{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T18:49:43Z","timestamp":1790102983867,"version":"4.0.1"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Allergy Asthma Rep"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1007\/s11882-007-0073-4","type":"journal-article","created":{"date-parts":[[2009,5,29]],"date-time":"2009-05-29T16:12:57Z","timestamp":1243613577000},"page":"202-208","source":"Crossref","is-referenced-by-count":104,"title":["Inflammatory mechanisms and remodeling in chronic rhinosinusitis and nasal polyps"],"prefix":"10.1007","volume":"7","author":[{"given":"Ruby","family":"Pawankar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Nonaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"73_CR1","volume-title":"Current estimates from the National Health Interview Survey. United States-1985","author":"A.J. Moss","year":"1986","unstructured":"Moss AJ, Parsons VL: Current estimates from the National Health Interview Survey. United States-1985. Hyattsville, MD: National Center for Health Statistics; 1986. [DHHS publication no. (PHS) 68-1588, Vital and Health Statistics, series 10, no. 160:66-72.]"},{"key":"73_CR2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jaci.2004.09.029","volume":"114","author":"E.O. Meltzer","year":"2004","unstructured":"Meltzer EO, Hamilos DL, Hadley JA, et al.: Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol 2004, 114: 155\u2013212. Describes the new classification of CRS.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR3","first-page":"19","volume-title":"Sinusitis: Pathophysiology and Treatment","author":"J.N. Baraniuk","year":"1994","unstructured":"Baraniuk JN: Physiology of sinusitis. In Sinusitis: Pathophysiology and Treatment. Edited by Druce HM. New York: Marcel Dekker; 1994: 19\u201339."},{"key":"73_CR4","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3109\/00016489609137849","volume":"116","author":"P. Cauwenberge Van","year":"1996","unstructured":"Van Cauwenberge P, Ingels K: Effects of viral and bacterial infection on nasal and sinus mucosa. Acta Otolaryngol (Stockh) 1996, 116: 316\u2013321.","journal-title":"Acta Otolaryngol (Stockh)"},{"issue":"8","key":"73_CR5","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1001\/archotol.1993.01880200030004","volume":"119","author":"E. Calenoff","year":"1993","unstructured":"Calenoff E, McMahan JT, Herzon GD, et al.: Bacterial allergy in nasal polyposis. A new method for quantifying specific IgE. Arch Otolaryngol Head Neck Surg 1993, 119 (8): 830\u2013836.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"73_CR6","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1183\/09031936.02.00229302","volume":"19","author":"P.G. Holt","year":"2002","unstructured":"Holt PG, Sly PD: Interactions between respiratory tract infections and atopy in the aetiology of asthma. Eur Respir J 2002, 19: 538\u2013545.","journal-title":"Eur Respir J"},{"key":"73_CR7","first-page":"530","volume":"6","author":"G. Corrado","year":"2000","unstructured":"Corrado G, Luzzi I, Lucarelli S, et al.: Correlation between Helicobacter pylori infection and food allergy in chronic gastritis. Med Sci Monit 2000, 6: 530\u2013538.","journal-title":"Med Sci Monit"},{"key":"73_CR8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev.micro.55.1.77","volume":"55","author":"J.K. McCormick","year":"2001","unstructured":"McCormick JK, Yarwood JM, Schlievert PM: Toxic shock syndrome and bacterial superantigens: an update. Annu Rev Microbiol 2001, 55: 77\u2013104.","journal-title":"Annu Rev Microbiol"},{"key":"73_CR9","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S1473-3099(02)00222-0","volume":"2","author":"M. Llewelyn","year":"2002","unstructured":"Llewelyn M, Cohen J: Superantigens: microbial agents that corrupt immunity. Lancet Infect Dis 2002, 2: 156\u2013162.","journal-title":"Lancet Infect Dis"},{"key":"73_CR10","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1007\/s10096-003-0928-0","volume":"22","author":"M. Mempel","year":"2003","unstructured":"Mempel M, Lina G, Hojka M, et al.: High prevalence of superantigens associated with the egc locus in Staphylococcus aureus isolates from patients with atopic eczema. Eur J Clin Microbiol Infect Dis 2003, 22: 306\u2013309.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"73_CR11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1081-1206(10)62222-3","volume":"87","author":"M.S. Schubert","year":"2001","unstructured":"Schubert MS: A superantigen hypothesis for the pathogenesis of chronic hypertrophic rhinosinusitis, allergic fungal sinusitis, and related disorders. Ann Allergy Asthma Immunol 2001, 87: 181\u2013188.