{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:13:35Z","timestamp":1792088015453,"version":"4.4.0"},"reference-count":100,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Allergy Asthma Rep"],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1007\/s11882-006-0053-0","type":"journal-article","created":{"date-parts":[[2007,6,3]],"date-time":"2007-06-03T19:01:24Z","timestamp":1180897284000},"page":"145-152","source":"Crossref","is-referenced-by-count":63,"title":["The diagnosis and management of egg allergy"],"prefix":"10.1007","volume":"6","author":[{"given":"Ralf G.","family":"Heine","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Laske","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"53_CR1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.3109\/07853899908995890","volume":"31","author":"DJ Hill","year":"1999","unstructured":"Hill DJ, Hosking CS, Heine RG: Clinical spectrum of food allergy in children in Australia and South-East Asia: identification and targets for treatment. Ann Med 1999, 31:272\u2013281.","journal-title":"Ann Med"},{"key":"53_CR2","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1399-3038.2005.00251.x","volume":"16","author":"M \u00d8sterballe","year":"2005","unstructured":"\u00d8sterballe M, Hansen TK, Mortz CG, et al.: The prevalence of food hypersensitivity in an unselected population of children and adults. Pediatr Allergy Immunol 2005, 16:567\u2013573. This Danish study provides recent estimates for the prevalence of common food allergies in three cohorts of children (younger than 3 years, 3 years of age, and older than 3 years), as well as in adults..","journal-title":"Pediatr Allergy Immunol"},{"key":"53_CR3","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.jaci.2005.05.047","volume":"116","author":"B Pereira","year":"2005","unstructured":"Pereira B, Venter C, Grundy J, et al.: Prevalence of sensitization to food allergens, reported adverse reaction to foods, food avoidance, and food hypersensitivity among teenagers. J Allergy Clin Immunol 2005, 116:884\u2013892. This large study reports the perceived and confirmed rate of food hypersensitivity in relation to IgE sensitization and challenge in two cohorts of British adolescents aged 11 and 15 years.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR4","doi-asserted-by":"crossref","first-page":"491","DOI":"10.5694\/j.1326-5377.1998.tb141412.x","volume":"168","author":"RM Andrews","year":"1998","unstructured":"Andrews RM, Kempe AE, Sinn KK, Herceg A: Vaccinating children with a history of serious reactions after vaccination or of egg allergy. Med J Aust 1998, 168:491\u2013494.","journal-title":"Med J Aust"},{"key":"53_CR5","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/S0091-6749(95)70118-4","volume":"95","author":"B Mosimann","year":"1995","unstructured":"Mosimann B, Stoll B, Francillon C, Pecoud A: Yellow fever vaccine and egg allergy. J Allergy Clin Immunol 1995, 95:1064.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR6","first-page":"381","volume":"11","author":"SS Wong","year":"2005","unstructured":"Wong SS, Yuen KY: Influenza vaccination: options and issues. Hong Kong Med J 2005, 11:381\u2013390.","journal-title":"Hong Kong Med J"},{"key":"53_CR7","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0022-3476(98)70101-5","volume":"133","author":"JM James","year":"1998","unstructured":"James JM, Zeiger RS, Lester MR, et al.: Safe administration of influenza vaccine to patients with egg allergy. J Pediatr 1998, 133:624\u2013628.","journal-title":"J Pediatr"},{"key":"53_CR8","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1136\/adc.2004.057372","volume":"90","author":"PW Ewan","year":"2005","unstructured":"Ewan PW, Clark AT: IgE mediated food allergy: When is food challenge needed? Arch Dis Child 2005, 90:555\u2013556.","journal-title":"Arch Dis Child"},{"key":"53_CR9","first-page":"122","volume":"7","author":"N Kondo","year":"1997","unstructured":"Kondo N, Fukutomi O, Agata H, Yokoyama Y: Proliferative responses of lymphocytes to food antigens are useful for detection of allergens in nonimmediate types of food allergy. J Investig Allergol Clin Immunol 1997, 7:122\u2013126.","journal-title":"J Investig Allergol Clin Immunol"},{"key":"53_CR10","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1111\/j.1365-2222.1996.tb00647.x","volume":"26","author":"E Holen","year":"1996","unstructured":"Holen E, Elsayed S: Specific T cell lines for ovalbumin, ovomucoid, lysozyme and two OA synthetic epitopes, generated from egg allergic patients\u2019 PBMC. Clin Exp Allergy 1996, 26:1080\u20131088.","journal-title":"Clin Exp Allergy"},{"key":"53_CR11","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1006\/bbrc.2002.6725","volume":"292","author":"Y Mine","year":"2002","unstructured":"Mine Y, Wei ZJ: Identification and fine mapping of IgG and IgE epitopes in ovomucoid. Biochem Biophys Res Commun 2002, 292:1070\u20131074.","journal-title":"Biochem Biophys Res Commun"},{"key":"53_CR12","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1271\/bbb.68.2490","volume":"68","author":"J Hirose","year":"2004","unstructured":"Hirose