{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T16:09:16Z","timestamp":1793981356127,"version":"4.8.0"},"reference-count":81,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Atheroscler Rep"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s11883-022-01020-y","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T07:04:02Z","timestamp":1649660642000},"page":"471-481","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Are Clinicians Aggressive Enough in Treating Diabetes-Related Hyperlipidemia in Youth?"],"prefix":"10.1007","volume":"24","author":[{"given":"Sarah","family":"Jackson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Creo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8004-4924","authenticated-orcid":false,"given":"Seema","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"issue":"7","key":"1020_CR1","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.2337\/dc08-1871","volume":"32","author":"TS Church","year":"2009","unstructured":"Church TS, Thompson AM, Katzmarzyk PT, et al. Metabolic syndrome and diabetes, alone and in combination, as predictors of cardiovascular disease mortality among men. Diabetes Care. 2009;32(7):1289\u201394.","journal-title":"Diabetes Care"},{"issue":"1","key":"1020_CR2","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1161\/01.CIR.59.1.8","volume":"59","author":"WB Kannel","year":"1979","unstructured":"Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham study. Circulation. 1979;59(1):8\u201313.","journal-title":"Circulation"},{"key":"1020_CR3","doi-asserted-by":"crossref","unstructured":"Effect of intensive diabetes management on macrovascular events and risk factors in the Diabetes Control and Complications Trial. Am J Cardiol 1995, 75(14):894\u2013903.","DOI":"10.1016\/S0002-9149(99)80683-3"},{"key":"1020_CR4","unstructured":"Lawson ML, Gerstein HC, Tsui E, Zinman B: Effect of intensive therapy on early macrovascular disease in young individuals with type 1 diabetes. A systematic review and meta-analysis. Diabetes Care 1999, 22 Suppl 2:B35\u201339."},{"issue":"12","key":"1020_CR5","doi-asserted-by":"publisher","first-page":"e67","DOI":"10.1161\/CIR.0000000000000558","volume":"137","author":"EJ Benjamin","year":"2018","unstructured":"Benjamin EJ, Virani SS, Callaway CW, et al. Heart disease and stroke statistics-2018 update: a report from the American Heart Association. Circulation. 2018;137(12):e67\u2013492.","journal-title":"Circulation"},{"key":"1020_CR6","doi-asserted-by":"crossref","unstructured":"Soedamah-Muthu SS, Fuller JH, Mulnier HE, Raleigh VS, Lawrenson RA, Colhoun HM: High risk of cardiovascular disease in patients with type 1 diabetes in the U.K.: a cohort study using the general practice research database. Diabetes Care 2006, 29(4):798\u2013804.","DOI":"10.2337\/diacare.29.04.06.dc05-1433"},{"issue":"1","key":"1020_CR7","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1001\/jama.2014.16425","volume":"313","author":"SJ Livingstone","year":"2015","unstructured":"Livingstone SJ, Levin D, Looker HC, et al. Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008\u20132010. JAMA. 2015;313(1):37\u201344.","journal-title":"JAMA"},{"issue":"8","key":"1020_CR8","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1001\/jama.2021.11165","volume":"326","author":"JM Lawrence","year":"2021","unstructured":"Lawrence JM, Divers J, Isom S, et al. Trends in prevalence of type 1 and type 2 diabetes in children and adolescents in the US, 2001\u20132017. JAMA. 2021;326(8):717\u201327.","journal-title":"JAMA"},{"issue":"6","key":"1020_CR9","doi-asserted-by":"publisher","first-page":"161","DOI":"10.15585\/mmwr.mm6906a3","volume":"69","author":"J Divers","year":"2020","unstructured":"Divers J, Mayer-Davis EJ, Lawrence JM, et al. Trends in incidence of type 1 and type 2 diabetes among youths - selected counties and Indian reservations, United States, 2002\u20132015. MMWR Morb Mortal Wkly Rep. 2020;69(6):161\u20135.