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"73_CR12","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1067\/mai.2001.112374","volume":"107","author":"C. Bachert","year":"2001","unstructured":"Bachert C, Gevaert P, Holtappels G, et al.: Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 2001, 107: 607\u2013614.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR13","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2500\/105065898780708008","volume":"12","author":"C. Rudack","year":"1998","unstructured":"Rudack C, Stoll W, Bachert C: Cytokines in nasal polyposis, acute and chronic sinusitis. Am J Rhinol 1998, 12: 383\u2013388.","journal-title":"Am J Rhinol"},{"key":"73_CR14","doi-asserted-by":"crossref","first-page":"450","DOI":"10.3109\/00016489009122573","volume":"10","author":"P. Stierna","year":"1990","unstructured":"Stierna P, Carlsoo B: Histopathological observations in chronic maxillary sinusitis. Acta Otolaryngol (Stockh) 1990, 10: 450\u2013458.","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"73_CR15","first-page":"209","volume":"51","author":"C. Bachert","year":"1997","unstructured":"Bachert C, Van Cauwenberge PB: Inflammatory mechanisms in chronic sinusitis. Acta Otorhinolaryngol Belg 1997, 51: 209\u2013217.","journal-title":"Acta Otorhinolaryngol Belg"},{"key":"73_CR16","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1159\/000236875","volume":"106","author":"J.W. Georgitis","year":"1995","unstructured":"Georgitis JW, Matthews BL, Stone B: Chronic sinusitis: characterization of cellular influx and inflammatory mediators in sinus lavage. Int Arch Allergy lmmunol 1995, 106: 416\u2013421.","journal-title":"Int Arch Allergy lmmunol"},{"key":"73_CR17","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3109\/00016489309135860","volume":"13","author":"V.J. Lund","year":"1993","unstructured":"Lund VJ, Henderson B, Song Y: Involvement of cytokines and vascular adhesion molecules in the pathophysiology of fronto-ethmoidal mucoceles. Acta Otolaryngol (Stockh) 1993, 13: 540\u2013546.","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"73_CR18","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0091-6749(96)70100-8","volume":"98","author":"H. Suzuki","year":"1996","unstructured":"Suzuki H, Takahashi Y, Wataya H, et al.: Mechanism of neutrophil recruitment induced by IL-8 in chronic sinusitis. J Allergy Clin Immunol 1996, 98: 659\u2013670.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR19","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1084\/jem.173.3.771","volume":"173","author":"F. Bazzoni","year":"1991","unstructured":"Bazzoni F, Cassatella MA, Rossi F, et al.: Phagocytosing neutrophils produce and release high amounts of NAP-1\/IL-8. J Exp Med 1991, 173: 771\u2013774.","journal-title":"J Exp Med"},{"key":"73_CR20","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1073\/pnas.87.17.6758","volume":"87","author":"D.B. Dubravec","year":"1990","unstructured":"Dubravec DB, Spriggs DR, Mannick JA, Rodrick ML: Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor a. Proc Natl Acad Sci U S A 1990, 87: 6758\u20136761.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"73_CR21","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0091-6749(05)80123-X","volume":"86","author":"K. Hisamatsu","year":"1990","unstructured":"Hisamatsu K, Ganbo T, Nakazawa T, et al.: Cytotoxicity of human eosinophil granule major basic protein to human nasal sinus mucosa in vitro. J Allergy Clin Immunol 1990, 86: 52\u201363.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR22","doi-asserted-by":"crossref","first-page":"837","DOI":"10.4049\/jimmunol.140.3.837","volume":"140","author":"A. Lindemann","year":"1988","unstructured":"Lindemann A, Riedel D, Oster W, et al.: Granulocyte\/macrophage colony-stimulating factor induces interleukin-1 production by human polymorphonuclear neutrophils. J Immunol 1988, 140: 837\u2013839.","journal-title":"J Immunol"},{"key":"73_CR23","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/0091-6749(88)90944-X","volume":"81","author":"S.L. Harlin","year":"1988","unstructured":"Harlin SL, Ansel DG, Lane SR, et al.: A clinical and pathologic study of chronic sinusitis: the role of the eosinophi1. J Allergy Clin Immunol 1988, 81: 867\u2013875.