{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:47:20Z","timestamp":1759333640587},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr. Treat. Options in Oncol."],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1007\/s11864-004-0016-4","type":"journal-article","created":{"date-parts":[[2007,6,28]],"date-time":"2007-06-28T08:39:28Z","timestamp":1183019968000},"page":"249-257","source":"Crossref","is-referenced-by-count":39,"title":["Treatment of poems syndrome"],"prefix":"10.1007","volume":"5","author":[{"given":"Angela","family":"Dispenzieri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morie A.","family":"Gertz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"16_CR1","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1097\/00005792-198007000-00006","volume":"59","author":"PA Bardwick","year":"1980","unstructured":"Bardwick PA, Zvaifler NJ, Gill GN, et al.: Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature. Medicine 1980, 59:311\u2013322. Authors introduce two new cases and review the literature, but devise the acronym POEMS to refer to the syndrome.","journal-title":"Medicine"},{"key":"16_CR2","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1212\/WNL.34.6.712","volume":"34","author":"T Nakanishi","year":"1984","unstructured":"Nakanishi T, Sobue I, Toyokura Y, et al.: The Crow-Fukase syndrome: a study of 102 cases in Japan. Neurology 1984, 34:712\u2013720. The largest English language report of the syndrome from Japan (102 patients from a nationwide survey and review of the Japanese literature). The paper emphasizes that the syndrome may exist in the absence of bone lesions, may be associated with Castleman disease, and monoclonal kappa plasma cell clones are rare.","journal-title":"Neurology"},{"key":"16_CR3","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1097\/00005792-198007000-00005","volume":"59","author":"H Driedger","year":"1980","unstructured":"Driedger H, Pruzanski W: Plasma cell neoplasia with peripheral polyneuropathy. A study of five cases and a review of the literature. Medicine 1980, 59:301\u2013310.","journal-title":"Medicine"},{"key":"16_CR4","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/0002-9343(94)90350-6","volume":"97","author":"MJ Soubrier","year":"1994","unstructured":"Soubrier MJ, Dubost JJ, Sauvezie BJ: POEMS syndrome: a study of 25 cases and a review of the literature. French Study Group on POEMS Syndrome. Am J Med 1994, 97:543\u2013553. A report of 25 patients from France with an extensive review of the literature incorporating 114 non-Asian cases derived from 76 reports, in addition to the 102 cases in Japan reported by Nakanishi et al. [2\u2022].","journal-title":"Am J Med"},{"key":"16_CR5","doi-asserted-by":"publisher","first-page":"2496","DOI":"10.1182\/blood-2002-07-2299","volume":"101","author":"A Dispenzieri","year":"2003","unstructured":"Dispenzieri A, Kyle RA, Lacy MQ, et al.: POEMS syndrome: definitions and long-term outcome. Blood 2003, 101:2496\u20132506. This paper involves the largest series (99 patients) from a single institution. It sets forth diagnostic criteria for the diagnosis. The paper emphasizes that the long-term outcome for patients is good, the number of POEMS features is not prognostic, patients can acquire additional features over time, and pulmonary hypertension and congestive heart failure may be part of the syndrome. The authors demonstrate that fingernail clubbing and extravascular volume overload are the presenting features most predictive of survival.","journal-title":"Blood"},{"key":"16_CR6","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1002\/1097-4598(200007)23:7<1051::AID-MUS7>3.0.CO;2-V","volume":"23","author":"T Hashiguchi","year":"2000","unstructured":"Hashiguchi T, Arimura K, Matsumuro K, et al.: Highly concentrated vascular endothelial growth factor in platelets in Crow-Fukase syndrome. Muscle Nerve 2000, 23:1051\u20131056.","journal-title":"Muscle