{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:12:26Z","timestamp":1772223146244,"version":"3.50.1"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Allergy Asthma Rep"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1007\/s11882-001-0095-2","type":"journal-article","created":{"date-parts":[[2007,6,28]],"date-time":"2007-06-28T05:58:31Z","timestamp":1183010311000},"page":"39-43","source":"Crossref","is-referenced-by-count":18,"title":["Atopic eczema and allergy"],"prefix":"10.1007","volume":"1","author":[{"given":"Johannes","family":"Ring","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Darsow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidrun","family":"Behrendt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"95_CR1","first-page":"146","volume":"114","author":"JM Hanifin","year":"1980","unstructured":"Hanifin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 1980, 114:146\u2013148.","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"95_CR2","first-page":"5","volume":"2","author":"JM Hanifin","year":"1983","unstructured":"Hanifin JM: Clinical and basic aspects of atopic dermatitis. Semin Dermatol 1983, 2:5.","journal-title":"Semin Dermatol"},{"key":"95_CR3","volume-title":"Angewandte Allergologie","author":"J Ring","year":"1991","unstructured":"Ring J: Angewandte Allergologie, edn 2. M\u00fcnchen: MMV Medizin Verlag; 1991.","edition":"edn 2"},{"key":"95_CR4","first-page":"3","volume-title":"Handbook of atopic eczema","author":"J Ring","year":"1993","unstructured":"Ring J: Atopy: condition, disease or syndrome? In Handbook of atopic eczema. Edited by Ruzicka T, Ring J, Przybilla B. Berlin: Springer; 1993:3\u20138."},{"key":"95_CR5","first-page":"1","volume":"9","author":"B W\u00fcthrich","year":"1983","unstructured":"W\u00fcthrich B: Neurodermitis atopica sive constitutionalis [in German]. Akt Dermatol 1983, 9:1\u20137.","journal-title":"Akt Dermatol"},{"key":"95_CR6","first-page":"1543","volume-title":"Dermatology in General Medicine","author":"DYM Leung","year":"1993","unstructured":"Leung DYM, Rhodes AR, Geha RS, et al.: Atopic dermatitis (atopic eczema). In Dermatology in General Medicine, edn 4. Edited by Fitzpatrick TB, Eisen AZ, Wolff K, et al. New York: McGraw Hill; 1993:1543\u20131563.","edition":"edn 4"},{"key":"95_CR7","first-page":"47","volume-title":"Fortschritte der praktischen Dermatologie und Venerologie","author":"A Marchionini","year":"1960","unstructured":"Marchionini A: Neuere Untersuchungen \u00fcber die Neurodermitis constitutionalis [in German]. In Fortschritte der praktischen Dermatologie und Venerologie, edn 3. Edited by Marchionini A. Berlin: Springer; 1960:47\u201362.","edition":"edn 3"},{"key":"95_CR8","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/BF00412924","volume":"278","author":"C Bruijnzeel-Koomen","year":"1986","unstructured":"Bruijnzeel-Koomen C, van Wichen DF, Toonstra J, et al.: The presence of IgE molecules on epidermal Langerhans cells in patients with atopic dermatitis. Arch Dermatol Res 1986, 278:199\u2013205.","journal-title":"Arch Dermatol Res"},{"key":"95_CR9","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1084\/jem.170.1.309","volume":"170","author":"T Bieber","year":"1989","unstructured":"Bieber T, Rieger A, Neuchrist C, et al.: Induction of FceR2\/CD23 on human epidermal Langerhans cells by human recombinant interleukin 4 and gamma interferon. J Exp Med 1989, 170:309\u2013314.","journal-title":"J Exp Med"},{"key":"95_CR10","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1084\/jem.175.5.1285","volume":"175","author":"T Bieber","year":"1992","unstructured":"Bieber T, de la Salle C, Wollenberg A, et al.: Constitutive expression of the high affinity receptor for IgE (FceR1) on human Langerhans cells. J Exp Med 1992, 175:1285\u20131290.","journal-title":"J Exp Med"},{"key":"95_CR11","doi-asserted-by":"crossref","first-page":"6285","DOI":"10.4049\/jimmunol.154.12.6285","volume":"154","author":"D Maurer","year":"1995","unstructured":"Maurer D, Ebner C, Reininger B, et al.: The high affinity IgE receptor mediates IgE-dependent allergen presentation. J Immunol 1995, 154:6285\u20136290.","journal-title":"J Immunol"},{"key":"95_CR12","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/0923-1811(90)90593-3","volume":"1","author":"Y Tanaka","year":"1990","unstructured":"Tanaka Y, Anan S, Yoshida H: Immunohistochemical studies in mite antigen-induced patch test sites in atopic dermatitis. J Dermatol Sci 1990, 1:361\u2013368.","journal-title":"J Dermatol Sci"},{"key":"95_CR13","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1016\/S0140-6736(95)91958-9","volume":"346","author":"A Wollenberg","year":"1997","unstructured":"Wollenberg A, Wen S, Bieber T: Langerhans cells phenotyping: a new tool for differential diagnosis of inflammatory skin diseases. Lancet 1997, 346:1626\u20131627.","journal-title":"Lancet"},{"key":"95_CR14","first-page":"195","volume":"82","author":"J Ring","year":"1988","unstructured":"Ring J, Kunz B, Bieber T, et al.: The \u201catopy patch test\u201d with aeroallergens in atopic eczema [abstract]. J Allergy Clin Immunol 1988, 82:195.