{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T11:08:46Z","timestamp":1779275326881,"version":"3.51.4"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ir J Med Sci"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s11845-025-04186-x","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:21:55Z","timestamp":1766398915000},"page":"917-923","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anal intraepithelial neoplasia in Ireland: practice patterns and the case for regionalisation"],"prefix":"10.1007","volume":"195","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7051-1688","authenticated-orcid":false,"given":"Lucy","family":"Burns","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Keane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Loughlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"issue":"2","key":"4186_CR1","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.ejso.2020.08.011","volume":"47","author":"K Knight","year":"2021","unstructured":"Knight K, Al-Wahid M, Choong JX, Burton K, Lindsay R, McKee RF et al (2021) Multidisciplinary management of anal intraepithelial neoplasia and rate of progression to cancer: a retrospective cohort study. Eur J Surg Oncol 47(2):304\u201310","journal-title":"Eur J Surg Oncol"},{"issue":"6","key":"4186_CR2","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1007\/s13304-021-01156-7","volume":"73","author":"DRL Brogden","year":"2021","unstructured":"Brogden DRL, Lupi MEE, Warren OJ, Kontovounisios C, Mills SC (2021) Comparing and contrasting clinical consensus and guidelines for anal intraepithelial neoplasia in different geographical regions. Update Surg 73(6):2047\u20132058","journal-title":"Update Surg"},{"issue":"6","key":"4186_CR3","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s10151-019-02019-5","volume":"23","author":"GA Binda","year":"2019","unstructured":"Binda GA, Gagliardi G, Dal Conte I, Verra M, Cassoni P, Cavazzoni E et al (2019) Practice parameters for the diagnosis and treatment of anal intraepithelial neoplasia (AIN) on behalf of the Italian society of colorectal surgery (SICCR). Tech Coloproctol 23(6):513\u2013528","journal-title":"Tech Coloproctol"},{"issue":"7","key":"4186_CR4","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1097\/DCR.0000000000001114","volume":"61","author":"DB Stewart","year":"2018","unstructured":"Stewart DB, Gaertner WB, Glasgow SC, Herzig DO, Feingold D, Steele SR (2018) The American society of colon and rectal surgeons clinical practice guidelines for anal squamous cell cancers (Revised 2018). Dis Colon Rectum 61(7):755\u2013774","journal-title":"Dis Colon Rectum"},{"issue":"9","key":"4186_CR5","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.annonc.2021.06.015","volume":"32","author":"S Rao","year":"2021","unstructured":"Rao S, Guren MG, Khan K, Brown G, Renehan AG, Steigen SE et al (2021) Anal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up(\u2606). Ann Oncol 32(9):1087\u2013100","journal-title":"Ann Oncol"},{"issue":"24","key":"4186_CR6","doi-asserted-by":"publisher","first-page":"2273","DOI":"10.1056\/NEJMoa2201048","volume":"386","author":"JM Palefsky","year":"2022","unstructured":"Palefsky JM, Lee JY, Jay N, Goldstone SE, Darragh TM, Dunlevy HA et al (2022) Treatment of anal high-grade squamous intraepithelial lesions to prevent anal cancer. N Engl J Med 386(24):2273\u20132282","journal-title":"N Engl J Med"},{"issue":"1","key":"4186_CR7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.21873\/anticanres.13075","volume":"39","author":"A Gudur","year":"2019","unstructured":"Gudur A, Shanmuganandamurthy D, Szep Z, Poggio JL (2019) An update on the current role of high resolution anoscopy in patients with anal dysplasia. Anticancer Res 39(1):17\u201323","journal-title":"Anticancer Res"},{"issue":"Suppl 1","key":"4186_CR8","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1111\/codi.13709","volume":"19","author":"I Geh","year":"2017","unstructured":"Geh I, Gollins S, Renehan A, Scholefield J, Goh V, Prezzi D et al (2017) Association of coloproctology of great Britain & Ireland (ACPGBI): guidelines for the management of cancer of the Colon, rectum and anus (2017) - Anal cancer. Colorectal Dis 19(Suppl 1):82\u201397","journal-title":"Colorectal