Nerve"},{"key":"16_CR7","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1002\/(SICI)1097-4598(199811)21:11<1390::AID-MUS5>3.0.CO;2-4","volume":"21","author":"O Watanabe","year":"1998","unstructured":"Watanabe O, Maruyama I, Arimura K, et al.: Overproduction of vascular endothelial growth factor\/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome. Muscle Nerve 1998, 21:1390\u20131397. Authors make a convincing case that the overproduction of VEGF\/vascular permeability factor is important in the pathogenesis of this disorder. They examined the levels of the VEGF in the serum and cerebrospinal fluid from 10 patients with this syndrome and demonstrated that serum VEGF levels were approximately 15 to 30 times greater than serum levels in controls.","journal-title":"Muscle Nerve"},{"key":"16_CR8","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1136\/jnnp.30.5.432","volume":"30","author":"JB Morley","year":"1967","unstructured":"Morley JB, Schwieger AC: The relation between chronic polyneuropathy and osteosclerotic myeloma. J Neurol Neurosurg Psychiatry 1967, 30:432\u2013442.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"16_CR9","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1001\/archneur.1972.00490180043010","volume":"27","author":"L Davis","year":"1972","unstructured":"Davis L, Drachman D: Myeloma neuropathy. Successful treatment of two patients and review of cases. Arch Neurol 1972, 27:507\u2013511.","journal-title":"Arch Neurol"},{"key":"16_CR10","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1212\/WNL.27.7.675","volume":"27","author":"H Iwashita","year":"1977","unstructured":"Iwashita H, Ohnishi A, Asada M, et al.: Polyneuropathy, skin hyperpigmentation, edema, and hypertrichosis in localized osteosclerotic myeloma. Neurology 1977, 27:675\u2013681. One of the early articles defining the paraneoplastic syndrome referred to as POEMS.","journal-title":"Neurology"},{"key":"16_CR11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.bbmt.2003.12.049","volume":"10","author":"A Dispenzieri","year":"2004","unstructured":"Dispenzieri A, Moreno-Aspitia A, Lacy MQ, et al.: Peripheral blood stem cell transplant (PBSCT) in a large series of patients with POEMS syndrome. Biol Blood Marrow Transplant 2004, 10:14\u201315.","journal-title":"Biol Blood Marrow Transplant"},{"key":"16_CR12","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/sj.bmt.1703108","volume":"28","author":"WJ Hogan","year":"2001","unstructured":"Hogan WJ, Lacy MQ, Wiseman GA, et al.: Successful treatment of POEMS syndrome with autologous hematopoietic progenitor cell transplantation. Bone Marrow Transplant 2001, 28:305\u2013309. First report of a successful peripheral blood stem cell transplant in a patient with POEMS.","journal-title":"Bone Marrow Transplant"},{"key":"16_CR13","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1046\/j.1365-2141.2001.03040.x","volume":"115","author":"M Rovira","year":"2001","unstructured":"Rovira M, Carreras E, Blade J, et al.: Dramatic improvement of POEMS syndrome following autologous haematopoietic cell transplantation. Br J Haematol 2001, 115:373\u2013375.","journal-title":"Br J Haematol"},{"key":"16_CR14","doi-asserted-by":"publisher","first-page":"3057","DOI":"10.1182\/blood.V99.8.3057","volume":"99","author":"A Jaccard","year":"2002","unstructured":"Jaccard A, Royer B, Bordessoule D, et al.: High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome. Blood 2002, 99:3057\u20133059. Largest published series of patients with POEMS who were treated with peripheral blood stem cell transplant.","journal-title":"Blood"},{"key":"16_CR15","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1038\/sj.bmt.1703670","volume":"30","author":"KS Peggs","year":"2002","unstructured":"Peggs KS, Paneesha S, Kottaridis PD, et al.: Peripheral blood stem cell transplantation for POEMS syndrome. Bone Marrow Transplant 2002, 30:401\u2013404.","journal-title":"Bone