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This birth cohort study demonstrated that the tolerance effect related to early cat exposure is still present at the age of 18\u00a0years. More importantly, they show convincingly that exposure to cats in the first year of life is critical.","DOI":"10.1111\/j.1365-2222.2011.03747.x"},{"key":"288_CR57","doi-asserted-by":"crossref","unstructured":"\u2022 Olivieri M, Zock JP, Accordini S, Heinrich J, Jarvis D, Kunzli N, et al. Risk factors for new-onset cat sensitization among adults: a population-based international cohort study. J Allergy Clin Immunol. 2012;129(2):420-5. This is a longitudinal study of an adult cohort that was assembled as part of the European Community Respiratory Health Survey in 28 countries. Cat exposure before the age of 18 protected these participants against developing new cat sensitization. More important, they showed that cat acquisition during this follow-up increased cat sensitization, raising the complexity of the issues when advising parents about early life cat exposure.","DOI":"10.1016\/j.jaci.2011.10.044"},{"issue":"2","key":"288_CR58","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jpeds.2010.07.026","volume":"158","author":"TG Epstein","year":"2011","unstructured":"Epstein TG, Bernstein DI, Levin L, Khurana Hershey GK, Ryan PH, Reponen T, et al. Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth cohort. J Pediatr. 2011;158(2):265-71 e1-5.","journal-title":"J Pediatr"},{"issue":"4","key":"288_CR59","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jaci.2010.12.1122","volume":"127","author":"RA Wood","year":"2011","unstructured":"Wood RA, Bloomberg GR, Kattan M, Conroy K, Sandel MT, Dresen A, et al. 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This is a follow-up of a cohort of children with atopic dermatitis who participated in a double-blind eczema treatment trial and were then followed up The findings are interesting since this is the only high-risk longitudinal study that has shown that early life cat exposure is protective against any allergic disease in early childhood.","DOI":"10.2500\/aap.2012.33.3572"},{"issue":"8","key":"288_CR61","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1056\/NEJMoa1007302","volume":"364","author":"MJ Ege","year":"2011","unstructured":"Ege MJ, Mayer M, Normand A-C, Genuneit J, Cookson WOCM, Braun-Fahrl\u00e4nder C, et al. Exposure to environmental microorganisms and childhood asthma. 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