J, Kitabatake N, Kimura A, Narita H: Recognition of native and\/or thermally induced denatured forms of the major food allergen, ovomucoid, by human IgE and mouse monoclonal IgG antibodies. Biosci Biotechnol Biochem 2004, 68:2490\u20132497.","journal-title":"Biosci Biotechnol Biochem"},{"key":"53_CR13","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1046\/j.1365-2222.2001.01102.x","volume":"31","author":"E Holen","year":"2001","unstructured":"Holen E, Bolann B, Elsayed S: Novel B and T cell epitopes of chicken ovomucoid (Gal d 1) induce T cell secretion of IL-6, IL-13, and IFN-gamma. Clin Exp Allergy 2001, 31:952\u2013964.","journal-title":"Clin Exp Allergy"},{"key":"53_CR14","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0091-6749(94)70054-0","volume":"93","author":"J Bernhisel-Broadbent","year":"1994","unstructured":"Bernhisel-Broadbent J, Dintzis HM, Dintzis RZ, Sampson HA: Allergenicity and antigenicity of chicken egg ovomucoid (Gal d 3) compared with ovalbumin (Gal d 1) in children with egg allergy and in mice. J Allergy Clin Immunol 1994, 93:1047\u20131059.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR15","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/protein\/gzg095","volume":"16","author":"Y Mine","year":"2003","unstructured":"Mine Y, Rupa P: Fine mapping and structural analysis of immunodominant IgE allergenic epitopes in chicken egg ovalbumin. Protein Eng 2003, 16:747\u2013752.","journal-title":"Protein Eng"},{"key":"53_CR16","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/j.1365-2249.1996.tb08301.x","volume":"103","author":"K Honma","year":"1996","unstructured":"Honma K, Kohno Y, Saito K, et al.: Allergenic epitopes of ovalbumin (OVA) in patients with hen\u2019s egg allergy: inhibition of basophil histamine release by haptenic ovalbumin peptide. Clin Exp Immunol 1996, 103:446\u2013453.","journal-title":"Clin Exp Immunol"},{"key":"53_CR17","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1432-1033.1981.tb05243.x","volume":"115","author":"AD Nisbet","year":"1981","unstructured":"Nisbet AD, Saundry RH, Moir AJ, et al.: The complete amino-acid sequence of hen ovalbumin. Eur J Biochem 1981, 115:335\u2013345.","journal-title":"Eur J Biochem"},{"key":"53_CR18","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/ps\/81.1.112","volume":"81","author":"H Xie","year":"2002","unstructured":"Xie H, Huff GR, Huff WE, et al.: Identification of ovotransferrin as an acute phase protein in chickens. Poult Sci 2002, 81:112\u2013120.","journal-title":"Poult Sci"},{"key":"53_CR19","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/0091-6749(94)90388-3","volume":"93","author":"Z Szepfalusi","year":"1994","unstructured":"Szepfalusi Z, Ebner C, Pandjaitan R, et al.: Egg yolk alpha-livetin (chicken serum albumin) is a cross-reactive allergen in the bird-egg syndrome. J Allergy Clin Immunol 1994, 93:932\u2013942.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR20","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1034\/j.1398-9995.2001.056008754.x","volume":"56","author":"S Quirce","year":"2001","unstructured":"Quirce S, Maranon F, Umpierrez A, et al.: Chicken serum albumin (Gal d 5*) is a partially heat-labile inhalant and food allergen implicated in the bird-egg syndrome. Allergy 2001, 56:754\u2013762.","journal-title":"Allergy"},{"key":"53_CR21","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1034\/j.1398-9995.1999.00305.x","volume":"54","author":"M Palm","year":"1999","unstructured":"Palm M, Moneret-Vautrin DA, Kanny G, et al.: Food allergy to egg and soy lecithins. Allergy 1999, 54:1116\u20131117.","journal-title":"Allergy"},{"key":"53_CR22","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1021\/jf0112264","volume":"50","author":"Y Mine","year":"2002","unstructured":"Mine Y, Zhang JW: Comparative studies on antigenicity and allergenicity of native and denatured egg white proteins. J Agric Food Chem 2002, 50:2679\u20132683.","journal-title":"J Agric Food Chem"},{"key":"53_CR23","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1080\/09637480412331350173","volume":"55","author":"K Yoshino","year":"2004","unstructured":"Yoshino K, Sakai K, Mizuha Y, et al.: Peptic digestibility of raw and heat-coagulated hen\u2019s egg white proteins at acidic pH range. Int J Food Sci Nutr 2004, 55:635\u2013640.","journal-title":"Int J Food Sci Nutr"},{"key":"53_CR24","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1046\/j.1365-2745.2002.01433.x","volume":"32","author":"K Suzuki","year":"2002","unstructured":"Suzuki K, Inoue R, Sakaguchi H, et al.: The correlation between ovomucoid-derived peptides, human leucocyte antigen class II molecules and T cell receptor-complementarity determining region 3 compositions in patients with egg-white allergy. Clin Exp Allergy 2002, 32:1223\u20131230.","journal-title":"Clin Exp Allergy"},{"key":"53_CR25","first-page":"107","volume":"15","author":"M Kondo","year":"2005","unstructured":"Kondo M, Suzuki K, Inoue R, et al.: Characterization of T-cell clones specific to ovomucoid from patients with egg-white allergy. J Investig Allergol