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR15","first-page":"433","volume":"35","author":"A Rostenberg","year":"1937","unstructured":"Rostenberg A, Sulzberger MD: Some results of patch tests. Arch Dermatol 1937, 35:433\u2013454.","journal-title":"Arch Dermatol"},{"key":"95_CR16","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S0140-6736(82)90379-8","volume":"1","author":"E Mitchell","year":"1982","unstructured":"Mitchell E, Chapman M, Pope F, et al.: Basophils in allergen-induced patch test sites in atopic dermatitis. Lancet 1982, 1:127\u2013130.","journal-title":"Lancet"},{"key":"95_CR17","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/0091-6749(92)90434-4","volume":"89","author":"N Sager","year":"1992","unstructured":"Sager N, Feldmann A, Schilling G, et al.: House dust mite-specific T cells in the skin of subjects with atopic dermatitis: frequency and lymphokine profile in the allergen patch test. J Allergy Clin Immunol 1992, 89:801\u2013810.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR18","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/0091-6749(88)91047-0","volume":"81","author":"A Adinoff","year":"1988","unstructured":"Adinoff A, Tellez P, Clark R: Atopic dermatitis and aeroallergen contact sensitivity. J Allergy Clin Immunol 1988, 81:736\u2013742.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR19","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1111\/j.1365-2133.1986.tb06243.x","volume":"115","author":"A Gondo","year":"1986","unstructured":"Gondo A, Saeki N, Tokuda Y: Challenge reactions in atopic dermatitis after percutaneous entry of mite antigen. Br J Dermatol 1986, 115:485\u2013493.","journal-title":"Br J Dermatol"},{"key":"95_CR20","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/0190-9622(92)70218-5","volume":"27","author":"S Imayama","year":"1992","unstructured":"Imayama S, Hashizume T, Miyahara H, et al.: Combination of patch test and IgE for dust mite antigens differentiates 130 patients with atopic dermatitis into four groups. J Am Acad Dermatol 1992, 27:531\u2013538.","journal-title":"J Am Acad Dermatol"},{"key":"95_CR21","first-page":"9","volume":"2","author":"D Vieluf","year":"1993","unstructured":"Vieluf D, Kunz B, Bieber T, et al.: \u201cAtopy Patch Test\u201d with aeroallergens in patients with atopic eczema. Allergo J 1993, 2:9\u201312.","journal-title":"Allergo J"},{"key":"95_CR22","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/S0091-6749(95)70172-9","volume":"95","author":"U Darsow","year":"1995","unstructured":"Darsow U, Vieluf D, Ring J: Atopy patch test with different vehicles and allergen concentrations - an approach to standardization. J Allergy Clin Immunol 1995, 95:677\u2013684.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR23","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1046\/j.1365-2133.1996.d01-972.x","volume":"135","author":"U Darsow","year":"1996","unstructured":"Darsow U, Vieluf D, Ring J: The atopy patch test: an increased rate of reactivity in patients who have an air exposed pattern of atopic eczema. Br J Dermatol 1996, 135:182\u2013186.","journal-title":"Br J Dermatol"},{"key":"95_CR24","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S0190-9622(99)70186-6","volume":"40","author":"U Darsow","year":"1999","unstructured":"Darsow U, Vieluf D, Ring J for the APT study group: Evaluating the relevance of aeroallergen sensitization in atopic eczema using the tool \u201catopy patch test\u201d: a randomized, double-blind multicenter study. J Am Acad Dermatol 1999, 40:187\u2013193.","journal-title":"J Am Acad Dermatol"},{"key":"95_CR25","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1046\/j.1365-2133.1997.18061889.x","volume":"137","author":"U Darsow","year":"1997","unstructured":"Darsow U, Behrendt H, Ring J: Gramineae pollen as trigger factors of atopic eczema - evaluation of diagnostic measures using the atopy patch test. Br J Dermatol 1997, 137:201\u2013207.","journal-title":"Br J Dermatol"},{"key":"95_CR26","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1046\/j.1365-2133.1996.d01-1040.x","volume":"135","author":"M Gfesser","year":"1996","unstructured":"Gfesser M, Rakoski J, Ring J: Disturbance of epidermal barrier function in atopy patch test reactions in atopic eczema. Br J Dermatol 1996, 135:560\u2013565.","journal-title":"Br J Dermatol"},{"key":"95_CR27","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.1365-2133.1988.tb01779.x","volume":"118","author":"C Bruijnzeel-Koomen","year":"1988","unstructured":"Bruijnzeel-Koomen C, van Wichen D, Spry C, et al.: Active participation of eosinophils in patch test reactions to in halant allergens in patients with atopic dermatitis. Br J Dermatol 1988, 118:229\u2013238.","journal-title":"Br J Dermatol"},{"key":"95_CR28","first-page":"435","volume-title":"Allergic Skin Disease","author":"U Darsow","year":"2000","unstructured":"Darsow U, Ring J: The Atopy Patch Test: its role in the evaluation and management of atopic eczema. In Allergic Skin Disease. Edited by Leung DYM, Greaves MW. New York: Marcel Dekker; 2000:435\u2013447."