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"1020_CR10","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1007\/s00125-007-0921-8","volume":"51","author":"HD Margeirsdottir","year":"2008","unstructured":"Margeirsdottir HD, Larsen JR, Brunborg C, Overby NC, Dahl-Jorgensen K. Norwegian Study Group for Childhood D: High prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes: a population-based study. Diabetologia. 2008;51(4):554\u201361.","journal-title":"Diabetologia"},{"key":"1020_CR11","doi-asserted-by":"crossref","unstructured":"Rodriguez BL, Fujimoto WY, Mayer-Davis EJ, et al: Prevalence of cardiovascular disease risk factors in U.S. children and adolescents with diabetes: the SEARCH for diabetes in youth study. Diabetes Care 2006, 29(8):1891\u20131896.","DOI":"10.2337\/dc06-0310"},{"issue":"2","key":"1020_CR12","doi-asserted-by":"publisher","first-page":"434","DOI":"10.2337\/diacare.16.2.434","volume":"16","author":"J Stamler","year":"1993","unstructured":"Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 1993;16(2):434\u201344.","journal-title":"Diabetes Care"},{"key":"1020_CR13","doi-asserted-by":"crossref","unstructured":"Kim G, Divers J, Fino NF, et al: Trends in prevalence of cardiovascular risk factors from 2002 to 2012 among youth early in the course of type 1 and type 2 diabetes. The SEARCH for Diabetes in Youth Study. Pediatr Diabetes 2019, 20(6):693\u2013701.","DOI":"10.1111\/pedi.12846"},{"issue":"5","key":"1020_CR14","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1111\/pedi.12279","volume":"16","author":"AS Shah","year":"2015","unstructured":"Shah AS, Wadwa RP, Dabelea D, et al. Arterial stiffness in adolescents and young adults with and without type 1 diabetes: the SEARCH CVD study. Pediatr Diabetes. 2015;16(5):367\u201374.","journal-title":"Pediatr Diabetes"},{"issue":"8","key":"1020_CR15","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1097\/HJH.0b013e32833a6132","volume":"28","author":"EM Urbina","year":"2010","unstructured":"Urbina EM, Kimball TR, Khoury PR, Daniels SR, Dolan LM. Increased arterial stiffness is found in adolescents with obesity or obesity-related type 2 diabetes mellitus. J Hypertens. 2010;28(8):1692\u20138.","journal-title":"J Hypertens"},{"issue":"4","key":"1020_CR16","doi-asserted-by":"publisher","first-page":"881","DOI":"10.2337\/dc09-0747","volume":"33","author":"RP Wadwa","year":"2010","unstructured":"Wadwa RP, Urbina EM, Anderson AM, et al. Measures of arterial stiffness in youth with type 1 and type 2 diabetes: the SEARCH for diabetes in youth study. Diabetes Care. 2010;33(4):881\u20136.","journal-title":"Diabetes Care"},{"issue":"1","key":"1020_CR17","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1111\/dme.12335","volume":"31","author":"W Gu","year":"2014","unstructured":"Gu W, Huang Y, Zhang Y, et al. Adolescents and young adults with newly diagnosed type 2 diabetes demonstrate greater carotid intima-media thickness than those with type 1 diabetes. Diabet Med. 2014;31(1):84\u201391.","journal-title":"Diabet Med"},{"issue":"3","key":"1020_CR18","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.jpeds.2006.04.065","volume":"149","author":"AK Kershnar","year":"2006","unstructured":"Kershnar AK, Daniels SR, Imperatore G, et al. Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr. 2006;149(3):314\u20139.","journal-title":"J Pediatr"},{"issue":"2","key":"1020_CR19","doi-asserted-by":"publisher","first-page":"218","DOI":"10.2337\/diacare.29.02.06.dc05-0724","volume":"29","author":"KO Schwab","year":"2006","unstructured":"Schwab KO, Doerfer J, Hecker W, et al. Spectrum and prevalence of atherogenic risk factors in 27,358 children, adolescents, and young adults with type 1 diabetes: cross-sectional data from the German diabetes documentation and quality management system (DPV). Diabetes Care. 2006;29(2):218\u201325.","journal-title":"Diabetes