Clin Immunol 2005, 15:107\u2013111.","journal-title":"J Investig Allergol Clin Immunol"},{"key":"53_CR26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000233582","volume":"75","author":"PJ Kilshaw","year":"1984","unstructured":"Kilshaw PJ, Cant AJ: The passage of maternal dietary proteins into human breast milk. Int Arch Allergy Appl Immunol 1984, 75:8\u201315.","journal-title":"Int Arch Allergy Appl Immunol"},{"key":"53_CR27","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1111\/j.1365-2222.2005.02346.x","volume":"35","author":"GH Vance","year":"2005","unstructured":"Vance GH, Lewis SA, Grimshaw KE, et al.: Exposure of the fetus and infant to hens\u2019 egg ovalbumin via the placenta and breast milk in relation to maternal intake of dietary egg. Clin Exp Allergy 2005, 35:1318\u20131326. The authors provide evidence for the transfer of intact food allergens in amniotic fluid and breast milk and develop a model of early sensitization of the infant in utero or via breast milk.","journal-title":"Clin Exp Allergy"},{"key":"53_CR28","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/adc.2002.013029","volume":"89","author":"JO Warner","year":"2004","unstructured":"Warner JO: The early life origins of asthma and related allergic disorders. Arch Dis Child 2004, 89:97\u2013102.","journal-title":"Arch Dis Child"},{"key":"53_CR29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1365-2222.2005.02170.x","volume":"35","author":"DJ Palmer","year":"2005","unstructured":"Palmer DJ, Gold MS, Makrides M: Effect of cooked and raw egg consumption on ovalbumin content of human milk: a randomized, double-blind, cross-over trial. Clin Exp Allergy 2005, 35:173\u2013178. This well-conducted, randomized study provides evidence for a transfer of intact egg allergens into breast milk and demonstrates a dose-response relationship for breast milk content of ovalbumin versus maternal dietary intake of egg.","journal-title":"Clin Exp Allergy"},{"key":"53_CR30","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/ajcn\/65.1.30","volume":"65","author":"Y Fukushima","year":"1997","unstructured":"Fukushima Y, Kawata Y, Onda T, Kitagawa M: Consumption of cow milk and egg by lactating women and the presence of beta-lactoglobulin and ovalbumin in breast milk. Am J Clin Nutr 1997, 65:30\u201335.","journal-title":"Am J Clin Nutr"},{"key":"53_CR31","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1271\/bbb.65.1438","volume":"65","author":"J Hirose","year":"2001","unstructured":"Hirose J, Ito S, Hirata N, et al.: Occurrence of the major food allergen, ovomucoid, in human breast milk as an immune complex. Biosci Biotechnol Biochem 2001, 65:1438\u20131440.","journal-title":"Biosci Biotechnol Biochem"},{"key":"53_CR32","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1001\/jama.285.13.1746","volume":"285","author":"P Vadas","year":"2001","unstructured":"Vadas P, Wai Y, Burks W, Perelman B: Detection of peanut allergens in breast milk of lactating women. JAMA 2001, 285:1746\u20131748.","journal-title":"JAMA"},{"key":"53_CR33","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1111\/j.1365-2222.2004.02111.x","volume":"34","author":"GH Vance","year":"2004","unstructured":"Vance GH, Grimshaw KE, Briggs R, et al.: Serum ovalbumin-specific immunoglobulin G responses during pregnancy reflect maternal intake of dietary egg and relate to the development of allergy in early infancy. Clin Exp Allergy 2004, 34:1855\u20131861. This study demonstrates that ovalbumin-specific IgG correlates with maternal egg intake. The authors speculate that transplacental transfer of egg-specific IgG may modulate fetal immune responses.","journal-title":"Clin Exp Allergy"},{"key":"53_CR34","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1046\/j.1365-2222.2003.01734.x","volume":"33","author":"M Morisset","year":"2003","unstructured":"Morisset M, Moneret-Vautrin DA, Kanny G, et al.: Thresholds of clinical reactivity to milk, egg, peanut and sesame in immunoglobulin E-dependent allergies: evaluation by double-blind or single-blind placebo-controlled oral challenges. Clin Exp Allergy 2003, 33:1046\u20131051.","journal-title":"Clin Exp Allergy"},{"key":"53_CR35","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1365-2222.2004.1886.x","volume":"34","author":"SL Taylor","year":"2004","unstructured":"Taylor SL, Hefie SL, Bindslev-Jensen C, et al.: A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much? Clin Exp Allergy 2004, 34:689\u2013695. This consensus paper outlines the procedure for low-dose food challenge to determine minimal thresholds doses for food allergens.","journal-title":"Clin Exp Allergy"},{"key":"53_CR36","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1046\/j.1365-2745.2002.01454.x","volume":"32","author":"G Monti","year":"2002","unstructured":"Monti G, Muratore MC, Peltran A, et al.: High incidence of adverse reactions to egg challenge on first known exposure in young atopic dermatitis children: predictive value of skin prick test and radioallergosorbent test to egg proteins. Clin Exp Allergy 2002, 32:1515\u20131519.","journal-title":"Clin Exp