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This study evaluated demographic, clinical, and postmortem characteristics of patients with schizophrenia, with particular focus on antipsychotic use, death circumstances, and organ pathology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on 107 autopsy cases from 2020 to 2024. Data on demographics, clinical history, toxicology, and macroscopic organ findings were collected and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most patients were male (70.1%) with a mean age of 50\u2009\u00b1\u200913.8 years. Natural deaths accounted for 56.1%, predominantly cardiovascular, whereas non-natural deaths comprised 43.9%, mainly trauma and asphyxia. Antipsychotics were detected in 61.3% of cases, often in combination, and antidepressants in 21.7%. Combined antipsychotic use was associated with a lower likelihood of being found dead.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Deaths in schizophrenia are influenced by cardiovascular, traumatic, metabolic, and pharmacological factors. Postmortem evaluations indicate limited macroscopic effects of psychotropic medications. Mortality risk assessment should integrate clinical, pharmacological, and sociodemographic factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11845-025-04274-y","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T03:33:19Z","timestamp":1768793599000},"page":"295-302","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The end of fragmented consciousness: deaths in schizophrenia\u2014an autopsy-based study"],"prefix":"10.1007","volume":"195","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1262-6452","authenticated-orcid":false,"given":"Filiz Ekim","family":"\u00c7evi\u0307k","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5640-8329","authenticated-orcid":false,"given":"Ayt\u00fcl","family":"Bu\u011fra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5831-6583","authenticated-orcid":false,"given":"Muhammed","family":"Oduncu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2491-6270","authenticated-orcid":false,"given":"Yasin","family":"Kavla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcseyin \u00c7a\u011fr\u0131","family":"\u015eahi\u0307n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0352-8677","authenticated-orcid":false,"given":"Muhammed Fatih","family":"Yaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1247-7242","authenticated-orcid":false,"given":"Furkan","family":"Do\u011fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6860-5723","authenticated-orcid":false,"given":"Hatice B\u00fc\u015fra","family":"Arisin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7800-8657","authenticated-orcid":false,"given":"\u0130brahim","family":"\u00dcz\u00fcn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6845-3717","authenticated-orcid":false,"given":"H\u0131z\u0131r","family":"Asliy\u00fcksek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"issue":"2","key":"4274_CR1","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1002\/wps.20994","volume":"21","author":"CU Correll","year":"2022","unstructured":"Correll CU, Solmi M, Croatto G et al (2022) Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. 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As this was a retrospective study based on medicolegal autopsy reports and related documentation, individual informed consent was not applicable. All data were anonymized before extraction and analysis, and no identifiable personal information was used. Confidentiality was strictly maintained in accordance with institutional regulations, national legal requirements, and the principles of the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}