Care"},{"issue":"3","key":"1020_CR20","doi-asserted-by":"publisher","first-page":"416","DOI":"10.2337\/dc08-1775","volume":"32","author":"J Guy","year":"2009","unstructured":"Guy J, Ogden L, Wadwa RP, et al. Lipid and lipoprotein profiles in youth with and without type 1 diabetes: the SEARCH for Diabetes in Youth case-control study. Diabetes Care. 2009;32(3):416\u201320.","journal-title":"Diabetes Care"},{"issue":"4","key":"1020_CR21","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1016\/j.jpeds.2005.04.068","volume":"147","author":"DM Maahs","year":"2005","unstructured":"Maahs DM, Maniatis AK, Nadeau K, Wadwa RP, McFann K, Klingensmith GJ. Total cholesterol and high-density lipoprotein levels in pediatric subjects with type 1 diabetes mellitus. J Pediatr. 2005;147(4):544\u20136.","journal-title":"J Pediatr"},{"issue":"2","key":"1020_CR22","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1034\/j.1399-5448.2000.010204.x","volume":"1","author":"M Polak","year":"2000","unstructured":"Polak M, Souchon PF, Benali K, Tubiana-Rufi N, Czernichow P. Type 1 diabetic children have abnormal lipid profiles during pubertal years. Pediatr Diabetes. 2000;1(2):74\u201381.","journal-title":"Pediatr Diabetes"},{"key":"1020_CR23","doi-asserted-by":"crossref","unstructured":"Maahs DM, Wadwa RP, McFann K, et al: Longitudinal lipid screening and use of lipid-lowering medications in pediatric type 1 diabetes. J Pediatr 2007, 150(2):146\u2013150, 150.e141\u2013142.","DOI":"10.1016\/j.jpeds.2006.10.054"},{"issue":"7","key":"1020_CR24","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1007\/s11892-014-0499-8","volume":"14","author":"P Bjornstad","year":"2014","unstructured":"Bjornstad P, Wadwa RP. Risks and benefits of statin use in young people with type 1 diabetes. Curr Diab Rep. 2014;14(7):499.","journal-title":"Curr Diab Rep"},{"issue":"4","key":"1020_CR25","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.jpeds.2008.05.062","volume":"153","author":"DM Maahs","year":"2008","unstructured":"Maahs DM, Wadwa RP, Bishop F, Daniels SR, Rewers M, Klingensmith GJ. Dyslipidemia in youth with diabetes: to treat or not to treat? J Pediatr. 2008;153(4):458\u201365.","journal-title":"J Pediatr"},{"issue":"8","key":"1020_CR26","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1111\/j.1464-5491.2008.02518.x","volume":"25","author":"JA Edge","year":"2008","unstructured":"Edge JA, James T, Shine B. Longitudinal screening of serum lipids in children and adolescents with Type 1 diabetes in a UK clinic population. Diabet Med. 2008;25(8):942\u20138.","journal-title":"Diabet Med"},{"issue":"3","key":"1020_CR27","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1590\/2359-3997000000040","volume":"59","author":"TK Homma","year":"2015","unstructured":"Homma TK, Endo CM, Saruhashi T, et al. Dyslipidemia in young patients with type 1 diabetes mellitus. Arch Endocrinol Metab. 2015;59(3):215\u20139.","journal-title":"Arch Endocrinol Metab"},{"issue":"4","key":"1020_CR28","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1111\/bcp.13482","volume":"84","author":"F Ahmadizar","year":"2018","unstructured":"Ahmadizar F, Souverein P, de Boer A. Maitland-van der Zee AH: Undertreatment of hypertension and hypercholesterolaemia in children and adolescents with type 1 diabetes: long-term follow-up on time trends in the occurrence of cardiovascular disease, risk factors and medications use. Br J Clin Pharmacol. 2018;84(4):776\u201385.","journal-title":"Br J Clin Pharmacol"},{"key":"1020_CR29","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s13633-020-00081-7","volume":"2020","author":"G Kim","year":"2020","unstructured":"Kim G, DeSalvo D, Guffey D, et al. Dyslipidemia in adolescents and young adults with type 1 and type 2 diabetes: a retrospective analysis. Int J Pediatr Endocrinol. 