Allergy"},{"key":"53_CR37","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1111\/j.1365-2222.2005.02257.x","volume":"35","author":"A Uguz","year":"2005","unstructured":"Uguz A, Lack G, Pumphrey R, et al.: Allergic reactions in the community: a questionnaire survey of members of the anaphylaxis campaign. Clin Exp Allergy 2005, 35:746\u2013750.","journal-title":"Clin Exp Allergy"},{"key":"53_CR38","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000085792","volume":"137","author":"M Kimura","year":"2005","unstructured":"Kimura M, Obi M: Ovalbumin-induced IL-4, IL-5 and IFN-gamma production in infants with atopic dermatitis. Int Arch Allergy Immunol 2005, 137:134\u2013140.","journal-title":"Int Arch Allergy Immunol"},{"key":"53_CR39","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.jpeds.2004.03.001","volume":"144","author":"RG Heine","year":"2004","unstructured":"Heine RG, Hill DJ, Hosking CS: Primary prevention of atopic dermatitis in breast-fed infants: What is the evidence? J Pediatr 2004, 144:564\u2013567.","journal-title":"J Pediatr"},{"key":"53_CR40","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1399-3038.2004.00178.x","volume":"15","author":"DJ Hill","year":"2004","unstructured":"Hill DJ, Hosking CS: Food allergy and atopic dermatitis in infancy: an epidemiologic study. Pediatr Allergy Immunol 2004, 15:421\u2013427. The authors demonstrate a close relationship between AD in infancy and food allergy. The strength of the association suggests a causal relationship between AD and food allergy.","journal-title":"Pediatr Allergy Immunol"},{"key":"53_CR41","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1172\/JCI21060","volume":"113","author":"DY Leung","year":"2004","unstructured":"Leung DY, Boguniewicz M, Howell MD, et al.: New insights into atopic dermatitis. J Clin Invest 2004, 113:651\u2013657.","journal-title":"J Clin Invest"},{"key":"53_CR42","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.jaci.2005.02.014","volume":"115","author":"J Wang","year":"2005","unstructured":"Wang J, Visness CM, Sampson HA: Food allergen sensitization in inner-city children with asthma. J Allergy Clin Immunol 2005, 115:1076\u20131080. In a study of 504 children with asthma, food sensitization was common and was a marker of asthma requiring frequent treatment with corticosteroids or hospitalization.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR43","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1034\/j.1399-3038.2000.00077.x","volume":"11","author":"SM Tariq","year":"2000","unstructured":"Tariq SM, Matthews SM, Hakim EA, Arshad SH: Egg allergy in infancy predicts respiratory allergic disease by 4 years of age. Pediatr Allergy Immunol 2000, 11:162\u2013167.","journal-title":"Pediatr Allergy Immunol"},{"key":"53_CR44","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1111\/j.1365-2222.2004.02058.x","volume":"34","author":"GH Vance","year":"2004","unstructured":"Vance GH, Thornton CA, Bryant TN, et al.: Ovalbuminspeci fic immunoglobulin G and subclass responses through the first 5 years of life in relation to duration of egg sensitization and the development of asthma. Clin Exp Allergy 2004, 34:1542\u20131549. Elevated ovalbumin-specific IgG levels are associated with asthma and may be useful as a screening tool for children who are at risk for asthma.","journal-title":"Clin Exp Allergy"},{"key":"53_CR45","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1164\/ajrccm.165.2.2104032","volume":"165","author":"HL Rhodes","year":"2002","unstructured":"Rhodes HL, Thomas P, Sporik R, et al.: Early life risk factors for adult asthma: a birth cohort study of subjects at risk. Am J Respir Crit Care Med 2002, 165:176\u2013180.","journal-title":"Am J Respir Crit Care Med"},{"key":"53_CR46","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1034\/j.1398-9995.2003.00201.x","volume":"58","author":"C Escudero","year":"2003","unstructured":"Escudero C, Quirce S, Fernandez-Nieto M, et al.: Egg white proteins as inhalant allergens associated with baker\u2019s asthma. Allergy 2003, 58:616\u2013620.","journal-title":"Allergy"},{"key":"53_CR47","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000234664","volume":"87","author":"MM Mandallaz","year":"1988","unstructured":"Mandallaz MM, de Weck AL, Dahinden CA: Bird-egg syndrome: cross-reactivity between bird antigens and egg-yolk livetins in IgE-mediated hypersensitivity. Int Arch Allergy Appl Immunol 1988, 87:143\u2013150.","journal-title":"Int Arch Allergy Appl Immunol"},{"key":"53_CR48","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2500\/108854194778703017","volume":"15","author":"F Blay de","year":"1994","unstructured":"de Blay F, Hoyet C, Candol. E, et al.: Identification of alpha livetin as a cross reacting allergen in a bird-egg syndrome. Allergy Proc 1994, 15:77\u201378.","journal-title":"Allergy Proc"},{"key":"53_CR49","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1097\/00005176-200001001-00009","volume":"30","author":"AM Lake","year":"2000","unstructured":"Lake AM: Food-induced eosinophilic proctocolitis. J Pediatr Gastroenterol Nutr 2000, 30:S58-S60.