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR24","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1288\/00005537-199410000-00011","volume":"104","author":"E. Tokushige","year":"1994","unstructured":"Tokushige E, Itoh K, Ushikai M, et al.: Localization of IL-1 beta mRNA and cell adhesion molecules in the maxillary sinus mucosa of patients with chronic sinusitis. Laryngoscope 1994, 104: 1245\u20131250.","journal-title":"Laryngoscope"},{"key":"73_CR25","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1067\/mai.2002.122458","volume":"109","author":"A. Ten Brinke","year":"2002","unstructured":"Ten Brinke A, Grootendorst DC, Schmidt JT, et al.: Chronic sinusitis in severe asthma is related to sputum eosinophilia. J Allergy Clin Immunol 2002, 109: 621\u2013626.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1067\/mai.2001.111593","volume":"107","author":"M. Bresciani","year":"2001","unstructured":"Bresciani M, Paradis L, Des Roches A, et al.: Rhinosinusitis in severe asthma. J Allergy Clin Immunol 2001, 107: 73\u201380.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR27","doi-asserted-by":"crossref","first-page":"339","DOI":"10.2500\/105065899781367546","volume":"13","author":"Y.G. Min","year":"1999","unstructured":"Min YG, Lee CH, Rhee CS, et al.: Increased expression of IL-4, IL-5, IFN-gamma, IL-6, IL-8, and TGF-beta mRNAs in maxillary mucosa of patients with chronic sinusitis. Am J Rhinol 1999, 13: 339\u2013343.","journal-title":"Am J Rhinol"},{"key":"73_CR28","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0385-8146(99)00042-5","volume":"27","author":"T. Nonoyama","year":"2000","unstructured":"Nonoyama T, Harada T, Shinogi J, et al.: Immuno-histochemical localization of cytokines and cell adhesion molecules in maxillary sinus mucosa in chronic sinusitis. Auris Nasus Larynx 2000, 27: 51\u201358.","journal-title":"Auris Nasus Larynx"},{"key":"73_CR29","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1288\/00005537-199410000-00011","volume":"104","author":"E. Tokushige","year":"1994","unstructured":"Tokushige E, Itoh K, Ushikai M, et al.: Localization of IL-1beta mRNA and cell adhesion molecules in the maxillary sinus mucosa of patients with chronic sinusitis. Laryngoscope 1994, 104: 1245\u20131250.","journal-title":"Laryngoscope"},{"issue":"Suppl","key":"73_CR30","first-page":"S115","volume":"30","author":"D.W. Kennedy","year":"2003","unstructured":"Kennedy DW: Two cases of Aspergillus sinusitis with bone destruction. Auris Nasus Larynx 2003, 30(Suppl): S115\u2013121.","journal-title":"Auris Nasus Larynx"},{"key":"73_CR31","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1097\/00005537-200211000-00008","volume":"112","author":"A.N. Khalid","year":"2002","unstructured":"Khalid AN, Hunt J, Perloff JR, Kennedy DW: The role of bone in chronic rhinosinusitis. Laryngoscope 2002, 112: 1951\u20131957.","journal-title":"Laryngoscope"},{"key":"73_CR32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2500\/105065897781446766","volume":"11","author":"W.E. Bolger","year":"1997","unstructured":"Bolger WE, Leonard D, Dick EJ Jr, Stierna P: Gram negative sinusitis: a bacteriologic and histologic study in rabbits. Am J Rhinol 1997, 11: 15\u201325.","journal-title":"Am J Rhinol"},{"key":"73_CR33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00130832-200302000-00001","volume":"3","author":"R. Pawankar","year":"2003","unstructured":"Pawankar R: Nasal polyposis: an update. Curr Opin Allergy Immunol 2003, 3: 1\u20136.","journal-title":"Curr Opin Allergy Immunol"},{"key":"73_CR34","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1046\/j.1365-2222.1998.00380.x","volume":"28","author":"D.L. Hamilos","year":"1998","unstructured":"Hamilos DL, Leung DYM, Huston DP, et al.: GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP). Clin Exp Allergy 1998, 28: 1145\u20131152.","journal-title":"Clin Exp Allergy"},{"key":"73_CR35","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0091-6749(95)70298-9","volume":"96","author":"D.L. Hamilos","year":"1995","unstructured":"Hamilos DL, Leung DYM, Wood R, et al.: Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis. J Allergy Clin Immunol 1995, 96: 537\u2013544.