2020;2020:11.","journal-title":"Int J Pediatr Endocrinol"},{"key":"1020_CR30","doi-asserted-by":"crossref","unstructured":"Greenup E, Sunil B, Barr MM, Ashraf AP: Glycaemic control and outcomes in children with type 2 diabetes diagnosed at or before 10 years of age. Endocrinology, Diabetes and Metabolism 2021, 4(2).","DOI":"10.1002\/edm2.192"},{"issue":"6","key":"1020_CR31","first-page":"42","volume":"65","author":"A Amutha","year":"2017","unstructured":"Amutha A, Pradeepa R, Chella KS, Anjana RM, Unnikrishnan R, Mohan V. Lipid profile in childhood-and youth-onset type 2 diabetes and their association with microvascular complications. J Assoc Physicians India. 2017;65(6):42\u20137.","journal-title":"J Assoc Physicians India"},{"issue":"6","key":"1020_CR32","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.2337\/dc12-2388","volume":"36","author":"Group TS","year":"2013","unstructured":"Group TS. Lipid and inflammatory cardiovascular risk worsens over 3 years in youth with type 2 diabetes: the TODAY clinical trial. Diabetes Care. 2013;36(6):1758\u201364.","journal-title":"Diabetes Care"},{"key":"1020_CR33","doi-asserted-by":"crossref","unstructured":"McGill HC, Jr., McMahan CA, Malcom GT, Oalmann MC, Strong JP: Effects of serum lipoproteins and smoking on atherosclerosis in young men and women. The PDAY Research Group. Pathobiological Determinants of Atherosclerosis in Youth. Arterioscler Thromb Vasc Biol 1997, 17(1):95\u2013106.","DOI":"10.1161\/01.ATV.17.1.95"},{"key":"1020_CR34","doi-asserted-by":"crossref","unstructured":"Berenson GS, Srinivasan SR, Bao W, Newman WP, 3rd, Tracy RE, Wattigney WA: Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 1998, 338(23):1650\u20131656.","DOI":"10.1056\/NEJM199806043382302"},{"issue":"5","key":"1020_CR35","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1111\/pedi.13021","volume":"21","author":"E Gourgari","year":"2020","unstructured":"Gourgari E, Stafford JM, D\u2019Agostino R Jr, et al. The association of low-density lipoprotein cholesterol with elevated arterial stiffness in adolescents and young adults with type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth study. Pediatr Diabetes. 2020;21(5):863\u201370.","journal-title":"Pediatr Diabetes"},{"issue":"2","key":"1020_CR36","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jpeds.2009.08.036","volume":"156","author":"J Harrington","year":"2010","unstructured":"Harrington J, Pena AS, Gent R, Hirte C, Couper J. Aortic intima media thickness is an early marker of atherosclerosis in children with type 1 diabetes mellitus. J Pediatr. 2010;156(2):237\u201341.","journal-title":"J Pediatr"},{"issue":"4","key":"1020_CR37","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/j.jpeds.2010.04.023","volume":"157","author":"B Trigona","year":"2010","unstructured":"Trigona B, Aggoun Y, Maggio A, et al. Preclinical noninvasive markers of atherosclerosis in children and adolescents with type 1 diabetes are influenced by physical activity. J Pediatr. 2010;157(4):533\u20139.","journal-title":"J Pediatr"},{"key":"1020_CR38","doi-asserted-by":"crossref","unstructured":"\u2022\u2022 American Diabetes A: 13. Children and adolescents: standards of medical care in diabetes-2021. Diabetes Care 2021, 44(Suppl 1):S180-S199. This publication highlights the latest guidelines for screening and treatment of hyperlipidemia in youth with diabetes.","DOI":"10.2337\/dc21-S013"},{"issue":"Suppl 27","key":"1020_CR39","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1111\/pedi.12742","volume":"19","author":"KC Donaghue","year":"2018","unstructured":"Donaghue KC, Marcovecchio ML, Wadwa RP, et al. ISPAD Clinical Practice Consensus Guidelines 2018: Microvascular and macrovascular complications in children and adolescents. Pediatr Diabetes. 2018;19(Suppl 27):262\u201374.","journal-title":"Pediatr Diabetes"},{"key":"1020_CR40","doi-asserted-by":"crossref","unstructured":"\u2022 Zeitler P, Arslanian S, Fu JF, et al. ISPAD Clinical Practice Consensus Guidelines 2018: Type 2 diabetes mellitus in youth. Pediatr Diabetes. 