Dis"},{"key":"4186_CR9","doi-asserted-by":"crossref","unstructured":"Espirito Santo I, Kefleyesus A, Chilou C, Faes S, Clerc D, H\u00fcbner M et al (2025) Anal cancer screening: 10-Year experience of a specialized outpatient clinic. Cancers (Basel) 17(2)","DOI":"10.3390\/cancers17020193"},{"issue":"8","key":"4186_CR10","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s11894-018-0640-y","volume":"20","author":"P Rider","year":"2018","unstructured":"Rider P, Hunter J, Grimm L (2018) The diagnostic and therapeutic challenge of anal intraepithelial neoplasia. Curr Gastroenterol Rep 20(8):38","journal-title":"Curr Gastroenterol Rep"},{"issue":"10","key":"4186_CR11","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.5858\/arpa.LGT200570","volume":"136","author":"TM Darragh","year":"2012","unstructured":"Darragh TM, Colgan TJ, Cox JT, Heller DS, Henry MR, Luff RD et al (2012) The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Arch Pathol Lab Med 136(10):1266\u201397","journal-title":"Arch Pathol Lab Med"},{"issue":"10","key":"4186_CR12","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.1007\/s00384-020-03640-9","volume":"35","author":"M Power Foley","year":"2020","unstructured":"Power Foley M, Kelly ME, Kerr C, Kennedy C, Gallagher D, Gillham C et al (2020) Management of anal intraepithelial neoplasia and anal squamous cell carcinoma at a tertiary referral centre with a dedicated infectious diseases unit: an 18-year review. Int J Colorectal Dis 35(10):1855\u20131864","journal-title":"Int J Colorectal Dis"},{"key":"4186_CR13","unstructured":"Ireland NCR Cancer Trends (2024) 40 \u2013 HPV Associated Cancers Cork2024 Available from: https:\/\/www.ncri.ie\/en\/reports-publications\/reports\/cancer-trends-40-hpv-associated-cancers"},{"issue":"2","key":"4186_CR14","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1002\/cncr.30327","volume":"123","author":"A Amini","year":"2017","unstructured":"Amini A, Jones BL, Ghosh D, Schefter TE, Goodman KA (2017) Impact of facility volume on outcomes in patients with squamous cell carcinoma of the anal canal: analysis of the National cancer data base. Cancer 123(2):228\u2013236","journal-title":"Cancer"},{"key":"4186_CR15","doi-asserted-by":"publisher","first-page":"651","DOI":"10.2147\/OTT.S38217","volume":"6","author":"SE Weis","year":"2013","unstructured":"Weis SE (2013) Current treatment options for management of anal intraepithelial neoplasia. Onco Targets Ther 6:651\u2013665","journal-title":"Onco Targets Ther"},{"issue":"13","key":"4186_CR16","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.4253\/wjge.v7.i13.1083","volume":"7","author":"A Albuquerque","year":"2015","unstructured":"Albuquerque A (2015) High-resolution anoscopy: unchartered territory for gastroenterologists? World J Gastrointest Endosc 7(13):1083\u20131087","journal-title":"World J Gastrointest Endosc"},{"issue":"10","key":"4186_CR17","doi-asserted-by":"publisher","first-page":"1694","DOI":"10.1002\/ijc.34850","volume":"154","author":"EA Stier","year":"2024","unstructured":"Stier EA, Clarke MA, Deshmukh AA et al (2024) International Anal Neoplasia Society\u2019s consensus guidelines for anal cancer screening. Int J Cancer 154(10):1694\u20131702. https:\/\/doi.org\/10.1002\/ijc.34850","journal-title":"Int J Cancer"}],"container-title":["Irish Journal of Medical Science (1971 -)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-025-04186-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11845-025-04186-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11845-025-04186-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T10:40:47Z","timestamp":1779273647000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11845-025-04186-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,22]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["4186"],"URL":"https:\/\/doi.org\/10.1007\/s11845-025-04186-x","relation":{},"ISSN":["0021-1265","1863-4362"],"issn-type":[{"value":"0021-1265","type":"print"},{"value":"1863-4362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,22]]},"assertion":[{"value":"30 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors of this article declare no conflicts of interest with the work presented in the article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}