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR36","first-page":"3","volume":"1","author":"R. Pawankar","year":"2001","unstructured":"Pawankar R: Mast cells as or orchestrates of the allergic reaction: the IgE-IgE mast cell network. Curr Opin Allergy Clin Immunol 2001, 1: 3\u20136.","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"73_CR37","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1159\/000024209","volume":"119","author":"M. Nonaka","year":"1999","unstructured":"Nonaka M, Pawankar R, Saji F, Yagi T: Distinct expression of RANTES and GM-CSF by lipopolysaccharide in human nasal fibroblasts but not in other airway fibroblasts. Int Arch Allergy Immunol 1999, 119: 314\u2013321.","journal-title":"Int Arch Allergy Immunol"},{"key":"73_CR38","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1159\/000053811","volume":"125","author":"G. Lorenzo Di","year":"2001","unstructured":"Di Lorenzo G, Drago A, Esposito Pellitteri M, et al.: Measurement of inflammatory mediators of mast cells and eosinophils in native nasal lavage fluid in nasal polyposis. Int Arch Allergy Immunol 2001, 125: 164\u2013175.","journal-title":"Int Arch Allergy Immunol"},{"key":"73_CR39","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.jaci.2004.07.013","volume":"114","author":"T. Zele Van","year":"2004","unstructured":"Van Zele T, Gevaert P, Watelet JB, et al.: Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposis. J Allergy Clin Immunol 2004, 114: 981\u2013983.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR40","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jaci.2005.02.029","volume":"115","author":"C.A. P\u00e9rez-Novo","year":"2005","unstructured":"P\u00e9rez-Novo CA, Watelet JB, Claeys C, et al.: Prostaglandin, leukotriene, and lipoxin balance in chronic rhinosinusitis with and without nasal polyposis. J Allergy Clin Immunol 2005, 115: 1189\u20131196.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR41","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00130832-200402000-00005","volume":"4","author":"V. Kirtsreesakul","year":"2004","unstructured":"Kirtsreesakul V, Naclerio RM: Role of allergy in rhinosinusitis. Curr Opin Allergy Clin Immunol 2004, 4: 17\u201323.","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"73_CR42","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1136\/thx.47.7.499","volume":"47","author":"S. Montefort","year":"1992","unstructured":"Montefort S, Roberts JA, Beasley R, et al.: The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects. Thorax 1992, 47: 499\u2013503.","journal-title":"Thorax"},{"key":"73_CR43","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.jaci.2003.08.009","volume":"112","author":"J.U. Ponikau","year":"2003","unstructured":"Ponikau JU, Sherris DA, Kephart GM, et al.: Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis: is the histopathology similar to asthma? J Allergy Clin Immunol 2003, 112: 877\u2013882.","journal-title":"J Allergy Clin Immunol"},{"key":"73_CR44","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1097\/00005537-200303000-00004","volume":"113","author":"S.E. Sobol","year":"2003","unstructured":"Sobol SE, Fukakusa M, Christodoulopoulos P, et al.: Inflammation and remodeling of the sinus mucosa in children and adults with chronic sinusitis. Laryngoscope 2003, 113: 410\u2013414.","journal-title":"Laryngoscope"},{"key":"73_CR45","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1378\/chest.111.4.852","volume":"111","author":"A. Chetta","year":"1997","unstructured":"Chetta A, Foresi A, Del Donno M, et al.: Airways remodeling is a distinctive feature of asthma and is related to severity of disease. Chest 1997, 111: 852\u2013857.","journal-title":"Chest"},{"key":"73_CR46","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1097\/00005537-199711000-00017","volume":"107","author":"Y. Majima","year":"1997","unstructured":"Majima Y, Masuda S, Sakakura Y: Quantitative study of nasal secretory cells in normal subjects and patients with chronic sinusitis. Laryngoscope 1997, 107: 1515\u20131518.","journal-title":"Laryngoscope"},{"key":"73_CR47","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1177\/000348940311200205","volume":"112","author":"H.M. Lee","year":"2003","unstructured":"Lee HM, Choi JH, Chae SW, et al.: Expression of epidermal growth factor receptor and its ligands in chronic sinusitis. Ann Otol Rhinol Laryngol 2003, 112: 132\u2013138.","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"73_CR48","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1177\/000348949810701013","volume":"107","author":"T. Ishibashi","year":"1998","unstructured":"Ishibashi T, Tanaka T, Nibu K, et al.: Keratinocyte growth factor and its receptor messenger RNA expression in nasal mucosa and nasal polyps. Ann Otol Rhinol Laryngol 1998, 107: 885\u2013890.","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"73_CR49","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1001\/archotol.1997.01900100073010","volume":"123","author":"Y. Guo","year":"1997","unstructured":"Guo Y, Majima Y, Hattori M, et al.: Effects of functional endoscopic sinus surgery on maxillary sinus mucosa. Arch Otolaryngol Head Neck Surg 1997, 123: 1097\u20131100.