2018;19:28\u201346. This publication summarizes the recommended approach to management of hyperlipidemia in youth with type 2 diabetes.","DOI":"10.1111\/pedi.12719"},{"issue":"7","key":"1020_CR41","doi-asserted-by":"publisher","first-page":"2194","DOI":"10.2337\/diacare.26.7.2194","volume":"26","author":"A American Diabetes","year":"2003","unstructured":"American Diabetes A. Management of dyslipidemia in children and adolescents with diabetes. Diabetes Care. 2003;26(7):2194\u20137.","journal-title":"Diabetes Care"},{"issue":"20","key":"1020_CR42","doi-asserted-by":"publisher","first-page":"2701","DOI":"10.1002\/ajmg.a.32493","volume":"146A","author":"EE Petersen","year":"2008","unstructured":"Petersen EE, Mitchell AA, Carey JC, et al. Maternal exposure to statins and risk for birth defects: a case-series approach. Am J Med Genet A. 2008;146A(20):2701\u20135.","journal-title":"Am J Med Genet A"},{"issue":"2","key":"1020_CR43","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.pathol.2018.09.062","volume":"51","author":"A Langsted","year":"2019","unstructured":"Langsted A, Nordestgaard BG. Nonfasting versus fasting lipid profile for cardiovascular risk prediction. Pathology. 2019;51(2):131\u201341.","journal-title":"Pathology"},{"issue":"4","key":"1020_CR44","doi-asserted-by":"publisher","first-page":"607","DOI":"10.2337\/dc16-2193","volume":"40","author":"AS Shah","year":"2017","unstructured":"Shah AS, Maahs DM, Stafford JM, et al. Predictors of dyslipidemia over time in youth with type 1 diabetes: for the SEARCH for Diabetes in Youth study. Diabetes Care. 2017;40(4):607\u201313.","journal-title":"Diabetes Care"},{"issue":"2","key":"1020_CR45","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00125-007-0870-2","volume":"51","author":"VL Franklin","year":"2008","unstructured":"Franklin VL, Khan F, Kennedy G, Belch JJ, Greene SA. Intensive insulin therapy improves endothelial function and microvascular reactivity in young people with type 1 diabetes. Diabetologia. 2008;51(2):353\u201360.","journal-title":"Diabetologia"},{"key":"1020_CR46","doi-asserted-by":"crossref","unstructured":"Brady RP, Shah AS, Jensen ET, et al: Glycemic control is associated with dyslipidemia over time in youth with type 2 diabetes: The SEARCH for diabetes in youth study. Pediatr Diabetes 2021.","DOI":"10.1111\/pedi.13253"},{"key":"1020_CR47","doi-asserted-by":"crossref","unstructured":"Maahs DM, Dabelea D, D'Agostino RB, Jr., et al: Glucose control predicts 2-year change in lipid profile in youth with type 1 diabetes. J Pediatr 2013, 162(1):101\u2013107 e101.","DOI":"10.1016\/j.jpeds.2012.06.006"},{"issue":"2","key":"1020_CR48","first-page":"160","volume":"35","author":"F Cadario","year":"2012","unstructured":"Cadario F, Prodam F, Pasqualicchio S, et al. Lipid profile and nutritional intake in children and adolescents with Type 1 diabetes improve after a structured dietician training to a Mediterranean-style diet. J Endocrinol Invest. 2012;35(2):160\u20138.","journal-title":"J Endocrinol Invest"},{"key":"1020_CR49","doi-asserted-by":"crossref","unstructured":"Lennerz BS, Barton A, Bernstein RK, et al: Management of type 1 diabetes with a very low-carbohydrate diet. Pediatrics 2018, 141(6).","DOI":"10.1542\/peds.2017-3349"},{"key":"1020_CR50","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.diabres.2017.07.006","volume":"131","author":"Y Meng","year":"2017","unstructured":"Meng Y, Bai H, Wang S, Li Z, Wang Q, Chen L. Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: a systematic review and meta-analysis of randomized controlled trials. Diabetes Res Clin Pract. 2017;131:124\u201331.","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"1020_CR51","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1111\/pedi.12162","volume":"16","author":"AS Shah","year":"2015","unstructured":"Shah AS, Dolan LM, Dabelea D, et al. Change in adiposity minimally affects the lipid profile in youth with recent onset type 1 diabetes. Pediatr Diabetes. 