Marrow Transplant"},{"key":"16_CR16","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/sj.bmt.1703600","volume":"30","author":"M Soubrier","year":"2002","unstructured":"Soubrier M, Ruivard M, Dubost JJ, et al.: Successful use of autologous bone marrow transplantation in treating a patient with POEMS syndrome. Bone Marrow Transplant 2002, 30:61\u201362.","journal-title":"Bone Marrow Transplant"},{"key":"16_CR17","doi-asserted-by":"publisher","first-page":"2679","DOI":"10.1182\/blood-2002-07-2030","volume":"100","author":"A Wiesmann","year":"2002","unstructured":"Wiesmann A, Weissert R, Kanz L, Einsele H: Long-term follow-up on a patient with incomplete POEMS syndrome undergoing high-dose therapy and autologous blood stem cell transplantation. Blood 2002, 100:2679\u20132680.","journal-title":"Blood"},{"key":"16_CR18","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1136\/jnnp.52.2.286","volume":"52","author":"JH Barrier","year":"1989","unstructured":"Barrier JH, Le Noan H, Mussini JM, Brisseau JM: Stabilisation of a severe case of P.O.E.M.S. syndrome after tamoxifen administration [letter]. J Neurol Neurosurg Psychiatry 1989, 52:286.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"16_CR19","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/jnnp.55.1.71","volume":"55","author":"TP Enevoldson","year":"1992","unstructured":"Enevoldson TP, Harding AE: Improvement in the POEMS syndrome after administration of tamoxifen [letter]. J Neurol Neurosurg Psychiatry 1992, 55:71\u201372.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"16_CR20","first-page":"416","volume":"6","author":"V Coto","year":"1991","unstructured":"Coto V, Auletta M, Oliviero U, et al.: POEMS syndrome: an Italian case with diagnostic and therapeutic implications. Ann Ital Med Int 1991, 6:416\u2013419.","journal-title":"Ann Ital Med Int"},{"key":"16_CR21","first-page":"112","volume":"83","author":"F Arima","year":"1992","unstructured":"Arima F, Dohmen K, Yamano Y, et al.: [Five cases of Crow-Fukase syndrome]. Fukuoka Igaku Zasshi 1992, 83:112\u2013120.","journal-title":"Fukuoka Igaku Zasshi"},{"key":"16_CR22","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1002\/art.1780390824","volume":"39","author":"FJ Authier","year":"1996","unstructured":"Authier FJ, Belec L, Levy Y, et al.: All-trans-retinoic acid in POEMS syndrome. Therapeutic effect associated with decreased circulating levels of proinflammatory cytokines. Arthritis Rheum 1996, 39:1423\u20131426.","journal-title":"Arthritis Rheum"},{"key":"16_CR23","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1080\/01616412.1994.11740278","volume":"16","author":"G Orefice","year":"1994","unstructured":"Orefice G, Morra VB, De Michele G, et al.: POEMS syndrome: clinical, pathological, and immunological study of a case. Neurol Res 1994, 16:477\u2013480.","journal-title":"Neurol Res"},{"key":"16_CR24","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/BF00705402","volume":"409","author":"M Sano","year":"1986","unstructured":"Sano M, Terasaki T, Koyama A, et al.: Glomerular lesions associated with the Crow-Fukase syndrome. Virchows Arch A Pathol Anat Histopathol 1986, 409:3\u20139.","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"16_CR25","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1007\/BF00873555","volume":"242","author":"T Henze","year":"1995","unstructured":"Henze T, Krieger G: Combined high-dose 7S-IgG and dexamethasone is effective in severe polyneuropathy of the POEMS syndrome [letter]. J Neurol 1995, 242:482\u2013483.","journal-title":"J Neurol"},{"key":"16_CR26","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1002\/(SICI)1097-4598(199708)20:8<1035::AID-MUS16>3.0.CO;2-U","volume":"20","author":"FT Rotta","year":"1997","unstructured":"Rotta FT, Bradley WG: Marked improvement of severe polyneuropathy associated with multifocal osteosclerotic myeloma following surgery, radiation, and chemotherapy. Muscle