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"53_CR50","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1067\/mai.2002.121458","volume":"109","author":"JM Spergel","year":"2002","unstructured":"Spergel JM, Beausoleil JL, Mascarenhas M, Liacouras CA: The use of skin prick tests and patch tests to identify causative foods in eosinophilic esophagitis. J Allergy Clin Immunol 2002, 109:363\u2013368.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR51","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0022-3476(83)80519-8","volume":"102","author":"JJ Herman","year":"1983","unstructured":"Herman JJ, Radin R, Schneiderman R: Allergic reactions to measles [rubeola] vaccine in patients hypersensitive to egg protein. J Pediatr 1983, 102:196\u2013199.","journal-title":"J Pediatr"},{"key":"53_CR52","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1542\/peds.110.6.e71","volume":"110","author":"V Pool","year":"2002","unstructured":"Pool V, Braun MM, Kelso JM, et al.: Prevalence of antigelatin IgE antibodies in people with anaphylaxis after measles-mumps rubella vaccine in the United States. Pediatrics 2002, 110:e71.","journal-title":"Pediatrics"},{"key":"53_CR53","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1136\/bmj.309.6949.223","volume":"309","author":"R Aickin","year":"1994","unstructured":"Aickin R, Hill D, Kemp A: Measles immunisation in children with allergy to egg. BMJ 1994, 309:223\u2013225.","journal-title":"BMJ"},{"key":"53_CR54","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/S0091-6749(03)01616-6","volume":"112","author":"RL Miller","year":"2003","unstructured":"Miller RL, Cheng M, DiMango EA, et al.: T-cell responses and hypersensitivity to influenza and egg antigens among adults with asthma immunized with the influenza vaccine. J Allergy Clin Immunol 2003, 112:606\u2013608.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR55","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/0091-6749(88)90135-2","volume":"82","author":"SA Bock","year":"1988","unstructured":"Bock SA, Sampson HA, Atkins FM, et al.: Double-blind, placebo-controlled food challenge (DBPCFC) as an office procedure: a manual. J Allergy Clin Immunol 1988, 82:986\u2013997.","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl78","key":"53_CR56","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1398-9995.2004.00571.x","volume":"59","author":"B Niggemann","year":"2004","unstructured":"Niggemann B: Role of oral food challenges in the diagnostic work-up of food allergy in atopic eczema dermatitis syndrome. Allergy 2004, 59(Suppl78):32\u201334.","journal-title":"Allergy"},{"key":"53_CR57","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.jaci.2004.07.063","volume":"114","author":"TT Perry","year":"2004","unstructured":"Perry TT, Matsui EC, Conover-Walker MK, Wood RA: Risk of oral food challenges. J Allergy Clin Immunol 2004, 114:1164\u20131168. This large retrospective study of the safety of food challenges provides an excellent summary on the severity of adverse reactions to foods.","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl79","key":"53_CR58","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1398-9995.2005.00853.x","volume":"60","author":"HA Sampson","year":"2005","unstructured":"Sampson HA: Food allergy: accurately identifying clinical reactivity. Allergy 2005, 60(Suppl79):19\u201324.","journal-title":"Allergy"},{"key":"53_CR59","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1398-9995.2004.00466.x","volume":"59","author":"C Bindslev-Jensen","year":"2004","unstructured":"Bindslev-Jensen C, Ballmer-Weber BK, Bengtsson U, et al.: Standardization of food challenges in patients with immediate reactions to foods: position paper from the European Academy of Allergology and Clinical Immunology. Allergy 2004, 59:690\u2013697. The aim of this useful consensus paper was to standardize the procedure for food challenges.","journal-title":"Allergy"},{"key":"53_CR60","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1399-3038.1997.tb00141.x","volume":"8","author":"F Ranc\u00e9","year":"1997","unstructured":"Ranc\u00e9 F, Dutau G: Labial food challenge in children with food allergy. Pediatr Allergy Immunol 1997, 8:41\u201344.","journal-title":"Pediatr Allergy Immunol"},{"key":"53_CR61","first-page":"73","volume":"49","author":"Centers for Disease Control and Prevention (CDC)","year":"2000","unstructured":"Centers for Disease Control and Prevention (CDC): Outbreaks of Salmonella serotype enteritidis infection associated with eating raw or undercooked shell eggs-United States, 1996\u20131998. MMWR Morb Mortal Wkly Rep 2000, 49:73\u201379.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"53_CR62","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0091-6749(97)70133-7","volume":"100","author":"HA Sampson","year":"1997","unstructured":"Sampson HA, Ho DG: Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents. J Allergy Clin Immunol 1997, 100:444\u2013451.