2015;16(4):280\u20136.","journal-title":"Pediatr Diabetes"},{"key":"1020_CR52","doi-asserted-by":"crossref","unstructured":"Inge TH, Courcoulas AP, Helmrath MA: Five-year outcomes of gastric bypass in adolescents as compared with adults. Reply. N Engl J Med 2019, 381(9):e17.","DOI":"10.1056\/NEJMc1908751"},{"issue":"2","key":"1020_CR53","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1056\/NEJMoa1506699","volume":"374","author":"TH Inge","year":"2016","unstructured":"Inge TH, Courcoulas AP, Jenkins TM, et al. Weight loss and health status 3 years after bariatric surgery in adolescents. N Engl J Med. 2016;374(2):113\u201323.","journal-title":"N Engl J Med"},{"key":"1020_CR54","doi-asserted-by":"crossref","unstructured":"Michalsky MP, Inge TH, Jenkins TM, et al: Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics 2018, 141(2).","DOI":"10.1542\/peds.2017-2485"},{"issue":"7","key":"1020_CR55","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1016\/j.soard.2018.03.019","volume":"14","author":"JSA Pratt","year":"2018","unstructured":"Pratt JSA, Browne A, Browne NT, et al. ASMBS pediatric metabolic and bariatric surgery guidelines, 2018. Surg Obes Relat Dis. 2018;14(7):882\u2013901.","journal-title":"Surg Obes Relat Dis"},{"key":"1020_CR56","doi-asserted-by":"crossref","unstructured":"Armstrong SC, Bolling CF, Michalsky MP, Reichard KW, Section On Obesity SOS: Pediatric metabolic and bariatric surgery: evidence, barriers, and best practices. Pediatrics 2019, 144(6).","DOI":"10.1542\/peds.2019-3223"},{"issue":"11","key":"1020_CR57","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.2337\/dc16-1728","volume":"39","author":"SR Colberg","year":"2016","unstructured":"Colberg SR, Sigal RJ, Yardley JE, et al. Physical activity\/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes Care. 2016;39(11):2065\u201379.","journal-title":"Diabetes Care"},{"issue":"11","key":"1020_CR58","doi-asserted-by":"publisher","first-page":"2518","DOI":"10.2337\/dc06-1317","volume":"29","author":"NJ Snowling","year":"2006","unstructured":"Snowling NJ, Hopkins WG. Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients: a meta-analysis. Diabetes Care. 2006;29(11):2518\u201327.","journal-title":"Diabetes Care"},{"issue":"3","key":"1020_CR59","first-page":"542","volume":"55","author":"M Chimen","year":"2012","unstructured":"Chimen M, Kennedy A, Nirantharakumar K, Pang TT, Andrews R, Narendran P. What are the health benefits of physical activity in type 1 diabetes mellitus? A literature review Diabetologia. 2012;55(3):542\u201351.","journal-title":"A literature review Diabetologia"},{"issue":"1","key":"1020_CR60","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/1758-5996-2-47","volume":"2","author":"MA Salem","year":"2010","unstructured":"Salem MA, AboElAsrar MA, Elbarbary NS, ElHilaly RA, Refaat YM. Is exercise a therapeutic tool for improvement of cardiovascular risk factors in adolescents with type 1 diabetes mellitus? A randomised controlled trial. Diabetol Metab Syndr. 2010;2(1):47.","journal-title":"Diabetol Metab Syndr"},{"key":"1020_CR61","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1186\/s12944-015-0152-9","volume":"14","author":"PA Monteiro","year":"2015","unstructured":"Monteiro PA, Chen KY, Lira FS, et al. Concurrent and aerobic exercise training promote similar benefits in body composition and metabolic profiles in obese adolescents. Lipids Health Dis. 2015;14:153.","journal-title":"Lipids Health Dis"},{"issue":"Supplement 27","key":"1020_CR62","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1111\/pedi.12738","volume":"19","author":"CE Smart","year":"2018","unstructured":"Smart CE, Annan F, Higgins LA, Jelleryd E, Lopez M, Acerini CL. ISPAD Clinical Practice Consensus Guidelines 2018: Nutritional management in children and adolescents with diabetes. Pediatr Diabetes. 