"85","author":"SV Rana","year":"2012","unstructured":"Rana SV, Sharma S, Kaur J et al (2012) Comparison of lactulose and glucose breath test for diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Digestion 85:243\u2013247. https:\/\/doi.org\/10.1159\/000336174","journal-title":"Digestion"},{"key":"3527_CR18","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1111\/j.1572-0241.2003.07234.x","volume":"98","author":"M Pimentel","year":"2003","unstructured":"Pimentel M, Chow EJ, Lin HC (2003) Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome. a double-blind, randomized, placebo-controlled study. Am J Gastroenterol 98:412\u2013419. https:\/\/doi.org\/10.1111\/j.1572-0241.2003.07234.x","journal-title":"Am J Gastroenterol"},{"key":"3527_CR19","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/0016-5085(90)90818-l","volume":"98","author":"GR Corazza","year":"1990","unstructured":"Corazza GR, Menozzi MG, Strocchi A et al (1990) The diagnosis of small bowel bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing. Gastroenterology 98:302\u2013309. https:\/\/doi.org\/10.1016\/0016-5085(90)90818-l","journal-title":"Gastroenterology"},{"key":"3527_CR20","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1001\/jama.292.7.852","volume":"292","author":"HC Lin","year":"2004","unstructured":"Lin HC (2004) Small intestinal bacterial overgrowth: a framework for understanding irritable bowel syndrome. JAMA 292:852\u2013858. https:\/\/doi.org\/10.1001\/jama.292.7.852","journal-title":"JAMA"}],"container-title":["Irish Journal of Medical Science (1971 -)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-023-03527-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11845-023-03527-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-023-03527-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T04:01:05Z","timestamp":1711339265000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11845-023-03527-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,19]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["3527"],"URL":"https:\/\/doi.org\/10.1007\/s11845-023-03527-y","relation":{},"ISSN":["0021-1265","1863-4362"],"issn-type":[{"value":"0021-1265","type":"print"},{"value":"1863-4362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,19]]},"assertion":[{"value":"20 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the Ethics Committee of Chinese PLA General Hospital (S2018-081-02) and with the 1964 Helsinki declaration and its subsequent amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare that they have no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}