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR63","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1067\/mai.2001.114708","volume":"107","author":"HA Sampson","year":"2001","unstructured":"Sampson HA: Utility of food-specific IgE concentrations in predicting symptomatic food allergy. J Allergy Clin Immunol 2001, 107:891\u2013896.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR64","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.jaci.2004.04.009","volume":"114","author":"TT Perry","year":"2004","unstructured":"Perry TT, Matsui EC, Kay Conover-Walker M, Wood RA: The relationship of allergen-specific IgE levels and oral food challenge outcome. J Allergy Clin Immunol 2004, 114:144\u2013149. The authors define cut-off levels for food-specific IgE that are associated with a greater than 50% chance of patients tolerating a food. This finding may be useful with regard to timing of challenges in patients with IgE-mediated food allergies.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR65","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1067\/mai.2003.1603","volume":"112","author":"M \u00d8sterballe","year":"2003","unstructured":"\u00d8sterballe M, Bindslev-Jensen C: Threshold levels in food challenge and specific IgE in patients with egg allergy: Is there a relationship? J Allergy Clin Immunol 2003, 112:196\u2013201.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR66","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1365-2222.2005.02150.x","volume":"35","author":"S Celik-Bilgili","year":"2005","unstructured":"Celik-Bilgili S, Mehl A, Verstege A, et al.: The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges. Clin Exp Allergy 2005, 35:268\u2013273. This German study provides predictive cut-off levels for food-speci fic IgE in predicting a positive food challenge outcome.","journal-title":"Clin Exp Allergy"},{"key":"53_CR67","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1046\/j.1365-2222.2001.01175.x","volume":"31","author":"Mart\u00ednez T Boyano","year":"2001","unstructured":"Boyano Mart\u00ednez T, Garc\u00eda-Ara C, D\u00edaz-Pena JM, et al.: Validity of specific IgE antibodies in children with egg allergy. Clin Exp Allergy 2001, 31:1464\u20131469.","journal-title":"Clin Exp Allergy"},{"key":"53_CR68","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1399-3038.2004.00188.x","volume":"15","author":"DJ Hill","year":"2004","unstructured":"Hill DJ, Heine RG, Hosking CS: The diagnostic value of skin prick testing in children with food allergy. Pediatr Allergy Immunol 2004, 15:435\u2013441.","journal-title":"Pediatr Allergy Immunol"},{"key":"53_CR69","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1046\/j.1365-2222.2000.00928.x","volume":"30","author":"R Sporik","year":"2000","unstructured":"Sporik R, Hill DJ, Hosking CS: Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children. Clin Exp Allergy 2000, 30:1540\u20131546.","journal-title":"Clin Exp Allergy"},{"key":"53_CR70","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1111\/j.1365-2222.2005.2324.x","volume":"35","author":"A Verstege","year":"2005","unstructured":"Verstege A, Mehl A, Rolinck-Werninghaus C, et al.: The predictive value of the skin prick test weal size for the outcome of oral food challenges. Clin Exp Allergy 2005, 35:1220\u20131226. This study defines SPT wheal diameters that predict a positive food challenge.","journal-title":"Clin Exp Allergy"},{"key":"53_CR71","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1111\/j.1398-9995.2004.00594.x","volume":"59","author":"K Perackis","year":"2004","unstructured":"Perackis K, Staden U, Mehl A, Niggemann B: Skin prick test with hen\u2019s egg: Whole egg or egg white? Allergy 2004, 59:1236\u20131237.","journal-title":"Allergy"},{"key":"53_CR72","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0091-6749(96)70277-4","volume":"97","author":"E Isolauri","year":"1996","unstructured":"Isolauri E, Turjanmaa K: Combined skin prick and patch testing enhances Identification of food allergy in infants with atopic dermatitis. J Allergy Clin Immunol 1996, 97:9\u201315.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR73","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/00130832-200206000-00016","volume":"2","author":"B Niggemann","year":"2002","unstructured":"Niggemann B: Evolving role of the atopy patch test in the diagnosis of food allergy. Curr Opin Allergy Clin Immunol 2002, 2:253\u2013256.","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"53_CR74","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1067\/mai.2001.120192","volume":"108","author":"B Niggemann","year":"2001","unstructured":"Niggemann B, Reibel S, Roehr CC, et al.: Predictors of positive food challenge outcome in non-IgE-mediated reactions to food in children with atopic dermatitis. J Allergy Clin Immunol 2001, 108:1053\u20131058.