2018;19(Supplement 27):136\u201354.","journal-title":"Pediatr Diabetes"},{"issue":"13","key":"1020_CR63","doi-asserted-by":"publisher","first-page":"e603","DOI":"10.1161\/CIR.0000000000000618","volume":"139","author":"SD de Ferranti","year":"2019","unstructured":"de Ferranti SD, Steinberger J, Ameduri R, et al. Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association. Circulation. 2019;139(13):e603\u201334.","journal-title":"Circulation"},{"issue":"16","key":"1020_CR64","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1056\/NEJMoa1816454","volume":"381","author":"IK Luirink","year":"2019","unstructured":"Luirink IK, Wiegman A, Kusters DM, et al. 20-year follow-up of statins in children with familial hypercholesterolemia. N Engl J Med. 2019;381(16):1547\u201356.","journal-title":"N Engl J Med"},{"issue":"6","key":"1020_CR65","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1161\/CIRCULATIONAHA.106.671016","volume":"116","author":"J Rodenburg","year":"2007","unstructured":"Rodenburg J, Vissers MN, Wiegman A, et al. Statin treatment in children with familial hypercholesterolemia: the younger, the better. Circulation. 2007;116(6):664\u20138.","journal-title":"Circulation"},{"issue":"4","key":"1020_CR66","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1161\/CIRCULATIONAHA.116.025158","volume":"136","author":"M Braamskamp","year":"2017","unstructured":"Braamskamp M, Langslet G, McCrindle BW, et al. Effect of rosuvastatin on carotid intima-media thickness in children with heterozygous familial hypercholesterolemia: the CHARON study (hypercholesterolemia in children and adolescents taking rosuvastatin open label). Circulation. 2017;136(4):359\u201366.","journal-title":"Circulation"},{"issue":"12","key":"1020_CR67","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1016\/S0735-1097(02)02593-7","volume":"40","author":"S de Jongh","year":"2002","unstructured":"de Jongh S, Lilien MR. op\u2019t Roodt J, Stroes ES, Bakker HD, Kastelein JJ: Early statin therapy restores endothelial function in children with familial hypercholesterolemia. J Am Coll Cardiol. 2002;40(12):2117\u201321.","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"1020_CR68","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1001\/jama.292.3.331","volume":"292","author":"A Wiegman","year":"2004","unstructured":"Wiegman A, Hutten BA, de Groot E, et al. Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial. JAMA. 2004;292(3):331\u20137.","journal-title":"JAMA"},{"key":"1020_CR69","doi-asserted-by":"crossref","unstructured":"Vuorio A, Kuoppala J, Kovanen PT, et al: Statins for children with familial hypercholesterolemia. Cochrane Database Syst Rev 2017, 7:CD006401.","DOI":"10.1002\/14651858.CD006401.pub4"},{"issue":"18","key":"1020_CR70","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1056\/NEJMoa1703518","volume":"377","author":"ML Marcovecchio","year":"2017","unstructured":"Marcovecchio ML, Chiesa ST, Bond S, et al. ACE inhibitors and statins in adolescents with type 1 diabetes. N Engl J Med. 2017;377(18):1733\u201345.","journal-title":"N Engl J Med"},{"key":"1020_CR71","unstructured":"Schwab KO: Cardiovascular risk factors in diabetes outcome. Pediatric Diabetes 2017, Conference:43rd Annual Meeting of the International Society for Pediatric and Adolescent Diabetes , ISPAD 2017. Innsbruck Austria. 2018 (Supplement 2025) (pp 2019)."},{"key":"1020_CR72","unstructured":"Schwab KO, Doerfer J, Scheidt-Nave C, et al: Algorithm-based cholesterol monitoring in children with type 1 diabetes. Hormone Research in Paediatrics 2014, Conference:53rd Annual Meeting of the European Society for Paediatric Endocrinology, ESPE 2014. Dublin Ireland. Conference Publication: (var.pagings). 2082 (SUPPL. 2011) (pp 2102)."