Nerve 1997, 20:1035\u20131037.","journal-title":"Muscle Nerve"},{"key":"16_CR27","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000203980","volume":"94","author":"T Atsumi","year":"1995","unstructured":"Atsumi T, Kato K, Kurosawa S, et al.: A case of Crow-Fukase syndrome with elevated soluble interleukin-6 receptor in cerebrospinal fluid. Response to doublefiltration plasmapheresis and corticosteroids. Acta Haematol 1995, 94:90\u201394.","journal-title":"Acta Haematol"},{"key":"16_CR28","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1136\/jnnp.63.3.385","volume":"63","author":"S Kuwabara","year":"1997","unstructured":"Kuwabara S, Hattori T, Shimoe Y, Kamitsukasa I: Longterm melphalan-prednisolone chemotherapy for POEMS syndrome. J Neurol Neurosurg Psychiatry 1997, 63:385\u2013387.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"16_CR29","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1177\/003693308903400504","volume":"34","author":"PM Stewart","year":"1989","unstructured":"Stewart PM, McIntyre MA, Edwards CR: The endocrinopathy of POEMS syndrome. Scott Med J 1989, 34:520\u2013522.","journal-title":"Scott Med J"},{"key":"16_CR30","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1212\/WNL.38.4.614","volume":"38","author":"M Reulecke","year":"1988","unstructured":"Reulecke M, Dumas M, Meier C: Specific antibody activity against neuroendocrine tissue in a case of POEMS syndrome with IgG gammopathy. Neurology 1988, 38:614\u2013616.","journal-title":"Neurology"},{"key":"16_CR31","doi-asserted-by":"crossref","unstructured":"Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6633 patients from 27 randomized trials. Myeloma Trialists\u2019 Collaborative Group. J Clin Oncol 1998, 16:3832\u20133842.","DOI":"10.1200\/JCO.1998.16.12.3832"},{"key":"16_CR32","doi-asserted-by":"crossref","first-page":"660","DOI":"10.2169\/internalmedicine.35.660","volume":"35","author":"K Satoh","year":"1996","unstructured":"Satoh K, Miura I, Chubachi A, et al.: Development of secondary leukemia associated with (1;7)(q10;p10) in a patient with Crow-Fukase syndrome. Intern Med 1996, 35:660\u2013662.","journal-title":"Intern Med"},{"key":"16_CR33","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1111\/j.0954-6820.1980.tb01167.x","volume":"208","author":"JB Reitan","year":"1980","unstructured":"Reitan JB, Pape E, Fossa SD, et al.: Osteosclerotic myeloma with polyneuropathy. Acta Med Scand 1980, 208:137\u2013144.","journal-title":"Acta Med Scand"},{"key":"16_CR34","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1016\/S0003-9993(95)80643-1","volume":"76","author":"A Ku","year":"1995","unstructured":"Ku A, Lachmann E, Tunkel R, Nagler W: Severe polyneuropathy: initial manifestation of Castleman\u2019s disease associated with POEMS syndrome. Arch Phys Med Rehabil 1995, 76:692\u2013694.","journal-title":"Arch Phys Med Rehabil"},{"key":"16_CR35","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/S0140-6736(96)91260-X","volume":"347","author":"JM Cabezas-Agricola","year":"1996","unstructured":"Cabezas-Agricola JM, Lado-Abeal JJ, Otero-Anton E, et al.: Hypoparathyroidism in POEMS syndrome [letter]. Lancet 1996, 347:701\u2013702.","journal-title":"Lancet"},{"key":"16_CR36","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0303-8467(92)90122-J","volume":"94","author":"C Crisci","year":"1992","unstructured":"Crisci C, Barbieri F, Parente D, et al.: POEMS syndrome: follow-up study of a case. Clin Neurol Neurosurg 1992, 94:65\u201368.","journal-title":"Clin Neurol Neurosurg"},{"key":"16_CR37","first-page":"543","volume":"13","author":"K Takatsuki","year":"1983","unstructured":"Takatsuki K, Sanada I: Plasma cell dyscrasia with polyneuropathy and endocrine disorder: clinical and laboratory features of 109 reported cases. Jpn J Clin Oncol 1983, 13:543\u2013555.","journal-title":"Jpn J Clin Oncol"},{"key":"16_CR38","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0022-510X(98)00107-5","volume":"158","author":"J