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR75","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1525-1470.2005.22202.x","volume":"22","author":"F Giusti","year":"2005","unstructured":"Giusti F, Seidenari S: Patch testing with egg represents a useful integration to diagnosis of egg allergy in children with atopic dermatitis. Pediatr Dermatol 2005, 22:109\u2013111.","journal-title":"Pediatr Dermatol"},{"key":"53_CR76","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1067\/mpd.2003.92","volume":"142","author":"D Boissieu de","year":"2003","unstructured":"de Boissieu D, Waguet JC, Dupont C: The atopy patch tests for detection of cow\u2019s milk allergy with digestive symptoms. J Pediatr 2003, 142:203\u2013205. This study provides preliminary evidence that APT may be a useful diagnostic test in infants with gastrointestinal manifestations of cow\u2019s milk allergy.","journal-title":"J Pediatr"},{"key":"53_CR77","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1067\/mai.2002.126659","volume":"110","author":"B Niggemann","year":"2002","unstructured":"Niggemann B, Ziegert M, Reibel S: Importance of chamber size for the outcome of atopy patch testing in children with atopic dermatitis and food allergy. J Allergy Clin Immunol 2002, 110:515\u2013516.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR78","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jaad.2004.03.025","volume":"51","author":"M \u00d8sterballe","year":"2004","unstructured":"\u00d8sterballe M, Andersen KE, Bindslev-Jensen C: The diagnostic accuracy of the atopy patch test in diagnosing hypersensitivity to cow\u2019s milk and hen\u2019s egg in unselected children with and without atopic dermatitis. J Am Acad Dermatol 2004, 51:556\u2013562.","journal-title":"J Am Acad Dermatol"},{"key":"53_CR79","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1067\/mai.2001.112849","volume":"107","author":"CC Roehr","year":"2001","unstructured":"Roehr CC, Reibel S, Ziegert M, et al.: Atopy patch tests, together with determination of specific IgE levels, reduce the need for oral food challenges in children with atopic dermatitis. J Allergy Clin Immunol 2001, 107:548\u2013553.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR80","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1542\/peds.111.S3.1645","volume":"111","author":"S Mofidi","year":"2003","unstructured":"Mofidi S: Nutritional management of pediatric food hypersensitivity. Pediatrics 2003, 111:1645\u20131653.","journal-title":"Pediatrics"},{"key":"53_CR81","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S0022-3476(98)70399-3","volume":"132","author":"E Isolauri","year":"1998","unstructured":"Isolauri E, S\u00fctas Y, Salo MK, et al.: Elimination diet in cow\u2019s milk allergy: risk for impaired growth in young children. J Pediatr 1998, 132:1004\u20131009.","journal-title":"J Pediatr"},{"key":"53_CR82","first-page":"CD000133","volume":"2","author":"MS Kramer","year":"2003","unstructured":"Kramer MS: Maternal antigen avoidance during pregnancy for preventing atopic disease in infants of women at high risk. Cochrane Database Syst Rev 2003, 2:CD000133.","journal-title":"Cochrane Database Syst Rev"},{"key":"53_CR83","doi-asserted-by":"crossref","first-page":"e709","DOI":"10.1542\/peds.2005-0147","volume":"116","author":"DJ Hill","year":"2005","unstructured":"Hill DJ, Roy N, Heine RG, et al.: Effect of a low-allergen maternal diet on colic among breastfed infants: a randomized, controlled trial. Pediatrics 2005, 116:e709-e715.","journal-title":"Pediatrics"},{"key":"53_CR84","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jaci.2005.01.009","volume":"115","author":"HA Sampson","year":"2005","unstructured":"Sampson HA, Mu\u00f1oz-Furlong A, Bock SA, et al.: Symposium on the definition and management of anaphylaxis: summary report. J Allergy Clin Immunol 2005, 115:584\u2013591.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR85","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1046\/j.1440-1754.2003.00157.x","volume":"39","author":"AS Kemp","year":"2003","unstructured":"Kemp AS: EpiPen epidemic: suggestions for rational prescribing in childhood food allergy. J Paediatr Child Health 2003, 39:372\u2013375.","journal-title":"J Paediatr Child Health"},{"key":"53_CR86","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jaci.2005.03.039","volume":"116","author":"JS Kim","year":"2005","unstructured":"Kim JS, Sinacore JM, Pongracic JA: Parental use of EpiPen for children with food allergies. J Allergy Clin Immunol 2005, 116:164\u2013168.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR87","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1056\/NEJM199208063270603","volume":"327","author":"HA Sampson","year":"1992","unstructured":"Sampson HA, Mendelson L, Rosen JP: Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 1992, 327:380\u2013384.","journal-title":"N Engl J Med"},{"key":"53_CR88","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/01.all.0000168797.14487.73","volume":"5","author":"S Clark","year":"2005","unstructured":"Clark S, Camargo CA Jr: Emergency management of food allergy: systems perspective. Curr Opin Allergy Clin Immunol 2005, 5:293\u2013298.","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"53_CR89","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1542\/peds.2004-1475","volume":"116","author":"CL McIntyre","year":"2005","unstructured":"McIntyre CL, Sheetz AH, Carroll CR, Young MC: Administration of epinephrine for life-threatening allergic reactions in school settings. Pediatrics 2005, 116:1134\u20131140.","journal-title":"Pediatrics"},{"key":"53_CR90","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S1081-1206(10)61130-1","volume":"946","author":"TT Song","year":"2005","unstructured":"Song TT, Nelson MR, Chang JH, et al.: Adequacy of the epinephrine autoinjector needle length in delivering epinephrine to the intramuscular tissues. Ann Allergy Asthma Immunol 2005, 946:539\u2013542.