},{"key":"95_CR29","first-page":"105","volume":"144","author":"T Langeland","year":"1989","unstructured":"Langeland T, Braathen L, Borch M: Studies of atopic patch tests. Acta Derm Venereol Suppl (Stockh) 1989, 144:105\u2013109.","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"95_CR30","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/0091-6749(92)90070-I","volume":"90","author":"FC van Reijsen","year":"1992","unstructured":"van Reijsen FC, Bruijnzeel-Koomen CAFM, Kalthoff FS, et al.: Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis. J Allergy Clin Immunol 1992, 90:184\u2013192.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR31","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0923-1811(92)90038-D","volume":"3","author":"K Maeda","year":"1992","unstructured":"Maeda K, Yamamoto K, Tanaka Y, et al.: House dust mite (HDM) antigen in naturally occurring lesions of atopic dermatitis (AD): the relationship between HDM antigen in the skin and HDM antigen-specific IgE antibody. J Dermatol Sci 1992, 3:73\u201377.","journal-title":"J Dermatol Sci"},{"key":"95_CR32","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1111\/j.1365-2133.1986.tb02821.x","volume":"114","author":"S Reitamo","year":"1986","unstructured":"Reitamo S, Visa K, K\u00e4h\u00f6nen K, et al.: Eczematous reactions in atopic patients caused by epicutaneous testing with inhalant allergens. Br J Dermatol 1986, 114:303\u2013309.","journal-title":"Br J Dermatol"},{"key":"95_CR33","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/0091-6749(83)90546-8","volume":"71","author":"DYM Leung","year":"1983","unstructured":"Leung DYM, Bhan AK, Schneeberger EE, Geha RS: Characterization of the mononuclear cell infiltrate in atopic dermatitis using mononuclear antibodies. J Allergy Clin Immunol 1983, 71:47\u201356.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR34","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/S0091-6749(98)70384-7","volume":"101","author":"A Wistokat-W\u00fclfing","year":"1998","unstructured":"Wistokat-W\u00fclfing A, Schmidt P, Darsow U, et al.: Atopy patch test reactions are associated with T-lymphocyte mediated allergen-specific immune responses in atopic dermatitis. J Allergy Clin Immunol 1998, 101:196\u2013197.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR35","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1111\/1523-1747.ep12321078","volume":"105","author":"M Grewe","year":"1995","unstructured":"Grewe M, Walther S, Gyufko K, et al.: Analysis of the cytokine pattern expressed in situ in inhalant allergen patch test reactions of atopic dermatitis patients. J Invest Dermatol 1995, 105:407\u2013410.","journal-title":"J Invest Dermatol"},{"key":"95_CR36","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/S0091-6749(96)80186-2","volume":"98","author":"EG Langeveld-Wildschut","year":"1996","unstructured":"Langeveld-Wildschut EG, Thepen T, Bihari IC, et al.: Evaluation of the atopy patch test and the cutaneous late-phase reaction as relevant models for the study of allergic inflammation in patients with atopic eczema. J Allergy Clin Immunol 1996, 98:1019\u20131027.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR37","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1067\/mai.2000.104783","volume":"105","author":"R Valenta","year":"2000","unstructured":"Valenta R, Seiberler S, Natter S, et al.: Autoallergy: a pathogenetic factor in atopic dermatitis? J Allergy Clin Immunol 2000, 105:432\u2013437.","journal-title":"J Allergy Clin Immunol"},{"key":"95_CR38","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.1398-9995.1996.tb00070.x","volume":"51","author":"J Ring","year":"1996","unstructured":"Ring J, Brockow K, Abeck D: The therapeutic concept of \u201cpatient management\u201d in atopic eczema. Allergy 1996, 51:206\u2013215.","journal-title":"Allergy"}],"container-title":["Current Allergy and Asthma Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-001-0095-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11882-001-0095-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-001-0095-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-001-0095-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T18:28:34Z","timestamp":1683916114000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11882-001-0095-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["95"],"URL":"https:\/\/doi.org\/10.1007\/s11882-001-0095-2","relation":{},"ISSN":["1529-7322","1534-6315"],"issn-type":[{"value":"1529-7322","type":"print"},{"value":"1534-6315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}