},{"key":"1020_CR73","doi-asserted-by":"crossref","unstructured":"Katz ML, Guo Z, Laffel LM: Management of hypertension and high low-density lipoprotein in pediatric type 1 diabetes. J Pediatr 2018, 197:140\u2013146 e112.","DOI":"10.1016\/j.jpeds.2017.11.059"},{"issue":"9374","key":"1020_CR74","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1016\/S0140-6736(03)13636-7","volume":"361","author":"R Collins","year":"2003","unstructured":"Collins R, Armitage J, Parish S, Sleigh P, Peto R. Heart Protection Study Collaborative G: MRC\/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361(9374):2005\u201316.","journal-title":"Lancet"},{"key":"1020_CR75","doi-asserted-by":"crossref","unstructured":"Wang LL, Wang Q, Hong Y, et al: The effect of low-carbohydrate diet on glycemic control in patients with type 2 diabetes mellitus. Nutrients 2018, 10(6).","DOI":"10.3390\/nu10060661"},{"issue":"7","key":"1020_CR76","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1111\/dme.13322","volume":"34","author":"T Candler","year":"2017","unstructured":"Candler T, Mahmoud O, Edge J, Hamilton-Shield J. Hypercholesterolaemia screening in type 1 diabetes: a difference of opinion. Diabet Med. 2017;34(7):983\u20136.","journal-title":"Diabet Med"},{"issue":"3","key":"1020_CR77","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.jpeds.2013.10.027","volume":"164","author":"DB Dixon","year":"2014","unstructured":"Dixon DB, Kornblum AP, Steffen LM, Zhou X, Steinberger J. Implementation of lipid screening guidelines in children by primary pediatric providers. J Pediatr. 2014;164(3):572\u20136.","journal-title":"J Pediatr"},{"issue":"6","key":"1020_CR78","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1111\/dme.13090","volume":"33","author":"PJ O'Connor","year":"2016","unstructured":"O\u2019Connor PJ, Sperl-Hillen JM, Fazio CJ, Averbeck BM, Rank BH, Margolis KL. Outpatient diabetes clinical decision support: current status and future directions. Diabet Med. 2016;33(6):734\u201341.","journal-title":"Diabet Med"},{"key":"1020_CR79","doi-asserted-by":"crossref","unstructured":"Sim LL, Ban KH, Tan TW, Sethi SK, Loh TP: Development of a clinical decision support system for diabetes care: A pilot study. PLoS One 2017, 12(2):e0173021.","DOI":"10.1371\/journal.pone.0173021"},{"issue":"3","key":"1020_CR80","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1161\/CIRCULATIONAHA.107.697201","volume":"117","author":"JT van Wyk","year":"2008","unstructured":"van Wyk JT, van Wijk MA, Sturkenboom MC, Mosseveld M, Moorman PW, van der Lei J. Electronic alerts versus on-demand decision support to improve dyslipidemia treatment: a cluster randomized controlled trial. Circulation. 2008;117(3):371\u20138.","journal-title":"Circulation"},{"issue":"2","key":"1020_CR81","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1111\/pedi.12771","volume":"20","author":"ML Katz","year":"2019","unstructured":"Katz ML, Guo Z, Cheema A, Laffel LM. Management of cardiovascular disease risk in teens with type 1 diabetes: Perspectives of teens with and without dyslipidemia and parents. Pediatr Diabetes. 2019;20(2):210\u20136.","journal-title":"Pediatr Diabetes"}],"container-title":["Current Atherosclerosis Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11883-022-01020-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11883-022-01020-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11883-022-01020-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T18:14:44Z","timestamp":1654193684000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11883-022-01020-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,11]]},"references-count":81,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["1020"],"URL":"https:\/\/doi.org\/10.1007\/s11883-022-01020-y","relation":{},"ISSN":["1523-3804","1534-6242"],"issn-type":[{"value":"1523-3804","type":"print"},{"value":"1534-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,11]]},"assertion":[{"value":"3 February 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}]}}