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"53_CR91","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1542\/peds.111.S3.1631","volume":"111","author":"RA Wood","year":"2003","unstructured":"Wood RA: The natural history of food allergy. Pediatrics 2003, 111:1631\u20131637.","journal-title":"Pediatrics"},{"key":"53_CR92","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1136\/adc.57.9.649","volume":"57","author":"RP Ford","year":"1982","unstructured":"Ford RP, Taylor B: Natural history of egg hypersensitivity. Arch Dis Child 1982, 57:649\u2013652.","journal-title":"Arch Dis Child"},{"key":"53_CR93","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1111\/j.1398-9995.2005.00882.x","volume":"60","author":"C Rolinck-Werninghaus","year":"2005","unstructured":"Rolinck-Werninghaus C, Staden U, Mehl A, et al.: Specific oral tolerance induction with food in children: transient or persistent effect on food allergy? Allergy 2005, 60:1320\u20131322.","journal-title":"Allergy"},{"key":"53_CR94","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1067\/mai.2002.126081","volume":"110","author":"T Boyano-Mart\u00ednez","year":"2002","unstructured":"Boyano-Mart\u00ednez T, Garc\u00eda-Ara C, D\u00edaz-Pena JM, Mart\u00edn- Esteban M: Prediction of tolerance on the basis of quantification of egg white-specific IgE antibodies in children with egg allergy. J Allergy Clin Immunol 2002, 110:304\u2013309.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR95","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1651-2227.2004.tb03014.x","volume":"93","author":"BY Thong","year":"2004","unstructured":"Thong BY, Hourihane JO: Monitoring of IgE-mediated food allergy in childhood. Acta Paediatr 2004, 93:759\u2013764.","journal-title":"Acta Paediatr"},{"key":"53_CR96","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.jaci.2004.04.032","volume":"114","author":"LP Shek","year":"2004","unstructured":"Shek LP, S\u00f6derstr\u00f6m L, Ahlstedt S, et al.: Determination of food specific IgE levels over time can predict the development of tolerance in cow\u2019s milk and hen\u2019s egg allergy. J Allergy Clin Immunol 2004, 114:387\u2013391. This study demonstrates that the rate of decline of specific IgE levels may be of prognostic value in predicting tolerance in cow\u2019s milk and egg-allergic patients.","journal-title":"J Allergy Clin Immunol"},{"key":"53_CR97","first-page":"98","volume":"4","author":"B Niggemann","year":"2004","unstructured":"Niggemann B, Celik-Bilgili S, Ziegert M, et al.: Specific IgE levels do not indicate persistence or transience of food allergy in children with atopic dermatitis. J Investig Allergol Clin Immunol 2004, 4:98\u2013103.","journal-title":"J Investig Allergol Clin Immunol"},{"key":"53_CR98","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1542\/peds.111.S3.1662","volume":"111","author":"RS Zeiger","year":"2003","unstructured":"Zeiger RS: Food allergen avoidance in the prevention of food allergy in infants and children. Pediatrics 2003, 111:1662\u20131671.","journal-title":"Pediatrics"},{"key":"53_CR99","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1034\/j.1399-3038.2003.02069.x","volume":"14","author":"G Halmerbauer","year":"2003","unstructured":"Halmerbauer G, Gartner C, Schierl M, et al.: Study on the Prevention of Allergy in Children in Europe [SPACE]: allergic sensitization at 1 year of age in a controlled trial of allergen avoidance from birth. Pediatr Allergy Immunol 2003, 14:10\u201317.","journal-title":"Pediatr Allergy Immunol"},{"key":"53_CR100","doi-asserted-by":"crossref","first-page":"464","DOI":"10.5694\/j.1326-5377.2005.tb06787.x","volume":"182","author":"SL Prescott","year":"2005","unstructured":"Prescott SL, Tang ML: The Australian Society of Clinical Immunology and Allergy position statement: summary of allergy prevention in children. Med J Aust 2005, 182:464\u2013467.","journal-title":"Med J Aust"}],"container-title":["Current Allergy and Asthma Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-006-0053-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11882-006-0053-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-006-0053-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T04:41:00Z","timestamp":1683866460000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11882-006-0053-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":100,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["53"],"URL":"https:\/\/doi.org\/10.1007\/s11882-006-0053-0","relation":{},"ISSN":["1529-7322","1534-6315"],"issn-type":[{"value":"1529-7322","type":"print"},{"value":"1534-6315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}