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"73_CR50","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2500\/105065800781329573","volume":"14","author":"C. Bachert","year":"2000","unstructured":"Bachert C, Gevaert P, Holtappels G, et al.: Nasal polyposis: from cytokines to growth. Am J Rhinol 2000, 14: 279\u2013290.","journal-title":"Am J Rhinol"},{"key":"73_CR51","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1136\/thx.54.7.590","volume":"54","author":"B. Dahlen","year":"1999","unstructured":"Dahlen B, Shute J, Howarth P: Immunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthma. Thorax 1999, 54: 590\u2013596.","journal-title":"Thorax"},{"key":"73_CR52","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1046\/j.1365-2222.2002.01219.x","volume":"32","author":"C. Belleguic","year":"2002","unstructured":"Belleguic C, Corbel M, Germain N, et al.: Increased release of matrix metalloproteinase- 9 in the plasma of acute severe asthmatic patients. Clin Exp Allergy 2002, 32: 217\u2013223.","journal-title":"Clin Exp Allergy"},{"key":"73_CR53","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH771>3.0.CO;2-W","volume":"193","author":"E. Lechapt-Zalcman","year":"2001","unstructured":"Lechapt-Zalcman E, Coste A, d\u2019Ortho MP, et al.: Increased expression of matrix metalloproteinase-9 in nasal polyps. J Pathol 2001, 193: 233\u2013241.","journal-title":"J Pathol"},{"key":"73_CR54","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1046\/j.1398-9995.2003.00364.x","volume":"59","author":"J.B. Watelet","year":"2004","unstructured":"Watelet JB, Bachert C, Claeys C, Van Cauwenberge P: Matrix metalloproteinases MMP-7, MMP-9 and their tissue inhibitor TIMP-1: expression in chronic sinusitis vs nasal polyposis. Allergy 2004, 59: 54\u201360.","journal-title":"Allergy"},{"key":"73_CR55","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1097\/00005537-199707000-00018","volume":"107","author":"Q.P. Wang","year":"1997","unstructured":"Wang QP, Escudier E, Roudot-Thoraval F, et al.: Myofi-broblast accumulation induced by transforming growth factor-beta is involved in the pathogenesis of nasal polyps. Laryngoscope 1997, 107: 926\u2013931.","journal-title":"Laryngoscope"},{"key":"73_CR56","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1165\/ajrcmb\/3.5.507","volume":"3","author":"C.E. Brewster","year":"1990","unstructured":"Brewster CE, Howarth PH, Djukanovic R, et al.: Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 1990, 3: 507\u2013511.","journal-title":"Am J Respir Cell Mol Biol"},{"key":"73_CR57","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1111\/j.1365-2222.2004.1954.x","volume":"34","author":"M. Nonaka","year":"2004","unstructured":"Nonaka M, Pawankar R, Fukumoto A, et al.: Induction of eotaxin production by interleukin-4, interleukin-13 and lipopolysaccharide by nasal fibroblasts. Clin Exp Allergy 2004, 34: 804\u2013811.","journal-title":"Clin Exp Allergy"},{"key":"73_CR58","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1046\/j.1440-1592.2001.00229.x","volume":"50","author":"R. Djukanovic","year":"2001","unstructured":"Djukanovic R: Airway inflammation and repair in asthma. Allergol Int 2001, 50: 281\u2013294.","journal-title":"Allergol Int"}],"container-title":["Current Allergy and Asthma Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-007-0073-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11882-007-0073-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11882-007-0073-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:15:01Z","timestamp":1710375301000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11882-007-0073-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":58,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["73"],"URL":"https:\/\/doi.org\/10.1007\/s11882-007-0073-4","relation":{},"ISSN":["1529-7322","1534-6315"],"issn-type":[{"value":"1529-7322","type":"print"},{"value":"1534-6315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}