Benito-Leon","year":"1998","unstructured":"Benito-Leon J, Lopez-Rios F, Rodriguez-Martin FJ, et al.: Rapidly deteriorating polyneuropathy associated with osteosclerotic myeloma responsive to intravenous immunoglobulin and radiotherapy. J Neurol Sci 1998, 158:113\u2013117.","journal-title":"J Neurol Sci"},{"key":"16_CR39","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0360-3016(89)90008-4","volume":"16","author":"DA Frassica","year":"1989","unstructured":"Frassica DA, Frassica FJ, Schray MF, et al.: Solitary plasmacytoma of bone: Mayo Clinic experience. Int J Radiat Oncol Biol Phys 1989, 16:43\u201348.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"16_CR40","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/0360-3016(80)90006-1","volume":"6","author":"CM Mendenhall","year":"1980","unstructured":"Mendenhall CM, Thar TL, Million RR: Solitary plasmacytoma of bone and soft tissue. Int J Radiat Oncol Biol Phys 1980, 6:1497\u20131501.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"16_CR41","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1046\/j.1365-2141.2002.03692.x","volume":"118","author":"AJ Sternberg","year":"2002","unstructured":"Sternberg AJ, Davies P, Macmillan C, et al.: Strontium-89: a novel treatment for a case of osteosclerotic myeloma associated with life-threatening neuropathy. Br J Haematol 2002, 118:821\u2013824.","journal-title":"Br J Haematol"},{"key":"16_CR42","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/S0002-9394(98)00106-8","volume":"126","author":"VA Wong","year":"1998","unstructured":"Wong VA, Wade NK: POEMS syndrome: an unusual cause of bilateral optic disk swelling. Am J Ophthalmol 1998, 126:452\u2013454.","journal-title":"Am J Ophthalmol"},{"key":"16_CR43","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0303-8467(91)90061-S","volume":"93","author":"E Broussolle","year":"1991","unstructured":"Broussolle E, Vighetto A, Bancel B, et al.: P.O.E.M.S. syndrome with complete recovery after treatment of a solitary plasmocytoma. Clin Neurol Neurosurg 1991, 93:165\u2013170.","journal-title":"Clin Neurol Neurosurg"},{"key":"16_CR44","first-page":"56","volume":"33","author":"H Furuzono","year":"1993","unstructured":"Furuzono H, Moritoyo T, Yamada H, et al.: [A case of Crow-Fukase syndrome which developed seven years following myelopathy of unknown origin]. Rinsho Shinkeigaku 1993, 33:56\u201360.","journal-title":"Rinsho Shinkeigaku"},{"key":"16_CR45","first-page":"366","volume":"58","author":"YJ Chang","year":"1996","unstructured":"Chang YJ, Huang CC, Chu CC: Intravenous immunoglobulin therapy in POEMS syndrome: a case report. Zhonghua Yi Xue Za Zhi (Taipei) 1996, 58:366\u2013369.","journal-title":"Zhonghua Yi Xue Za Zhi (Taipei)"},{"key":"16_CR46","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/jca.2920020309","volume":"2","author":"LE Silberstein","year":"1985","unstructured":"Silberstein LE, Duggan D, Berkman EM: Therapeutic trial of plasma exchange in osteosclerotic myeloma associated with the POEMS syndrome. J Clin Apheresis 1985, 2:253\u2013257.","journal-title":"J Clin Apheresis"}],"container-title":["Current Treatment Options in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11864-004-0016-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11864-004-0016-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11864-004-0016-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11864-004-0016-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,15]],"date-time":"2022-05-15T13:17:06Z","timestamp":1652620626000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11864-004-0016-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["16"],"URL":"https:\/\/doi.org\/10.1007\/s11864-004-0016-4","relation":{},"ISSN":["1527-2729","1534-6277"],"issn-type":[{"value":"1527-2729","type":"print"},{"value":"1534-6277","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}